Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:4.2.2.10 (PNL)
 341 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The management of renal calculi following previous open surgery represents a challenge for urologists. The aim of this study is to evaluate the outcomes and safety of ureteroscopic laser retrograde intrarenal surgery (RIRS) for renal calculi following prior open renal surgery. The charts of 53 patients who underwent RIRS for renal calculi following prior open surgery for urolithiasis were reviewed. Both flexible and semi-rigid ureteroscopes were utilized together with holmium: YAG laser for stone disintegration. Intravenous urography, computed tomography (CT) and ultrasound were used to evaluate the patient, perioperatively. Stone size ranged from 5 to 32 mm (mean 14.3 mm). The mean operative time was 86 min (20-130). The overall stone-free rate was 92.4%. The overall stone-free rates after one and two-procedures were 79.2% (42 cases) and 92.4% (49 cases), respectively. Four patients (7.5%) had larger residual fragments, 2 (3.8%) of them underwent SWL, and 2 (3.8%) cases were followed up conservatively. Major complications were reported in two patients (3.8%). Stone analysis revealed calcium oxalate in 39 patients, uric acid in 5, calcium phosphate in 4, struvite in 3, and cystine in 2 cases. Ureteroscopic retrograde intrarenal surgery for renal calculi following prior open renal surgery was a minimally invasive, safe procedure with a high success rate. It is a viable alternative for PNL in managing recurrent renal calculi efficiently.
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PMID:Ureteroscopic retrograde intrarenal surgery after previous open renal stone surgery: initial experience. 2205 6

Morbidity of USD is constantly rising in Armenia as well as in the world and this tendency is rising on its own. The prevalence for 100,000 of population has grown from 252,1 in 1990 to 519.6 in 2014. If in 1990 the incidence of USD was 52.6 new cases per 100,000 of population, in 2014 the incidence grew to 196.2 new cases. We have analyzed data of 793 patients, who were examined and treated at "Izmirlyan" Medical Center from 2006 to 2013 with the diagnosis of USD. The stones were removed by a medical expulsion technique as well as surgically by ESWL, URS, PNL, laparoscopy or open surgery. Chemical analysis of stone shows that 49,56% patients had calcium oxalate stones, 7,19% - uric acid stones, 0,76% - carbonate stones, 0,38% - phosphate stones, 0,26% - cystine stone and 41,6% - Mixed stones. The stone distribution by chemical composition in patients from Yerevan is the following: 52,3% - calcium oxalate stones, 5,9% - uric acid stones, 1,05% - carbonate stones, 0,42% - phosphate stones, 40,33% - mixed stones. The stone type largest percentage by regions of Armenia: oxalate stones in Armavir region of Armenia - 58,4%; uric acid stones in Tavush and Sunik regions - 25% and 17,6%; mixed stones in Lori and Vayots-Dzor regions. In conclusion we can say that in a small country like Armenia USD is one of the most widespread diseases with different stone composition, depending on the region, as far as the landscape of the country varies from 380 to 4100 m above sea level and climate ranges from hot subtropical to cold high-land. CaOx stones are seen most frequently throughout Armenia, the percentage of these stone ranged from 31,25% to 58,4%, with a medium value of 49,56%. Next largest group is represented by mixed stones, which mostly consist of CaOx again and uric acid stones, which, of interest, constitutes more stone burden in absolute figures compared to pure uric acid stones.
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PMID:[; RETROSPECTIVE CLINICAL EPIDEMIOLOGICAL STUDY OF PREVALENCE OF URINARY STONE DISEASE IN THE REGIONS OF ARMENIA]. 3296 44