Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.2.2.7 (heparinase)
 1,270 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chondroitinase 194
ABC 153
proteoglycan 105
Sep 92
heparan sulfate proteoglycan 88
hyaluronidase 84
glucosamine 77
thrombin 67
antithrombin III 58
fibronectin 48
neuraminidase 47
Mol 46
glycoprotein 45
collagen 44
NMR 42
antithrombin 41
syndecan 36
thromboplastin 34
SDS 33
lipoprotein lipase 28
LDL receptor 26
core protein 26
mast cell 22
factor Xa 22
FGF 22
collagenase 20
apolipoprotein E 20
apoE 19
fibrinogen 19
heparanase 19
apolipoprotein 18
perlecan 17
prothrombin 17
Lipoprotein lipase 16
cytokine 16
lactoferrin 16
albumin 15
platelet factor 4 15
lipoprotein receptor-related protein 14
ferritin 14
vascular endothelium 14
lectin 13
beta 1 13
PLA 13
FGF-2 12
FGF receptor 12
Chondroitinase 12
membrane-bound 12
mucin 11
heparin cofactor II 11
tyrosine kinase 11
vascular endothelial growth factor 11
bFGF 11
HSPG 10
sulfotransferase 10
polypeptide 10
glypican 10
hepatic lipase 9
tumor necrosis factor 9
chemokine 9
hemoglobin 8
hepatocyte growth factor 8
amyloid precursor protein 8
galactosamine 8
envelope glycoprotein 8
Gen 8
epidermal growth factor 8
vitronectin 8
plasminogen 8
envelope protein 7
lymphoid 7
ESI 7
insulin 7
platelet-derived growth factor 7
membrane protein 7
Neuraminidase 7
Glypican-3 7
histone 6
cell surface receptor 6
delta 4 6
lipase 6
VEGF 6
tissue plasminogen activator 6
binding peptide 6
gut 6
heparin-binding protein 6
PI3K 6
tissue factor 6
CD44 6
urokinase-type plasminogen activator 6
low-density lipoprotein receptor 6
Antithrombin 6
THP 6
thrombospondin 5
L-selectin 5
ATP 5
ACT 5
alkaline phosphatase 5
Apolipoprotein E 5
LRP 5
ERK 5
tissue factor pathway inhibitor 5
TNF 5
FGFR1 5
EGF receptor 5
IL-8 5
lipopolysaccharide 5
prion 5
HDL 5
transforming growth factor-beta 5
TNF-alpha 5
fused 5
vascular endothelial growth factor receptor 2 4
heparin-binding EGF-like growth factor 4
fur 4
low density lipoprotein receptor 4
HVEM 4
sialidase 4
protease inhibitor 4
Met 4
IGFBP-5 4
kallikrein 4
MAPK 4
Gal 4
myosin 4
nectin-1 4
LPS 4
GST 4
mer 4
heparin binding protein 4
FGF2 4
N-glycanase 4
sulfatase 4
bradykinin 4
Pseudomonas 4
CD4 4
serine protease 4
beta-actin 4
P-selectin 4
angiotensin II 4
alpha-L-fucosidase 4
ACS 4
matrix metalloproteinase 4
thymus 4
TGF-beta 4
Platelet factor 4 4
RANTES 4
axonal 4
CXCL12 4
precursor protein 4
serum albumin 4
Fibroblast growth factor 4
metalloproteinase 4
IFN-gamma 4
Heparanase 4
agrin 3
OGD 3
TOF 3
phospholipase A2 3
phosphatidylinositol-specific 3
peroxidase 3
dimeric 3
proteoglycan core protein 3
Mucin 3
ras 3
neural cell adhesion molecule 3
PLA2 3
eNOS 3
lysozyme 3
vascular endothelial growth factor A 3
amphiregulin 3
white cell 3
PrP 3
aFGF 3
TBM 3
Glypican-1 3
von Willebrand factor 3
CD81 3
ERK1 3
osteogenic 3
Midkine 3
SMC 3
LPL 3
Connective tissue growth factor 3
phosphatidylinositol 3-kinase 3
nerve growth factor 3
tyrosine phosphatase 3
Hyaluronidase 3
type I collagen 3
IL-6 3
endostatin 3
Vascular endothelial growth factor 3
HEK 3
proximal tubule 3
thrombomodulin 3
PDGF 3
brain-derived 3
extracellular matrix protein 3
IL-3 3
protein kinase C inhibitor 3
PKC 3
IgE 3
CTGF 3
ATPase 3
bone morphogenetic protein 3
deoxyribonuclease 3
threonine 3
prion protein 3
receptor tyrosine kinase 3
insulin-like growth factor 3
SOD 3
chymase 3
protein kinase B 2
platelet-derived 2
stem cell factor 2
MRC 2
xanthine oxidase 2
CD14 2
connective tissue growth factor 2
MMP 2
Plasmin 2
IGFBP-4 2
megalin 2
tau protein 2
CS protein 2
SARS 2
Cytokine 2
glucosaminyl 2
EXT 2
LC-PTP 2
VLP 2
DPP8 2
alpha2-macroglobulin 2
acetylcholinesterase 2
MMP-2 2
IL-4 2
N-syndecan 2
cryptic 2
substance P 2
p38 2
Lp(a) 2
UDP-GlcNAc 2
atrial natriuretic factor 2
heavy chain 2
DNA polymerase 2
decay-accelerating factor 2
protein C 2
MMP-7 2
MUC2 2
Antithrombin III 2
creatine kinase 2
IGF-I receptor 2
caveolin 1 2
ADP 2
aggrecan 2
factor XII 2
Rho 2
PEG 2
CSA 2
endonuclease 2
JNK 2
neutrophil elastase 2
CCL21 2
adhesion molecule 2
amyloid beta 2
VLDL receptor 2
CBS 2
superoxide dismutase 2
CSB 2
phospholipase 2
keratinocyte growth factor 2
exostosin 2
NDST2 2
Fc receptor 2
CB2 2
extracellular signal-regulated kinase 2
pleiotrophin 2
ECM 2
interleukin-6 2
heat shock protein 90 2
Heparin cofactor II 2
PCI 2
S100A8 2
alpha, beta 2
decorin 2
AKT 2
glutathione S-transferase 2
NGF 2
complement factor H 2
serine protease inhibitor 2
urokinase plasminogen activator 2
epididymal 2
amylase 2
erbB-2 2
angiotensin-converting enzyme 2 2
ICAM-1 2
intercellular adhesion molecule-1 2
galactosyltransferase 2
A431 2
glial cell line-derived neurotrophic factor 2
alpha-amylase 2
monocyte chemotactic protein 2
angiogenin 2
GBM 2
interferon gamma 2
transferrin 2
granulocyte 2
N-deacetylase/N-sulfotransferase 2
esterase 2
OST 2
activin 2
extracellular protein 2
spermatozoa 2
Trypsin 2
cyclooxygenase 2
ICAM-3 2
catalase 2
COX-2 2
vascular cell adhesion molecule-1 2
GTP 2
more...
Disease
tumor 37
SDS 33
cancer 29
atherosclerosis 27
Alzheimer's disease 21
plaque 16
carcinoma 13
HIV 12
hepatocellular carcinoma 10
herpes simplex 10
virus infection 9
adenocarcinoma 9
leukemia 8
Adhesion 8
uterus 8
stomatitis 7
melanoma 7
coagulopathy 7
immunodeficiency 7
Blocking 6
breast cancer 6
malaria 6
mastocytoma 6
cytomegalovirus 6
hepatitis C 6
infectious diseases 5
multiple myeloma 5
glioblastoma 5
thrombocytopenia 5
Aujeszky's disease 5
fibrosarcoma 5
HDL3 4
MCF 4
Infection 4
colon cancer 4
neuroblastoma 4
anemia 4
diabetes 4
proteinuria 4
Chlamydia 4
ischemia 4
sepsis 4
dengue 4
deep vein thrombosis 4
sepsis 4
hepatitis B 4
hemorrhagic fever 3
hyperlipoproteinemia 3
disseminated intravascular coagulation 3
Hurler 3
myeloid leukemia 3
SMC 3
lymphoma 3
cirrhosis 3
Dissociation 3
cystic fibrosis 3
tumor growth 3
PNS 3
pancreatic cancer 3
AIDS 3
arteriosclerosis 2
arthritis 2
HEP 2
mastitis 2
idiopathic pulmonary fibrosis 2
glioma 2
vaccinia 2
metastases 2
coxsackievirus 2
mastocytosis 2
hepatitis E 2
Lyme disease 2
nephrotic syndrome 2
SARS 2
Ross River 2
IVA 2
Human immunodeficiency virus type 2
glioblastoma multiforme 2
liver disease 2
macular degeneration 2
carcinogenesis 2
embryonal carcinoma 2
Japanese encephalitis 2
CSB 2
CSB 2
CSA 2
Still 2
pulmonary embolism 2
SEM 2
renal failure 2
osteosarcoma 2
hepatitis 2
sarcoma 2
mole 2
blindness 2
Kaposi's sarcoma 2
Thrombus 2
mole 2
leptospirosis 2
systemic lupus erythematosus 2
glaucoma 2
nephrosis 2
intraocular pressure 2
lupus nephritis 2
cold 2
SCID 1
glomerulopathy 1
acute monocytic leukemia 1
inflammatory bowel disease 1
aqueous humor 1
tumorigenesis 1
RSV infection 1
nephritis 1
PBD 1
anterior uveitis 1
acute promyelocytic leukemia 1
dementia 1
hypofibrinogenemia 1
Infections 1
vascular disease 1
interstitial cystitis 1
West 1
Osteopathia striata with cranial sclerosis 1
thrombophlebitis 1
acute myeloid leukemia 1
disc degeneration 1
bacterial infection 1
HOS 1
transitional cell carcinoma of the bladder 1
tic 1
cornea 1
mental retardation 1
MLC 1
amyloidosis 1
Foot-and-mouth disease 1
preeclampsia 1
rhinitis 1
ABL 1
gonococcal 1
liposarcoma 1
aseptic meningitis 1
aplastic anemia 1
Dementia with Lewy bodies 1
viremia 1
visual dysfunction 1
primary sclerosing cholangitis 1
adenoma 1
APC 1
tumor angiogenesis 1
circulating anticoagulants 1
keratoconjunctivitis 1
Burkitt's lymphoma 1
mouth disease 1
Epithelioma 1
cervical cancer 1
SHS 1
endometrial cancer 1
Hodgkin's disease 1
Hymenolepis 1
haemophilia 1
depression 1
hepatoblastoma 1
spotted fever 1
scrapie 1
status epilepticus 1
NAME 1
mucopolysaccharidosis 1
MPS II 1
Adenovirus 1
acute renal failure 1
epithelioma 1
Proteus 1
CSE 1
kidney tumor 1
Classical swine fever 1
NS3 1
primary biliary cirrhosis 1
TEM 1
Plaque 1
hypercalciuria 1
diabetic ulcer 1
Bartter's syndrome 1
leukopenia 1
human papilloma virus 1
heart disease 1
AGA 1
Wiskott-Aldrich syndrome 1
TEM 1
osteoarthritis 1
heart failure 1
stroke 1
achondroplasia 1
EDA 1
cardiomyopathy 1
human papilloma virus 1
ICD 1
encephalitis 1
Franklin 1
cognitive impairment 1
type 1 diabetes 1
worms 1
type 2 diabetes 1
SHS 1
chondrosarcoma 1
Yersinia 1
Mycobacterium 1
coronary artery disease 1
rickettsiosis 1
AL amyloidosis 1
diabetic nephropathy 1
necrotizing enterocolitis 1
Haemophilus 1
gastroenteritis 1
tumor progression 1
zoonosis 1
Teratocarcinoma 1
acute myocardial infarction 1
Heparin-induced thrombocytopenia 1
endocarditis 1
progressive supranuclear palsy 1
MPS I 1
seminal vesicles 1
chronic bronchitis 1
MPS IIIA 1
hemolytic uremic syndrome 1
hyperglycemia 1
pituitary tumor 1
Epstein 1
nephrocalcinosis 1
Placenta 1
laryngotracheitis 1
Sanfilippo 1
Haemophilia 1
venous stasis 1
spongiform encephalopathy 1
pulmonary fibrosis 1
MIP 1
PAA 1
Tic 1
Rift Valley fever 1
rheumatoid arthritis 1
epithelial ovarian cancer 1
Marek's disease 1
atherosclerotic cardiovascular disease 1
PSA 1
chronic liver disease 1
endometrial adenocarcinoma 1
DMAT 1
rhabdomyosarcoma 1
brain edema 1
Evans 1
Myometrium 1
otitis media 1
systemic candidiasis 1
diphtheria 1
leprosy 1
degenerative disc disease 1
epidermolysis bullosa 1
colitis 1
tracheobronchitis 1
tuberculosis 1
Brown 1
chronic myeloid leukemia 1
cardiovascular disease 1
myocardial ischemia 1
influenza 1
measles 1
lysosomal storage disease 1
mental retardation 1
antiphospholipid syndrome 1
middle ear 1
squamous cell carcinoma 1
erythroleukemia 1
pasteurellosis 1
urticaria pigmentosa 1
EMD 1
Symptom
hypothermia 4
diarrhea 1
analgesia 1
collapse 1
seizures 1
acidity 1
pain 1
Stiffness 1
hypercapnia 1
anesthesia 1
hyperoxia 1
flushing 1
Drug
ABC 153
lysine 25
Pronase 10
Gel 6
ACT 5
Cardiovasc 5
LMWH 4
Dermatol 4
IFN-gamma 4
Protamine sulfate 3
Hyaluronidase 3
Antithrombin III 3
Hyaluronidase 3
MRC 2
MgSO4 2
Fluorescein 2
CSF 2
ascorbate 2
CaCl2 2
CaCl2 2
Papain 2
Lovenox 2
CaCl2 2
Dalteparin 2
Ringer's solution 1
CTX 1
Lovastatin 1
Biopolymers 1
Fluorescein 1
Alanine 1
IL-2 1
FAD 1
TAT 1
NAG 1
Triad 1
IPD 1
balanced salt solution 1
ENT 1
Orgaran 1
Fraction 1
Histamine 1
Fragment 1
Dextran sulfate sodium 1
Gleevec 1
Coumadin 1
Cellulose acetate 1
Imatinib 1
EE2 1
Orlistat 1
ROC 1
FLM 1
Abciximab 1
APM 1
DNase I 1
nitroglycerin 1
ROS 1
Leaf 1
Chlorate 1
Meth 1
Argatroban 1
HCH 1
Sinemet 1
RSM 1
Enzyme
heparinase 1270
hyaluronidase 227
chondroitinase 195
chondroitinase 194
hyaluronidase 84
thrombin 68
thromboplastin 54
trypsin 53
neuraminidase 51
chondroitinase AC 39
heparitinase I 29
lipoprotein lipase 28
chondroitin ABC lyase 21
collagenase 20
ERK 17
endo-beta-galactosidase 14
plasmin 11
protein kinase C 11
mitogen-activated protein kinase 11
phospholipase C 11
lipase 10
papain 9
tissue plasminogen activator 9
urokinase-type plasminogen activator 8
chondroitinase B 8
proteinase K 7
protein kinase 7
reverse transcriptase 7
DNase 6
alkaline phosphatase 6
phospholipase A2 6
endo-beta-galactosidase 6
peroxidase 6
furin 5
focal adhesion kinase 5
glutathione S-transferase 5
sialidase 4
PNGase F 4
ACS 4
kallikrein 4
sulfatase 4
glycuronidase 4
luciferase 3
LPL 3
creatine kinase 3
APC 3
phosphatidylinositol 3-kinase 3
deoxyribonuclease 3
chymotrypsin 3
beta-lactamase 3
MMP 3
lysozyme 3
deoxyribonuclease 3
alginate lyase 3
ATPase 3
neutrophil elastase 3
catalase 3
chymase 3
hyaluronate lyase 3
superoxide dismutase 3
RNA polymerase 2
glucosaminyl 3-O-sulfotransferase 2
subtilisin 2
endonuclease 2
RNase 2
glucosaminyl 3-O-sulfotransferase 2
UDP-glucose dehydrogenase 2
DNA polymerase 2
xanthine oxidase 2
alpha-amylase 2
GSK 2
endo-N 2
bilirubin oxidase 2
elastase 2
acetylcholinesterase 2
pectate lyase 2
tryptase 2
proprotein convertase 2
beta-galactosidase 2
PNL 1
chondroitin 6-sulfotransferase 1
thymidine kinase 1
dihydrofolate reductase 1
MAT 1
GPI-specific phospholipase C 1
transcriptase 1
guanylate cyclase 1
MEK 1
interstitial collagenase 1
C3b inactivator 1
RNase 1
protein phosphatase 2A 1
dextranase 1
pyruvate carboxylase 1
cholesterol esterase 1
pregnancy-associated plasma protein-A 1
beta-glucuronidase 1
oligogalacturonate lyase 1
benzoylformate decarboxylase 1
dipeptidyl peptidase IV 1
DNase II 1
apyrase 1
TAT 1
PATE 1
ADPase 1
cathepsin D 1
histone acetyltransferase 1
ribonuclease 1
ceruloplasmin 1
glucose-6-phosphatase 1
cellulase 1
NO synthase 1
phosphodiesterase 1
myosin light chain kinase 1
prostate-specific antigen 1
MAT 1
chitinase 1
TSR 1
urease 1
PI-PLC 1
lipoxygenase 1
granzyme B 1
endoglycosidase H 1
hexokinase 1
5'-nucleotidase 1
CPA2 1
pepsin 1
MMP-3 1
D-glucuronyl C-5 epimerase 1
ribonuclease 1
lysophospholipase D 1
acid phosphatase 1
HIV-1 protease 1
matrix metalloproteinase 2 1
histidine decarboxylase 1
transglutaminase 1
NAD glycohydrolase 1
chondro-6-sulfatase 1
ATP synthase 1
glyceraldehyde-3-phosphate dehydrogenase 1
lysin 1
sphingosine kinase 1
gamma-glutamyl transpeptidase 1
ficin 1
clostripain 1
chondro-4-sulfatase 1
HCS 1
Hageman factor 1
cholinesterase 1
angiotensin-converting enzyme 2 1
MIP 1
CD13 1
choline acetyltransferase 1
phosphatidylinositol phospholipase C 1
urease 1
Compound
sulfate 607
Heparin 135
sodium 98
Dec 96
hyaluronic acid 54
Clin 51
Heparan sulfate 49
nitrous acid 47
DNA 40
calcium 36
SDS 35
lysine 32
arginine 32
GlcNAc 32
DEAE 32
acetate 31
salt 26
galactose 19
phosphate 19
cysteine 19
His 18
keratan sulfate 18
serine 17
water 16
EDTA 16
EDTA 16
iduronate 15
GalNAc 13
tyrosine 12
glucose 12
nitric oxide 11
methionine 10
alanine 10
bromide 10
zinc 9
D-glucuronic acid 9
leucine 9
guanidine 9
D-glucosamine 9
Asp 8
Triton X-100 8
methanol 8
Gly 8
HCl 8
iron 8
Polybrene 7
ethanol 7
oxygen 7
ammonium 7
silver 7
Chondroitin sulfate 6
THP 6
hexuronic acid 6
NH2 6
Chondroitin 6
urea 6
hexuronic acid 6
hexuronic acid 6
THP 6
TEG 6
Protamine 6
hexuronic acid 6
PEG 5
hydrogen 5
Nitrite 5
Phe 5
TNF 5
ATP 5
Thrombin 5
glutamic acid 5
nickel 5
ACS 4
proline 4
hydroxylamine 4
PEG 4
barium 4
Suramin 4
acrylamide 4
cobalt 4
copper 4
sulfuric acid 4
ACS 4
xylose 4
hydroxylamine 4
Optimal 4
Toluidine blue 4
COS 4
creatinine 3
Ruthenium 3
acetonitrile 3
cAMP 3
TCA 3
formaldehyde 3
UGA 3
Glucosamine 3
MIA 3
MDA 3
Sodium chlorate 3
hexose 3
Azure A 3
asparagine 3
Ruthenium 3
Dermatan sulfate 3
ADP 3
hydroxide 3
acetic acid 3
chloroform 3
retinoic acid 3
APS 3
threonine 3
TOF 3
Salt 3
formaldehyde 3
formic acid 2
glutamate 2
Dextran 2
2-mercaptoethanol 2
cGMP 2
tryptophan 2
potassium 2
Sucrose 2
Tris 2
iodine 2
aspartic acid 2
sodium chloride 2
formic acid 2
MgCl2 2
DTT 2
CAA 2
formic acid 2
CBS 2
Tris 2
chromium 2
formic acid 2
Cereb 2
CaCl2 2
CO2 2
ADP 2
DTT 2
formic acid 2
GTP 2
Guo 2
C-3 2
ADP 2
prostacyclin 2
Insulin 2
Collagen 2
Dermatan sulfate 2
Guo 2
formic acid 2
pyridine 2
TEM 2
formic acid 2
N-acetyl-D-glucosamine 2
aspartic acid 2
Mg2+ 2
formic acid 2
aspartic acid 2
manganese 2
ACh 2
formic acid 2
formic acid 2
octyl 2
octyl 2
Cysteine 2
Ruthenium red 2
Cholesterol 2
ASA 2
aspartic acid 2
HEP 2
Agarose 2
Plasmin 2
phenol 2
PAS 2
octyl 2
Trypsin 2
UDP-GlcNAc 2
Phenylalanine 1
Purine 1
PBD 1
pyrrolidine 1
CPA 1
Eosin 1
PAM 1
Congo red 1
Abbott 1
aldosterone 1
Polyamine 1
Nitro-L-arginine 1
Ionophore A23187 1
benzo[ghi]perylene 1
NTA 1
CAT 1
aldehyde 1
CPB 1
ammonia 1
BLM 1
superoxide radical 1
ABL 1
PMA 1
DTPA 1
CAT 1
ClO 1
Tween 80 1
Acetone 1
HBr 1
pyrrolidine 1
PLA 1
acetone 1
sebacic acid 1
hexanoic acid 1
DMF 1
MEK 1
ANA 1
Organon 1
2-naphthol 1
oxalate 1
ornithine 1
sebacic acid 1
Staurosporine 1
Chlorate 1
Serine 1
hexose 1
sebacic acid 1
CPA 1
ornithine 1
SPM 1
PAR 1
CPA 1
butyric acid 1
H2O2 1
Wortmannin 1
Triton 1
CAT 1
IAA 1
cadmium 1
ornithine 1
FAD 1
anthracene 1
IPD 1
IBT 1
Phorbol 12-myristate 13-acetate 1
Estrogen 1
aminomethyl 1
ACI 1
Mannose 1
Cytochalasin D 1
butyric acid 1
DDA 1
acrylic acid 1
ornithine 1
Warfarin 1
SHS 1
tryptophan 1
CPA 1
Pentobarbital 1
hexanoic acid 1
Chlorate 1
hexose 1
DAPT 1
Thyroid 1
vitamin D 1
hydrazine 1
SO3 1
Argatroban 1
aldehyde 1
Cellulose 1
NO3 1
butyric acid 1
Adenosine 1
vinyl 1
Alanine 1
methane 1
CE 2 1
DIC 1
naphthalene 1
PGD2 1
H2S 1
PMA 1
FK506 1
2-naphthol 1
Bradykinin 1
IAA 1
BaCl2 1
glycerol 1
Isoform 1
Pentobarbital 1
2-naphthyl 1
Choline 1
L-Cysteic acid 1
PGE 1
Tunicamycin 1
Estrogen 1
Dexamethasone 1
DDA 1
pentose 1
PAA 1
Staurosporine 1
myristic acid 1
ANA 1
cyanamide 1
DDA 1
ornithine 1
Eosin 1
PAM 1
FDP 1
Factor H 1
mercury 1
Thapsigargin 1
UDP 1
GRG 1
myristic acid 1
Histamine 1
2-naphthol 1
Collagenase 1
CTX 1
nitrate 1
Naloxone 1
BCR 1
C16H14 1
more...