Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.6.1.2 (guanylate cyclase)
 8,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
GUANYLATE CYCLASE 11.9
prostaglandin I2 (prostacyclin) receptor 11.9
guanylyl cyclase 11.9
COD3 11.9
guanylate cyclase 11.9
guanylate cyclase-activating protein 2 11.9
guanylate cyclase 1, soluble, beta 3 11.9
heat-stable enterotoxin receptor 11.7
GCAP2 11.6
GCAP3 11.5
Guanylate cyclase 11.4
GCAP1 11.3
GUCA1B 11.3
CORD5 11.3
GCAP 11.2
GUCY2D 11.2
ROS-GC1 11.1
retinal degeneration 3 11.1
GC-E 11.0
guanylate cyclase activating protein 10.9
G-protein-coupled receptor kinase 1 10.9
PRKG1 protein 10.9
PDZD3 10.9
SOX25 10.9
guanylin 10.8
GUCA1A 10.8
cGMP-phosphodiesterase activity 10.7
NPR-A 10.7
uroguanylin 10.7
Guanylyl cyclase 10.6
NPR-B 10.6
GC-F 10.5
GUCY1B3 10.5
cGMP-stimulated phosphodiesterase 2 10.3
natriuretic peptide clearance receptor 10.3
GPSM4 10.3
natriuretic peptide receptor A 10.2
natriuretic peptide receptor B 10.2
NPR-C 10.1
GCA1 9.9
regulator of G-protein signalling 9 9.9
F-box domain protein 9.9
HKB3 9.9
D2LIC 9.9
C-type natriuretic peptide 9.8
GUCY1A3 9.8
neurocalcin delta 9.6
neurocalcin 9.6
MAP kinase phosphatase 5 9.6
PDZ domain-containing protein 2 9.6
GKAP42 9.6
PKG1 9.6
cGMP phosphodiesterase 9.4
PKG 9.4
GC1 9.4
CHL1 protein 9.3
guanylyl cyclase C 9.2
GUCY2C 9.2
soluble guanylyl cyclase 9.2
Nucleoside diphosphokinase 9.1
cGKI 8.9
FIN13 8.9
PDE1B1 8.9
recoverin 8.8
CNP 8.8
PTCHD3 8.7
RAB28 8.7
SIN 8.7
NPR 8.6
Cocaine-and amphetamine-regulated transcript 8.6
CaM-PDE 8.6
rab28 8.6
ANF 8.5
EDRF 8.5
atrial natriuretic factor 8.5
ZIN 8.4
3',5'-cyclic-nucleotide phosphodiesterase 8.4
ANP 8.4
RD3 8.3
PDE5 8.3
phosphodiesterase 5A 8.3
Visinin-like protein 1 8.3
32 AA 8.3
VILIP-3 8.3
Bradykinin B1 receptor 8.3
G protein-coupled receptor kinase 1 8.3
HFH-3 8.3
CNGA3 8.2
kinesin 2 8.2
GC2 8.1
cGMP-PDE 8.1
atrial natriuretic peptide 8.1
STK16 8.1
Constitutive NOS 8.1
HKR1 8.1
Nostrin 8.1
VILIP-1 8.1
EBR1 8.1
PP2Cm 8.0
PDE2A 8.0
RAP1GAP 8.0
sulfonylurea receptor 2 8.0
NCS-1 8.0
cGKII 7.9
transient receptor potential channel 3 7.9
PDE1B 7.8
PDE2 7.8
natriuretic peptide 7.8
rhodopsin kinase 7.8
vasodilator-stimulated phosphoprotein 7.8
neuropilin 2 7.7
HO-2 7.7
NOC 7.7
PDE5A 7.7
voltage-dependent anion channel 3 7.7
CNGA1 7.7
nitric oxide synthase 7.6
QIL1 7.6
small-conductance calcium-activated potassium channel 7.6
CNGB1 7.6
cGMP-gated cation channel 7.6
aryl hydrocarbon receptor-interacting protein-like 1 7.6
BNP 7.5
Hippocalcin 7.5
MPP3 7.5
smoothelin-like 1 7.5
ASJ 7.4
PAPA 7.4
GJA4 7.4
ADCY3 7.3
IFT122 7.3
phosphodiesterase 7.3
PDE1A 7.3
sperm acrosomal protein 7.3
PDE9A 7.2
BX1 7.2
ponsin 7.2
SLC9A3 7.2
UROD 7.2
G-substrate 7.2
NOR-1 7.1
p25 protein 7.1
Kir2.4 7.1
PDE1C 7.0
GDN 7.0
TYRP2 7.0
Rhodopsin kinase 7.0
C128 7.0
IFT57 7.0
musclin 7.0
neuronal nitric oxide synthase 7.0
constitutive nitric oxide synthase 7.0
PDE 7.0
type I transmembrane receptor 7.0
hippocalcin 6.9
STII 6.9
RGS9 6.9
SNAP 6.9
IFT80 6.9
PCP2 6.9
FXYD2 6.9
RNO 6.9
adenosine monophosphate deaminase 6.9
calcium-activated potassium channel 6.9
Activator of G-protein signaling 3 6.9
IFT140 6.9
CDC50A 6.9
densin-180 6.9
sodium-dependent glucose transporter 1 6.9
GPSM2 6.9
C4BPA 6.8
AGS3 6.8
NOS-1 6.8
CYP2B protein 6.8
NDEL1 6.8
GRK1 6.8
NOS1 6.8
RPR1 6.8
GC kinase 6.8
OLF 6.7
R9AP 6.7
ADCY9 6.7
TRIB2 6.7
CNP1 6.7
RGSZ1 6.7
cyclic nucleotide phosphodiesterase 6.7
Phosphodiesterase 6.7
myosin phosphatase target subunit 1 6.7
muskelin 6.7
ankyrin repeat-containing protein 6.7
NOS3 6.7
small conductance calcium-activated potassium channel 6.6
Adenylyl cyclase 6.6
adenylate cyclase 6.6
NOR1 6.6
MKP-5 6.6
HTGL 6.6
retina-specific 6.6
transducin alpha 6.6
cAMP-specific phosphodiesterase 6.6
ATP pyrophosphate-lyase 6.6
eNOS 6.6
GMPS 6.6
PDE3B 6.5
EFS 6.5
CNGA2 6.5
AQR 6.5
TAG-1 6.5
Endothelin-3 6.5
holocarboxylase synthetase 6.5
ASIC4 6.5
RIC-8 6.4
putative G protein-coupled receptor 6.4
nitric oxide synthase 1 6.4
SCR2 6.4
NOS III 6.4
calmodulin-dependent phosphodiesterase 6.4
Cyclin-dependent kinase inhibitor 6.4
adenylyl cyclase 6.4
endothelial nitric oxide synthase 6.4
sodium/glucose cotransporter 2 6.3
ileal bile acid transporter 6.3
6-pyruvoyl-tetrahydropterin synthase 6.3
clone 22 6.3
Cyclic nucleotide phosphodiesterase 6.3
guanine nucleotide regulatory protein 6.3
VIP36 6.3
soluble adenylyl cyclase 6.3
phosphoinositide phospholipase C 6.3
DD5 6.3
6-pyruvoyltetrahydropterin synthase 6.3
SIN1 6.2
Ras inhibitor 6.2
sodium-dependent multivitamin transporter 6.2
Bro 6.2
GMP synthase 6.2
myosin RLC 6.2
ANGPT2 6.2
HAGE 6.2
cytochrome P450 epoxygenase 6.2
NEDD4-1 6.1
lyt-10 6.1
OTX1 6.1
receptor activity-modifying protein 1 6.1
GMP 6.1
Endothelial nitric oxide synthase 6.1
RAP1B 6.1
RDH5 6.1
prepronociceptin 6.1
BAG 6.1
polycystin 2 6.1
ARRB2 6.1
LBH 6.0
5-HT5A 6.0
diglyceride kinase 6.0
platelet phospholipase A2 6.0
CATSPER 6.0
NONO 6.0
NCKX2 6.0
endothelin receptor 6.0
HO2 6.0
TRAM 6.0
NDUFS1 6.0
Cullin-3 5.9
staufen 5.9
KCP 5.9
PDE4C 5.9
GM-CSF receptor 5.9
SNO 5.9
heme oxygenase-1 5.9
CgA 5.9
DAF 5.9
cyclic AMP phosphodiesterase 5.9
prostaglandin I2 5.9
LMX1A 5.8
Gbeta5 5.8
DDAH-1 5.8
sperm receptor 5.8
EF-2 5.8
corin 5.8
coenzyme A synthase 5.8
PRKG1 5.8
RBP2 5.8
AHA1 5.8
GPR14 5.8
ADH5 5.8
G protein-coupled receptor kinase 4 5.8
TRIM 5.8
G2A 5.8
Cystic fibrosis transmembrane conductance regulator 5.8
H4B 5.8
Neutral endopeptidase 5.8
RGS10 5.8
Serotonin receptor 5.8
Cav2.2 5.8
GC-1 5.8
IFT88 5.8
G mRNA 5.7
protein-tyrosine-phosphatase 5.7
HO-1 5.7
PT1 5.7
inducible form 5.7
B22 5.7
Kv3.2 5.7
biliverdin reductase 5.7
VASP 5.7
espin 5.7
ribosomal protein S13 5.7
phosphodiesterase 3B 5.7
cyclooxygenase 5.7
NPPA 5.7
receptor protein kinase 5.7
KChIP1 5.7
SMMHC 5.7
DG2 5.7
CtBP2 5.7
NHE4 5.6
Rhotekin 5.6
NP3 5.6
S100beta 5.6
more...
Disease
difficile; Clostridium 11.9
relaxation; bladder 11.9
COD3 11.9
CORD5 11.3
LCA12 10.9
CORD6 10.1
Chronic idiopathic constipation 10.0
Congenital sodium diarrhea 9.9
Cone dystrophy 9.7
Macular dystrophy 9.3
Multiple carboxylase deficiency 9.1
CHEST 8.9
Central areolar choroidal dystrophy 8.9
Hereditary retinal dystrophies 8.4
dual personality 8.2
Unilateral renal artery stenosis 8.2
NAME 7.5
PAPA 7.2
Biotin deficiency 6.9
PDE 6.9
AGS3 6.8
Retinal degeneration 6.8
NINA 6.6
Persistent pulmonary hypertension 6.5
Flashing 6.4
renin-dependent hypertension 6.4
Pulmonary arterial hypertension 6.4
LCA 6.3
persistent pulmonary hypertension of the newborn 6.2
Pineal gland 5.9
Pineal gland 5.9
Pineal gland 5.9
Myometrium 5.9
cholestatic cirrhosis 5.8
vascular dilation 5.7
RAT 5.6
hypotension and shock 5.4
E. coli septicemia 5.4
Postoperative ileus 5.3
hypertensive cardiomyopathy 5.3
erectile dysfunction 5.3
Portopulmonary hypertension 5.3
pulmonary hypertension 5.3
orphan disease 5.2
Purging 5.2
SFD 5.1
cardiac overload 5.1
retinal vascular occlusion 5.1
Traveler's diarrhea 4.9
Endothelial dysfunction 4.8
Trachea 4.8
Trachea 4.8
Trachea 4.7
Recessive dystrophic epidermolysis bullosa 4.7
Ureteral obstruction 4.6
Diabetes and Pregnancy 4.6
ISD 4.6
right heart failure 4.5
CHH 4.5
irritable bowel syndrome 4.5
achromatopsia 4.4
Chronic heart failure 4.4
Primary open-angle glaucoma 4.3
Tension 4.3
adrenocortical carcinoma 4.3
SMC 4.3
Malassez 4.3
Waardenburg syndrome 4.2
achondroplasia 4.2
pertussis 4.2
HTX 4.1
TNS 4.1
HTX 4.1
Endometrium 4.0
Endometrium 4.0
fluid overload 4.0
leprechaunism 4.0
gastroparesis 4.0
Functional dyspepsia 4.0
cerebral vasospasm 4.0
cycloplegia 4.0
HMR 3.9
premature ejaculation 3.9
visual dysfunction 3.8
gastric lesion 3.8
HBD 3.8
priapism 3.8
hypertensive heart disease 3.8
endotoxic shock 3.7
PRS 3.7
vascular obstruction 3.7
disabling disease 3.7
SIRS 3.7
Parainfluenza 3.7
Bateman 3.6
hepatic encephalopathy 3.6
Ullrich 3.6
hypertensive nephropathy 3.6
ICS 3.6
chronic ischemic heart disease 3.5
Nystagmus 3.5
Goldblatt 3.5
ventricular hypertrophy 3.5
aqueous humor 3.5
Tic 3.4
MLC 3.4
Luminal 3.4
HTL 3.4
Liver regeneration 3.4
Diabetic neuropathy 3.4
methemoglobinemia 3.3
SPM 3.3
chronic leukemia 3.3
hypertension 3.3
Hyperplasia 3.3
PDC 3.2
Bronchiolitis obliterans 3.2
Renal fibrosis 3.2
Lowe 3.2
Bernard-Soulier syndrome 3.2
Neuromuscular blockade 3.2
congestive heart failure 3.2
hypernatremia 3.2
Bezold 3.2
amaurosis 3.2
bacillary dysentery 3.1
retinitis pigmentosa 3.1
antidiuresis 3.1
Frey 3.1
esophageal dysmotility 3.1
Hypertrophic 3.1
HCI 3.1
vaginal infection 3.1
CHR 3.1
renal hypertension 3.0
CSE 3.0
giant cell arteritis 3.0
arteriopathy 3.0
neuroblastoma 3.0
LMS 2.9
LMS 2.9
PTP 2.9
cholera 2.9
PAF 2.9
blindness 2.9
nephrosis 2.9
Spencer 2.9
heart failure 2.9
gastrointestinal disease 2.8
Blocking 2.8
hyperopia 2.8
TEC 2.8
diabetic cardiomyopathy 2.8
hepatic coma 2.8
idiopathic thrombocytopenic purpura 2.7
Cirrhosis 2.7
achalasia 2.7
ocular hypertension 2.7
localized scleroderma 2.7
acute diarrhea 2.7
left ventricular failure 2.7
acute chest syndrome 2.7
ICC 2.7
choreoathetosis 2.7
vascular disease 2.7
HPP 2.7
ICC 2.7
secondary hypertension 2.6
Ductal 2.6
paralytic ileus 2.6
PLG 2.6
kidney tumor 2.6
impotence 2.6
LTD 2.6
testicular feminization 2.6
urethra 2.6
fetal hypoxia 2.6
KNO 2.6
Kearns-Sayre syndrome 2.6
anemia of chronic disease 2.5
genetic hypertension 2.5
mixed connective tissue disease 2.5
Pineal 2.5
ischemia 2.5
pheochromocytoma 2.5
LIN 2.5
open angle glaucoma 2.5
ATM 2.5
chemical carcinogenesis 2.4
PDD 2.4
hypercholesterolemia 2.4
Thoracic 2.4
EMD 2.4
ADCC 2.3
PSS 2.3
PSS 2.3
Congenital heart disease 2.3
portal hypertension 2.3
intraocular pressure 2.3
PSS 2.3
roundworm 2.3
unstable angina 2.2
adult respiratory distress syndrome 2.2
anaphylaxis 2.2
Peyronie's disease 2.2
dyspepsia 2.2
bronchopulmonary dysplasia 2.2
Harada 2.2
Lesch-Nyhan syndrome 2.2
ileitis 2.2
MSA 2.2
Bardet-Biedl syndrome 2.1
EDC 2.1
myocardial ischemia 2.1
MDI 2.1
Buerger's disease 2.1
acute intermittent porphyria 2.1
PSP 2.1
retinopathy 2.1
FBS 2.1
Machado-Joseph disease 2.1
second cancer 2.1
hyperosmolality 2.1
sickle cell disease 2.1
RGS 2.1
insulinoma 2.0
coronary occlusion 2.0
nephrogenic diabetes insipidus 2.0
night blindness 2.0
ischemic colitis 2.0
HCA 2.0
dysautonomia 2.0
PNS 2.0
EIA 2.0
LMS 2.0
NBS 2.0
FFM 2.0
Rhabdomyosarcoma 2.0
CAA 1.9
subarachnoid hemorrhage 1.9
atherosclerosis 1.9
prediabetes 1.9
Li-Fraumeni syndrome 1.9
mountain sickness 1.9
astrocytoma 1.9
intellectual impairment 1.9
lymphatic vessels 1.9
moyamoya 1.9
renal impairment 1.9
tetanus 1.8
chondrodysplasia 1.8
LBD 1.8
sexual dysfunction 1.8
GSH 1.8
pseudomembranous colitis 1.8
Yersinia 1.8
diabetic nephropathy 1.8
Posterior 1.8
filariasis 1.8
EPI 1.8
organic disease 1.8
ileus 1.8
Staphylococcus aureus infection 1.8
LDLR 1.8
ADH 1.7
vitreous humor 1.7
fear and anxiety 1.7
PDS 1.7
cardiovascular disease 1.7
sepsis 1.7
alkalosis 1.7
SCD 1.7
cerebral aneurysm 1.7
PPP 1.7
nerve lesion 1.7
Adhesion 1.7
CCD 1.7
interstitial lung disease 1.6
LAP 1.6
CHS 1.6
thiamine deficiency 1.6
erythrocytosis 1.6
tubular necrosis 1.6
connective tissue disease 1.6
CCD 1.6
SCH 1.6
sepsis 1.6
tardive dyskinesia 1.6
sinus tachycardia 1.6
Cushing's disease 1.5
toxemia 1.5
glioma 1.5
interstitial cystitis 1.5
carcinoid syndrome 1.5
PIN 1.5
CAA 1.5
cystic fibrosis 1.5
agranulocytosis 1.5
Merkel cell carcinoma 1.5
MTS 1.5
Evans 1.5
liver fibrosis 1.4
ureter 1.4
idiopathic pulmonary fibrosis 1.4
lactic acidosis 1.4
peripheral vascular disease 1.4
DSS 1.4
scleroderma 1.4
mimicry 1.4
preeclampsia 1.4
enteropathy 1.4
essential hypertension 1.4
uterus 1.3
heart disease 1.3
PCC 1.3
acute myocardial infarction 1.3
respiratory acidosis 1.3
glomerulosclerosis 1.3
CTX 1.3
brain edema 1.3
more...
Symptom
Simple constipation 11.9
Functional abdominal pain 6.4
Functional constipation 6.0
chronic constipation 5.2
bloating 4.5
Lower urinary tract symptoms 4.3
constipation 4.2
Anoxia 3.8
clonus 3.3
bladder pain 3.3
hyperoxia 3.2
loss of balance 3.1
orofacial pain 3.0
hyperesthesia 2.8
abdominal cramps 2.8
despair 2.8
Gastrointestinal symptoms 2.7
angina 2.6
diarrhea 2.6
spasm 2.5
HSA 2.3
acute pain 2.2
general problem 2.1
hypercapnia 1.9
microbial colonization 1.8
colic 1.8
urinary frequency 1.7
exertional dyspnea 1.7
nasal congestion 1.7
analgesia 1.7
skin damage 1.3
polyuria 1.3
photophobia 1.2
flushing 1.2
hypocapnia 1.1
abdominal discomfort 1.1
abdominal pain 0.9
hypothermia 0.8
tense 0.8
polydipsia 0.8
functional recovery 0.7
bradykinesia 0.7
respiratory distress 0.6
erythema 0.5
pain 0.4
hemoptysis 0.3
ataxia 0.2
epigastric pain 0.1
starvation 0.1
memory loss 0.1
discomfort 0.0
headache -0.1
pelvic pain -0.1
discomfort -0.1
dystonia -0.2
seizures -0.2
chest pain -0.2
acute stress -0.3
collapse -0.3
wheezing -0.4
anesthesia -0.4
ENT -0.5
hunger -0.6
myalgia -0.8
tinnitus -0.8
dyspnea -0.9
vertigo -0.9
arthralgia -0.9
acidity -1.0
tremor -1.3
syncope -1.3
dizziness -1.4
splenomegaly -1.4
thinning -1.6
nausea -1.6
agitation -1.7
back pain -1.7
stigma -1.8
anorexia -1.9
weakness -2.3
cough -2.7
fatigue -2.8
vomiting -3.1
Drug
N-Hydroxyguanidine 10.3
Carperitide 9.6
Methylene blue 9.3
Sodium nitroprusside 9.3
Nipradilol 8.9
Leminoprazole 8.9
7-Nitroindazole 8.0
Quinaprilat 7.8
Avanafil 7.7
Equilin 7.6
Cicletanine 7.5
Pentaerythritol tetranitrate 7.3
Molsidomine 7.2
L-Homoarginine 7.2
Nitric Oxide 6.9
Viagra 6.7
Viagra 6.6
nitroglycerin 6.5
Regitine 6.5
Gly-Tyr-Gly 6.5
Nesiritide 6.5
Heme 6.2
Nebivolol 6.1
PBZ 6.1
Ergometrine 6.1
Ibudilast 6.0
Batroxobin 5.9
Tegaserod 5.7
Omapatrilat 5.7
Ramelteon 5.6
Ferrous sulfate 5.6
Aminoguanidine 5.5
Timolol maleate 5.4
Tegaserod 5.4
Treprostinil 5.4
Vardenafil 5.4
Quisqualate 5.4
Malonaldehyde 5.2
Glybenclamide 5.2
Iloprost 5.1
Rolipram 5.1
Forskolin 5.1
Phosphoramidon 5.1
Trifluoperazine 5.1
Red ginseng 5.0
BH4 4.9
Vinpocetine 4.7
Trental 4.6
Lead acetate 4.6
Guanidine 4.5
Guanidine 4.5
Dronedarone 4.5
ETA 4.4
Angiotensin II 4.4
Salmon calcitonin 4.4
Dihydroergotamine 4.3
Carbenoxolone 4.3
Tranilast 4.2
Bumetanide 4.2
Thiopentone 4.2
Indomethacin 4.2
Atropine 4.1
Calcium chloride 4.1
Emodin 4.0
Tubocurarine 3.9
Escitalopram 3.9
CaCl2 3.9
CaCl2 3.9
CaCl2 3.9
Luteinizing 3.8
Zmax 3.8
ICI 3.8
KCL 3.8
Guanethidine 3.8
Ouabain 3.7
Atenolol 3.7
Bestatin 3.7
Emodin 3.7
Histamine 3.7
Phentolamine 3.7
Nimesulide 3.6
Amiloride 3.6
Myricetin 3.6
Exenatide 3.6
Kainic acid 3.5
EDR 3.5
Rimonabant 3.5
Gemfibrozil 3.5
Salbutamol 3.4
FeCl3 3.4
Vorinostat 3.4
Amiloride 3.4
CIA 3.3
Bayer 3.2
Theophylline 3.2
Apomorphine 3.2
CoCl2 3.2
CoCl2 3.2
Fraction 3.1
Pronase 3.1
Adenosine triphosphate 3.1
AHF 3.0
Papaverine 3.0
Valsartan 3.0
Monensin 3.0
Glutamic acid 2.9
NAG 2.8
caffeine 2.8
Estrogens 2.7
GHRP 2.7
Ethanol 2.7
Asn 2.7
ROS 2.6
Dasatinib 2.6
Vitamin B 2.6
Cremophor EL 2.6
ascorbate 2.5
ZnCl2 2.5
ZnCl2 2.5
Rutin 2.5
-deoxyadenosine 2.4
Ringer's solution 2.4
Raloxifene 2.4
Secretin 2.4
balanced salt solution 2.3
MgSO4 2.3
Bupivacaine 2.3
FAD 2.2
Clonidine 2.2
Cimetidine 2.2
Nephron 2.2
Pravastatin 2.2
Simvastatin 2.2
Cimetidine 2.2
ETS 2.1
SF6 2.1
Glutathione 2.1
Aprotinin 2.0
Photofrin 2.0
CTX 2.0
Alanine 2.0
Parkin 2.0
Parkin 2.0
ALA 2.0
PTH 1.9
Gel 1.9
Omeprazole 1.9
PFA 1.9
Diphenhydramine 1.8
MAP 1.8
EPI 1.8
DMI 1.8
FLP 1.8
NADH 1.8
Clopidogrel 1.8
Etoposide 1.7
Lactose 1.7
L-tyrosine 1.7
Azithromycin 1.6
PCP 1.6
Cardiovasc 1.6
Arsenic trioxide 1.6
Fentanyl 1.6
Scopolamine 1.5
EE2 1.5
NBT 1.5
IL-1ra 1.5
CTX 1.4
CTX 1.4
Prednisolone 1.3
Ranitidine 1.2
Ginseng 1.2
vitamin E 1.1
TTC 1.0
Glucagon 1.0
niacin 1.0
lysine 1.0
Fructose 1.0
citric acid 0.9
Frontal 0.9
Propofol 0.8
Captopril 0.7
Glycerol 0.7
Fragment 0.7
Adriamycin 0.7
NH3 0.7
pyridoxal phosphate 0.6
Alliance 0.5
IL-2 0.4
Nephron 0.3
IFN-beta 0.3
Vitamin A 0.3
CSF 0.3
IFN-gamma 0.2
Vitamin E 0.2
Kenyan 0.1
Portal -0.2
Albumin -0.4
lactose -0.6
Asthma -0.8
ROC -1.0
DNase I -1.2
ENT -1.2
Monit -1.2
Dial -1.4
Leaf -1.5
Dermatol -2.5
Enzyme
EC 1.13.11.49 11.9
guanylate cyclase 11.9
isoflavone 7-O-glucosyltransferase 9.6
cGMP phosphodiesterase 9.4
PKG 9.4
2-hydroxyisoflavanone dehydratase 9.1
cytidylate cyclase 8.7
retinol isomerase 8.0
2-hydroxyisoflavanone synthase 7.9
NO synthase 7.7
rhodopsin kinase 7.7
lecithin-retinol acyltransferase 7.6
EC 5.3.3.2 7.5
steroid 11beta-hydroxylase 7.5
phosphodiesterase 7.3
NOS 7.0
PDE 6.9
heme oxygenase 6.8
adenylate cyclase 6.6
ecdysone 20-monooxygenase 6.4
protein N-myristoyltransferase 6.3
6-pyruvoyltetrahydropterin synthase 6.3
GMP synthase 6.1
biliverdin reductase 6.1
tyrosylprotein sulfotransferase 6.0
NADPH-diaphorase 6.0
SNO 5.9
carboxypeptidase S 5.7
isoflavone reductase 5.6
protein kinase 5.4
GCA 5.2
lipoxygenase 4.9
lysophosphatidylcholine acyltransferase 4.8
EC 3.6.1.1 4.8
prolinase 4.7
thromboxane synthase 4.7
anthocyanidin synthase 4.7
LipA 4.7
GMP synthetase 4.6
phospholipase C 4.6
CPT 4.6
inosine triphosphatase 4.6
lecithin:retinol acyltransferase 4.5
nucleoside diphosphokinase 4.5
BBE 4.5
GTP cyclohydrolase I 4.5
CPT 4.5
VIP1 4.5
3'-phosphatase 4.5
propionyl-CoA carboxylase 4.5
ADP-ribosyltransferase 4.5
propionyl-CoA carboxylase 4.4
ADP-ribosyltransferase 4.4
clotting enzyme 4.4
sepiapterin reductase 4.4
cytochrome P-450scc 4.3
prostacyclin synthase 4.3
CD10 4.3
N-acetylglucosaminyltransferase I 4.2
cinnamate 4-hydroxylase 4.2
PIP kinase 4.2
myosin light chain kinase 4.2
endoproteinase Glu-C 4.2
diaphorase 4.1
arylamine N-acetyltransferase 4.1
CPT 4.1
CPN 4.1
argininosuccinate synthetase 4.0
protein kinase C 4.0
AMP-activated kinase 4.0
protein phosphatase 2A 4.0
guanase 4.0
eEF2 kinase 4.0
AMPK 4.0
pantothenate kinase 3.9
diacylglycerol kinase 3.9
PTPase 3.9
xanthine oxidase 3.9
SPT 3.8
phospholipase A2 3.8
PI-PLC 3.7
chalcone isomerase 3.7
12-lipoxygenase 3.7
CaMKII 3.7
5'-nucleotidase 3.7
dissimilatory sulfite reductase 3.7
aconitase 3.7
triphosphatase 3.6
nitrite reductase 3.6
phenylethanolamine N-methyltransferase 3.6
hormone-sensitive lipase 3.6
nitrite reductase 3.6
nitrite reductase 3.6
4CL 3.5
superoxide dismutase 3.5
ceramidase 3.5
phosphatidylinositol 4-kinase 3.5
ALA synthase 3.5
FPS 3.4
diaphorase 3.4
oxidosqualene cyclase 3.4
ATP sulfurylase 3.4
guanylate kinase 3.4
endoglycosidase H 3.4
aldehyde dehydrogenase 3.4
aldehyde dehydrogenase 3.4
prostaglandin synthetase 3.3
aldehyde dehydrogenase 3.3
nucleotide pyrophosphatase 3.3
15-lipoxygenase 3.3
cathepsin C 3.3
NADPH oxidase 3.3
N-acetyltransferase 3.3
histidine kinase 3.2
3'-exonuclease 3.2
phospholipase A1 3.2
argininosuccinate lyase 3.2
thrombin 3.2
ATPase 3.2
aminopeptidase A 3.2
4-epimerase 3.1
NAD glycohydrolase 3.1
NADPH oxidase 3.1
aldehyde dehydrogenase 3.1
renin 3.1
NQO1 3.1
phosphorylase kinase 3.1
ALDH 3.1
SPT 3.1
ferrochelatase 3.0
venom phosphodiesterase 3.0
tyrosine hydroxylase 3.0
calcineurin 3.0
catalase 3.0
caspase-6 3.0
PAH 2.9
caspase-6 2.9
calcium pump 2.9
apyrase 2.9
nucleotidase 2.9
cystathionine gamma-lyase 2.8
arginase 2.8
arginine decarboxylase 2.8
aldehyde dehydrogenase 2.8
dehydroascorbate reductase 2.8
ADPase 2.8
GRK5 2.7
mitogen-activated protein kinase 2.7
MEK 2.7
cathepsin G 2.6
lecithin:cholesterol acyltransferase 2.6
ACE 2.6
carboxypeptidase B 2.6
arginine decarboxylase 2.6
MPP 2.6
cytochrome oxidase 2.6
factor C 2.6
endothelin-converting enzyme 2.6
porphobilinogen deaminase 2.6
BAL 2.5
arylalkylamine N-acetyltransferase 2.5
3-hydroxyacyl-CoA dehydrogenase 2.5
3-hydroxyacyl-CoA dehydrogenase 2.5
mu-calpain 2.4
AMP-activated protein kinase 2.4
phosphatidylinositol 3-kinase 2.4
fatty acid desaturase 2.4
purine nucleoside phosphorylase 2.4
gamma-glutamylcysteine synthetase 2.4
aequorin 2.4
deoxyribonuclease 2.3
Mg2+-ATPase 2.3
nitrate reductase 2.3
nitrate reductase 2.3
nitrate reductase 2.3
nitrate reductase 2.3
nitrate reductase 2.3
PNGase F 2.3
deoxyribonuclease 2.3
nitrate reductase 2.3
ascorbate oxidase 2.3
chymotrypsin 2.3
AMPK 2.3
MAP 2.2
methionine synthase 2.2
acyl-CoA synthetase 2.2
GSK 2.1
adenosine deaminase 2.1
GRK2 2.1
adenosine deaminase 2.1
sucrase-isomaltase 2.1
glycerol-3-phosphate dehydrogenase 2.1
complex I 2.1
trehalase 2.1
glucose oxidase 2.1
glycerol-3-phosphate dehydrogenase 2.1
prolyl hydroxylase 2.0
Pla 2.0
IMP dehydrogenase 2.0
methionine synthase 2.0
MEKK1 2.0
3beta-hydroxysteroid dehydrogenase 2.0
C3 convertase 2.0
adenosine kinase 2.0
phospholipase D 2.0
ribonucleotide reductase 2.0
glucokinase 2.0
acetyl-CoA carboxylase 2.0
cystathionine beta-synthase 2.0
ribonucleotide reductase 1.9
glucose-6-phosphatase 1.9
DOPA decarboxylase 1.8
choline acetyltransferase 1.8
carbonic anhydrase 1.8
phosphoglycerate kinase 1.8
proprotein convertase 1.8
ADH 1.7
glyceraldehyde-3-phosphate dehydrogenase 1.7
tyrosinase 1.7
glyceraldehyde-3-phosphate dehydrogenase 1.7
sucrase 1.6
TSA 1.6
arylsulfatase 1.6
thioredoxin reductase 1.6
PCP 1.6
RNase 1.6
CPS 1.6
ceruloplasmin 1.6
heparinase 1.6
CYP3A4 1.6
chloramphenicol acetyltransferase 1.6
TPP 1.5
acyl-CoA synthetase 1.5
11beta-hydroxysteroid dehydrogenase 1.5
glucose-6-phosphate dehydrogenase 1.5
tyrosine aminotransferase 1.5
CPR 1.5
papain 1.5
ribonuclease 1.5
ribonuclease 1.5
phosphoglucomutase 1.5
succinate dehydrogenase 1.5
caspase-3 1.4
RNase 1.4
dopamine beta-hydroxylase 1.4
luciferase 1.4
beta-glucosidase 1.4
indoleamine 2,3-dioxygenase 1.4
TPP 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
phosphoinositide 3-kinase 1.4
citrate synthase 1.3
caspase-9 1.3
glutathione S-transferase 1.3
chalcone synthase 1.3
collagenase 1.3
sialyltransferase 1.3
sialyltransferase 1.3
sialyltransferase 1.3
trypsin 1.3
caspase-1 1.3
transcriptase 1.2
reverse transcriptase 1.2
glutathione reductase 1.2
furin 1.2
ricin 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
aryl hydrocarbon hydroxylase 1.2
beta-glucosidase 1.2
aldose reductase 1.2
dipeptidyl peptidase IV 1.2
lactate dehydrogenase 1.1
ornithine transcarbamylase 1.1
HSD 1.1
hexokinase 1.1
tryptophan hydroxylase 1.1
ERK 1.1
monoamine oxidase 1.1
creatine kinase 1.0
TdT 1.0
thermolysin 1.0
botulinum neurotoxin 1.0
glutaminase 1.0
PARP 0.9
adenylate kinase 0.9
DCF 0.9
glutathione peroxidase 0.9
cathepsin B 0.8
phosphoenolpyruvate carboxykinase 0.8
phosphoenolpyruvate carboxykinase 0.8
HIV-1 protease 0.8
alpha-glucosidase 0.8
PAL 0.8
NADH dehydrogenase 0.8
gamma-glutamyl transpeptidase 0.7
elastase 0.7
phosphoenolpyruvate carboxykinase 0.7
peroxidase 0.7
lipoprotein lipase 0.7
beta-galactosidase 0.6
focal adhesion kinase 0.6
IKK 0.6
diamine oxidase 0.6
CDR 0.6
DNase 0.6
beta-glucuronidase 0.6
SPC 0.5
alpha-amylase 0.5
lipase 0.5
MDP 0.5
histone acetyltransferase 0.5
ascorbate peroxidase 0.4
tissue plasminogen activator 0.4
acetylcholinesterase 0.4
alkaline phosphatase 0.3
kallikrein 0.3
alcohol dehydrogenase 0.3
ornithine decarboxylase 0.2
RNA polymerase 0.2
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Compound
5-Nitroisatin 11.9
Vindorosine 11.9
D-NONOate 11.9
Tetrahydroneopterin 10.9
8-iso-PGF2beta 10.9
8-Br-cGMP 10.1
8-iso-PGE1 9.7
cGMP 9.6
SB 200646 9.6
Caracemide 9.1
Eudesmin 9.1
C7H9N3O3 9.1
LNO2 9.0
Methylene blue 8.9
Acetylcholine chloride 8.9
3-Chlorotyrosine 8.9
Capillarisin 8.9
8-iso-PGE2 8.6
NPR 8.6
ethanimidamide 8.6
GMP 8.4
Lubiprostone 8.3
Nitroprusside 8.3
D-Arginine 8.3
HM-5 8.3
DEA 8.3
DEA 8.3
DETA 8.2
DEA 8.2
Indicaxanthin 8.2
Isatin 8.1
C3H7NO2 8.1
Cubebin 8.1
N-(2-hydroxyethyl)nicotinamide 8.1
Sinensetin 8.1
Nicorandil 8.0
Sodium bromide 8.0
Lys-vasopressin 8.0
Nitro-L-arginine 8.0
Piloty's acid 7.9
BW619C89 7.9
imidazo[1,5-a]pyridine 7.7
Adrenochrome 7.6
Amarogentin 7.6
2-aminoethyl diphenylborinate 7.6
2-aminoethyl diphenylborinate 7.6
1-phenylethanone 7.6
Amaranthin 7.6
1-phenylethanone 7.6
1-phenylethanone 7.6
1-phenylethanone 7.6
Relaxant 7.5
NS 1619 7.5
Equilin 7.5
BNP 7.5
Nitroglycerin 7.4
Sildenafil 7.4
Linalyl acetate 7.4
Butylidenephthalide 7.4
1-phenylethanone 7.4
2-(4-morpholinyl)ethyl 7.3
Formycin A 7.3
3H-imidazo[4,5-b]pyridine 7.3
3H-imidazo[4,5-b]pyridine 7.3
3H-imidazo[4,5-b]pyridine 7.3
Etiocholanolone 7.2
AA861 7.2
1-phenylethanone 7.2
2-(4-morpholinyl)ethyl 7.2
Sodium azide 7.2
3H-imidazo[4,5-b]pyridine 7.2
Ginsenoside Re 7.1
nitric oxide 7.1
2,3-dimercapto-1-propanol 7.0
2,3-dimercapto-1-propanol 7.0
DT3 7.0
Zinc protoporphyrin 7.0
1-EBIO 6.9
Rutaecarpine 6.9
Rutaecarpine 6.9
Biliverdin 6.9
Sepiapterin 6.8
6-Keto-PGF1a 6.8
3-ethylphenol 6.8
1-phenyl-1-propanol 6.8
Arg-vasopressin 6.8
Protoporphyrin IX 6.8
1,2,5-oxadiazole 6.7
Cromakalim 6.7
2,4-DP 6.6
Polygodial 6.6
Tetraethylammonium 6.6
Tetrahydropalmatine 6.6
XTP 6.5
4-AP 6.5
GC-1 6.5
PD 123319 6.5
TEA 6.4
TEA 6.4
Pinacidil 6.4
Dorzolamide 6.4
N-phenylbenzamide 6.3
ETN 6.3
Echinacoside 6.3
PKF 6.3
eicosa-8,11,14-trienoic acid 6.3
MIF-I 6.2
Galacturonic acid 6.2
BQ 123 6.2
Phenylarsine oxide 6.2
BayK8644 6.2
Kallidin 6.2
Pyrogallol 6.2
Danshensu 6.2
Scoparone 6.1
hexanamide 6.1
Diamide 6.1
Bradykinin 6.1
Quisqualic acid 6.0
Anacardic acid 6.0
Glibenclamide 6.0
Sodium cyanide 6.0
Heme 6.0
adenylate 6.0
Monocrotaline 5.9
arginine 5.9
1,3-dihydro-2H-benzimidazol-2-one 5.9
SKF 525A 5.9
Acenaphthene 5.8
6R-BH4 5.8
2-heptanol 5.8
Genipin 5.8
Quinacrine 5.8
Acetophenone 5.8
Chlorpheniramine 5.8
Hemin 5.7
Hemin 5.7
Hemin 5.7
Hemin 5.7
Hemin 5.7
Quinacrine 5.7
Chlorpheniramine 5.7
Ethacrynic acid 5.7
ITG 5.7
Hoe 5.6
alpha-Amanitin 5.6
NMA 5.6
DAMP 5.6
Milrinone 5.6
Zingerone 5.6
BaCl2 5.6
Imperatorin 5.6
1-amino-1,3-cyclopentanedicarboxylic acid 5.6
C3H7NO 5.6
Dihydralazine 5.6
ACh 5.6
C6H12 5.6
Butein 5.6
Phenylephrine 5.5
CIT 5.5
ASE 5.5
C6H12 5.5
20-HETE 5.5
5-MeOT 5.5
Carbachol 5.5
GTP 5.5
6-aminonicotinamide 5.5
Dithiothreitol 5.5
hydroxylamine 5.5
trimethyllysine 5.4
hydroxylamine 5.4
cAMP 5.4
C3H7NO 5.4
12-hydroperoxyeicosatetraenoic acid 5.4
9-AC 5.4
Tiron 5.4
Ethacrynic acid 5.4
DMPP 5.4
3,4-DAP 5.3
Hydroxocobalamin 5.3
IPN 5.3
Umbelliferone 5.3
25-Hydroxycholesterol 5.3
Sodium lactate 5.3
Sarin 5.3
Xamoterol 5.3
Dihydroergotamine 5.2
Dithiothreitol 5.2
PBZ 5.2
202-791 5.2
Oxymetazoline 5.2
prostacyclin 5.2
Ethionine 5.2
Nitrite 5.2
Tempol 5.2
Ginkgolide B 5.1
DDA 5.1
DDA 5.1
TGR 5.1
DDA 5.1
Phosphoramidon 5.1
Dibutyryl cyclic AMP 5.1
Pirenzepine 5.1
Dibutyryl cyclic AMP 5.1
Forskolin 5.1
Trifluoperazine 5.1
ISDN 5.1
Inositol phosphate 5.1
Chlorite 5.0
Embelin 5.0
Tetrahydrobiopterin 5.0
DTT 5.0
AMP 5.0
Arachidonic acid 5.0
methanesulfonamide 5.0
methanesulfonamide 4.9
OPDA 4.9
Soman 4.9
DTT 4.9
nitrosobenzene 4.9
NPPB 4.9
Exotoxin 4.9
dADP 4.9
Melittin 4.9
Digitonin 4.9
nonyl 4.9
Ferrous sulfate 4.9
Repaglinide 4.8
DAMP 4.8
Ruthenium red 4.8
Nitrite 4.8
AT-101 4.8
Tirofiban 4.8
AT-101 4.8
Evodiamine 4.8
8-iso-PGF2alpha 4.8
Delphinidin 4.8
AT-101 4.8
1,3-benzodioxole 4.8
Harmaline 4.8
Indigo Carmine 4.7
Rhodopsin 4.7
M 3 4.7
LY 294002 4.7
Wortmannin 4.7
Tranylcypromine 4.7
Evodiamine 4.7
1H-pyrazole 4.7
11-cis-retinal 4.7
Ergonovine 4.7
MoO4 4.7
Halothane 4.7
PGG2 4.7
4-NQO 4.7
SPM 4.6
CPT 4.6
Na2S 4.6
L-Lactate 4.6
benzenesulfonyl fluoride 4.6
pentaerythritol 4.6
1-heptanol 4.6
Xanthohumol 4.6
propylbenzene 4.6
Hesperidin 4.6
Nalbuphine 4.6
Nordihydroguaiaretic acid 4.6
Acteoside 4.6
Buthionine sulfoximine 4.5
NMDA 4.5
Nigericin 4.5
Tetrodotoxin 4.5
CPT 4.5
prostaglandin F2alpha 4.5
Isoliquiritigenin 4.5
Guo 4.5
PPADS 4.5
ADMA 4.5
1H-pyrrole-2,5-dione 4.5
TETA 4.5
Pro-Gly 4.5
MPT 4.4
2-imidazolidinone 4.4
AME 4.4
methyl carbamate 4.4
1H-pyrazole 4.4
7beta-hydroxycholesterol 4.4
Osthole 4.4
3'-AMP 4.4
Prazosin 4.4
Nobiletin 4.4
Sesamin 4.4
Piceatannol 4.4
Benzyl alcohol 4.3
COX 4.3
ETA 4.3
Indomethacin 4.3
Barbiturate 4.3
Pyridoxine 4.3
prostaglandin F1 4.3
SC-1 4.3
Ang II 4.3
SC-1 4.3
Mesalamine 4.3
NEM 4.3
DMPP 4.3
Flavone 4.2
2,4-dichlorophenyl 4.2
2,4-dichlorophenyl 4.2
sodium 4.2
12-hydroxyeicosatetraenoic acid 4.2
Isoflurane 4.2
PHE 4.2
Cytochalasin D 4.2
manganese 4.2
Ryanodine 4.2
Carbamate 4.2
CPA 4.2
Biotin 4.2
1H-imidazole 4.2
Cyclopiazonic acid 4.1
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