Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.99.3 (
PRE
)
1,923
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
photolyase
675
Sep
132
Mol
124
FAD
95
CPD
40
DNA repair enzyme
35
NMR
31
PHR1
29
endonuclease
29
progesterone receptor
26
creatine kinase
25
CRY1
25
FADH2
24
flavoprotein
23
Chlamydomonas
22
insulin
22
ATP
21
cytokine
20
IL-6
20
Gen
20
TRE
18
CRY
18
polypeptide
18
ANOVA
18
sigma receptor
18
TNF
16
IL-10
15
photolyase-like
15
CRY2
14
CLOCK
14
fused
13
histone
12
hemoglobin
11
BMAL1
11
glucocorticoid receptor
11
endoplasmic reticulum
10
superoxide dismutase
10
p53
10
leptin
10
IL-4
10
hole
9
alkaline phosphatase
9
DNA polymerase
9
EPR
9
tumor necrosis factor
9
ubiquitin
9
cryptochrome 1
8
interleukin-6
8
lactate dehydrogenase
8
RNA polymerase II
8
citrate synthase
8
tRNA
8
Sp1
7
gut
7
MAPK
7
growth hormone
7
PCC
7
cryptochrome 2
7
lipopolysaccharide
7
DNase I
7
DNA-binding domain
7
cytochrome c
6
FMN
6
NMDA receptor
6
myoglobin
6
collagen
6
RNA polymerase I
6
unknown function
6
transcriptional repressor
6
estrogen receptor
6
caspase-3
6
A. nidulans
6
trithorax
6
MF1
6
basic helix-loop-helix
6
CO2
6
adiponectin
6
apoE
6
NADH
5
D. melanogaster
5
nuclear protein
5
follicle-stimulating hormone
5
lamp
5
perilipin
5
ATPase
5
androgen receptor
5
erythroid
5
GSH
5
thymidine kinase
5
tumor necrosis factor alpha
5
RPE
5
glutathione peroxidase
5
IL-2
5
myosin heavy chain
5
brain-derived neurotrophic factor
5
ribonucleotide reductase
5
ABC
5
casein
5
DNA repair protein
5
vascular endothelial growth factor
4
telomeric
4
cyclin D1
4
CD8
4
Pol
4
phosphatase
4
CD105
4
IgA
4
JNK
4
opioid receptor
4
RACE
4
DNA binding protein
4
muscle protein
4
amyloid precursor protein
4
amylase
4
thymus
4
Creatine kinase
4
interferon-gamma
4
C-reactive protein
4
renin
4
Pseudomonas
4
histone H3
4
lysozyme
4
SPF
4
aspartate aminotransferase
4
EXP
4
HLA
4
PRL
4
proto-oncogene
4
COP1
4
mTOR
4
HDL
4
epsilon-globin
4
MLR
4
mer
4
catalase
4
TNF-alpha
4
pheromone receptor
4
prolactin
4
REC
4
p38
4
hormone receptor
4
beta-glucuronidase
3
insulin-like growth factor
3
chemokine
3
FBXL3
3
glucagon
3
ERK1
3
FSH
3
beta-endorphin
3
SBP
3
fibronectin
3
NF-IL6
3
LHRH
3
HIS3
3
pol
3
ERK
3
CYC1
3
CAT
3
mitogen-activated protein
3
p21
3
more...
Disease
cancer
46
tumor
39
xeroderma pigmentosum
30
skin cancer
20
cold
20
depression
17
obesity
14
melanoma
13
carcinogenesis
12
Alzheimer's disease
11
breast cancer
11
stroke
11
Parkinson's disease
8
type 2 diabetes
8
amnesia
7
PCC
7
diabetes
7
cholera
7
pheochromocytoma
7
keratosis
7
ischemia
6
Haemophilus
6
hepatocellular carcinoma
6
HIV
6
hypertension
6
SEM
6
plaque
6
carcinoma
5
MCF
5
confusion
5
infectious diseases
5
GSH
5
tumorigenesis
5
AIDS
4
epilepsy
4
fits
4
photosensitivity
4
hepatitis B
4
cognitive impairment
4
XPD
4
dementia
4
cirrhosis
4
NAME
4
amyotrophic lateral sclerosis
4
psychological stress
4
hepatoblastoma
4
delirium
4
colon cancer
4
trichothiodystrophy
3
coma
3
ATM
3
metastases
3
memory impairment
3
liver cancer
3
myocardial ischemia
3
XP-A
3
liver cancer
3
preeclampsia
3
virus infection
3
bronchopulmonary dysplasia
3
rind
3
Fowlpox
3
hyperglycemia
3
squamous cell carcinoma
3
PER
3
ovarian cancer
3
XPE
3
cytomegalovirus
3
cardiovascular disease
3
HDL3
2
paraplegia
2
chronic obstructive pulmonary disease
2
Shope fibroma
2
Frey
2
substance abuse
2
herpes simplex
2
DIN
2
SCID
2
carcinoma in situ
2
mole
2
prostate cancer
2
avian leukosis
2
Brown
2
Choroid
2
lung cancer
2
tetanus
2
Cockayne syndrome
2
CTX
2
DIN
2
tumor progression
2
CSB
2
neuroblastoma
2
dengue
2
myopathy
2
sarcoma
2
parkinsonism
2
schizophrenia
2
substance use
2
Anterior
2
ICC
2
myocardial infarction
2
addiction
2
lymphedema
2
mental retardation
2
cornea
2
proteinuria
2
PPP
2
Choroid
2
HDL2
2
ICT
2
ICC
2
heart disease
2
PIN
2
SARS
2
mental retardation
2
CSB
2
drug addiction
2
neoplastic transformation
2
SDS
2
adenocarcinoma
2
mammary tumor
2
adenoma
2
glioma
2
Hodgkin's disease
2
bone disease
2
ABS
2
vaccinia
2
PCP
2
influenza
2
glaucoma
2
tumor growth
2
uterus
2
pneumonia
2
INS
2
malaria
2
ABS
2
Infection
2
Evans
2
basal cell carcinoma
2
osteoarthritis
1
hypothyroidism
1
Polymorphic light eruption
1
borderline personality disorder
1
malnutrition
1
bends
1
type 1 diabetes
1
neuroticism
1
sepsis
1
HRS
1
neutropenia
1
Lowe syndrome
1
gastric cancer
1
dehydration
1
glucose intolerance
1
CEP
1
Rett syndrome
1
herniated disc
1
systemic lupus erythematosus
1
immunodeficiency
1
Pituitary
1
more...
Symptom
fatigue
41
pain
24
exhaustion
17
anesthesia
13
overweight
9
analgesia
7
erythema
6
discomfort
5
discomfort
5
seizures
5
diarrhea
3
nausea
3
skin damage
3
weakness
3
hunger
3
constipation
3
collapse
3
sleepiness
2
low back pain
2
headache
2
pallor
1
acute pain
1
cachexia
1
myalgia
1
numbness
1
stigma
1
bloating
1
tremor
1
tense
1
wheezing
1
nausea and vomiting
1
agitation
1
muscle stiffness
1
hyperoxia
1
starvation
1
dyspnea
1
hypotonia
1
Psychiatric symptoms
1
Neuropathic pain
1
Halo
1
Drug
FAD
95
Dermatol
19
MAP
10
caffeine
8
DNase I
7
lysine
6
ABC
5
NADH
5
IL-2
5
IFN-gamma
3
Posture
3
lactose
3
Bifidobacterium
3
CTX
2
Gel
2
-deoxyadenosine
2
vitamin E
2
DMI
2
Mutagen
2
Growth hormone
2
Fragment
2
CTX
2
EE2
2
Gabapentin
2
Nephron
2
CTX
2
Asn
2
ADM
2
Dial
2
Growth hormone
2
NBT
2
PCP
2
ROS
2
THF
2
CAM
2
Leaf
2
Bupivacaine
1
balanced salt solution
1
Donepezil
1
CSF
1
Parkin
1
PTC
1
Posilac
1
Glycerol
1
citric acid
1
Lutalyse
1
IL-1ra
1
Albumin
1
Flavin
1
Parkin
1
Sinemet
1
MTC
1
AZT
1
OTC
1
TES
1
GNA
1
Cardiovasc
1
FSH-beta
1
Escitalopram
1
Camp
1
Pregnenolone
1
Biopolymers
1
Kenyan
1
FSH-beta
1
CTT
1
Triclosan
1
Orphan
1
Sodium nitroprusside
1
Horizon
1
OTC
1
Finasteride
1
PMEA
1
AZT
1
FSH-beta
1
Prednisolone
1
ROC
1
GHRP
1
DEX
1
Trilostane
1
Vitamin E
1
Fentanyl
1
CDP
1
Monit
1
ALA
1
Enzyme
PRE
1923
DNA ligase
36
DNA ligase
36
endonuclease
29
creatine kinase
25
deoxyribonuclease
22
RNA polymerase
17
mitogen-activated protein kinase
15
luciferase
12
DNA polymerase
10
focal adhesion kinase
10
superoxide dismutase
10
alkaline phosphatase
9
lactate dehydrogenase
8
citrate synthase
8
ERK
7
catalase
7
aspartate aminotransferase
6
thymidine kinase
5
AMP-activated protein kinase
5
caspase-3
5
glutathione peroxidase
5
ATPase
5
beta-galactosidase
5
ribonucleotide reductase
5
ribonucleotide reductase
5
complex I
4
protein kinase C
4
lysozyme
4
renin
4
cytochrome c peroxidase
3
glucose-6-phosphate dehydrogenase
3
peroxidase
3
ACS
3
AMPK
3
alanine aminotransferase
3
dihydrofolate reductase
3
AMPK
3
PRA
3
chalcone synthase
3
calcineurin
3
MEK
3
lipase
3
proteasome
3
beta-glucuronidase
3
nitrogenase
3
chloramphenicol acetyltransferase
3
tyrosine aminotransferase
3
acetylcholinesterase
2
caspase-8
2
MAP
2
cdc2
2
PCP
2
succinate dehydrogenase
2
histone acetyltransferase
2
NADPH oxidase
2
PST
2
GSK
2
ATP synthase
2
DNase
2
endonuclease V
2
5alpha-reductase
2
AST
2
xanthine oxidase
2
AP lyase
2
5alpha-reductase
2
protein kinase
2
S1 nuclease
2
protochlorophyllide oxidoreductase
2
hexokinase
2
NADPH oxidase
2
MPP
2
topoisomerase
2
topoisomerase
2
phosphofructokinase
2
venom phosphodiesterase
2
glutathione S-transferase
2
PARP
2
caspase-1
2
thymidylate synthase
2
phospholipid hydroperoxide glutathione peroxidase
1
lignin peroxidase
1
hydroxynitrile lyase
1
hypoxanthine-guanine phosphoribosyltransferase
1
GTP cyclohydrolase I
1
adenosine deaminase
1
sialyltransferase
1
mu-calpain
1
NADH dehydrogenase
1
branched-chain alpha-keto acid dehydrogenase
1
hydrogenase
1
hydrogenase
1
sialyltransferase
1
adenylosuccinate synthetase
1
polynucleotide kinase
1
ornithine transcarbamylase
1
DMT
1
adenosine deaminase
1
CEP
1
reverse transcriptase
1
Protein 2
1
m-calpain
1
hydroxynitrile lyase
1
3'-exonuclease
1
N-methylglutamate synthase
1
trypsin
1
aldehyde dehydrogenase
1
endodeoxyribonuclease
1
chymotrypsin
1
FAST
1
glyceraldehyde-3-phosphate dehydrogenase
1
glyceraldehyde-3-phosphate dehydrogenase
1
HY2
1
ferrochelatase
1
succinic dehydrogenase
1
3-hydroxyacyl-CoA dehydrogenase
1
chorismate synthase
1
calcium pump
1
thrombin
1
glucose oxidase
1
cytochrome oxidase
1
glyceraldehyde-3-phosphate dehydrogenase
1
thromboplastin
1
DAT
1
tannase
1
cysteine synthase
1
acid phosphatase
1
proteinase K
1
SCS
1
GCA
1
malate dehydrogenase
1
GAS
1
urokinase-type plasminogen activator
1
micrococcal nuclease
1
caspase-9
1
NO synthase
1
sialyltransferase
1
HIV-1 protease
1
IKK
1
lipoprotein lipase
1
cellulose synthase
1
DNase II
1
phospholipase C
1
SPC
1
cathepsin B
1
gamma-glutamyl transpeptidase
1
hydroxynitrile lyase
1
adenylate kinase
1
PKG
1
MMP
1
Rex
1
adenylate cyclase
1
RNase III
1
CEP
1
arginine decarboxylase
1
tyrosinase
1
LPL
1
cellulose synthase
1
collagenase
1
LIS
1
more...
Compound
DNA
694
pyrimidine
426
pyrimidine
426
Dec
141
FAD
97
oxygen
82
water
72
tryptophan
61
tryptophan
60
tryptophan
60
tryptophan
60
5,10-methenyltetrahydrofolate
42
hydrogen
36
Clin
33
glucose
31
His
24
phosphate
24
arginine
23
nitrogen
23
tyrosine
21
ATP
21
sodium
20
Phe
17
TNF
16
alanine
14
sulfate
14
calcium
13
oxetane
13
lysine
12
cysteine
10
zinc
10
CO2
10
Progesterone
10
salt
10
Asp
10
phosphorus
9
creatinine
9
serine
9
iron
9
Cortisol
9
proline
9
leucine
9
isopropanol
8
acetate
8
caffeine
8
galactose
7
nitric oxide
7
potassium
7
ethanol
7
glutamate
7
NH2
6
copper
6
piperidine
6
Cardiol
6
piperidine
6
manganese
6
FMN
6
glutamine
6
acetonitrile
5
NADH
5
GSH
5
threonine
5
ammonium
5
GSH
5
Adrenal
5
MAP
5
cAMP
5
glycerol
5
valine
5
urea
5
Gly
4
PAS
4
methyl methanesulfonate
4
iodine
4
MOD
4
SPF
4
hydroquinone
4
5-HT
4
noradrenaline
4
mercury
4
Insulin
4
NMDA
4
A 3
4
aspartic acid
4
guanidine
4
acetone
4
aspartic acid
4
aspartic acid
4
methanol
4
methionine
4
glutamic acid
4
aspartic acid
4
aldosterone
3
Adenine
3
DDP
3
CAT
3
CAT
3
DMS
3
MPA
3
silver
3
nitrate
3
NIDA
3
Estrogen
3
MDA
3
ACS
3
ACS
3
Fluvoxamine
3
asparagine
3
Testosterone
3
Lactate
3
PAR
3
PMA
3
chloroform
3
CAT
3
COS
3
MPTP
3
PEG
3
Testosterone
3
Diazepam
3
MPA
3
MPA
3
gallic acid
3
pentose
2
Adenosine
2
ADP
2
MTT
2
phenol
2
ADP
2
NBT
2
pentose
2
nitrous acid
2
8-OHdG
2
FFA
2
PAC
2
DMPP
2
ADP
2
GTP
2
PPBP
2
NAD
2
Ile
2
dipropyl
2
NADPH
2
DAP
2
pentose
2
T10
2
Prednisone
2
pentose
2
Flavin
2
Glyphosate
2
Phenylalanine
2
GSSG
2
silicon
2
thietane
2
Thiamine
2
ICI
2
PGE2
2
Optimal
2
DPH
2
ACh
2
Estrogen
2
more...