Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.6.1.2 (
guanylate cyclase
)
8,497
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Highly purified
EF-Ts
from E. coli does contain
guanylate cyclase
activity, which is absent from other purified transfer factors, such as EF-Tu and EF-G. Guanylate cyclase activity has been characterized by its sensitivity to inhibitors and substrate specificity. Although the physicochemical properties of
guanylate cyclase
are closely related to those of
EF-Ts
, it does not appear to be a contaminant of this transfer factor, but a specific enzyme. The possible role of
guanylate cyclase
in protein synthesis is discussed.
...
PMID:[Guanyl cyclase activity in the EF-T elongation factor of Escherichia coli]. 2 Oct 22
