Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.2.2.10 (
PNL
)
341
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Aspergillus niger pectin lyases are encoded by a multigene family. The complete nucleotide sequence of the
pectin lyase
PLA
-encoding gene pelA has been determined. Comparison of the deduced amino acid sequence with the deduced amino acid sequence of the other characterized
pectin lyase
, PLD, shows that the proteins share 69% amino acid identity. When grown on media with pectin as the sole carbon source, A. niger transformants containing multiple copies of the pelA gene show raised mRNA levels and overexpression of the gene product
PLA
compared with the wild-type strain.
PLA
was purified and characterized. In A. nidulans transformants
PLA
is also produced in medium containing a high concentration of glucose and no pectin.
...
PMID:Structure of the Aspergillus niger pelA gene and its expression in Aspergillus niger and Aspergillus nidulans. 193 34
