Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.2.2.7 (heparinase)
 1,270 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chondroitinase 194
ABC 153
proteoglycan 105
Sep 92
heparan sulfate proteoglycan 88
hyaluronidase 84
glucosamine 77
thrombin 67
antithrombin III 58
fibronectin 48
neuraminidase 47
Mol 46
glycoprotein 45
collagen 44
NMR 42
antithrombin 41
syndecan 36
thromboplastin 34
SDS 33
lipoprotein lipase 28
core protein 26
LDL receptor 26
FGF 22
factor Xa 22
mast cell 22
collagenase 20
apolipoprotein E 20
heparanase 19
fibrinogen 19
apoE 19
apolipoprotein 18
prothrombin 17
perlecan 17
Lipoprotein lipase 16
lactoferrin 16
cytokine 16
albumin 15
platelet factor 4 15
ferritin 14
lipoprotein receptor-related protein 14
vascular endothelium 14
beta 1 13
PLA 13
lectin 13
FGF-2 12
membrane-bound 12
Chondroitinase 12
FGF receptor 12
bFGF 11
tyrosine kinase 11
mucin 11
vascular endothelial growth factor 11
heparin cofactor II 11
HSPG 10
polypeptide 10
sulfotransferase 10
glypican 10
tumor necrosis factor 9
chemokine 9
hepatic lipase 9
hepatocyte growth factor 8
epidermal growth factor 8
galactosamine 8
hemoglobin 8
plasminogen 8
vitronectin 8
amyloid precursor protein 8
Gen 8
envelope glycoprotein 8
insulin 7
Neuraminidase 7
Glypican-3 7
lymphoid 7
platelet-derived growth factor 7
envelope protein 7
membrane protein 7
ESI 7
gut 6
histone 6
delta 4 6
urokinase-type plasminogen activator 6
PI3K 6
heparin-binding protein 6
binding peptide 6
CD44 6
Antithrombin 6
low-density lipoprotein receptor 6
tissue plasminogen activator 6
tissue factor 6
cell surface receptor 6
lipase 6
VEGF 6
THP 6
L-selectin 5
TNF-alpha 5
fused 5
alkaline phosphatase 5
ERK 5
thrombospondin 5
LRP 5
ATP 5
FGFR1 5
TNF 5
tissue factor pathway inhibitor 5
prion 5
EGF receptor 5
transforming growth factor-beta 5
Apolipoprotein E 5
lipopolysaccharide 5
ACT 5
IL-8 5
HDL 5
mer 4
Met 4
CXCL12 4
MAPK 4
serum albumin 4
sulfatase 4
heparin-binding EGF-like growth factor 4
IFN-gamma 4
metalloproteinase 4
IGFBP-5 4
heparin binding protein 4
low density lipoprotein receptor 4
HVEM 4
TGF-beta 4
Heparanase 4
vascular endothelial growth factor receptor 2 4
ACS 4
Pseudomonas 4
CD4 4
bradykinin 4
Gal 4
nectin-1 4
FGF2 4
GST 4
kallikrein 4
N-glycanase 4
beta-actin 4
Platelet factor 4 4
matrix metalloproteinase 4
angiotensin II 4
thymus 4
alpha-L-fucosidase 4
fur 4
protease inhibitor 4
P-selectin 4
RANTES 4
axonal 4
serine protease 4
sialidase 4
Fibroblast growth factor 4
precursor protein 4
myosin 4
LPS 4
deoxyribonuclease 3
TBM 3
phosphatidylinositol-specific 3
receptor tyrosine kinase 3
Glypican-1 3
more...
Disease
tumor 37
SDS 33
cancer 29
atherosclerosis 27
Alzheimer's disease 21
plaque 16
carcinoma 13
HIV 12
hepatocellular carcinoma 10
herpes simplex 10
adenocarcinoma 9
virus infection 9
leukemia 8
uterus 8
Adhesion 8
stomatitis 7
melanoma 7
coagulopathy 7
immunodeficiency 7
hepatitis C 6
cytomegalovirus 6
breast cancer 6
Blocking 6
mastocytoma 6
malaria 6
Aujeszky's disease 5
multiple myeloma 5
fibrosarcoma 5
glioblastoma 5
thrombocytopenia 5
infectious diseases 5
hepatitis B 4
deep vein thrombosis 4
Chlamydia 4
anemia 4
neuroblastoma 4
dengue 4
proteinuria 4
ischemia 4
diabetes 4
sepsis 4
sepsis 4
MCF 4
HDL3 4
colon cancer 4
Infection 4
pancreatic cancer 3
AIDS 3
hyperlipoproteinemia 3
disseminated intravascular coagulation 3
SMC 3
cirrhosis 3
Dissociation 3
lymphoma 3
tumor growth 3
cystic fibrosis 3
hemorrhagic fever 3
myeloid leukemia 3
Hurler 3
PNS 3
mole 2
Thrombus 2
CSA 2
HEP 2
idiopathic pulmonary fibrosis 2
glioma 2
vaccinia 2
mastitis 2
coxsackievirus 2
pulmonary embolism 2
Lyme disease 2
nephrotic syndrome 2
mole 2
glioblastoma multiforme 2
glaucoma 2
carcinogenesis 2
macular degeneration 2
SARS 2
liver disease 2
Ross River 2
IVA 2
hepatitis E 2
renal failure 2
embryonal carcinoma 2
CSB 2
cold 2
metastases 2
leptospirosis 2
hepatitis 2
arthritis 2
SEM 2
intraocular pressure 2
CSB 2
Still 2
osteosarcoma 2
sarcoma 2
Japanese encephalitis 2
blindness 2
Kaposi's sarcoma 2
Human immunodeficiency virus type 2
mastocytosis 2
arteriosclerosis 2
systemic lupus erythematosus 2
nephrosis 2
lupus nephritis 2
Osteopathia striata with cranial sclerosis 1
inflammatory bowel disease 1
HOS 1
cardiovascular disease 1
tumorigenesis 1
influenza 1
cornea 1
PBD 1
anterior uveitis 1
dementia 1
hypofibrinogenemia 1
Infections 1
vascular disease 1
interstitial cystitis 1
West 1
mental retardation 1
MLC 1
amyloidosis 1
Foot-and-mouth disease 1
preeclampsia 1
rhinitis 1
ABL 1
gonococcal 1
degenerative disc disease 1
disc degeneration 1
myocardial ischemia 1
Epithelioma 1
SHS 1
Dementia with Lewy bodies 1
depression 1
hepatoblastoma 1
primary sclerosing cholangitis 1
adenoma 1
liposarcoma 1
scrapie 1
Burkitt's lymphoma 1
Hodgkin's disease 1
Hymenolepis 1
aseptic meningitis 1
Adenovirus 1
Classical swine fever 1
CSE 1
epithelioma 1
tumor angiogenesis 1
circulating anticoagulants 1
Bartter's syndrome 1
hypercalciuria 1
NS3 1
leukopenia 1
human papilloma virus 1
AGA 1
osteoarthritis 1
achondroplasia 1
EDA 1
human papilloma virus 1
more...
Symptom
hypothermia 4
diarrhea 1
analgesia 1
collapse 1
seizures 1
acidity 1
pain 1
Stiffness 1
hypercapnia 1
anesthesia 1
hyperoxia 1
flushing 1
Drug
ABC 153
lysine 25
Pronase 10
Gel 6
ACT 5
Cardiovasc 5
LMWH 4
Dermatol 4
IFN-gamma 4
Protamine sulfate 3
Hyaluronidase 3
Antithrombin III 3
Hyaluronidase 3
MRC 2
MgSO4 2
Fluorescein 2
CSF 2
ascorbate 2
CaCl2 2
CaCl2 2
Papain 2
Lovenox 2
CaCl2 2
Dalteparin 2
Ringer's solution 1
CTX 1
Lovastatin 1
Biopolymers 1
Fluorescein 1
Alanine 1
IL-2 1
FAD 1
TAT 1
NAG 1
Triad 1
IPD 1
balanced salt solution 1
ENT 1
Orgaran 1
Fraction 1
Histamine 1
Fragment 1
Dextran sulfate sodium 1
Gleevec 1
Coumadin 1
Cellulose acetate 1
Imatinib 1
EE2 1
Orlistat 1
ROC 1
FLM 1
Abciximab 1
APM 1
DNase I 1
nitroglycerin 1
ROS 1
Leaf 1
Chlorate 1
Meth 1
Argatroban 1
HCH 1
Sinemet 1
RSM 1
Enzyme
heparinase 1270
hyaluronidase 227
chondroitinase 195
chondroitinase 194
hyaluronidase 84
thrombin 68
thromboplastin 54
trypsin 53
neuraminidase 51
chondroitinase AC 39
heparitinase I 29
lipoprotein lipase 28
chondroitin ABC lyase 21
collagenase 20
ERK 17
endo-beta-galactosidase 14
plasmin 11
protein kinase C 11
mitogen-activated protein kinase 11
phospholipase C 11
lipase 10
papain 9
tissue plasminogen activator 9
urokinase-type plasminogen activator 8
chondroitinase B 8
proteinase K 7
protein kinase 7
reverse transcriptase 7
DNase 6
alkaline phosphatase 6
phospholipase A2 6
endo-beta-galactosidase 6
peroxidase 6
furin 5
focal adhesion kinase 5
glutathione S-transferase 5
sialidase 4
PNGase F 4
ACS 4
kallikrein 4
sulfatase 4
glycuronidase 4
luciferase 3
LPL 3
creatine kinase 3
APC 3
phosphatidylinositol 3-kinase 3
deoxyribonuclease 3
chymotrypsin 3
beta-lactamase 3
MMP 3
lysozyme 3
deoxyribonuclease 3
alginate lyase 3
ATPase 3
neutrophil elastase 3
catalase 3
chymase 3
hyaluronate lyase 3
superoxide dismutase 3
RNA polymerase 2
glucosaminyl 3-O-sulfotransferase 2
subtilisin 2
endonuclease 2
RNase 2
glucosaminyl 3-O-sulfotransferase 2
UDP-glucose dehydrogenase 2
DNA polymerase 2
xanthine oxidase 2
alpha-amylase 2
GSK 2
endo-N 2
bilirubin oxidase 2
elastase 2
acetylcholinesterase 2
pectate lyase 2
tryptase 2
proprotein convertase 2
beta-galactosidase 2
PNL 1
chondroitin 6-sulfotransferase 1
thymidine kinase 1
dihydrofolate reductase 1
MAT 1
GPI-specific phospholipase C 1
transcriptase 1
guanylate cyclase 1
MEK 1
interstitial collagenase 1
C3b inactivator 1
RNase 1
protein phosphatase 2A 1
dextranase 1
pyruvate carboxylase 1
cholesterol esterase 1
pregnancy-associated plasma protein-A 1
beta-glucuronidase 1
oligogalacturonate lyase 1
benzoylformate decarboxylase 1
dipeptidyl peptidase IV 1
DNase II 1
apyrase 1
TAT 1
PATE 1
ADPase 1
cathepsin D 1
histone acetyltransferase 1
ribonuclease 1
ceruloplasmin 1
glucose-6-phosphatase 1
cellulase 1
NO synthase 1
phosphodiesterase 1
myosin light chain kinase 1
prostate-specific antigen 1
MAT 1
chitinase 1
TSR 1
urease 1
PI-PLC 1
lipoxygenase 1
granzyme B 1
endoglycosidase H 1
hexokinase 1
5'-nucleotidase 1
CPA2 1
pepsin 1
MMP-3 1
D-glucuronyl C-5 epimerase 1
ribonuclease 1
lysophospholipase D 1
acid phosphatase 1
HIV-1 protease 1
matrix metalloproteinase 2 1
histidine decarboxylase 1
transglutaminase 1
NAD glycohydrolase 1
chondro-6-sulfatase 1
ATP synthase 1
glyceraldehyde-3-phosphate dehydrogenase 1
lysin 1
sphingosine kinase 1
gamma-glutamyl transpeptidase 1
ficin 1
clostripain 1
chondro-4-sulfatase 1
HCS 1
Hageman factor 1
cholinesterase 1
angiotensin-converting enzyme 2 1
MIP 1
CD13 1
choline acetyltransferase 1
phosphatidylinositol phospholipase C 1
urease 1
Compound
sulfate 607
Heparin 135
sodium 98
Dec 96
hyaluronic acid 54
Clin 51
Heparan sulfate 49
nitrous acid 47
DNA 40
calcium 36
SDS 35
GlcNAc 32
arginine 32
lysine 32
DEAE 32
acetate 31
salt 26
phosphate 19
cysteine 19
galactose 19
keratan sulfate 18
His 18
serine 17
EDTA 16
water 16
EDTA 16
iduronate 15
GalNAc 13
glucose 12
tyrosine 12
nitric oxide 11
bromide 10
alanine 10
methionine 10
D-glucuronic acid 9
zinc 9
leucine 9
guanidine 9
D-glucosamine 9
Gly 8
iron 8
Triton X-100 8
methanol 8
HCl 8
Asp 8
oxygen 7
ethanol 7
Polybrene 7
silver 7
ammonium 7
Protamine 6
THP 6
THP 6
hexuronic acid 6
Chondroitin 6
TEG 6
urea 6
hexuronic acid 6
NH2 6
hexuronic acid 6
hexuronic acid 6
Chondroitin sulfate 6
PEG 5
Phe 5
glutamic acid 5
nickel 5
Thrombin 5
Nitrite 5
ATP 5
hydrogen 5
TNF 5
ACS 4
sulfuric acid 4
proline 4
COS 4
hydroxylamine 4
PEG 4
barium 4
Toluidine blue 4
Suramin 4
xylose 4
cobalt 4
copper 4
ACS 4
Optimal 4
hydroxylamine 4
acrylamide 4
creatinine 3
Ruthenium 3
retinoic acid 3
chloroform 3
UGA 3
Glucosamine 3
Sodium chlorate 3
formaldehyde 3
hydroxide 3
asparagine 3
TCA 3
cAMP 3
Azure A 3
threonine 3
Dermatan sulfate 3
ADP 3
formaldehyde 3
Ruthenium 3
acetonitrile 3
Salt 3
APS 3
hexose 3
MIA 3
acetic acid 3
TOF 3
MDA 3
aspartic acid 2
2-mercaptoethanol 2
glutamate 2
DTT 2
prostacyclin 2
Collagen 2
Guo 2
cGMP 2
ACh 2
formic acid 2
potassium 2
Trypsin 2
formic acid 2
UDP-GlcNAc 2
Tris 2
ASA 2
aspartic acid 2
Dextran 2
aspartic acid 2
Insulin 2
Plasmin 2
HEP 2
Agarose 2
Cysteine 2
DTT 2
Ruthenium red 2
CBS 2
formic acid 2
formic acid 2
chromium 2
formic acid 2
aspartic acid 2
Cholesterol 2
CaCl2 2
CO2 2
ADP 2
pyridine 2
formic acid 2
formic acid 2
Guo 2
ADP 2
N-acetyl-D-glucosamine 2
Dermatan sulfate 2
tryptophan 2
C-3 2
TEM 2
GTP 2
more...