Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.6.1.2 (
guanylate cyclase
)
8,497
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
guanylate cyclase
0.726
guanylyl cyclase
0.268
Guanylate cyclase
0.014
NPR-A
0.012
nitric oxide synthase
0.010
PKG
0.010
guanylin
0.009
NPR-B
0.009
C-type natriuretic peptide
0.008
GUCY2D
0.008
GCAP1
0.007
uroguanylin
0.006
GCAP2
0.006
soluble guanylyl cyclase
0.005
ROS-GC1
0.005
atrial natriuretic factor
0.004
GCAP
0.004
atrial natriuretic peptide
0.004
phosphodiesterase
0.004
natriuretic peptide
0.003
Guanylyl cyclase
0.003
cGMP phosphodiesterase
0.003
NPR-C
0.003
SIN
0.003
ANP
0.002
natriuretic peptide receptor A
0.001
adenylate cyclase
0.001
heat-stable enterotoxin receptor
0.001
CNP
0.001
ANF
0.001
GC-E
0.001
natriuretic peptide receptor B
0.001
recoverin
0.001
guanylyl cyclase C
0.001
guanylate cyclase activating protein
0.001
GC1
0.001
PDE5
0.001
GC-F
0.001
GUCA1A
0.001
cGMP-phosphodiesterase activity
0.001
more...
Disease
NAME
0.004
PDE
0.000
Chronic idiopathic constipation
0.000
pulmonary hypertension
0.000
CORD5
0.000
CHEST
0.000
COD3
0.000
difficile; Clostridium
0.000
relaxation; bladder
0.000
hypertension
0.000
CORD6
0.000
LCA12
0.000
LCA
0.000
Cone dystrophy
0.000
erectile dysfunction
0.000
Pulmonary arterial hypertension
0.000
Congenital sodium diarrhea
0.000
Macular dystrophy
0.000
pertussis
0.000
Multiple carboxylase deficiency
0.000
Central areolar choroidal dystrophy
0.000
PAPA
0.000
Hereditary retinal dystrophies
0.000
irritable bowel syndrome
0.000
persistent pulmonary hypertension of the newborn
0.000
heart failure
0.000
Retinal degeneration
0.000
dual personality
0.000
Unilateral renal artery stenosis
0.000
ischemia
0.000
right heart failure
0.000
congestive heart failure
0.000
Biotin deficiency
0.000
AGS3
0.000
neuroblastoma
0.000
Endothelial dysfunction
0.000
ventricular hypertrophy
0.000
renin-dependent hypertension
0.000
NINA
0.000
Persistent pulmonary hypertension
0.000
more...
Symptom
Simple constipation
0.000
constipation
0.000
diarrhea
0.000
chronic constipation
0.000
Functional abdominal pain
0.000
bloating
0.000
Functional constipation
0.000
angina
0.000
hyperoxia
0.000
pain
0.000
analgesia
0.000
Lower urinary tract symptoms
0.000
spasm
0.000
Anoxia
0.000
clonus
0.000
bladder pain
0.000
hypercapnia
0.000
despair
0.000
orofacial pain
0.000
acute pain
0.000
loss of balance
0.000
HSA
0.000
abdominal pain
0.000
hyperesthesia
0.000
abdominal cramps
0.000
Gastrointestinal symptoms
0.000
colic
0.000
seizures
0.000
anesthesia
0.000
exertional dyspnea
0.000
hypothermia
0.000
general problem
0.000
respiratory distress
0.000
headache
0.000
flushing
0.000
microbial colonization
0.000
functional recovery
0.000
urinary frequency
0.000
nasal congestion
0.000
polyuria
0.000
more...
Drug
Methylene blue
0.004
Sodium nitroprusside
0.003
nitroglycerin
0.001
Nitric Oxide
0.000
Nipradilol
0.000
Heme
0.000
Carperitide
0.000
N-Hydroxyguanidine
0.000
7-Nitroindazole
0.000
Viagra
0.000
Viagra
0.000
Leminoprazole
0.000
Molsidomine
0.000
Cicletanine
0.000
Forskolin
0.000
Quinaprilat
0.000
Avanafil
0.000
Equilin
0.000
Angiotensin II
0.000
Pentaerythritol tetranitrate
0.000
Indomethacin
0.000
L-Homoarginine
0.000
Nebivolol
0.000
Cardiovasc
0.000
Nesiritide
0.000
CaCl2
0.000
BH4
0.000
CaCl2
0.000
CaCl2
0.000
ETA
0.000
Gly-Tyr-Gly
0.000
Regitine
0.000
Aminoguanidine
0.000
ICI
0.000
Atropine
0.000
caffeine
0.000
Histamine
0.000
Ergometrine
0.000
PBZ
0.000
Iloprost
0.000
more...
Enzyme
guanylate cyclase
1.000
PKG
0.010
NO synthase
0.006
cGMP phosphodiesterase
0.004
phosphodiesterase
0.004
adenylate cyclase
0.001
protein kinase
0.001
NOS
0.001
heme oxygenase
0.000
PDE
0.000
EC 1.13.11.49
0.000
rhodopsin kinase
0.000
NADPH-diaphorase
0.000
protein kinase C
0.000
phospholipase C
0.000
isoflavone 7-O-glucosyltransferase
0.000
superoxide dismutase
0.000
lipoxygenase
0.000
2-hydroxyisoflavanone dehydratase
0.000
ATPase
0.000
cytidylate cyclase
0.000
mitogen-activated protein kinase
0.000
CD10
0.000
catalase
0.000
retinol isomerase
0.000
AMPK
0.000
2-hydroxyisoflavanone synthase
0.000
phospholipase A2
0.000
thrombin
0.000
lecithin-retinol acyltransferase
0.000
renin
0.000
EC 5.3.3.2
0.000
steroid 11beta-hydroxylase
0.000
CPT
0.000
CPT
0.000
xanthine oxidase
0.000
biliverdin reductase
0.000
SNO
0.000
CPT
0.000
GCA
0.000
more...
Compound
cGMP
0.105
nitric oxide
0.016
GMP
0.009
8-Br-cGMP
0.006
Methylene blue
0.004
arginine
0.003
cAMP
0.001
sodium
0.001
calcium
0.001
DEA
0.001
DEA
0.001
DEA
0.001
BNP
0.000
GTP
0.000
NPR
0.000
DETA
0.000
AMP
0.000
Nitroprusside
0.000
ATP
0.000
Nitro-L-arginine
0.000
Sildenafil
0.000
Nicorandil
0.000
Nitroglycerin
0.000
adenylate
0.000
TEA
0.000
TEA
0.000
ACh
0.000
D-NONOate
0.000
5-Nitroisatin
0.000
Vindorosine
0.000
prostacyclin
0.000
potassium
0.000
Isatin
0.000
Heme
0.000
Tetrahydroneopterin
0.000
8-iso-PGF2beta
0.000
CO2
0.000
8-iso-PGE1
0.000
manganese
0.000
nitrate
0.000
more...