Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:5.99.1.2 (topoisomerase)
9,166 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA topoisomerase 0.091 DNA gyrase 0.042 topoisomerase I 0.027 topoisomerase II alpha 0.007 TOP2A 0.006 type I DNA topoisomerase 0.005 ICRF 0.005 DNA topoisomerase I 0.005 DNA topoisomerase 1 0.004 topoisomerase II beta 0.002 RMI1 0.002 TOP1 0.002 TOP2B 0.002 topo II beta 0.001 DNA topoisomerase III 0.001 TOP3 0.001 TDP1 0.001 RMI2 0.001 TOP2A protein 0.001 Tyrosyl-DNA phosphodiesterase 1 0.001 more...

Disease cancer 0.001 leukemia 0.000 BLM 0.000 Therapy-related myelodysplastic syndrome 0.000 acute myeloid leukemia 0.000 CEM 0.000 tumor 0.000 vaccinia 0.000 L.donovani 0.000 secondary AML 0.000 ATM 0.000 MCF 0.000 recurrent PNET 0.000 mouse leukemia L1210 0.000 myelodysplastic syndrome 0.000 WRN 0.000 small cell lung cancer 0.000 breast cancer 0.000 MDS 0.000 Teratoma with malignant transformation 0.000 more...

Symptom diarrhea 0.000 disturbed balance 0.000 collapse 0.000 ataxia 0.000 starvation 0.000 autodigestion 0.000 No adverse effect 0.000 asthenia 0.000 Halo 0.000 nausea and vomiting 0.000 decreased appetite 0.000 ophthalmoplegia 0.000 menopausal symptoms 0.000 HSA 0.000 nausea 0.000 dyspnea 0.000 eds 0.000 hypoproteinemia 0.000 night sweats 0.000 muscle stiffness 0.000 more...

Drug Etoposide 0.004 CPT-11 0.001 Dexrazoxane 0.001 Sobuzoxane 0.000 Adriamycin 0.000 BLM 0.000 Pixantrone 0.000 Irinotecan 0.000 TTC 0.000 Teniposide 0.000 Aclarubicin 0.000 Gemifloxacin 0.000 Gemifloxacin mesylate 0.000 Edotecarin 0.000 Premafloxacin 0.000 Sitafloxacin 0.000 MDS 0.000 DNase I 0.000 ADR 0.000 Podophyllotoxin 0.000 more...

Enzyme topoisomerase 1.000 topoisomerase 0.910 P-glycoprotein 0.001 DNA polymerase 0.000 EC 5.99.1.1 0.000 PARP 0.000 DNA ligase 0.000 DNA ligase 0.000 ATPase 0.000 MDR 0.000 endonuclease 0.000 thymidylate synthase 0.000 RNA polymerase 0.000 hydroxypyruvate isomerase 0.000 ribonucleotide reductase 0.000 ribonucleotide reductase 0.000 caspase-3 0.000 CPT 0.000 caspase-2 0.000 CPT 0.000 more...

Compound m-AMSA 0.013 VP-16 0.008 DNA 0.004 VM-26 0.003 ICRF-187 0.001 Camptothecin 0.001 Camptothecin 0.001 Camptothecin 0.001 Novobiocin 0.001 Topotecan 0.001 Merbarone 0.001 SN-38 0.001 Topotecan 0.001 Ellipticine 0.001 CPT-11 0.001 Adriamycin 0.000 Psorospermin 0.000 CI-921 0.000 Fostriecin 0.000 ATP 0.000 more...

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