Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.99.3 (PRE)
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Human Gene/Protein
photolyase 13.9
WDR87 13.0
Epitheliasin 13.0
epitheliasin 13.0
photolyase-like 13.0
PHR1 11.7
ZK1 11.2
POLR1B 11.2
FBXL21 10.8
FADH2 10.8
Tpr1 10.7
FBXL3 10.6
CRY 10.3
G-protein coupled receptor protein 10.2
cryptochrome 1 10.2
CRY1 10.1
Helicase-like transcription factor 10.0
SPF30 10.0
HPH2 10.0
PIK3C2B 10.0
cryptochrome 2 9.8
XPE 9.7
high mobility group 1 protein 9.7
calcium binding and coiled-coil domain 2 9.7
Sp3 transcription factor 9.6
A. nidulans) 9.6
CRY2 9.5
REDD2 9.4
Micrococcus luteus UV endonuclease 9.4
CPD 9.4
DLAD 9.4
adenylosuccinate synthase 9.4
PKE 9.4
hPR 9.3
damage-specific DNA binding protein 1 9.3
ALT2 9.2
REC1 9.2
GDE1 9.2
DNA repair enzyme 9.1
CHOD 9.1
more...
Disease
CHRS 10.6
COND 10.3
BOE 10.1
XPE 9.6
Fowlpox 9.3
pediatric liver cancer 8.6
EBSS 8.5
Polymorphic light eruption 8.4
XP-A 8.2
Shope fibroma 7.8
xeroderma pigmentosum 7.4
trichothiodystrophy 7.1
AN2 6.6
hypo-osmolality 6.5
Choroid 6.4
Choroid 6.4
XPD 6.3
CSB 6.0
HBD 6.0
CSB 5.9
complete paraplegia 5.9
PIE 5.9
rind 5.8
BPP 5.8
RP18 5.8
autoimmune lymphoproliferative syndrome 5.8
NPHP1 5.8
BED 5.8
trance 5.7
keratosis 5.7
XPB 5.6
HIV encephalitis 5.6
Lowe syndrome 5.5
DIN 5.5
DIN 5.5
SCA1 5.4
PER 5.4
Bronchiolitis obliterans 5.4
ABS 5.2
CHR 5.2
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Symptom
Psychiatric symptoms 5.7
Halo 5.2
skin damage 5.0
exhaustion 4.4
muscle stiffness 3.8
fatigue 3.7
Neuropathic pain 3.5
bloating 3.3
hunger 3.1
tense 2.9
erythema 2.9
pallor 2.7
overweight 2.5
constipation 2.3
acute pain 2.1
analgesia 2.0
discomfort 1.9
wheezing 1.8
discomfort 1.8
low back pain 1.7
numbness 1.7
hyperoxia 1.7
cachexia 1.6
hypotonia 1.5
sleepiness 1.4
myalgia 1.3
nausea 1.1
anesthesia 1.0
collapse 0.8
nausea and vomiting 0.8
pain 0.6
agitation 0.5
weakness 0.4
stigma 0.3
seizures 0.0
tremor -0.2
diarrhea -0.2
starvation -0.6
dyspnea -0.8
headache -0.8
more...
Drug
Posilac 8.7
FAD 8.2
Trilostane 7.2
Lutalyse 7.1
FSH-beta 7.0
FSH-beta 7.0
FSH-beta 6.7
Escitalopram 6.1
GNA 5.9
Pregnenolone 5.8
Flavin 5.6
CTT 5.3
Finasteride 5.2
Gabapentin 5.2
MTC 5.0
Sinemet 4.9
Orphan 4.9
Donepezil 4.9
TES 4.9
GHRP 4.9
NBT 4.6
Camp 4.5
OTC 4.5
PMEA 4.5
Bupivacaine 4.4
DEX 4.2
Sodium nitroprusside 4.1
-deoxyadenosine 4.0
OTC 4.0
DMI 4.0
Fragment 3.8
DNase I 3.8
Horizon 3.8
Fentanyl 3.7
IL-1ra 3.6
Prednisolone 3.5
Growth hormone 3.5
Growth hormone 3.4
balanced salt solution 3.4
MAP 3.4
more...
Enzyme
PRE 14.0
N-methylglutamate synthase 13.0
HY2 8.8
deoxyribonuclease 8.0
endonuclease V 7.8
DNA ligase 7.8
DNA ligase 7.8
chorismate synthase 7.6
AP lyase 7.1
hydroxynitrile lyase 7.0
hydroxynitrile lyase 7.0
endodeoxyribonuclease 6.9
hydroxynitrile lyase 6.8
protochlorophyllide oxidoreductase 6.7
adenylosuccinate synthetase 6.3
venom phosphodiesterase 6.2
cytochrome c peroxidase 6.2
tannase 5.9
LIS 5.8
phospholipid hydroperoxide glutathione peroxidase 5.6
branched-chain alpha-keto acid dehydrogenase 5.4
3'-exonuclease 5.4
PST 5.3
DNase II 5.3
Protein 2 5.3
tyrosine aminotransferase 5.2
CGT 5.2
DMT 5.1
chalcone synthase 5.0
arginine decarboxylase 5.0
5alpha-reductase 5.0
5alpha-reductase 5.0
PRA 4.9
citrate synthase 4.9
ribonucleotide reductase 4.9
ribonucleotide reductase 4.8
arginine decarboxylase 4.7
cysteine synthase 4.7
endonuclease 4.7
cellulose synthase 4.7
more...
Compound
BC 75 14.0
5,10-methenyltetrahydrofolate 11.9
Isopimaric acid 10.8
Glycin 9.8
5-Bromouracil 9.8
thietane 9.7
PPBP 9.5
4-iodobenzamide 9.2
oxetane 9.1
2-mercaptosuccinic acid 9.0
pyrimidine 8.5
pyrimidine 8.4
FAD 8.2
Pterin 8.0
FK520 7.7
Acriflavine 7.4
Pregnane 7.4
10-formyltetrahydrofolate 7.3
B 5 7.3
Fluvoxamine 7.2
diethyl malonate 6.9
diethyl malonate 6.9
Phytoene 6.9
Phytoene 6.9
Pseudouridine 6.9
Efron 6.8
Practolol 6.7
TMG 6.7
IBP 6.7
IBP 6.7
Ajmaline 6.7
TMF 6.6
Mibefradil 6.6
CUE 6.5
Esmolol 6.5
PAE 6.4
EAA 6.4
MOD 6.3
pregnane-3,20-dione 6.3
Pentazocine 6.3
more...