Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:4.1.99.3 (PRE)
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Human Gene/Protein
photolyase 13.9
WDR87 13.0
epitheliasin 13.0
Epitheliasin 13.0
photolyase-like 13.0
PHR1 11.7
POLR1B 11.2
ZK1 11.2
FBXL21 10.8
FADH2 10.8
Tpr1 10.7
FBXL3 10.6
CRY 10.3
cryptochrome 1 10.2
G-protein coupled receptor protein 10.2
CRY1 10.1
SPF30 10.0
Helicase-like transcription factor 10.0
HPH2 10.0
PIK3C2B 10.0
cryptochrome 2 9.8
XPE 9.7
calcium binding and coiled-coil domain 2 9.7
high mobility group 1 protein 9.7
Sp3 transcription factor 9.6
A. nidulans) 9.6
CRY2 9.5
REDD2 9.4
Micrococcus luteus UV endonuclease 9.4
CPD 9.4
PKE 9.4
DLAD 9.4
adenylosuccinate synthase 9.4
hPR 9.3
damage-specific DNA binding protein 1 9.3
ALT2 9.2
REC1 9.2
GDE1 9.2
DNA repair enzyme 9.1
CHOD 9.1
TRE 9.1
CEBPG 9.0
SIGMAR1 8.9
PREP1 8.9
SET7 8.9
PUB 8.9
PBX2 8.8
BLR1 8.8
DET1 8.8
myeloid zinc finger 1 8.8
CCT1 8.8
RHAU 8.7
HLA-B*5801 8.7
Int6 8.7
NPH1 8.7
Ari 8.7
CCT2 8.7
DEL1 8.7
sigma receptor 8.6
LRP130 8.6
tetratricopeptide repeat protein 8.4
TRN 8.3
CLOCK protein 8.3
excision repair protein 8.2
FAD 8.2
C1 protein 8.1
BCKDH 8.1
RAD1 8.1
MTE 8.1
MED25 8.0
PLP2 8.0
Prolactin receptor 8.0
ung 8.0
Suppressor of cytokine signaling 3 8.0
JAK2 protein 8.0
Z-protein 7.9
MZF1 7.9
Pol protein 7.9
CLOCK 7.8
ELOVL4 7.8
more...
Disease
CHRS 10.6
COND 10.3
BOE 10.1
XPE 9.6
Fowlpox 9.3
pediatric liver cancer 8.6
EBSS 8.5
Polymorphic light eruption 8.4
XP-A 8.2
Shope fibroma 7.8
xeroderma pigmentosum 7.4
trichothiodystrophy 7.1
AN2 6.6
hypo-osmolality 6.5
Choroid 6.4
Choroid 6.4
XPD 6.3
CSB 6.0
HBD 6.0
CSB 5.9
complete paraplegia 5.9
PIE 5.9
rind 5.8
BPP 5.8
RP18 5.8
autoimmune lymphoproliferative syndrome 5.8
NPHP1 5.8
BED 5.8
trance 5.7
keratosis 5.7
XPB 5.6
HIV encephalitis 5.6
Lowe syndrome 5.5
DIN 5.5
DIN 5.5
SCA1 5.4
PER 5.4
Bronchiolitis obliterans 5.4
ABS 5.2
CHR 5.2
CSE 5.2
Parry 5.2
ABS 5.1
HRS 5.1
mononeuritis 5.0
Lower limb 5.0
alcohol withdrawal syndrome 5.0
avian leukosis 5.0
Diaphragm 5.0
ICT 4.9
MTC 4.9
behavior problem 4.9
PPP 4.8
Cockayne syndrome 4.8
McArdle's disease 4.8
Habituation 4.8
separation anxiety 4.8
AIP 4.8
skin cancer 4.7
AIP 4.7
postmenopausal bone loss 4.6
hepatoblastoma 4.6
hermaphroditism 4.6
INS 4.5
keratoacanthoma 4.5
PCS 4.5
ERS 4.5
psychosomatic disorders 4.5
COL2A1 4.5
Medulloblastoma 4.4
amnesia 4.4
tobacco dependence 4.4
Zellweger syndrome 4.4
NLS 4.4
lentigo 4.3
measurable disease 4.3
HDL2 4.3
HDL3 4.3
PCC 4.3
metritis 4.2
more...
Symptom
Psychiatric symptoms 5.7
Halo 5.2
skin damage 5.0
exhaustion 4.4
muscle stiffness 3.8
fatigue 3.7
Neuropathic pain 3.5
bloating 3.3
hunger 3.1
tense 2.9
erythema 2.9
pallor 2.7
overweight 2.5
constipation 2.3
acute pain 2.1
analgesia 2.0
discomfort 1.9
wheezing 1.8
discomfort 1.8
low back pain 1.7
numbness 1.7
hyperoxia 1.7
cachexia 1.6
hypotonia 1.5
sleepiness 1.4
myalgia 1.3
nausea 1.1
anesthesia 1.0
collapse 0.8
nausea and vomiting 0.8
pain 0.6
agitation 0.5
weakness 0.4
stigma 0.3
seizures 0.0
tremor -0.2
diarrhea -0.2
starvation -0.6
dyspnea -0.8
headache -0.8
Drug
Posilac 8.7
FAD 8.2
Trilostane 7.2
Lutalyse 7.1
FSH-beta 7.0
FSH-beta 7.0
FSH-beta 6.7
Escitalopram 6.1
GNA 5.9
Pregnenolone 5.8
Flavin 5.6
CTT 5.3
Finasteride 5.2
Gabapentin 5.2
MTC 5.0
Sinemet 4.9
Orphan 4.9
Donepezil 4.9
GHRP 4.9
TES 4.9
NBT 4.6
Camp 4.5
OTC 4.5
PMEA 4.5
Bupivacaine 4.4
DEX 4.2
Sodium nitroprusside 4.1
-deoxyadenosine 4.0
OTC 4.0
DMI 4.0
Fragment 3.8
DNase I 3.8
Horizon 3.8
Fentanyl 3.7
IL-1ra 3.6
Prednisolone 3.5
Growth hormone 3.5
Growth hormone 3.4
balanced salt solution 3.4
MAP 3.4
ADM 3.4
Triclosan 3.4
PTC 3.2
ABC 3.2
Posture 3.2
PCP 3.2
Parkin 3.2
Parkin 3.1
Bifidobacterium 3.1
Glycerol 2.8
CDP 2.8
AZT 2.6
caffeine 2.6
ALA 2.6
CTX 2.6
CTX 2.5
CAM 2.5
Mutagen 2.5
AZT 2.4
Vitamin E 2.3
Kenyan 2.2
EE2 2.1
THF 2.0
NADH 1.9
Albumin 1.8
CTX 1.7
lactose 1.6
IL-2 1.5
Asn 1.5
Gel 1.2
ROC 1.1
Biopolymers 1.0
vitamin E 0.9
Nephron 0.9
ROS 0.8
IFN-gamma 0.8
lysine 0.8
citric acid 0.7
Leaf 0.6
Dermatol 0.3
more...
Enzyme
PRE 14.0
N-methylglutamate synthase 13.0
HY2 8.8
deoxyribonuclease 8.0
endonuclease V 7.8
DNA ligase 7.8
DNA ligase 7.8
chorismate synthase 7.6
AP lyase 7.1
hydroxynitrile lyase 7.0
hydroxynitrile lyase 7.0
endodeoxyribonuclease 6.9
hydroxynitrile lyase 6.8
protochlorophyllide oxidoreductase 6.7
adenylosuccinate synthetase 6.3
venom phosphodiesterase 6.2
cytochrome c peroxidase 6.2
tannase 5.9
LIS 5.8
phospholipid hydroperoxide glutathione peroxidase 5.6
branched-chain alpha-keto acid dehydrogenase 5.4
3'-exonuclease 5.4
PST 5.3
DNase II 5.3
Protein 2 5.3
tyrosine aminotransferase 5.2
CGT 5.2
DMT 5.1
chalcone synthase 5.0
arginine decarboxylase 5.0
5alpha-reductase 5.0
5alpha-reductase 5.0
PRA 4.9
citrate synthase 4.9
ribonucleotide reductase 4.9
ribonucleotide reductase 4.8
arginine decarboxylase 4.7
cysteine synthase 4.7
endonuclease 4.7
cellulose synthase 4.7
GTP cyclohydrolase I 4.7
polynucleotide kinase 4.6
3-hydroxyacyl-CoA dehydrogenase 4.6
mu-calpain 4.6
GCA 4.6
CEP 4.5
creatine kinase 4.5
FAST 4.4
m-calpain 4.3
lignin peroxidase 4.2
ferrochelatase 4.2
Rex 4.2
MPP 4.1
GAS 4.1
SCS 4.0
calcium pump 4.0
RNase III 4.0
CEP 3.9
nitrogenase 3.8
cellulose synthase 3.7
histone acetyltransferase 3.6
LPL 3.6
DAT 3.5
thymidine kinase 3.5
sialyltransferase 3.4
sialyltransferase 3.4
sialyltransferase 3.4
chloramphenicol acetyltransferase 3.3
DNA polymerase 3.3
ornithine transcarbamylase 3.3
succinic dehydrogenase 3.2
thymidylate synthase 3.2
S1 nuclease 3.2
PCP 3.1
phosphofructokinase 3.1
dihydrofolate reductase 3.1
adenylate kinase 3.1
RNA polymerase 3.0
AMPK 3.0
HIV-1 protease 3.0
more...
Compound
BC 75 14.0
5,10-methenyltetrahydrofolate 11.9
Isopimaric acid 10.8
5-Bromouracil 9.8
Glycin 9.8
thietane 9.7
PPBP 9.5
4-iodobenzamide 9.2
oxetane 9.1
2-mercaptosuccinic acid 9.0
pyrimidine 8.5
pyrimidine 8.4
FAD 8.2
Pterin 8.0
FK520 7.7
Acriflavine 7.4
Pregnane 7.4
10-formyltetrahydrofolate 7.3
B 5 7.3
Fluvoxamine 7.2
diethyl malonate 6.9
diethyl malonate 6.9
Phytoene 6.9
Phytoene 6.9
Pseudouridine 6.9
Efron 6.8
Practolol 6.7
TMG 6.7
IBP 6.7
IBP 6.7
Ajmaline 6.7
TMF 6.6
Mibefradil 6.6
CUE 6.5
Esmolol 6.5
PAE 6.4
EAA 6.4
MOD 6.3
pregnane-3,20-dione 6.3
Pentazocine 6.3
PRD 6.2
pregnane-3,20-dione 6.2
Flavin 6.2
Pentazocine 6.1
Ecdysone 6.0
Cyanidin 5.9
Pregnenolone 5.8
DMPP 5.8
Paeoniflorin 5.8
NPR 5.8
Psoralen 5.7
Diacetyl 5.7
Sitosterol 5.6
Meloxicam 5.6
Phalloidin 5.6
Cefazolin 5.6
Kynurenic acid 5.5
Nonylphenol 5.4
HN2 5.4
TES 5.3
Morin 5.3
SPF 5.2
Phenoxybenzamine 5.2
Glyphosate 5.2
MPA 5.2
MPA 5.2
MPA 5.1
Leucovorin 5.1
Crystal Violet 5.1
Factor X 5.1
DMT 5.1
FMN 5.0
undecane 5.0
XPA 5.0
Zirconia 5.0
XPA 5.0
MTC 5.0
Carnosine 5.0
DMS 5.0
Phenylalanine 5.0
more...