Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.6.1.2 (guanylate cyclase)
 8,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
guanylate cyclase 0.726
guanylyl cyclase 0.268
Guanylate cyclase 0.014
NPR-A 0.012
nitric oxide synthase 0.010
PKG 0.010
guanylin 0.009
NPR-B 0.009
C-type natriuretic peptide 0.008
GUCY2D 0.008
GCAP1 0.007
uroguanylin 0.006
GCAP2 0.006
soluble guanylyl cyclase 0.005
ROS-GC1 0.005
atrial natriuretic factor 0.004
GCAP 0.004
atrial natriuretic peptide 0.004
phosphodiesterase 0.004
natriuretic peptide 0.003
Guanylyl cyclase 0.003
cGMP phosphodiesterase 0.003
NPR-C 0.003
SIN 0.003
ANP 0.002
natriuretic peptide receptor A 0.001
adenylate cyclase 0.001
heat-stable enterotoxin receptor 0.001
CNP 0.001
ANF 0.001
GC-E 0.001
natriuretic peptide receptor B 0.001
recoverin 0.001
guanylyl cyclase C 0.001
guanylate cyclase activating protein 0.001
GC1 0.001
PDE5 0.001
GC-F 0.001
GUCA1A 0.001
cGMP-phosphodiesterase activity 0.001
neuronal nitric oxide synthase 0.001
natriuretic peptide clearance receptor 0.001
EDRF 0.001
GCAP3 0.001
BNP 0.001
GTP 0.001
adenylyl cyclase 0.001
retinal degeneration 3 0.000
SNAP 0.000
neurocalcin 0.000
NPR 0.000
cyclooxygenase 0.000
eNOS 0.000
PDE 0.000
endothelial nitric oxide synthase 0.000
AMP 0.000
GUCY1B3 0.000
ATP 0.000
calmodulin 0.000
guanylate cyclase-activating protein 2 0.000
vasodilator-stimulated phosphoprotein 0.000
heme oxygenase-1 0.000
bradykinin 0.000
PKG1 0.000
GUCA1B 0.000
CORD5 0.000
HO-2 0.000
NCS-1 0.000
NOC 0.000
GMP 0.000
neurocalcin delta 0.000
GUCY1A3 0.000
GUCY2C 0.000
GC2 0.000
G-protein-coupled receptor kinase 1 0.000
GUANYLATE CYCLASE 0.000
prostaglandin I2 (prostacyclin) receptor 0.000
guanylate cyclase 1, soluble, beta 3 0.000
COD3 0.000
membrane-bound 0.000
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Disease
NAME 0.004
PDE 0.000
Chronic idiopathic constipation 0.000
pulmonary hypertension 0.000
CORD5 0.000
CHEST 0.000
difficile; Clostridium 0.000
COD3 0.000
relaxation; bladder 0.000
hypertension 0.000
CORD6 0.000
LCA12 0.000
LCA 0.000
Cone dystrophy 0.000
erectile dysfunction 0.000
Pulmonary arterial hypertension 0.000
Congenital sodium diarrhea 0.000
Macular dystrophy 0.000
pertussis 0.000
Multiple carboxylase deficiency 0.000
Central areolar choroidal dystrophy 0.000
PAPA 0.000
Hereditary retinal dystrophies 0.000
irritable bowel syndrome 0.000
persistent pulmonary hypertension of the newborn 0.000
heart failure 0.000
Retinal degeneration 0.000
Unilateral renal artery stenosis 0.000
dual personality 0.000
ischemia 0.000
right heart failure 0.000
congestive heart failure 0.000
Biotin deficiency 0.000
AGS3 0.000
neuroblastoma 0.000
Endothelial dysfunction 0.000
ventricular hypertrophy 0.000
renin-dependent hypertension 0.000
NINA 0.000
Persistent pulmonary hypertension 0.000
Flashing 0.000
cholera 0.000
atherosclerosis 0.000
vascular dilation 0.000
blindness 0.000
Pineal gland 0.000
Pineal gland 0.000
Pineal gland 0.000
Myometrium 0.000
adrenocortical carcinoma 0.000
cholestatic cirrhosis 0.000
RAT 0.000
Tension 0.000
cardiovascular disease 0.000
vascular disease 0.000
hepatic encephalopathy 0.000
orphan disease 0.000
fluid overload 0.000
diabetes 0.000
achondroplasia 0.000
hypotension and shock 0.000
myocardial ischemia 0.000
E. coli septicemia 0.000
depression 0.000
SMC 0.000
sepsis 0.000
Postoperative ileus 0.000
aqueous humor 0.000
hypertensive cardiomyopathy 0.000
cardiac overload 0.000
Portopulmonary hypertension 0.000
sepsis 0.000
cerebral vasospasm 0.000
Purging 0.000
SFD 0.000
pheochromocytoma 0.000
GSH 0.000
Blocking 0.000
gastroparesis 0.000
retinal vascular occlusion 0.000
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Symptom
Simple constipation 0.000
constipation 0.000
diarrhea 0.000
chronic constipation 0.000
Functional abdominal pain 0.000
bloating 0.000
Functional constipation 0.000
angina 0.000
hyperoxia 0.000
pain 0.000
analgesia 0.000
Lower urinary tract symptoms 0.000
spasm 0.000
Anoxia 0.000
clonus 0.000
bladder pain 0.000
hypercapnia 0.000
despair 0.000
orofacial pain 0.000
acute pain 0.000
loss of balance 0.000
HSA 0.000
abdominal pain 0.000
hyperesthesia 0.000
abdominal cramps 0.000
Gastrointestinal symptoms 0.000
colic 0.000
seizures 0.000
anesthesia 0.000
exertional dyspnea 0.000
hypothermia 0.000
general problem 0.000
respiratory distress 0.000
headache 0.000
flushing 0.000
microbial colonization 0.000
functional recovery 0.000
urinary frequency 0.000
nasal congestion 0.000
polyuria 0.000
erythema 0.000
skin damage 0.000
starvation 0.000
photophobia 0.000
hypocapnia 0.000
abdominal discomfort 0.000
ataxia 0.000
discomfort 0.000
discomfort 0.000
tense 0.000
polydipsia 0.000
collapse 0.000
bradykinesia 0.000
hemoptysis 0.000
chest pain 0.000
epigastric pain 0.000
memory loss 0.000
dystonia 0.000
pelvic pain 0.000
dyspnea 0.000
acute stress 0.000
wheezing 0.000
ENT 0.000
hunger 0.000
myalgia 0.000
tinnitus 0.000
acidity 0.000
vertigo 0.000
arthralgia 0.000
tremor 0.000
syncope 0.000
dizziness 0.000
splenomegaly 0.000
nausea 0.000
thinning 0.000
agitation 0.000
back pain 0.000
stigma 0.000
anorexia 0.000
weakness 0.000
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Drug
Methylene blue 0.004
Sodium nitroprusside 0.003
nitroglycerin 0.001
Nitric Oxide 0.000
Nipradilol 0.000
Heme 0.000
Carperitide 0.000
N-Hydroxyguanidine 0.000
7-Nitroindazole 0.000
Viagra 0.000
Viagra 0.000
Leminoprazole 0.000
Molsidomine 0.000
Cicletanine 0.000
Forskolin 0.000
Quinaprilat 0.000
Avanafil 0.000
Equilin 0.000
Angiotensin II 0.000
Pentaerythritol tetranitrate 0.000
Indomethacin 0.000
L-Homoarginine 0.000
Nebivolol 0.000
Cardiovasc 0.000
Nesiritide 0.000
CaCl2 0.000
BH4 0.000
CaCl2 0.000
CaCl2 0.000
ETA 0.000
Regitine 0.000
Gly-Tyr-Gly 0.000
Aminoguanidine 0.000
ICI 0.000
Atropine 0.000
caffeine 0.000
Histamine 0.000
Ergometrine 0.000
PBZ 0.000
Iloprost 0.000
Ibudilast 0.000
Batroxobin 0.000
ascorbate 0.000
Rolipram 0.000
ROS 0.000
Trifluoperazine 0.000
Tegaserod 0.000
Omapatrilat 0.000
Vardenafil 0.000
Quisqualate 0.000
Ferrous sulfate 0.000
Ramelteon 0.000
Tegaserod 0.000
Timolol maleate 0.000
Treprostinil 0.000
Phosphoramidon 0.000
Ouabain 0.000
Glybenclamide 0.000
Malonaldehyde 0.000
Asn 0.000
Red ginseng 0.000
Ethanol 0.000
Nephron 0.000
Vinpocetine 0.000
Guanidine 0.000
Guanidine 0.000
Trental 0.000
Lead acetate 0.000
Luteinizing 0.000
Amiloride 0.000
Dronedarone 0.000
Salmon calcitonin 0.000
Bumetanide 0.000
Dihydroergotamine 0.000
Phentolamine 0.000
Carbenoxolone 0.000
NADH 0.000
Amiloride 0.000
Tranilast 0.000
Thiopentone 0.000
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Enzyme
guanylate cyclase 1.000
PKG 0.010
NO synthase 0.006
cGMP phosphodiesterase 0.004
phosphodiesterase 0.004
adenylate cyclase 0.001
protein kinase 0.001
NOS 0.001
heme oxygenase 0.000
PDE 0.000
EC 1.13.11.49 0.000
rhodopsin kinase 0.000
NADPH-diaphorase 0.000
protein kinase C 0.000
phospholipase C 0.000
isoflavone 7-O-glucosyltransferase 0.000
superoxide dismutase 0.000
lipoxygenase 0.000
2-hydroxyisoflavanone dehydratase 0.000
ATPase 0.000
cytidylate cyclase 0.000
mitogen-activated protein kinase 0.000
CD10 0.000
catalase 0.000
retinol isomerase 0.000
AMPK 0.000
2-hydroxyisoflavanone synthase 0.000
phospholipase A2 0.000
thrombin 0.000
lecithin-retinol acyltransferase 0.000
renin 0.000
steroid 11beta-hydroxylase 0.000
EC 5.3.3.2 0.000
CPT 0.000
CPT 0.000
xanthine oxidase 0.000
biliverdin reductase 0.000
SNO 0.000
CPT 0.000
GCA 0.000
ecdysone 20-monooxygenase 0.000
calcineurin 0.000
protein N-myristoyltransferase 0.000
6-pyruvoyltetrahydropterin synthase 0.000
NADPH oxidase 0.000
tyrosine hydroxylase 0.000
myosin light chain kinase 0.000
diaphorase 0.000
GMP synthase 0.000
tyrosylprotein sulfotransferase 0.000
protein phosphatase 2A 0.000
NADPH oxidase 0.000
MEK 0.000
CaMKII 0.000
diaphorase 0.000
carboxypeptidase S 0.000
ACE 0.000
isoflavone reductase 0.000
ADP-ribosyltransferase 0.000
ADP-ribosyltransferase 0.000
5'-nucleotidase 0.000
thromboxane synthase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
GTP cyclohydrolase I 0.000
NQO1 0.000
lysophosphatidylcholine acyltransferase 0.000
aldehyde dehydrogenase 0.000
ERK 0.000
AMP-activated protein kinase 0.000
hormone-sensitive lipase 0.000
EC 3.6.1.1 0.000
cytochrome P-450scc 0.000
prolinase 0.000
aconitase 0.000
anthocyanidin synthase 0.000
LipA 0.000
nitrite reductase 0.000
propionyl-CoA carboxylase 0.000
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Compound
cGMP 0.105
nitric oxide 0.016
GMP 0.009
8-Br-cGMP 0.006
Methylene blue 0.004
arginine 0.003
cAMP 0.001
sodium 0.001
calcium 0.001
DEA 0.001
DEA 0.001
DEA 0.001
BNP 0.000
GTP 0.000
NPR 0.000
DETA 0.000
AMP 0.000
Nitroprusside 0.000
ATP 0.000
Nitro-L-arginine 0.000
Sildenafil 0.000
Nicorandil 0.000
Nitroglycerin 0.000
adenylate 0.000
TEA 0.000
TEA 0.000
ACh 0.000
Vindorosine 0.000
5-Nitroisatin 0.000
D-NONOate 0.000
prostacyclin 0.000
potassium 0.000
Isatin 0.000
Heme 0.000
8-iso-PGF2beta 0.000
Tetrahydroneopterin 0.000
CO2 0.000
8-iso-PGE1 0.000
manganese 0.000
nitrate 0.000
hydroxylamine 0.000
hydroxylamine 0.000
Bradykinin 0.000
4-AP 0.000
cysteine 0.000
D-Arginine 0.000
Relaxant 0.000
NMDA 0.000
Sodium azide 0.000
noradrenaline 0.000
SB 200646 0.000
glutamate 0.000
LNO2 0.000
Lubiprostone 0.000
ADP 0.000
Protoporphyrin IX 0.000
Mg2+ 0.000
ADP 0.000
ADP 0.000
CIT 0.000
C7H9N3O3 0.000
Eudesmin 0.000
Caracemide 0.000
8-iso-PGE2 0.000
oxygen 0.000
Acetylcholine chloride 0.000
3-Chlorotyrosine 0.000
Capillarisin 0.000
Glibenclamide 0.000
Tetraethylammonium 0.000
AA861 0.000
ethanimidamide 0.000
2-aminoethyl diphenylborinate 0.000
2-aminoethyl diphenylborinate 0.000
salt 0.000
Carbachol 0.000
HM-5 0.000
Cromakalim 0.000
aldosterone 0.000
Piloty's acid 0.000
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