Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.2.2.7 (
heparinase
)
1,270
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Artifactual heparin contamination of blood samples drawn for coagulation testing is an ongoing problem. A retrospective analysis of activated partial thromboplastin times (APTTs) greater than 45 seconds from patients on neither heparin nor
Coumadin
(Dupont, Wilmington, DE) therapy shows complete correction of the APTT to normal in 39% of such samples after treatment with
heparinase
. Recheck of samples with significantly prolonged APTTs after treatment with
heparinase
is proposed as the best method to avoid inappropriate transfusion of fresh frozen plasma.
...
PMID:Heparin contamination in coagulation testing and a protocol to avoid it and the risk of inappropriate FFP transfusion. 757 96
