Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.6.1.1 (adenylate cyclase)
19,190 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
adenylate cyclase 18122
AMP 3740
phosphodiesterase 1777
GTP 1741
Sep 1330
Mol 1257
ATP 1080
adenyl cyclase 894
glucagon 854
ADP 787
insulin 708
calmodulin 686
parathyroid hormone 562
vasoactive intestinal peptide 502
guanylate cyclase 464
polypeptide 454
vasopressin 442
somatostatin 426
calcitonin 422
cAMP-dependent protein kinase 421
ATPase 417
vasoactive intestinal peptide (VIP) 396
ACTH 348
membrane-bound 333
pituitary adenylate cyclase-activating polypeptide 328
PKA 312
GDP 304
beta-endorphin 298
PTH 283
secretin 273
beta 1 249
adenosine receptor 244
GTP-binding protein 242
GTPase 221
VIP 197
membrane protein 188
ATP pyrophosphate-lyase 186
thrombin 181
cyclic AMP phosphodiesterase 181
substance P 178
angiotensin II 177
prolactin 173
collagen 173
FSH 169
guanine nucleotide regulatory protein 168
5-hydroxytryptamine 167
PKC 166
olfactory 165
SCH 161
alkaline phosphatase 161
nitric oxide synthase 160
muscarinic receptor 158
NAD 152
cyclooxygenase 152
guanine nucleotide-binding protein 146
Gen 146
cyclic nucleotide phosphodiesterase 144
adenosine deaminase 140
cytokine 137
adenylyl cyclase 133
arginine vasopressin 132
GMP 131
growth hormone 126
bradykinin 123
phospholipase A2 123
guanine nucleotide binding protein 119
neuropeptide Y 116
tyrosine kinase 116
GABA 116
PACAP 115
osteosarcoma 115
5-HT1A 113
epidermal growth factor 112
chorionic gonadotropin 111
tyrosine hydroxylase 110
glycoprotein 110
opioid receptor 109
collagenase 108
5'-nucleotidase 107
GHRH 106
more...
Disease
pertussis 1771
cholera 1352
Bordetella 545
tumor 456
neuroblastoma 282
cancer 278
glioma 221
diabetes 214
depression 198
lymphoma 185
SCH 161
Pituitary 155
hypertension 151
osteosarcoma 136
heart failure 132
ischemia 117
Graves' disease 116
SDS 91
asthma 90
melanoma 85
pheochromocytoma 80
cold 77
carcinoma 76
hypothyroidism 72
PDE 72
pseudohypoparathyroidism 70
hyperthyroidism 70
uterus 66
obesity 66
NAME 66
SEM 63
chronic renal failure 63
astrocytoma 57
hypercalcemia 56
Alzheimer's disease 56
hepatocellular carcinoma 54
anthrax 53
congestive heart failure 52
breast cancer 51
type 2 diabetes 50
APC 49
intraocular pressure 47
leukemia 47
schizophrenia 45
hyperglycemia 43
stroke 42
migraine 42
adenocarcinoma 42
Parkinson's disease 38
cystic fibrosis 38
atherosclerosis 36
goiter 36
adenoma 36
sympathomimetic 35
pituitary tumor 35
myocardial infarction 33
myocardial ischemia 32
tumor growth 32
idiopathic thrombocytopenic purpura 31
cardiomyopathy 30
hyperparathyroidism 30
infectious diseases 30
insulinoma 29
erythroleukemia 29
aqueous humor 25
sarcoma 24
SMS 24
Mycobacterium 24
carcinogenesis 24
MCF 23
essential hypertension 23
dilated cardiomyopathy 23
nephrogenic diabetes insipidus 23
bipolar disorder 22
plaque 22
hyperinsulinemia 21
hypoglycemia 21
metastases 21
uremia 21
prostate cancer 21
more...
Symptom
pain 74
diarrhea 71
starvation 65
seizures 32
analgesia 30
anesthesia 29
hypothermia 27
headache 25
vomiting 16
polyuria 14
tremor 13
fatigue 9
collapse 9
functional recovery 8
anorexia 8
cachexia 8
insomnia 7
exhaustion 7
twitching 7
acute stress 5
constipation 5
respiratory distress 5
acidity 4
memory loss 4
erythema 4
dry eye 4
polydipsia 4
agitation 4
angina 4
cough 4
Anoxia 4
dyspnea 3
hunger 3
weakness 3
spasm 3
incoordination 3
thinning 3
syncope 3
acute pain 3
hypercapnia 3
stigma 3
nausea 3
dystonia 2
Ill 2
ataxia 2
vertigo 2
flushing 2
rundown 2
nausea and vomiting 2
chest pain 2
Catch 2
hyperemesis gravidarum 2
eds 2
clonus 2
Decreased activity 2
myalgia 2
HSA 2
spasticity 2
sleepiness 1
sinus pain 1
despair 1
dysosmia 1
bitter taste 1
POA 1
enuresis 1
skin pain 1
Neuropathic pain 1
fasciculation 1
emaciation 1
hypocapnia 1
general problem 1
autodigestion 1
nasal congestion 1
ENT 1
exertional dyspnea 1
cerebellar ataxia 1
chronic constipation 1
Welt 1
pelvic pain 1
apathy 1
more...
Drug
Forskolin 814
PTH 284
Glucagon 152
Cardiovasc 135
Nephron 128
caffeine 126
ICI 118
Histamine 114
Dermatol 110
lysine 92
MAP 57
Theophylline 54
Ethanol 53
ROS 52
Clonidine 50
GRF 48
Angiotensin II 46
Indomethacin 45
Gel 45
Secretin 43
IL-2 35
CaCl2 34
CaCl2 34
CaCl2 34
-deoxyadenosine 33
lactose 31
Iloprost 29
Atropine 29
Trifluoperazine 28
9-THC 28
ACT 27
IFN-gamma 27
Asn 24
EE2 24
Ouabain 23
Rolipram 22
Apomorphine 22
NADH 22
Sulpiride 18
Sodium nitroprusside 18
ascorbate 17
Phentolamine 16
CSF 16
ETA 15
Salbutamol 15
Luteinizing 14
CTX 14
nitroglycerin 13
Retinoic acid 13
MgSO4 13
Ringer's solution 12
Adenosine deaminase 12
Cimetidine 12
Cimetidine 11
vitamin E 11
Glycerol 10
Papaverine 10
Butaprost 10
niacin 10
Alprenolol 9
Salmon calcitonin 9
Alanine 8
Nephron 8
HCG 8
Monensin 8
Leaf 8
Amiloride 7
Reserpine 7
DHT 7
CTX 7
DHT 7
DNase I 7
Methylene blue 7
NAG 7
CTX 7
Fenoldopam 7
Clofibrate 6
DEX 6
NaI 6
DDAVP 6
more...
Enzyme
adenylate cyclase 19190
protein kinase 2106
phosphodiesterase 1785
protein kinase C 1115
phospholipase C 710
guanylate cyclase 482
ATPase 472
AMPK 434
mitogen-activated protein kinase 315
PDE 237
thrombin 177
alkaline phosphatase 164
trypsin 156
phospholipase A2 148
adenosine deaminase 141
adenosine deaminase 140
ERK 111
5'-nucleotidase 110
collagenase 108
tyrosine hydroxylase 105
phosphorylase 87
renin 81
calcineurin 78
luciferase 75
MEK 75
cGMP phosphodiesterase 74
acetylcholinesterase 55
NO synthase 53
chymotrypsin 47
peroxidase 46
RNA polymerase 43
monoamine oxidase 42
CPT 42
CPT 41
CPT 41
lipase 40
reverse transcriptase 38
acid phosphatase 38
phospholipase D 38
beta-galactosidase 37
lipoxygenase 37
choline acetyltransferase 36
phosphatidylinositol 3-kinase 35
lactate dehydrogenase 35
PARP 34
CaMKII 33
ADP-ribosyltransferase 33
ADP-ribosyltransferase 32
glucose-6-phosphatase 31
catalase 30
RNase 30
PKG 30
N-acetyltransferase 30
RNase 30
creatine kinase 29
Mg2+-ATPase 29
focal adhesion kinase 29
ornithine decarboxylase 27
NADPH oxidase 26
chloramphenicol acetyltransferase 25
carbonic anhydrase 24
AMP-activated protein kinase 24
hormone-sensitive lipase 23
alcohol dehydrogenase 23
NADPH oxidase 22
tyrosinase 21
myosin light chain kinase 20
VIP1 20
pyruvate kinase 20
triphosphatase 20
caspase-3 20
superoxide dismutase 19
MAP 19
ADH 19
phosphoenolpyruvate carboxykinase 19
neuraminidase 18
proteasome 18
histidine decarboxylase 17
CPR 17
glutathione S-transferase 17
more...
Compound
cAMP 5820
AMP 4358
calcium 2897
GTP 1754
Dec 1358
sodium 1332
ATP 1082
ADP 843
Forskolin 819
prostaglandin E1 808
Clin 797
ADP 793
ADP 792
glucose 783
acetate 691
cGMP 678
DNA 592
phosphate 584
Mg2+ 470
noradrenaline 461
adenylate 452
water 393
PGE2 391
TSH 364
prostacyclin 359
GDP 358
potassium 355
ACTH 350
Isoproterenol 332
arginine 312
manganese 300
5-HT 291
Adenosine 291
nitric oxide 280
tyrosine 249
GMP 242
Dopamine 218
NAD 211
glutamate 204
sulfate 196
ethanol 185
oxygen 173
PGE 171
Adrenal 165
lysine 157
leucine 154
NAD 152
Glucagon 152
Phe 147
NH2 145
His 140
iodine 135
alanine 132
glycerol 130
Insulin 127
caffeine 126
serine 125
salt 121
methionine 119
GABA 118
ICI 118
GABA 118
Norepinephrine 116
Histamine 114
galactose 106
PMA 106
Cardiol 105
PMA 105
SDS 103
ACh 102
aldosterone 102
TPA 96
TPA 96
threonine 90
urea 88
COS 87
EDTA 85
EDTA 85
Gly 84
PGD2 83
more...