Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.6.1.2 (
guanylate cyclase
)
8,497
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
guanylyl cyclase
11.9
COD3
11.9
prostaglandin I2 (prostacyclin) receptor
11.9
GUANYLATE CYCLASE
11.9
guanylate cyclase 1, soluble, beta 3
11.9
guanylate cyclase
11.9
guanylate cyclase-activating protein 2
11.9
heat-stable enterotoxin receptor
11.7
GCAP2
11.6
GCAP3
11.5
Guanylate cyclase
11.4
GCAP1
11.3
CORD5
11.3
GUCA1B
11.3
GCAP
11.2
GUCY2D
11.2
retinal degeneration 3
11.1
ROS-GC1
11.1
GC-E
11.0
G-protein-coupled receptor kinase 1
10.9
more...
Disease
COD3
11.9
relaxation; bladder
11.9
difficile; Clostridium
11.9
CORD5
11.3
LCA12
10.9
CORD6
10.1
Chronic idiopathic constipation
10.0
Congenital sodium diarrhea
9.9
Cone dystrophy
9.7
Macular dystrophy
9.3
Multiple carboxylase deficiency
9.1
Central areolar choroidal dystrophy
8.9
CHEST
8.9
Hereditary retinal dystrophies
8.4
dual personality
8.2
Unilateral renal artery stenosis
8.2
NAME
7.5
PAPA
7.2
Biotin deficiency
6.9
PDE
6.9
more...
Symptom
Simple constipation
11.9
Functional abdominal pain
6.4
Functional constipation
6.0
chronic constipation
5.2
bloating
4.5
Lower urinary tract symptoms
4.3
constipation
4.2
Anoxia
3.8
clonus
3.3
bladder pain
3.3
hyperoxia
3.2
loss of balance
3.1
orofacial pain
3.0
hyperesthesia
2.8
abdominal cramps
2.8
despair
2.8
Gastrointestinal symptoms
2.7
angina
2.6
diarrhea
2.6
spasm
2.5
more...
Drug
N-Hydroxyguanidine
10.3
Carperitide
9.6
Methylene blue
9.3
Sodium nitroprusside
9.3
Nipradilol
8.9
Leminoprazole
8.9
7-Nitroindazole
8.0
Quinaprilat
7.8
Avanafil
7.7
Equilin
7.6
Cicletanine
7.5
Pentaerythritol tetranitrate
7.3
Molsidomine
7.2
L-Homoarginine
7.2
Nitric Oxide
6.9
Viagra
6.7
Viagra
6.6
nitroglycerin
6.5
Gly-Tyr-Gly
6.5
Regitine
6.5
more...
Enzyme
EC 1.13.11.49
11.9
guanylate cyclase
11.9
isoflavone 7-O-glucosyltransferase
9.6
cGMP phosphodiesterase
9.4
PKG
9.4
2-hydroxyisoflavanone dehydratase
9.1
cytidylate cyclase
8.7
retinol isomerase
8.0
2-hydroxyisoflavanone synthase
7.9
NO synthase
7.7
rhodopsin kinase
7.7
lecithin-retinol acyltransferase
7.6
EC 5.3.3.2
7.5
steroid 11beta-hydroxylase
7.5
phosphodiesterase
7.3
NOS
7.0
PDE
6.9
heme oxygenase
6.8
adenylate cyclase
6.6
ecdysone 20-monooxygenase
6.4
more...
Compound
D-NONOate
11.9
Vindorosine
11.9
5-Nitroisatin
11.9
Tetrahydroneopterin
10.9
8-iso-PGF2beta
10.9
8-Br-cGMP
10.1
8-iso-PGE1
9.7
cGMP
9.6
SB 200646
9.6
C7H9N3O3
9.1
Caracemide
9.1
Eudesmin
9.1
LNO2
9.0
Methylene blue
8.9
Acetylcholine chloride
8.9
Capillarisin
8.9
3-Chlorotyrosine
8.9
8-iso-PGE2
8.6
NPR
8.6
ethanimidamide
8.6
more...