Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.2.1.22 (
cystathionine beta-synthase
)
965
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cystathionine beta-synthase
673
cystathionine gamma-lyase
85
Mol
80
methylenetetrahydrofolate reductase
58
Sep
57
methionine synthase
46
CBS
45
reductase
42
GSH
30
B12
27
Cystathionine gamma-lyase
24
ATP
23
SAM
20
CBS protein
19
superoxide dismutase
19
insulin
17
polypeptide
17
methyltransferase
16
methionine synthase reductase
15
5,10-methylenetetrahydrofolate reductase
12
more...
Disease
homocystinuria
167
hyperhomocysteinemia
108
CBS deficiency
60
vascular disease
43
atherosclerosis
37
cardiovascular disease
35
GSH
30
mental retardation
28
mental retardation
27
stroke
24
Alzheimer's disease
19
Down syndrome
19
diabetes
19
hypertension
17
folate deficiency
16
cancer
14
coronary artery disease
14
Mycobacterium
13
malnutrition
13
hypermethioninemia
12
more...
Symptom
starvation
11
seizures
6
dystonia
3
ataxia
3
pain
2
hyperoxia
1
HSA
1
exhaustion
1
hepatomegaly
1
Involuntary Movement
1
diarrhea
1
hypothermia
1
iridodonesis
1
tremor
1
fatigue
1
collapse
1
Drug
pyridoxal phosphate
54
THF
19
lysine
11
Vitamin B
9
Glutathione
7
ascorbate
3
Heme
3
O-Acetylserine
3
Ethanol
3
vitamin E
2
DNase I
2
ROS
2
NADH
2
L-Ser
2
Capsicum
2
ABC
1
Dermatol
1
RbCl
1
Glycyrrhiza
1
Sodium nitroprusside
1
more...
Enzyme
cystathionine beta-synthase
965
cysteine synthase
269
cystathionine gamma-lyase
108
methylenetetrahydrofolate reductase
63
methylenetetrahydrofolate reductase
63
serine acetyltransferase
54
methionine synthase
46
methionine synthase
46
methionine adenosyltransferase
26
tryptophan synthase
22
superoxide dismutase
22
L-serine dehydratase
17
L-serine hydro-lyase
16
glutathione S-transferase
15
methionine synthase reductase
14
homocysteine methyltransferase
13
cystathionine gamma-synthase
13
betaine-homocysteine methyltransferase
13
ATP sulfurylase
13
cystathionine beta-lyase
12
more...
Compound
homocysteine
382
cysteine
314
methionine
236
serine
143
adenosylmethionine
98
H2S
96
phosphate
81
Dec
78
O-acetylserine
73
DNA
63
H2S
58
O-acetylserine
53
O-acetylserine
52
oxygen
45
CBS
45
S-adenosylhomocysteine
43
Cysteine
42
sulfate
42
Homocysteine
41
Homocysteine
41
more...