Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:4.6.1.2 (guanylate cyclase)
8,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein guanylate cyclase 6167 guanylyl cyclase 2279 nitric oxide synthase 1585 phosphodiesterase 772 ATP 556 Sep 554 Mol 531 atrial natriuretic peptide 478 natriuretic peptide 474 adenylate cyclase 471 PKG 453 atrial natriuretic factor 391 GTP 345 AMP 309 soluble guanylyl cyclase 282 C-type natriuretic peptide 273 cyclooxygenase 242 calmodulin 235 NPR-A 230 adenylyl cyclase 194 SIN 193 membrane-bound 190 hemoglobin 190 NPR-B 183 ANP 180 bradykinin 173 superoxide dismutase 168 Guanylate cyclase 161 guanylin 157 neuronal nitric oxide synthase 156 angiotensin II 147 ATPase 146 heme oxygenase-1 138 inducible nitric oxide synthase 133 cGMP phosphodiesterase 133 lipopolysaccharide 131 ADP 130 insulin 123 SNAP 123 catalase 118 more...

Disease NAME 646 hypertension 436 pulmonary hypertension 190 heart failure 139 ischemia 138 diabetes 113 cancer 94 pertussis 93 tumor 87 depression 85 PDE 79 atherosclerosis 78 erectile dysfunction 73 stroke 62 congestive heart failure 59 cardiovascular disease 58 neuroblastoma 58 sepsis 47 irritable bowel syndrome 47 sepsis 46 LCA 43 myocardial infarction 41 cholera 41 obesity 38 asthma 37 GSH 36 myocardial ischemia 36 ventricular hypertrophy 34 SDS 32 blindness 32 Pulmonary arterial hypertension 32 Alzheimer's disease 29 vascular disease 29 glioma 24 heart disease 23 uterus 23 coronary artery disease 23 right heart failure 23 cirrhosis 23 SEM 23 more...

Symptom diarrhea 93 pain 90 constipation 49 angina 35 analgesia 24 anesthesia 22 seizures 19 abdominal pain 15 headache 14 hyperoxia 13 chronic constipation 13 spasm 11 bloating 10 hypercapnia 8 respiratory distress 8 hypothermia 8 starvation 7 discomfort 6 collapse 6 discomfort 6 functional recovery 6 erythema 5 acute pain 5 ataxia 5 dyspnea 4 flushing 4 chest pain 4 HSA 4 despair 3 colic 3 exertional dyspnea 3 dystonia 2 polyuria 2 weakness 2 fatigue 2 Anoxia 2 clonus 2 nausea 2 orofacial pain 2 acidity 2 more...

Drug nitroglycerin 221 Methylene blue 216 Sodium nitroprusside 160 Cardiovasc 157 Nitric Oxide 81 Heme 60 caffeine 39 ascorbate 36 ROS 32 lysine 31 Indomethacin 30 Angiotensin II 29 CaCl2 26 CaCl2 25 CaCl2 25 Forskolin 24 Nephron 22 NADH 20 Asn 20 ICI 20 Histamine 19 Ethanol 17 ETA 16 Gel 15 MAP 15 Atropine 15 Viagra 15 Viagra 13 Dermatol 12 BH4 12 CTX 11 CSF 10 IL-2 10 vitamin E 10 IFN-gamma 9 Ouabain 9 Nipradilol 8 FAD 7 PTH 7 7-Nitroindazole 6 more...

Enzyme guanylate cyclase 8497 protein kinase 911 NO synthase 879 phosphodiesterase 774 adenylate cyclase 482 PKG 453 NOS 257 protein kinase C 214 superoxide dismutase 182 cGMP phosphodiesterase 176 mitogen-activated protein kinase 165 ATPase 156 heme oxygenase 126 phospholipase C 123 catalase 119 PDE 117 thrombin 81 renin 81 lipoxygenase 67 NADPH-diaphorase 65 ERK 54 phospholipase A2 53 AMPK 52 CD10 51 calcineurin 37 xanthine oxidase 33 tyrosine hydroxylase 32 MEK 31 ACE 30 NADPH oxidase 29 peroxidase 28 trypsin 27 luciferase 27 caspase-3 26 NADPH oxidase 24 CPT 21 CPT 21 CPT 21 rhodopsin kinase 21 reverse transcriptase 20 more...

Compound cGMP 4328 nitric oxide 3616 arginine 1573 sodium 1387 calcium 1340 GMP 831 cAMP 669 Dec 628 ATP 556 oxygen 385 AMP 350 GTP 348 potassium 329 CO2 276 Clin 243 Methylene blue 241 water 230 cysteine 228 nitrate 203 glutamate 196 8-Br-cGMP 187 salt 186 DNA 170 manganese 167 glucose 150 ADP 147 iron 139 noradrenaline 137 prostacyclin 132 ADP 132 ADP 130 acetate 116 Mg2+ 115 hydrogen 114 Cardiol 113 ACh 113 tyrosine 112 adenylate 106 phosphate 105 His 101 more...

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