Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.2.3.23 (
GAS
)
957
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In young adults with acute pharyngitis, the main differential diagnosis is between
GAS
pharyngitis, EBV infectious mononucleosis, or other causes of
viral pharyngitis
. A positive RST does not differentiate
GAS
colonization from infection as is well illustrated by this case. Laboratory test results must be interpreted in the appropriate clinical context to be diagnostically meaningful. The RST only detects group A streptococci, but does not, of itself, implicate a causative role in the patient's pharyngitis. Without clinical correlation based on the clinical findings of
GAS
pharyngitis a positive RST may mislead the unwary physician to unnecessarily treat colonization rather than infection. I report an interesting case of a young adult who presented to the ED with no fever and acute pharyngitis. His RST was positive, and he was treated with procaine penicillin and released. Three days later he was re-admitted to the hospital with severe Herpes gingivostomatitis.
...
PMID:A positive rapid strep test in a young adult with acute pharyngitis: Be careful what you wish for! 2893 86