Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:5.99.1.2 (topoisomerase)
9,166 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA topoisomerase 0.091 DNA gyrase 0.042 topoisomerase I 0.027 topoisomerase II alpha 0.007 TOP2A 0.006 type I DNA topoisomerase 0.005 ICRF 0.005 DNA topoisomerase I 0.005 DNA topoisomerase 1 0.004 topoisomerase II beta 0.002 RMI1 0.002 TOP1 0.002 TOP2B 0.002 topo II beta 0.001 DNA topoisomerase III 0.001 TOP3 0.001 TDP1 0.001 RMI2 0.001 TOP2A protein 0.001 Tyrosyl-DNA phosphodiesterase 1 0.001 tyrosyl-DNA phosphodiesterase 1 0.001 TOP1mt 0.001 TOP1MT 0.001 SPO11 0.001 ICB1 0.001 MX2 0.001 P-glycoprotein 0.000 mitochondrial topoisomerase I 0.000 MLL 0.000 helicase 0.000 TOP3A 0.000 PICH 0.000 TOP3B 0.000 ATP 0.000 BLM 0.000 H2AX 0.000 Mariner transposase 0.000 DNA helicase 0.000 C9orf82 0.000 p53 0.000 more...

Disease cancer 0.001 leukemia 0.000 BLM 0.000 Therapy-related myelodysplastic syndrome 0.000 acute myeloid leukemia 0.000 CEM 0.000 tumor 0.000 vaccinia 0.000 L.donovani 0.000 secondary AML 0.000 ATM 0.000 MCF 0.000 recurrent PNET 0.000 mouse leukemia L1210 0.000 myelodysplastic syndrome 0.000 WRN 0.000 small cell lung cancer 0.000 breast cancer 0.000 MDS 0.000 Teratoma with malignant transformation 0.000 SCAN1 0.000 acute promyelocytic leukemia 0.000 colon cancer 0.000 lung cancer 0.000 Leukemia 0.000 ovarian cancer 0.000 lung carcinoma 0.000 acute leukemia 0.000 SMC 0.000 acute lymphoblastic leukemia 0.000 scleroderma 0.000 myeloid leukemia 0.000 carcinoma 0.000 non-small cell lung cancer 0.000 childhood ependymoma 0.000 TAS 0.000 Shope fibroma 0.000 PSS 0.000 APL 0.000 APL 0.000 more...

Symptom diarrhea 0.000 disturbed balance 0.000 collapse 0.000 ataxia 0.000 starvation 0.000 autodigestion 0.000 No adverse effect 0.000 asthenia 0.000 Halo 0.000 nausea and vomiting 0.000 decreased appetite 0.000 ophthalmoplegia 0.000 menopausal symptoms 0.000 HSA 0.000 nausea 0.000 dyspnea 0.000 eds 0.000 hypoproteinemia 0.000 night sweats 0.000 muscle stiffness 0.000 vomiting 0.000 tonic-clonic seizure 0.000 skin damage 0.000 cerebellar ataxia 0.000 incoordination 0.000 apathy 0.000 chills 0.000 rhinorrhea 0.000 hyperoxia 0.000 dysuria 0.000 splenomegaly 0.000 fatigue 0.000 hoarseness 0.000 bone pain 0.000 colic 0.000 anorexia 0.000 cough 0.000 syncope 0.000 hepatosplenomegaly 0.000 headache 0.000 more...

Drug Etoposide 0.004 CPT-11 0.001 Dexrazoxane 0.001 Sobuzoxane 0.000 Adriamycin 0.000 BLM 0.000 Pixantrone 0.000 Irinotecan 0.000 TTC 0.000 Teniposide 0.000 Aclarubicin 0.000 Gemifloxacin 0.000 Gemifloxacin mesylate 0.000 Premafloxacin 0.000 Edotecarin 0.000 Sitafloxacin 0.000 MDS 0.000 DNase I 0.000 ADR 0.000 Podophyllotoxin 0.000 Moxifloxacin 0.000 Avelox 0.000 Idarubicin 0.000 Podophyllum 0.000 Tetrahydropyran 0.000 Tirapazamine 0.000 Irofulven 0.000 Mutagen 0.000 Ilmofosine 0.000 PZFX 0.000 Radicicol 0.000 Gatifloxacin 0.000 VCR 0.000 1,2,4-Triazole 0.000 Etoposide phosphate 0.000 Gemzar 0.000 Menogaril 0.000 VCR 0.000 Taxotere 0.000 AraC 0.000 more...

Enzyme topoisomerase 1.000 topoisomerase 0.910 P-glycoprotein 0.001 DNA polymerase 0.000 EC 5.99.1.1 0.000 PARP 0.000 DNA ligase 0.000 DNA ligase 0.000 ATPase 0.000 MDR 0.000 endonuclease 0.000 thymidylate synthase 0.000 RNA polymerase 0.000 hydroxypyruvate isomerase 0.000 ribonucleotide reductase 0.000 ribonucleotide reductase 0.000 caspase-3 0.000 CPT 0.000 caspase-2 0.000 CPT 0.000 RNase M5 0.000 kallikrein 10 0.000 protein kinase 0.000 phosphodiesterase 0.000 glutathione S-transferase 0.000 cdc2 0.000 caspase-2 0.000 CPT 0.000 ERK 0.000 polo-like kinase 1 0.000 proteasome 0.000 micrococcal nuclease 0.000 DNase II 0.000 polynucleotide kinase 0.000 nucleoside triphosphate phosphohydrolase 0.000 S-formylglutathione hydrolase 0.000 DNase 0.000 dihydrofolate reductase 0.000 endonuclease VII 0.000 dCMP hydroxymethylase 0.000 more...

Compound m-AMSA 0.013 VP-16 0.008 DNA 0.004 VM-26 0.003 ICRF-187 0.001 Camptothecin 0.001 Camptothecin 0.001 Camptothecin 0.001 Novobiocin 0.001 Topotecan 0.001 Merbarone 0.001 SN-38 0.001 Topotecan 0.001 Ellipticine 0.001 CPT-11 0.001 Adriamycin 0.000 Psorospermin 0.000 CI-921 0.000 Fostriecin 0.000 ATP 0.000 ADR 0.000 Mitoxantrone 0.000 Mitoxantrone 0.000 acridine 0.000 MIC 0.000 Clorobiocin 0.000 BLM 0.000 6-bromo-9H-purine 0.000 C15H12O5 0.000 C15H12O5 0.000 8-Methoxycaffeine 0.000 Podophyllotoxin acetate 0.000 C15H12O5 0.000 Fagaronine 0.000 1,3-bis(4-morpholinylmethyl)-2-imidazolidinethione 0.000 C15H12O5 0.000 Kinamycin C 0.000 C15H12O5 0.000 N-ethylhydrazinecarbothioamide 0.000 C15H12O5 0.000 more...

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