Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:4.6.1.2 (guanylate cyclase)
8,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein guanylate cyclase 6167 guanylyl cyclase 2279 nitric oxide synthase 1585 phosphodiesterase 772 ATP 556 Sep 554 Mol 531 atrial natriuretic peptide 478 natriuretic peptide 474 adenylate cyclase 471 PKG 453 atrial natriuretic factor 391 GTP 345 AMP 309 soluble guanylyl cyclase 282 C-type natriuretic peptide 273 cyclooxygenase 242 calmodulin 235 NPR-A 230 adenylyl cyclase 194 SIN 193 membrane-bound 190 hemoglobin 190 NPR-B 183 ANP 180 bradykinin 173 superoxide dismutase 168 Guanylate cyclase 161 guanylin 157 neuronal nitric oxide synthase 156 angiotensin II 147 ATPase 146 heme oxygenase-1 138 cGMP phosphodiesterase 133 inducible nitric oxide synthase 133 lipopolysaccharide 131 ADP 130 insulin 123 SNAP 123 catalase 118 uroguanylin 117 endothelial nitric oxide synthase 117 eNOS 110 endothelin-1 108 olfactory 107 GUCY2D 105 collagen 102 ANF 91 vascular endothelium 90 BNP 88 GMP 88 polypeptide 85 GCAP1 83 cytokine 83 NPR-C 82 NMDA receptor 82 thrombin 82 renin 81 CNP 81 PDE 79 NADPH 77 Gen 77 muscarinic receptor 74 PDE5 73 rhodopsin 72 Ang II 71 ROS-GC1 66 lipoxygenase 66 PKA 64 tumor necrosis factor 61 p38 60 5-hydroxytryptamine 60 Dictyostelium 60 GCAP2 59 Guanylyl cyclase 59 vasopressin 58 recoverin 57 substance P 55 HO-1 55 GCAP 54 more...

Disease NAME 646 hypertension 436 pulmonary hypertension 190 heart failure 139 ischemia 138 diabetes 113 cancer 94 pertussis 93 tumor 87 depression 85 PDE 79 atherosclerosis 78 erectile dysfunction 73 stroke 62 congestive heart failure 59 neuroblastoma 58 cardiovascular disease 58 irritable bowel syndrome 47 sepsis 47 sepsis 46 LCA 43 myocardial infarction 41 cholera 41 obesity 38 asthma 37 myocardial ischemia 36 GSH 36 ventricular hypertrophy 34 blindness 32 SDS 32 Pulmonary arterial hypertension 32 Alzheimer's disease 29 vascular disease 29 glioma 24 SEM 23 right heart failure 23 cirrhosis 23 coronary artery disease 23 uterus 23 heart disease 23 pheochromocytoma 22 hypercholesterolemia 21 cold 21 tumor growth 19 ATM 19 cystic fibrosis 19 acute myocardial infarction 18 Blocking 17 hyperglycemia 17 intraocular pressure 15 urethra 15 colorectal cancer 15 fits 14 inflammatory bowel disease 14 renal disease 14 carcinoma 14 PSS 14 hepatic encephalopathy 14 Endothelial dysfunction 14 type 2 diabetes 13 Parkinson's disease 13 hepatocellular carcinoma 13 metabolic syndrome 13 breast cancer 13 malaria 13 sickle cell disease 13 glaucoma 13 portal hypertension 12 idiopathic thrombocytopenic purpura 12 aqueous humor 12 persistent pulmonary hypertension of the newborn 12 retinitis pigmentosa 12 chronic renal failure 12 subarachnoid hemorrhage 12 tetanus 12 plaque 12 colitis 11 CHEST 11 retinopathy 11 colon cancer 11 more...

Symptom diarrhea 93 pain 90 constipation 49 angina 35 analgesia 24 anesthesia 22 seizures 19 abdominal pain 15 headache 14 chronic constipation 13 hyperoxia 13 spasm 11 bloating 10 hypothermia 8 respiratory distress 8 hypercapnia 8 starvation 7 discomfort 6 collapse 6 functional recovery 6 discomfort 6 erythema 5 acute pain 5 ataxia 5 chest pain 4 dyspnea 4 flushing 4 HSA 4 colic 3 despair 3 exertional dyspnea 3 weakness 2 polyuria 2 fatigue 2 orofacial pain 2 dystonia 2 nausea 2 Anoxia 2 clonus 2 acidity 2 hemoptysis 2 tremor 2 dizziness 1 acute stress 1 ENT 1 vertigo 1 tense 1 Simple constipation 1 pelvic pain 1 urinary frequency 1 hyperesthesia 1 wheezing 1 bladder pain 1 stigma 1 microbial colonization 1 Lower urinary tract symptoms 1 hypocapnia 1 arthralgia 1 polydipsia 1 back pain 1 abdominal cramps 1 thinning 1 splenomegaly 1 myalgia 1 abdominal discomfort 1 skin damage 1 memory loss 1 vomiting 1 nasal congestion 1 hunger 1 tinnitus 1 epigastric pain 1 Functional abdominal pain 1 agitation 1 anorexia 1 Functional constipation 1 syncope 1 Gastrointestinal symptoms 1 photophobia 1 loss of balance 1 more...

Drug nitroglycerin 221 Methylene blue 216 Sodium nitroprusside 160 Cardiovasc 157 Nitric Oxide 81 Heme 60 caffeine 39 ascorbate 36 ROS 32 lysine 31 Indomethacin 30 Angiotensin II 29 CaCl2 26 CaCl2 25 CaCl2 25 Forskolin 24 Nephron 22 ICI 20 NADH 20 Asn 20 Histamine 19 Ethanol 17 ETA 16 Viagra 15 Atropine 15 Gel 15 MAP 15 Viagra 13 BH4 12 Dermatol 12 CTX 11 IL-2 10 CSF 10 vitamin E 10 Ouabain 9 IFN-gamma 9 Nipradilol 8 PTH 7 FAD 7 EE2 6 7-Nitroindazole 6 Molsidomine 6 Fraction 6 Glutathione 6 Amiloride 5 Aminoguanidine 5 Amiloride 5 Iloprost 5 citric acid 5 Theophylline 5 Nebivolol 5 FeCl3 4 Bayer 4 Nephron 4 Estrogens 4 Luteinizing 4 Phentolamine 4 Rolipram 4 Cicletanine 4 Asthma 4 Trifluoperazine 4 Monit 4 CTX 4 Ringer's solution 4 NAG 4 CTX 4 -deoxyadenosine 3 Dial 3 Alanine 3 Nesiritide 3 NH3 3 Salbutamol 3 ALA 3 Carperitide 3 Pronase 3 lactose 3 ETS 3 Apomorphine 3 CoCl2 3 Clonidine 3 more...

Enzyme guanylate cyclase 8497 protein kinase 911 NO synthase 879 phosphodiesterase 774 adenylate cyclase 482 PKG 453 NOS 257 protein kinase C 214 superoxide dismutase 182 cGMP phosphodiesterase 176 mitogen-activated protein kinase 165 ATPase 156 heme oxygenase 126 phospholipase C 123 catalase 119 PDE 117 thrombin 81 renin 81 lipoxygenase 67 NADPH-diaphorase 65 ERK 54 phospholipase A2 53 AMPK 52 CD10 51 calcineurin 37 xanthine oxidase 33 tyrosine hydroxylase 32 MEK 31 ACE 30 NADPH oxidase 29 peroxidase 28 luciferase 27 trypsin 27 caspase-3 26 NADPH oxidase 24 CPT 21 CPT 21 CPT 21 rhodopsin kinase 21 reverse transcriptase 20 AMP-activated protein kinase 19 focal adhesion kinase 18 diaphorase 17 lactate dehydrogenase 17 phosphatidylinositol 3-kinase 16 alkaline phosphatase 16 glutathione S-transferase 15 cytochrome oxidase 14 NQO1 14 CaMKII 14 chymotrypsin 14 protein phosphatase 2A 13 myosin light chain kinase 13 RNase 13 diaphorase 13 RNase 13 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 collagenase 12 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 RNA polymerase 11 glutathione peroxidase 11 5'-nucleotidase 11 ACS 11 complex I 10 acetylcholinesterase 10 creatine kinase 10 PAH 9 MAP 9 AMPK 8 GSK 8 tyrosinase 8 carbonic anhydrase 7 PARP 7 lipase 7 GCA 7 arginase 7 proteasome 7 more...

Compound cGMP 4328 nitric oxide 3616 arginine 1573 sodium 1387 calcium 1340 GMP 831 cAMP 669 Dec 628 ATP 556 oxygen 385 AMP 350 GTP 348 potassium 329 CO2 276 Clin 243 Methylene blue 241 water 230 cysteine 228 nitrate 203 glutamate 196 8-Br-cGMP 187 salt 186 DNA 170 manganese 167 glucose 150 ADP 147 iron 139 noradrenaline 137 prostacyclin 132 ADP 132 ADP 130 acetate 116 Mg2+ 115 hydrogen 114 Cardiol 113 ACh 113 tyrosine 112 adenylate 106 phosphate 105 His 101 NMDA 98 nitrogen 97 BNP 88 aldosterone 81 H2O2 78 NADPH 77 NADPH 77 bromide 72 leucine 69 serine 69 alanine 67 Phe 66 hydroxylamine 65 DEA 64 DEA 64 DEA 64 threonine 64 TEA 63 TEA 63 hydroxylamine 62 Heme 61 sulfate 61 Triton X-100 60 zinc 58 5-HT 56 COS 51 PGE2 49 Sildenafil 48 lysine 47 ethanol 46 Nitroglycerin 46 N-acetylcysteine 45 GABA 44 GABA 44 DETA 42 Off 42 NH2 40 caffeine 39 GSH 39 Bradykinin 39 more...

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