Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.6.1.1 (adenylate cyclase)
 19,190 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
adenylate cyclase 10.7
chorionic gonadotropin, beta polypeptide 10.7
adenyl cyclase 10.6
ATP pyrophosphate-lyase 10.6
3',5'-cyclic AMP phosphodiesterase 10.1
adenylate cyclase-inhibiting 10.1
guanine nucleotide regulatory protein 9.7
CRTC2 protein 9.7
JTV1 9.7
OR14I1 9.7
Cyclic AMP phosphodiesterase 9.2
PACAPR 9.1
Dihydropyrimidinase-like 3 9.1
adenylate cyclase 4 9.1
GPCR21 9.1
adenylate cyclase-coupled 9.1
adenylate cyclase 6 8.9
EP3A 8.8
putative inhibitory receptor 8.7
OR51B5 8.7
phospholipase C, zeta 1 8.7
guanine nucleotide-binding regulatory protein 8.7
ADCY8 8.6
PACAP receptor 8.6
nucleotide binding protein 8.6
OR2AT4 8.4
3 beta-HSD type II 8.4
adenylyl cyclase 2 8.3
ACEH 8.2
cyclic AMP phosphodiesterase 8.2
guanine nucleotide binding protein 8.1
VPAC2 8.1
K-RAS protein 8.1
NEM2 8.1
GAF1 8.1
RGS9 protein 8.1
PACAP 8.1
VIP2 8.1
nucleotide-binding protein 8.1
VIP1 8.0
seven transmembrane domain protein 8.0
platelet ADP receptor 7.9
Dopamine receptor D4 7.9
SCAF4 7.9
Nucleoside diphosphokinase 7.9
GNG4 7.9
GPR22 7.9
guanine nucleotide-binding protein 7.9
Guanylate cyclase 7.8
pituitary adenylate cyclase-activating polypeptide 7.8
CT A 7.8
IRA2 7.8
PTHRP 7.8
GTP binding protein 7.7
PAC1 7.7
EP2A 7.7
histone deacetylase HD1 7.7
DHP1 7.7
LANCL2 7.7
ADCYAP1 7.7
secretin receptor 7.6
VPAC1 7.6
GTP-binding protein 7.6
IRA1 7.6
cyclic nucleotide phosphodiesterase 7.5
PRP mRNA 7.5
Golf alpha 7.5
cyclic AMP specific phosphodiesterase 7.5
smk1 7.5
somatostatin receptor 1 7.5
vasoactive intestinal peptide (VIP) 7.5
vasoactive intestinal peptide 7.4
breast cancer associated gene 1 7.4
SHEP1 7.4
ARPP-21 7.4
OR17-40 7.4
ribonuclease/angiogenin inhibitor 7.4
ADCY1 7.4
conserved helix-loop-helix ubiquitous kinase 7.4
CaM-PDE 7.4
more...
Disease
Fibrinous peritonitis 9.7
Acute ischaemic heart disease 9.7
temporal lobe disorder 9.1
Glucagon resistance 8.7
growth hormone-producing pituitary tumor 8.7
Chronic hemolytic anemia 8.4
acute infectious nonbacterial gastroenteritis 8.4
non toxic multinodular goiter 8.4
NEM2 8.1
Bordetella infection 7.9
HYD2 7.7
pertussis 7.2
Bordetella 7.2
GGF2 7.2
Aluminum intoxication 7.2
pseudohypoparathyroidism 7.0
Transient neonatal hypothyroidism 6.9
cholera 6.8
pseudopseudohypoparathyroidism 6.6
narcotic dependence 6.4
ADH3*1 6.4
Eberth 6.2
learning defect 6.1
HCA1 6.0
osteoblastic osteosarcoma 6.0
phosphaturia 5.9
Calcium deficiency 5.8
hypercalcemia of malignancy 5.8
BEN 5.8
SCH 5.7
radiation leukemia 5.6
MKS3 5.6
Pituitary 5.5
PDE 5.5
Leydig cell tumor 5.5
Retinal vasculitis 5.4
nephrogenic diabetes insipidus 5.4
secondary cardiomyopathy 5.3
Hurthle cell carcinoma 5.3
Takahara 5.2
Hurthle cell adenoma 5.1
nasal infection 5.1
cerebral neoplasm 5.1
OHS 5.1
Congenital nephrogenic diabetes insipidus 5.1
PAPA 5.0
CPX 5.0
PHP 5.0
OA2 4.9
Teratocarcinoma 4.9
adaptation reaction 4.9
thrombopathy 4.8
adrenal cancer 4.7
acrodysostosis 4.7
Idiopathic hypercalciuria 4.7
Opiates 4.7
IRD 4.7
perinephritis 4.7
TD2 4.7
Hepatocarcinogenesis 4.7
chronic brain syndrome 4.7
SMS 4.6
Infection induced 4.5
toxic adenoma 4.5
osteomyelofibrosis 4.5
Inhalant abuse 4.4
myxedema 4.4
Carotid body 4.4
Carotid body 4.4
Carotid body 4.4
Graves' disease 4.4
pituitary tumor 4.4
anthrax 4.4
Adie 4.4
Other variants 4.4
TD1 4.4
Diastolic heart failure 4.3
sympathomimetic 4.3
HYP 4.3
NMS 4.2
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Symptom
sinus pain 5.8
Orthostasis 5.6
skin pain 4.4
dysosmia 4.2
photopsia 3.6
Anoxia 3.6
leg cramps 3.5
polyuria 2.9
rundown 2.7
Catch 2.7
Decreased activity 2.6
hyperemesis gravidarum 2.6
twitching 2.5
autodigestion 2.4
Excitability 2.4
clonus 2.2
starvation 2.1
eds 1.6
POA 1.6
polydipsia 1.6
ketonuria 1.6
Gastrointestinal symptoms 1.5
incoordination 1.5
hypothermia 1.4
dry eye 1.3
cachexia 1.2
diarrhea 1.0
general problem 0.9
memory loss 0.9
acute stress 0.8
DNA marker 0.8
analgesia 0.8
dry skin 0.7
emaciation 0.6
urinary frequency 0.6
hypoproteinemia 0.5
nasal congestion 0.5
decreased appetite 0.5
chronic constipation 0.4
fasciculation 0.4
acute pain 0.3
bitter taste 0.2
Neuropathic pain 0.2
tremor 0.2
HSA 0.1
insomnia 0.1
anosmia 0.1
photophobia 0.1
despair 0.0
enuresis 0.0
functional recovery -0.0
hypocapnia -0.0
anorexia -0.1
hunger -0.2
exhaustion -0.2
vomiting -0.3
constipation -0.3
headache -0.4
rhinorrhea -0.5
spasm -0.6
seizures -0.6
hypercapnia -0.7
agitation -0.9
cancer pain -0.9
syncope -0.9
bone pain -0.9
collapse -0.9
flushing -0.9
spasticity -1.0
myalgia -1.0
erythema -1.0
exertional dyspnea -1.0
pain -1.1
vertigo -1.1
cerebellar ataxia -1.1
thinning -1.2
acidity -1.2
anesthesia -1.2
respiratory distress -1.2
pelvic pain -1.3
more...
Drug
Adehl 10.1
2-Fluoroadenosine 9.7
Diphenoxylate hydrochloride 9.7
Strophanthin-G 9.1
Forskolin 9.0
Quazinone 8.7
Nufenoxole 8.7
Parotin 8.7
Methoxamine hydrochloride 8.4
Thiodigalactoside 8.4
Fengabine 8.4
Butaprost 8.1
2'-Deoxyadenosine 7.6
SR 57746A 7.5
Amiloride hydrochloride 7.5
Alprenolol 7.5
Oxypertine 7.4
3-Methoxybenzamide 7.4
Sulotroban 7.4
Benzenesulfonyl 7.4
Denopamine 7.1
Beraprost 6.9
Formycin 6.9
p-Chlorophenyl 6.8
Trifluoperazine 6.7
Piroximone 6.7
Tiotidine 6.7
Penfluridol 6.6
Piriprost 6.6
Secretin 6.6
Dopexamine hydrochloride 6.5
Iloprost 6.5
Rolipram 6.4
Stelazine 6.4
Salmon calcitonin 6.4
Enprostil 6.4
GRF 6.3
Clebopride 6.3
Tetragastrin 6.2
Bitrex 6.2
Periactin 6.1
Azosemide 6.1
PTH 6.1
Glucagon 6.1
Enprofylline 6.1
Sulprostone 6.0
Fenoldopam 5.9
Lisuride 5.9
Bisolvon 5.9
Epinastine 5.9
Renzapride 5.9
Flupenthixol 5.9
Sodium propionate 5.8
Fluphenazine 5.8
Deoxyadenosine 5.8
Ridogrel 5.7
Sulpiride 5.6
Theophylline 5.5
hCRH 5.4
Remoxipride 5.3
Flesinoxan 5.3
Demeclocycline 5.3
Rioprostil 5.2
ICI 5.2
Papaverine 5.1
Platelet Activating Factor 5.1
Regadenoson 5.1
Clonidine 5.1
Histamine 5.1
Berotec 5.1
Triprolidine 5.1
Gallamine 5.0
Pertussis vaccine 5.0
CTZ 5.0
Pitressin 4.9
Flosequinan 4.9
Trimipramine 4.9
Sodium nitroprusside 4.9
4-Hydroxytamoxifen 4.9
Apomorphine 4.9
more...
Enzyme
adenylate cyclase 10.7
cytidylate cyclase 8.5
VIP1 7.6
phosphodiesterase 7.3
cGMP phosphodiesterase 7.0
3'(2'),5'-bisphosphate nucleotidase 7.0
N-acetylneuraminylgalactosylglucosylceramide 6.8
PDE 6.7
guanylate cyclase 6.6
K+-transporting ATPase 6.4
pyroglutamyl peptidase II 6.1
25-hydroxyvitamin D3 1alpha-hydroxylase 6.1
phospholipase C 6.0
AMPK 5.9
5'-nucleotidase 5.8
AMP nucleosidase 5.8
NAD glycohydrolase 5.8
ADP-ribosyltransferase 5.7
ADP-ribosyltransferase 5.7
phospholipid methyltransferase 5.7
PI-PLC 5.5
methionine decarboxylase 5.5
leucine aminotransferase 5.5
carboxypeptidase S 5.5
adenosine deaminase 5.5
adenosine deaminase 5.5
tryptophanase 5.4
protein kinase 5.4
destabilase 5.4
arylalkylamine N-acetyltransferase 5.3
dynein ATPase 5.3
NAAT 5.2
ecdysone 20-monooxygenase 5.2
protein kinase C 5.2
pyruvate dehydrogenase phosphatase 5.2
L-arabinose isomerase 5.1
PAPS reductase 5.1
EC 2.4.1.11 5.1
Mg2+-ATPase 5.0
trimetaphosphatase 4.9
nucleoside diphosphokinase 4.9
GMP reductase 4.9
6-phosphofructo-2-kinase 4.9
phosphofructokinase 1 4.9
protein methylase II 4.8
GRK2 4.7
collagenase 3 4.7
urocanase 4.7
oligopeptidase B 4.7
phosphorylase kinase 4.7
phosphorylase 4.7
p-nitrophenylphosphatase 4.6
iodothyronine 5'-deiodinase 4.6
5beta-reductase 4.5
nucleotidase 4.5
Ins(1,4,5)P3 3-kinase 4.5
prostacyclin synthase 4.4
triphosphatase 4.4
CPT 4.4
adenosine kinase 4.4
N-acetyltransferase 4.4
arabinose isomerase 4.4
thromboxane synthase 4.4
trehalase 4.3
PHT 4.3
splicing endonuclease 4.3
GPI-specific phospholipase C 4.3
PKG 4.3
CPT 4.3
5-oxoprolinase 4.3
histidine decarboxylase 4.3
gluconokinase 4.3
aromatic L-amino acid decarboxylase 4.2
venom phosphodiesterase 4.2
cytochrome P-450scc 4.1
gastricsin 4.1
hormone-sensitive lipase 4.1
tryptophan 2,3-dioxygenase 4.1
phospholipase A2 4.1
AFR 4.1
more...
Compound
9-(Tetrahydro-2-furyl)adenine 10.7
C22H34O7 10.7
2-Fluoroadenosine 9.7
1,3-dimercapto-2-propanol 9.7
Kaurenol 9.7
Ergosine 9.1
Coleonol 9.1
SQ 21,611 9.1
Forskolin 9.0
8-Bromo-cyclic AMP 9.0
benzo[cd]indol-2(1H)-one 8.9
1-phenyl-1H-pyrrole 8.7
SQ 20009 8.6
Sulmazole 8.5
Tenulin 8.4
Adchnon 8.4
Manganous chloride 8.4
Tenulin 8.4
Skyrin 8.1
Nolinium bromide 8.1
8-Bromoadenosine 7.9
8-Bromoadenosine 7.9
8-Bromoadenosine 7.9
8-Bromoadenosine 7.9
8-Bromoadenosine 7.9
8-Bromoadenosine 7.9
Sarcolysine 7.9
C7H9N3O3 7.9
Caracemide 7.9
3-ethyl-1H-indole 7.9
8-Bromoadenosine 7.9
Lys-vasopressin 7.8
6-keto PGE1 7.7
SC-13504 7.7
beta-Lumicolchicine 7.5
8-iso-PGE1 7.5
Pamine 7.5
2-imidazolidinone 7.5
prostaglandin E1 7.5
AMP 7.4
Labetalol hydrochloride 7.4
Labetalol hydrochloride 7.4
Menadiol 7.4
C5H11NO2 7.4
Labetalol hydrochloride 7.4
cAMP 7.4
Dibutyryl cyclic AMP 7.3
Dibutyryl cyclic AMP 7.3
PGD3 7.2
Lilial 7.2
Prenalterol 7.2
Gramine 7.2
5-Iodotubercidin 7.1
Tetrahydroberberine 7.1
Tetrahydroberberine 7.1
5-Iodotubercidin 7.1
5-Iodotubercidin 7.1
Lanthionine ketimine 7.1
5-Iodotubercidin 7.0
Levorphanol 7.0
adenylate 6.9
1,3-cyclopentanedicarboxylic acid 6.9
20-hydroxycholesterol 6.9
Sangivamycin 6.8
LNO2 6.8
Chlordimeform 6.8
Pinane 6.8
Trifluoperazine 6.7
Bulbocapnine 6.7
2-phenylalanine 6.7
5-MeOT 6.7
GTP 6.6
PGB1 6.6
Kallidin 6.6
S-phenyl 6.6
Spiperone 6.6
PAPP 6.6
S-phenyl 6.6
Methoxamine 6.5
Etorphine 6.5
more...