Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.2.1.22 (cystathionine beta-synthase)
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Human Gene/Protein
cystathionine beta-synthase 15.0
phosphoinositide-3-kinase adaptor protein 1 15.0
G protein beta subunit-like protein 14.0
CBS protein 13.8
mitogen-activated protein kinase kinase kinase 9 13.4
alpha-A-crystallin 13.0
cystathionine gamma-lyase 13.0
NRBP2 12.7
Cystathionine gamma-lyase 12.7
nuclear receptor binding protein 2 12.7
KNP1 12.4
FTHFD 12.4
MPST 12.2
transposase-like protein 12.2
CYS1 12.1
TSKS 11.8
CRYA1 11.6
CLC2 11.6
pyridoxal phosphatase 11.4
EXOG 11.4
more...
Disease
CBS deficiency 14.3
homocystinuria 12.5
cystathioninemia 12.4
Carotid artery thrombosis 12.2
hypermethioninemia 11.7
cystathioninuria 11.2
methionine synthase deficiency 11.0
cblF 10.2
hyperhomocysteinemia 10.1
Bateman 9.1
vitamin B6 deficiency 8.8
disorders of amino acid metabolism 8.7
Activated protein C resistance 8.5
folate deficiency 8.3
brittle hair 8.2
X-linked sideroblastic anemia 8.1
SBMA 8.0
Demented 8.0
CSE 7.8
Dent's disease 7.8
more...
Symptom
iridodonesis 10.4
Involuntary Movement 6.3
starvation 3.9
dystonia 3.6
HSA 3.5
hyperoxia 2.7
ataxia 2.6
hepatomegaly 2.5
seizures 1.3
exhaustion 1.3
hypothermia 0.9
tremor 0.8
collapse 0.2
fatigue -0.6
diarrhea -0.8
pain -2.0
Drug
Trifluoromethionine 13.4
O-Acetylserine 11.1
Gly-Tyr-Gly 9.6
pyridoxal phosphate 9.5
L-Ser 8.2
Vitamin B 7.9
Pyridoxal phosphate 7.9
Pyridoxal 7.0
RbCl 6.9
RbCl 6.9
THF 6.3
Antithrombin III 6.0
Digitalis 5.8
Glutathione 5.4
Sodium nitroprusside 5.1
Heme 5.0
Capsicum 4.9
Vitamin B12 4.7
Vitamin K 4.6
Glycyrrhiza 4.5
more...
Enzyme
L-serine hydro-lyase 15.0
beta-pyrazolealanine synthase 15.0
cystathionine beta-synthase 15.0
ODAP synthase 15.0
EC 4.4.1.2 14.0
cysteine synthase 13.8
O-acetyl-L-serine acetate-lyase 13.7
EC 2.1.1.3 13.4
quercetin 3-O-methyltransferase 13.4
serine acetyltransferase 13.1
cystathionine gamma-lyase 12.7
beta-cyanoalanine synthase 12.6
Arabinose-5-phosphate isomerase 12.4
L-serine dehydratase 12.3
cysteine lyase 12.1
cystathionine beta-lyase 11.9
betaine-homocysteine methyltransferase 11.4
homocysteine methyltransferase 11.3
cystathionine gamma-synthase 11.2
homoglutathione synthetase 11.2
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Compound
Homolanthionine 15.0
6,7-dimethoxyquinoxaline 14.0
2-vinylquinoline 14.0
C4H9NO3 12.7
O-acetylserine 12.6
O-acetylserine 12.5
C4H9NO3 12.4
O-acetylserine 12.4
Homocystine 12.2
A 186 11.1
Cystathionine 10.7
Cystathionine 10.7
2,2-dichloroacetamide 10.2
homocysteine 10.1
Homocysteine 10.0
Homocysteine 10.0
S-sulfocysteine 9.9
S-methylcysteine 9.9
Homocysteine thiolactone 9.4
CH3-THF 9.2
more...