Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.2.3.23 (
GAS
)
957
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Group A
Streptococcus
(
GAS
,
Streptococcus pyogenes
) causes invasive infections including streptococcal toxic shock syndrome (STSS) and local infections. To our knowledge, this is the first report of a case of an invasive
GAS
infection with pneumonia and pleural empyema (PE) followed by STSS (disseminated intravascular coagulation [
DIC
] and acute renal insufficiency) in a healthy male adult. He received combined supportive therapies of PE drainage, anti-
DIC
agent, hemodialysis, and antimicrobials and eventually made a clinical recovery.
GAS
isolated from PE was found to have
emm1
/
speA
genes, suggestive of a pathogenic strain. Clinicians should be aware of the possibility of this disease entity (pneumonia, PE, and STSS) in healthy male adults as well as children and adult women.
...
PMID:Pleural empyema and streptococcal toxic shock syndrome due to
Streptococcus pyogenes
in a healthy Spanish traveler in Japan. 2872 62
