Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:5.99.1.2 (topoisomerase)
 9,166 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DNA gyrase 1142
topoisomerase I 959
Mol 884
DNA topoisomerase 832
ATP 621
Sep 611
p53 368
P-glycoprotein 244
ATPase 227
DNA topoisomerase I 218
histone 189
TOP2A 183
helicase 182
MIC 176
thymus 159
topoisomerase II alpha 139
caspase-3 136
ICRF 124
endonuclease 118
NMR 117
polypeptide 117
DNA polymerase 111
PARP 104
p21 100
Bcl-2 99
H2AX 96
MLL 95
AML 93
ATM 87
telomeric 85
fused 84
Ki-67 77
DNase I 75
DNA-dependent protein kinase 70
TOP1 67
HER2 66
poly(ADP-ribose) polymerase 66
proteasome 66
Pseudomonas 65
ADP 63
MDR1 60
DNA helicase 59
Chk1 59
phosphodiesterase 59
BLM 58
DNA topoisomerase 1 56
ATR 55
colon carcinoma 55
c-myc 55
tyrosine kinase 55
type I DNA topoisomerase 53
SDS 52
BRCA1 50
epidermal growth factor receptor 50
DNA polymerase alpha 47
ubiquitin 47
histone H3 46
thymidylate synthase 45
histone deacetylase 44
mdr1 44
proliferating cell nuclear antigen 43
Pol 41
MDS 40
RNA polymerase II 40
bcl-2 40
Fas 39
glutathione S-transferase 39
MX2 39
GSH 39
estrogen receptor 38
glycoprotein 38
GST 38
ACS 38
cytochrome c 38
DNA ligase 37
osteosarcoma 37
dimeric 37
MRP 37
topoisomerase II beta 37
A-T 37
RMI1 36
tumor necrosis factor 35
cytokine 35
Chk2 35
lymphoid 34
Gen 34
ADR 34
annexin V 33
integrase 32
EGFR 32
nuclear protein 31
collagen 31
histone H1 31
threonine 31
SAR 30
cyclin B1 30
caspase-9 30
PI3K 29
TOP2B 29
CPT 29
cyclin D1 29
ribonucleotide reductase 29
TDP1 28
phosphatase 28
RNase 28
cytochrome P450 28
RAD51 28
promyelocytic leukemia 28
AML1 28
TOP 27
AMP 27
erbB-2 27
multidrug resistance-associated protein 27
SPO11 27
Rad51 26
ROS 26
vascular endothelial growth factor 26
cyclin 26
breakpoint cluster region 25
ras 25
mTOR 25
ataxia telangiectasia mutated 25
mer 25
P-gp 25
ABCC1 25
caspase-8 25
MAPK 25
neu 24
MIB 24
protein tyrosine kinase 24
PC-3 24
AKT 24
WAF1 24
serum albumin 24
DNA binding protein 24
ALL 24
p38 24
p16 24
thymidine kinase 23
GTP 23
tyrosyl-DNA phosphodiesterase 1 23
dihydrofolate reductase 23
TNF 22
cyclin A 22
PARP1 22
Rad50 22
WRN 22
A431 22
RNA polymerase I 21
TOP3 21
ara 21
p27 21
VEGF 21
LRP 21
cyclin-dependent kinase 21
DNA topoisomerase III 20
vimentin 20
DNA-binding protein 20
metallothionein 20
tRNA 20
proteasome inhibitor 20
PC3 19
survivin 19
endoplasmic reticulum 19
PARP-1 19
catalase 19
progesterone receptor 18
SMC 18
methyltransferase 18
topo II beta 18
CD95 18
RPA 17
mutant p53 17
GRP78 17
DNA-binding domain 17
alpha isoform 17
MRSA 17
twist 17
RMI2 17
Bloom syndrome 17
all-trans 17
ERK1 17
BRCA2 17
NAD 17
non-Hodgkin's lymphoma 17
JNK 17
SSB 16
heat shock protein 16
Mcl-1 16
RUNX1 16
reductase 16
nucleolin 16
phosphorylating 16
Tyrosyl-DNA phosphodiesterase 1 16
alkaline phosphatase 16
epidermal growth factor 16
ERCC1 16
MRP1 16
cyclin dependent kinase 15
zinc finger 15
Hsp90 15
THP 15
CK2 15
glutaredoxin 15
p13 15
MRE11 15
FAB 15
SUMO 15
E-cadherin 15
ESI 15
Ku70 15
CD34 15
histone H4 15
P450 15
DNA methyltransferase 15
DNA repair enzyme 15
peroxidase 15
pRb 14
bax 14
interacting protein 14
membrane-bound 14
PDB 14
STAT3 14
HDAC 14
Poly 14
E2F1 14
RNase H 14
53BP1 14
calmodulin 14
unknown function 14
granulocyte 13
ubiquitin ligase 13
erythroid 13
gut 13
fibronectin 13
TopBP1 13
multidrug resistance protein 13
SOD 13
myeloperoxidase 13
Sp1 13
CDK1 13
MST 13
ATP-binding cassette 13
CtIP 13
pol 13
MYC 13
BCRP 13
ICE 13
CPP32 12
FLT3 12
HSP70 12
PKC 12
RAD52 12
PML 12
DNase 12
ABCG2 12
CDK2 12
interferon 12
c-fos 12
DNA primase 12
ABC 12
MUS81 12
MDM2 12
Bax protein 12
c-Myc 12
APL 12
catenin 12
MAR 12
ORF 12
MEL 12
CDC2 11
BRAF 11
PTEN 11
RPMI 11
rhabdomyosarcoma 11
NADPH 11
TOP2A protein 11
GADD45 11
androgen receptor 11
DDP 11
Poly(ADP-ribose) polymerase 11
multidrug resistance associated protein 11
poly (ADP-ribose) polymerase 11
AF4 11
cyclin E 11
protein phosphatase 11
p16INK4a 11
MOLT 11
CTX 11
P1b 11
single-stranded DNA binding protein 11
DNA polymerase beta 11
Werner syndrome 11
proto-oncogene 11
membrane protein 11
spermatozoa 11
Met 11
VEGFR2 11
beta-globin 11
XPD 10
GAL1 10
lactate dehydrogenase 10
SWI 10
E2F-1 10
FISH 10
c-Jun 10
chimeric protein 10
PICH 10
Walker 10
hormone receptor 10
acetyltransferase 10
AF9 10
cytochrome 10
EGF receptor 10
housekeeping 10
H2A 10
IFN 10
DNA ligase IV 10
BAX 10
UTR 10
more...
Disease
cancer 2377
tumor 1054
leukemia 607
breast cancer 355
acute myeloid leukemia 250
carcinoma 202
MCF 186
lung cancer 164
vaccinia 129
ATM 129
lymphoma 122
myelodysplastic syndrome 117
adenocarcinoma 112
colon cancer 108
melanoma 102
ovarian cancer 99
lung carcinoma 89
BLM 87
CEM 82
acute lymphoblastic leukemia 81
carcinogenesis 80
non-small cell lung cancer 77
tumor growth 76
small cell lung cancer 73
hepatocellular carcinoma 73
Leukemia 73
prostate cancer 73
colorectal cancer 70
metastases 65
Mycobacterium 64
acute promyelocytic leukemia 57
tuberculosis 55
tumorigenesis 53
acute leukemia 53
HIV 53
SDS 52
PSS 50
glioma 50
neutropenia 47
neuroblastoma 44
glioblastoma 44
WRN 42
MDS 40
sarcoma 40
GSH 39
multiple myeloma 39
scleroderma 39
solid tumor 38
anemia 38
osteosarcoma 38
Klebsiella 36
thrombocytopenia 35
Mycoplasma 34
epithelial ovarian cancer 33
Haemophilus 33
myeloid leukemia 32
squamous cell carcinoma 32
cervical cancer 30
SAR 30
tumor progression 30
infectious diseases 29
retinoblastoma 29
gastric cancer 29
leukemogenesis 28
secondary AML 28
leishmaniasis 26
myelosuppression 26
herpes simplex 26
Hodgkin's disease 26
pneumonia 25
malaria 25
Fanconi 24
chronic myeloid leukemia 24
pancreatic cancer 24
cold 22
immunodeficiency 22
fibrosarcoma 22
lymphoblastic leukemia 21
AIDS 20
non-Hodgkin's lymphoma 20
Epstein 19
DDP 18
suicide 18
SMC 18
bladder cancer 18
erythroleukemia 18
B-cell lymphoma 17
systemic lupus erythematosus 17
virus infection 17
MRSA 17
renal cell carcinoma 17
brain tumor 17
chronic lymphocytic leukemia 16
TAS 15
liver cancer 15
dysplasia 15
metastatic breast cancer 15
leukopenia 15
mammary tumor 14
xeroderma pigmentosum 14
TAM 14
liver cancer 14
primary tumor 14
PML 14
PDB 14
autism 13
sepsis 13
testicular cancer 12
gonococcal 12
Ewing's sarcoma 12
heart failure 12
MAR 12
cardiomyopathy 12
APL 12
APL 12
APL 12
hematologic malignancies 12
neuropathy 11
African swine fever 11
rhabdomyosarcoma 11
hepatitis B 11
CTX 11
mouse leukemia L1210 11
mole 11
histiocytic lymphoma 10
renal cancer 10
smallpox 10
glioblastoma multiforme 10
autoimmune disease 10
CREST 10
endometrial cancer 10
Burkitt's lymphoma 10
pancytopenia 10
blast crisis 9
ABL 9
Infection 9
pulmonary fibrosis 9
Fanconi syndrome 9
interstitial lung disease 9
childhood cancer 9
congestive heart failure 9
connective tissue disease 9
multiple sclerosis 9
Blocking 9
schizophrenia 9
meningitis 9
histiocytic lymphoma 8
Hepatocellular carcinoma 8
aggressiveness 8
rheumatoid arthritis 8
Chlamydia 8
RTS 8
childhood ALL 8
African trypanosomiasis 8
skin cancer 8
genetic disorder 8
cytomegalovirus 8
APC 8
premature aging 8
Yersinia 8
bends 8
sepsis 8
chronic myelomonocytic leukemia 7
Staphylococcus aureus infection 7
Therapy-related myelodysplastic syndrome 7
mole 7
chronic bronchitis 7
stroke 7
adenoma 7
mantle cell lymphoma 7
urinary tract infection 7
MTS 7
acute monocytic leukemia 7
depression 7
epilepsy 7
salmonellosis 7
Legionella 7
SCID 7
TEM 7
Proteus 7
West 6
pheochromocytoma 6
Colon 6
Colon 6
Neuroblastoma 6
bacteremia 6
infertility 6
influenza 6
Colon 6
WT1 6
epithelial tumor 6
germ cell tumor 6
medulloblastoma 6
recurrent ovarian cancer 6
worms 6
Chagas 6
Best 6
chronic lymphocytic leukemia 6
oral cancer 6
molluscum contagiosum 6
HP1 6
Alzheimer's disease 6
Neuroblastoma 6
aggression 6
teratoma 6
TEM 6
cervical intraepithelial neoplasia 5
Angelman syndrome 5
pulmonary hypertension 5
L.donovani 5
stromal tumors 5
AAA 5
bacterial conjunctivitis 5
multiple endocrine neoplasia 5
hypertension 5
cirrhosis 5
arthritis 5
adult T-cell leukemia/lymphoma 5
CAP 5
Shope fibroma 5
Melanoma 5
SARS 5
typhoid 5
XPF 5
carcinoma in situ 5
ductal carcinoma in situ 5
HGF 5
esophageal cancer 5
plaque 5
Kaposi's sarcoma 5
RAEB 5
cystitis 5
second cancer 5
esophageal cancer 5
residual disease 5
seminoma 5
diabetes 5
abdominal aortic aneurysm 5
rash 5
XPD 5
mastocytoma 5
fits 5
Robinson 5
mastitis 4
Glioblastoma 4
rare disease 4
follicular lymphoma 4
malnutrition 4
hepatoblastoma 4
stomatitis 4
bacterial infection 4
idiopathic pulmonary fibrosis 4
cholera 4
Syndrome 4
Adhesion 4
pituitary tumor 4
astrocytoma 4
mimicry 4
carcinomatosis 4
Raynaud 4
Raynaud's phenomenon 4
minimal residual disease 4
fungal infection 4
Osteosarcoma 4
Osteosarcoma 4
SEM 4
trisomy 4
EPI 4
dehydration 4
mesothelioma 4
Hippel 4
AML/MDS 4
candidiasis 4
renal disease 4
agranulocytosis 4
RP4 4
osteoporosis 4
meningioma 4
adult AML 4
conjunctivitis 3
skin disease 3
adrenocortical carcinoma 3
glomerulonephritis 3
Spinocerebellar ataxia 3
psoriasis 3
CHR 3
lymphoproliferative disorders 3
lymphopenia 3
uterine cancer 3
systemic disease 3
vasculitis 3
juvenile rheumatoid arthritis 3
neurofibromatosis 3
abortion 3
L. infantum 3
neurological disease 3
hemophagocytic lymphohistiocytosis 3
Lyme disease 3
adenocarcinoma of the pancreas 3
Still 3
babesiosis 3
ischemia 3
synovial sarcoma 3
lung disease 3
adenocarcinoma of the lung 3
pertussis 3
encephalopathy 3
human papilloma virus 3
human papilloma virus 3
uterine cervix 3
cervical adenocarcinoma 3
photosensitivity 3
myeloproliferative disorders 3
liposarcoma 3
FAS 3
addiction 3
atherosclerosis 3
tuberous sclerosis 3
neoplastic transformation 3
ependymoma 3
more...
Symptom
diarrhea 40
collapse 20
starvation 17
ataxia 14
dyspnea 10
nausea 10
vomiting 9
nausea and vomiting 8
fatigue 8
pain 7
headache 6
seizures 6
ophthalmoplegia 4
cough 4
abdominal pain 4
asthenia 4
HSA 3
anorexia 3
weakness 3
splenomegaly 3
apathy 2
menopausal symptoms 2
erythema 2
hyperoxia 2
syncope 2
cerebellar ataxia 2
chills 2
decreased appetite 2
hoarseness 1
night sweats 1
hepatomegaly 1
muscle stiffness 1
bone pain 1
No adverse effect 1
eds 1
Halo 1
autodigestion 1
hepatosplenomegaly 1
skin damage 1
incoordination 1
sleepiness 1
disturbed balance 1
dysuria 1
paresthesia 1
hypoproteinemia 1
rhinorrhea 1
functional recovery 1
exhaustion 1
tonic-clonic seizure 1
discomfort 1
discomfort 1
hypotonia 1
anesthesia 1
colic 1
Drug
Etoposide 196
Adriamycin 111
CPT-11 93
DNase I 75
TTC 60
BLM 58
lysine 55
Irinotecan 41
caffeine 40
MDS 40
Mutagen 39
ADR 34
Asn 32
Dexrazoxane 27
ROS 26
Gel 18
ampicillin 15
Taxol 15
CTX 14
Gemifloxacin 13
Herceptin 13
Moxifloxacin 12
VCR 12
ABC 12
Glutathione 12
Teniposide 12
CTX 11
CTX 11
Docetaxel 10
ADM 10
GEO 10
VCR 10
Aclarubicin 9
AraC 9
MAP 9
Pixantrone 8
Dermatol 8
Ofloxacin 7
Idarubicin 7
Cardiovasc 7
Podophyllotoxin 7
Taxotere 7
Sitafloxacin 6
Podophyllum 6
TEL 6
Leaf 6
ascorbate 6
CSF 5
EPI 5
Gatifloxacin 5
G-CSF 5
Tirapazamine 4
Enrofloxacin 4
ACT 4
NADH 4
MRC 4
Sobuzoxane 4
Alanine 4
Vorinostat 4
Gemzar 4
Myricetin 4
Vinorelbine 4
ETS 4
AZT 4
AZT 4
Ranitidine 3
Gefitinib 3
Monit 3
Ouabain 3
Bortezomib 3
Lovastatin 3
Fluconazole 3
Paraffin 3
Compound 9 3
PCP 3
IL-2 3
Radicicol 3
CED 3
CDP 3
lactose 2
Dihydro 2
Gemifloxacin mesylate 2
NaI 2
-deoxyadenosine 2
Fludarabine 2
CFS 2
NaI 2
CaCl2 2
p75 2
Avelox 2
CaCl2 2
Photofrin 2
FLP 2
Dronedarone 2
Irofulven 2
Itraconazole 2
Filgrastim 2
Fraction 2
Fragment 2
NaI 2
Bevacizumab 2
Emodin 2
Pentostam 2
Filgrastim 2
L-tyrosine 2
CaCl2 2
CoCl2 2
G418 2
CAM 2
Emodin 2
Meth 2
Gleevec 2
NaI 2
Cremophor EL 2
NH3 2
Doxycycline 2
NOV 2
CoCl2 2
Navelbine 2
Xeloda 2
TAC 2
AMC 2
Gadoteridol 1
Rauwolfia serpentina 1
Azithromycin 1
HCH 1
balanced salt solution 1
CTC 1
Artesunate 1
Phosphatidylserine 1
Poudre 1
Zoledronic acid 1
NovoSeven 1
MOF 1
Fluorescein 1
R1881 1
Retinoic acid 1
Swertia 1
Glucantime 1
Forskolin 1
Rituximab 1
MTC 1
AGG 1
IFN-gamma 1
Gliadel 1
Retinoic Acid 1
Dasatinib 1
Dakar 1
Meropenem 1
FAD 1
THF 1
Edotecarin 1
Amiloride 1
Premafloxacin 1
Clofibrate 1
FeCl3 1
Atovaquone 1
Zevalin 1
Tarivid 1
ICI 1
Cetuximab 1
ROC 1
Flavopiridol 1
IFN-beta 1
Epidoxorubicin 1
GRF 1
Isotretinoin 1
IPM 1
ZnCl2 1
Compound 16 1
Meropenem 1
Etoposide phosphate 1
ID2 1
KCL 1
Novantrone 1
Diamminedichloroplatinum 1
Pyridoxal 1
Pirarubicin 1
Triclosan 1
Amifostine 1
1,2,4-Triazole 1
Oxaliplatin 1
Spectrum 1
Methylprednisolone 1
Menogaril 1
Vindesine 1
Vindesine 1
PZFX 1
vitamin E 1
Fluorescein 1
Amiloride 1
Atovaquone 1
Imatinib 1
Albumin 1
Norplant 1
Ilmofosine 1
Spectrum 1
EPA 1
Vitamin K 1
Pefloxacin 1
DEL 1
CTC 1
RFP 1
Tetrahydropyran 1
DEX 1
Trifluoperazine 1
citric acid 1
Vitamin B 1
MDM 1
DM1 1
Polysorbate 20 1
Nephron 1
Compound 19 1
Zoledronic acid 1
ZnCl2 1
DPA 1
Pemetrexed 1
Compound 15 1
Enzyme
topoisomerase 9166
topoisomerase 9094
P-glycoprotein 247
ATPase 232
DNA polymerase 174
protein kinase 140
RNA polymerase 138
ERK 130
PARP 120
endonuclease 118
caspase-3 101
mitogen-activated protein kinase 74
glutathione S-transferase 70
protein kinase C 68
proteasome 67
phosphodiesterase 66
MDR 57
DNA ligase 52
DNA ligase 52
thymidylate synthase 51
cdc2 42
luciferase 39
RNase 38
ACS 38
ribonucleotide reductase 37
RNase 34
reverse transcriptase 34
DNase 30
CPT 29
CPT 29
CPT 29
ribonucleotide reductase 29
peroxidase 27
dihydrofolate reductase 26
focal adhesion kinase 26
caspase-9 24
thymidine kinase 23
trypsin 22
catalase 22
caspase-8 21
micrococcal nuclease 20
caspase-1 20
DNA methyltransferase 19
alkaline phosphatase 17
polo-like kinase 1 15
RNase H 15
NQO1 15
proteinase K 15
caspase-2 14
beta-galactosidase 14
S1 nuclease 13
lactate dehydrogenase 12
caspase-2 12
calcineurin 12
MEK 12
beta-lactamase 12
carboxylesterase 10
glutathione peroxidase 10
polynucleotide kinase 9
MAP 8
phosphoinositide 3-kinase 8
APC 7
CYP3A4 7
demethylase 7
kinesin 7
DNase II 7
ornithine decarboxylase 7
glutathione reductase 7
deoxycytidine kinase 7
superoxide dismutase 6
deoxyribonuclease 6
phosphatidylinositol 3-kinase 6
protein phosphatase 2A 6
acetylcholinesterase 6
phosphorylase 6
ATP synthase 6
chloramphenicol acetyltransferase 6
ribonuclease 6
cathepsin B 6
hypoxanthine-guanine phosphoribosyltransferase 6
IKK 6
AMPK 6
neuraminidase 6
tyrosinase 6
ribonuclease 6
asparaginase 5
firefly luciferase 5
carbonic anhydrase 5
beta-glucuronidase 5
transcriptase 5
chymotrypsin 5
alanine aminotransferase 5
dUTPase 4
thioredoxin reductase 4
succinate dehydrogenase 4
creatine kinase 4
alcohol dehydrogenase 4
deoxyribonuclease 4
endonuclease VII 4
chitin synthase 4
IMP dehydrogenase 4
TdT 4
dipeptidyl peptidase IV 4
histone acetyltransferase 4
AP lyase 3
NADPH oxidase 3
complex I 3
thrombin 3
caspase-7 3
lambda exonuclease 3
diaphorase 3
PCP 3
lysozyme 3
histidine kinase 3
cathepsin L 3
chaperonin 3
aspartate aminotransferase 3
thymidine phosphorylase 3
dihydropyrimidine dehydrogenase 3
Protein 2 3
cytidine deaminase 3
MMP 3
phospholipase C 3
poly(A) polymerase 3
dihydropyrimidine dehydrogenase 3
caspase-7 3
aldehyde dehydrogenase 3
GSK 3
CD13 3
cathepsin D 3
sialidase 3
N-acetyltransferase 3
hyaluronidase 2
tissue plasminogen activator 2
pyruvate dehydrogenase 2
malate dehydrogenase 2
isocitrate dehydrogenase 2
prostate-specific antigen 2
CD10 2
transpeptidase 2
transglutaminase 2
aldehyde dehydrogenase 2
CAD 2
dCMP deaminase 2
PST 2
hyaluronidase 2
alanine racemase 2
Alternating 2
CAD 2
prolidase 2
CAD 2
plasmin 2
TSA 2
diaphorase 2
acid phosphatase 2
BMT 2
urokinase-type plasminogen activator 2
isocitrate dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
NO synthase 2
NAT 2
lysyl oxidase 2
histone demethylase 2
nucleoside triphosphate phosphohydrolase 2
glucose-6-phosphate dehydrogenase 2
3'-exonuclease 2
glyceraldehyde-3-phosphate dehydrogenase 2
dihydropteroate synthase 2
separase 2
CaMKII 2
farnesyltransferase 2
NOS 2
glyceraldehyde-3-phosphate dehydrogenase 2
PRE 2
matrix metalloproteinase 2 2
aldehyde dehydrogenase 2
caspase-6 2
FabH 2
farnesyltransferase 2
MEKK1 2
MTD 2
5'-nucleotidase 2
phospholipase D 2
ACE 2
cysteine synthase 2
Rex 2
aldehyde dehydrogenase 2
tryptophan 2,3-dioxygenase 2
GCA 2
cytochrome oxidase 2
lipoxygenase 2
PIP kinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
aldehyde dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
phospholipase A2 2
cholinesterase 2
invertase 1
enzyme X 1
ubiquitin-protein ligase 1
pyruvate formate-lyase 1
gamma-glutamylcysteine synthetase 1
spermidine/spermine N1-acetyltransferase 1
renin 1
glycerol-3-phosphate dehydrogenase 1
3'-phosphatase 1
choline acetyltransferase 1
HIV-1 protease 1
penicillopepsin 1
BAT 1
NADPH-diaphorase 1
tryptophanase 1
NADH dehydrogenase 1
NADPH oxidase 1
glutamate racemase 1
dCMP hydroxymethylase 1
furin 1
S-formylglutathione hydrolase 1
pyruvate oxidase 1
azoreductase 1
MAT 1
heme oxygenase 1
granzyme B 1
Pla 1
branched-chain aminotransferase 1
enoyl-ACP reductase 1
beta-glucosidase 1
pyruvate oxidase 1
disulfide reductase 1
gamma-glutamyl transpeptidase 1
coproporphyrinogen oxidase 1
cellobiohydrolase 1
citrate synthase 1
enoyl-ACP reductase 1
PAH 1
xanthine oxidase 1
peptidyl-prolyl cis-trans isomerase 1
nucleoside hydrolase 1
lipase 1
PDH 1
glucosylceramide synthase 1
thermolysin 1
urease 1
collagenase 1
hydroxypyruvate isomerase 1
urease 1
succinic dehydrogenase 1
endodeoxyribonuclease 1
cytosine deaminase 1
inosine triphosphatase 1
CPS 1
fumarate reductase 1
matriptase 1
deoxycytidine deaminase 1
MDH 1
acetyl-CoA carboxylase 1
ScpA 1
orotate phosphoribosyltransferase 1
pepsin 1
coproporphyrinogen III oxidase 1
thymidylate kinase 1
nicotinamide phosphoribosyltransferase 1
PNGase F 1
amidophosphoribosyltransferase 1
isopeptidase 1
EC 5.99.1.1 1
NCP 1
kallikrein 10 1
phosphatidylinositol 4-kinase 1
cyclohydrolase 1
carboxypeptidase Y 1
glutamate dehydrogenase 1
PHD 1
enolase 1
prolyl hydroxylase 1
ADP-ribosyltransferase 1
cathepsin G 1
glutamate dehydrogenase 1
pyruvate dehydrogenase 1
MDP 1
venom phosphodiesterase 1
papain 1
DSR 1
ADP-ribosyltransferase 1
p100 1
sucrase-isomaltase 1
glutamate dehydrogenase 1
ubiquinol-cytochrome c oxidoreductase 1
LIS 1
adenine phosphoribosyltransferase 1
thyroid peroxidase 1
monoamine oxidase 1
formate dehydrogenase 1
aconitase 1
aspartase 1
neutrophil elastase 1
GM3 synthase 1
triphosphatase 1
glycerol-3-phosphate dehydrogenase 1
Thy1 1
cruzipain 1
Lys4 1
endoglycosidase H 1
acyl-CoA oxidase 1
PDK1 1
C3 convertase 1
exonuclease V 1
MDH 1
pyruvate dehydrogenase 1
caspase-4 1
argininosuccinate lyase 1
prolyl-tRNA synthetase 1
PTPase 1
chitinase 1
peptide deformylase 1
caspase-6 1
pseudouridine synthase 1
PTR1 1
RNase M5 1
AMPK 1
more...
Compound
DNA 5828
Dec 645
ATP 621
VP-16 469
m-AMSA 246
tyrosine 234
oxygen 220
Clin 205
Adriamycin 185
MIC 176
salt 163
VM-26 153
phosphate 147
hydrogen 130
sodium 119
MTT 118
acridine 113
ADR 112
water 110
serine 109
bromide 100
lysine 98
CPT-11 92
MDA 87
alanine 86
calcium 82
Camptothecin 81
Camptothecin 80
Camptothecin 80
nitrogen 77
Mg2+ 76
SN-38 76
Phe 73
arginine 72
sulfate 67
Asp 66
ADP 66
cysteine 64
ADP 63
ADP 63
leucine 62
BLM 60
MDR 57
ADP-ribose 56
SDS 55
Topotecan 54
Topotecan 54
threonine 54
pyridine 53
quinoline 53
quinoline 52
copper 51
zinc 51
GSH 50
GSH 50
glucose 50
iron 50
pyrimidine 49
pyrimidine 49
Novobiocin 48
ICRF-187 47
Genistein 46
benzene 44
caffeine 40
acetate 39
ACS 38
galactose 38
ACS 38
Ciprofloxacin 37
His 36
iodine 35
Mitoxantrone 34
Mitoxantrone 34
DDP 31
CPT 31
retinoic acid 31
CPT 29
Ile 29
potassium 29
EDTA 28
formaldehyde 28
EDTA 28
AMP 27
PEG 27
NH2 26
formaldehyde 26
fluorine 26
Gly 26
methionine 25
naphthoquinone 24
naphthoquinone 24
naphthoquinone 24
naphthoquinone 24
naphthoquinone 24
naphthoquinone 24
2-(dimethylamino)ethyl 24
2-(dimethylamino)ethyl 24
dATP 24
dUTP 24
naphthoquinone 24
GTP 24
Ellipticine 24
hydroquinone 24
Hoechst 33342 23
TNF 22
5-FU 22
manganese 22
methyl methanesulfonate 21
proline 21
piperazine 20
MgCl2 20
chalcone 19
glutamate 19
NAD 19
DMSO 19
chlorine 19
glycerol 19
N-acetylcysteine 18
3-aminobenzamide 18
NAD 17
nitric oxide 17
anthracene 17
PEG 17
Vinca 17
H2O2 17
isoquinoline 17
phenol 16
ethanol 16
THP 16
Nalidixic acid 16
HCl 16
THP 15
Cu(II) 15
ammonium 15
C-3 15
cyanide 15
methane 15
myricetin 14
urea 14
PDB 14
tryptophan 14
Merbarone 14
CTX 14
BCNU 14
Ara-C 14
DEAE 14
methanol 14
Resveratrol 13
thiophene 13
glutamine 12
thiourea 12
Moxifloxacin 12
CAM 12
CI-921 11
NADPH 11
ethyl acetate 11
aniline 11
kaempferol 11
aspartic acid 11
cAMP 11
NADPH 11
phenazine 11
nickel 11
hydroxide 11
2-hydroxyethyl 10
Curcumin 10
2-hydroxyethyl 10
naphthalene 10
Benzene 10
2-hydroxyethyl 10
2-hydroxyethyl 10
tryptophan 10
uridine 10
2-hydroxyethyl 10
aldehyde 10
2-hydroxyethyl 10
tryptophan 10
aldehyde 10
2-hydroxyethyl 10
MEK 10
2-hydroxyethyl 10
tryptophan 10
silver 10
Verapamil 10
Fostriecin 10
Verapamil 10
ABL 9
Ara-C 9
glutamic acid 9
Tris 9
bis(2-chloroethyl) 9
Levofloxacin 9
bis(2-chloroethyl) 9
pyrene 9
bis(2-chloroethyl) 9
CAP 9
Daunorubicin 9
Histone 9
MAP 9
aspartic acid 9
UTP 9
chloroform 9
aspartic acid 9
selenium 9
asparagine 9
aspartic acid 9
MES 8
CTP 8
isoleucine 8
BCR 8
Norfloxacin 8
Tris 8
nicotinamide 8
CO2 8
MES 8
B17 8
acrylamide 8
aminomethyl 8
nitrate 8
piperidine 8
isoleucine 8
boron 8
piperidine 8
Guo 8
A 1 7
Ofloxacin 7
morpholine 7
Epirubicin 7
Methotrexate 7
quinazoline 7
Aphidicolin 7
phenanthridine 7
Podophyllotoxin 7
phenanthridine 7
Suramin 7
phenanthridine 7
quinazoline 7
Cycloheximide 7
Aphidicolin 7
COS 7
cobalt 7
cadmium 7
Podophyllotoxin 7
cyclohexane 7
benzo[c]phenanthridine 7
Trovafloxacin 7
MTS 7
gallic acid 7
beta-Lapachone 6
Thiamine 6
Estrogen 6
phosphorus 6
STP 6
acetonitrile 6
CBDCA 6
benzamide 6
ATC 6
1H-indole 6
6-12 6
PNP 6
SET 6
ATC 6
SCC 6
Optimal 6
phosphoserine 6
DFS 6
CBDCA 6
acetic acid 6
Sitafloxacin 6
Paclitaxel 6
[1,10]phenanthroline 6
Cryptolepine 6
Amonafide 6
ETH 6
1H-benzimidazole 6
TSC 6
TEM 6
hydroxylamine 6
Quinone 6
Ethidium bromide 6
PMA 6
Pac 6
TTP 6
TEL 6
Estrogen 6
vitamin D 6
A 3 6
diacetate 6
MTX 6
Triton X-100 5
dCTP 5
butyric acid 5
celastrol 5
Berenil 5
AAA 5
salicylic acid 5
Sucrose 5
Epigallocatechin gallate 5
Chloroquine 5
Cardiol 5
Gatifloxacin 5
TCA 5
TPA 5
DMF 5
cGMP 5
vinyl 5
Chloroquine 5
[1,10]phenanthroline 5
CAP 5
TPA 5
Docetaxel 5
butyric acid 5
ammonia 5
COX 5
Actinomycin D 5
DEK 5
1,2,4-benzenetriol 5
butyric acid 5
hydroxylamine 5
TOF 5
more...