Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.6.1.1 (adenylate cyclase)
19,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The expression of the fumarate reductase system of Escherichia coli is completely dependent on the presence of adenylate cyclase or cyclic AMP, but the cyclic AMP receptor protein (CRP) is not required. This suggests that cyclic AMP may function as an effector for a second gene activator protein, possibly Fnr, and thus form part of a redox-sensitive regulatory mechanism controlling the expression of anaerobic respiratory functions.
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PMID:Cyclic AMP and anaerobic gene expression in E. coli. 632 84