Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.99.3 (PRE)
1,923 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
photolyase 675
Sep 132
Mol 124
FAD 95
CPD 40
DNA repair enzyme 35
NMR 31
PHR1 29
endonuclease 29
progesterone receptor 26
creatine kinase 25
CRY1 25
FADH2 24
flavoprotein 23
Chlamydomonas 22
insulin 22
ATP 21
cytokine 20
IL-6 20
Gen 20
TRE 18
CRY 18
polypeptide 18
ANOVA 18
sigma receptor 18
TNF 16
IL-10 15
photolyase-like 15
CRY2 14
CLOCK 14
fused 13
histone 12
hemoglobin 11
BMAL1 11
glucocorticoid receptor 11
endoplasmic reticulum 10
superoxide dismutase 10
p53 10
leptin 10
IL-4 10
hole 9
alkaline phosphatase 9
DNA polymerase 9
EPR 9
tumor necrosis factor 9
ubiquitin 9
cryptochrome 1 8
interleukin-6 8
lactate dehydrogenase 8
RNA polymerase II 8
citrate synthase 8
tRNA 8
Sp1 7
gut 7
MAPK 7
growth hormone 7
PCC 7
cryptochrome 2 7
lipopolysaccharide 7
DNase I 7
DNA-binding domain 7
cytochrome c 6
FMN 6
NMDA receptor 6
myoglobin 6
collagen 6
RNA polymerase I 6
unknown function 6
transcriptional repressor 6
estrogen receptor 6
caspase-3 6
A. nidulans 6
trithorax 6
MF1 6
basic helix-loop-helix 6
CO2 6
adiponectin 6
apoE 6
NADH 5
D. melanogaster 5
nuclear protein 5
follicle-stimulating hormone 5
lamp 5
perilipin 5
ATPase 5
androgen receptor 5
erythroid 5
GSH 5
thymidine kinase 5
tumor necrosis factor alpha 5
RPE 5
glutathione peroxidase 5
IL-2 5
myosin heavy chain 5
brain-derived neurotrophic factor 5
ribonucleotide reductase 5
ABC 5
casein 5
DNA repair protein 5
vascular endothelial growth factor 4
telomeric 4
cyclin D1 4
CD8 4
Pol 4
phosphatase 4
CD105 4
IgA 4
JNK 4
opioid receptor 4
RACE 4
DNA binding protein 4
muscle protein 4
amyloid precursor protein 4
amylase 4
thymus 4
Creatine kinase 4
interferon-gamma 4
C-reactive protein 4
renin 4
Pseudomonas 4
histone H3 4
lysozyme 4
SPF 4
aspartate aminotransferase 4
EXP 4
HLA 4
PRL 4
proto-oncogene 4
COP1 4
mTOR 4
HDL 4
epsilon-globin 4
MLR 4
mer 4
catalase 4
TNF-alpha 4
pheromone receptor 4
prolactin 4
REC 4
p38 4
hormone receptor 4
beta-glucuronidase 3
insulin-like growth factor 3
chemokine 3
FBXL3 3
glucagon 3
ERK1 3
FSH 3
beta-endorphin 3
SBP 3
fibronectin 3
NF-IL6 3
LHRH 3
HIS3 3
pol 3
ERK 3
CYC1 3
CAT 3
mitogen-activated protein 3
p21 3
more...
Disease
cancer 46
tumor 39
xeroderma pigmentosum 30
skin cancer 20
cold 20
depression 17
obesity 14
melanoma 13
carcinogenesis 12
Alzheimer's disease 11
breast cancer 11
stroke 11
Parkinson's disease 8
type 2 diabetes 8
amnesia 7
PCC 7
diabetes 7
cholera 7
pheochromocytoma 7
keratosis 7
ischemia 6
Haemophilus 6
hepatocellular carcinoma 6
HIV 6
hypertension 6
SEM 6
plaque 6
carcinoma 5
MCF 5
confusion 5
infectious diseases 5
GSH 5
tumorigenesis 5
AIDS 4
epilepsy 4
fits 4
photosensitivity 4
hepatitis B 4
cognitive impairment 4
XPD 4
dementia 4
cirrhosis 4
NAME 4
amyotrophic lateral sclerosis 4
psychological stress 4
hepatoblastoma 4
delirium 4
colon cancer 4
trichothiodystrophy 3
coma 3
ATM 3
metastases 3
memory impairment 3
liver cancer 3
myocardial ischemia 3
XP-A 3
liver cancer 3
preeclampsia 3
virus infection 3
bronchopulmonary dysplasia 3
rind 3
Fowlpox 3
hyperglycemia 3
squamous cell carcinoma 3
PER 3
ovarian cancer 3
XPE 3
cytomegalovirus 3
cardiovascular disease 3
HDL3 2
paraplegia 2
chronic obstructive pulmonary disease 2
Shope fibroma 2
Frey 2
substance abuse 2
herpes simplex 2
DIN 2
SCID 2
carcinoma in situ 2
mole 2
prostate cancer 2
avian leukosis 2
Brown 2
Choroid 2
lung cancer 2
tetanus 2
Cockayne syndrome 2
CTX 2
DIN 2
tumor progression 2
CSB 2
neuroblastoma 2
dengue 2
myopathy 2
sarcoma 2
parkinsonism 2
schizophrenia 2
substance use 2
Anterior 2
ICC 2
myocardial infarction 2
addiction 2
lymphedema 2
mental retardation 2
cornea 2
proteinuria 2
PPP 2
Choroid 2
HDL2 2
ICT 2
ICC 2
heart disease 2
PIN 2
SARS 2
mental retardation 2
CSB 2
drug addiction 2
neoplastic transformation 2
SDS 2
adenocarcinoma 2
mammary tumor 2
adenoma 2
glioma 2
Hodgkin's disease 2
bone disease 2
ABS 2
vaccinia 2
PCP 2
influenza 2
glaucoma 2
tumor growth 2
uterus 2
pneumonia 2
INS 2
malaria 2
ABS 2
Infection 2
Evans 2
basal cell carcinoma 2
osteoarthritis 1
hypothyroidism 1
Polymorphic light eruption 1
borderline personality disorder 1
malnutrition 1
bends 1
type 1 diabetes 1
neuroticism 1
sepsis 1
HRS 1
neutropenia 1
Lowe syndrome 1
gastric cancer 1
dehydration 1
glucose intolerance 1
CEP 1
Rett syndrome 1
herniated disc 1
systemic lupus erythematosus 1
immunodeficiency 1
Pituitary 1
more...
Symptom
fatigue 41
pain 24
exhaustion 17
anesthesia 13
overweight 9
analgesia 7
erythema 6
discomfort 5
discomfort 5
seizures 5
diarrhea 3
nausea 3
skin damage 3
weakness 3
hunger 3
constipation 3
collapse 3
sleepiness 2
low back pain 2
headache 2
pallor 1
acute pain 1
cachexia 1
myalgia 1
numbness 1
stigma 1
bloating 1
tremor 1
tense 1
wheezing 1
nausea and vomiting 1
agitation 1
muscle stiffness 1
hyperoxia 1
starvation 1
dyspnea 1
hypotonia 1
Psychiatric symptoms 1
Neuropathic pain 1
Halo 1
Drug
FAD 95
Dermatol 19
MAP 10
caffeine 8
DNase I 7
lysine 6
ABC 5
NADH 5
IL-2 5
IFN-gamma 3
Posture 3
lactose 3
Bifidobacterium 3
CTX 2
Gel 2
-deoxyadenosine 2
vitamin E 2
DMI 2
Mutagen 2
Growth hormone 2
Fragment 2
CTX 2
EE2 2
Gabapentin 2
Nephron 2
CTX 2
Asn 2
ADM 2
Dial 2
Growth hormone 2
NBT 2
PCP 2
ROS 2
THF 2
CAM 2
Leaf 2
Bupivacaine 1
balanced salt solution 1
Donepezil 1
CSF 1
Parkin 1
PTC 1
Posilac 1
Glycerol 1
citric acid 1
Lutalyse 1
IL-1ra 1
Albumin 1
Flavin 1
Parkin 1
Sinemet 1
MTC 1
AZT 1
OTC 1
TES 1
GNA 1
Cardiovasc 1
FSH-beta 1
Escitalopram 1
Camp 1
Pregnenolone 1
Biopolymers 1
Kenyan 1
FSH-beta 1
CTT 1
Triclosan 1
Orphan 1
Sodium nitroprusside 1
Horizon 1
OTC 1
Finasteride 1
PMEA 1
AZT 1
FSH-beta 1
Prednisolone 1
ROC 1
GHRP 1
DEX 1
Trilostane 1
Vitamin E 1
Fentanyl 1
CDP 1
Monit 1
ALA 1
Enzyme
PRE 1923
DNA ligase 36
DNA ligase 36
endonuclease 29
creatine kinase 25
deoxyribonuclease 22
RNA polymerase 17
mitogen-activated protein kinase 15
luciferase 12
DNA polymerase 10
focal adhesion kinase 10
superoxide dismutase 10
alkaline phosphatase 9
lactate dehydrogenase 8
citrate synthase 8
ERK 7
catalase 7
aspartate aminotransferase 6
thymidine kinase 5
AMP-activated protein kinase 5
caspase-3 5
glutathione peroxidase 5
ATPase 5
beta-galactosidase 5
ribonucleotide reductase 5
ribonucleotide reductase 5
complex I 4
protein kinase C 4
lysozyme 4
renin 4
cytochrome c peroxidase 3
glucose-6-phosphate dehydrogenase 3
peroxidase 3
ACS 3
AMPK 3
alanine aminotransferase 3
dihydrofolate reductase 3
AMPK 3
PRA 3
chalcone synthase 3
calcineurin 3
MEK 3
lipase 3
proteasome 3
beta-glucuronidase 3
nitrogenase 3
chloramphenicol acetyltransferase 3
tyrosine aminotransferase 3
acetylcholinesterase 2
caspase-8 2
MAP 2
cdc2 2
PCP 2
succinate dehydrogenase 2
histone acetyltransferase 2
NADPH oxidase 2
PST 2
GSK 2
ATP synthase 2
DNase 2
endonuclease V 2
5alpha-reductase 2
AST 2
xanthine oxidase 2
AP lyase 2
5alpha-reductase 2
protein kinase 2
S1 nuclease 2
protochlorophyllide oxidoreductase 2
hexokinase 2
NADPH oxidase 2
MPP 2
topoisomerase 2
topoisomerase 2
phosphofructokinase 2
venom phosphodiesterase 2
glutathione S-transferase 2
PARP 2
caspase-1 2
thymidylate synthase 2
phospholipid hydroperoxide glutathione peroxidase 1
lignin peroxidase 1
hydroxynitrile lyase 1
hypoxanthine-guanine phosphoribosyltransferase 1
GTP cyclohydrolase I 1
adenosine deaminase 1
sialyltransferase 1
mu-calpain 1
NADH dehydrogenase 1
branched-chain alpha-keto acid dehydrogenase 1
hydrogenase 1
hydrogenase 1
sialyltransferase 1
adenylosuccinate synthetase 1
polynucleotide kinase 1
ornithine transcarbamylase 1
DMT 1
adenosine deaminase 1
CEP 1
reverse transcriptase 1
Protein 2 1
m-calpain 1
hydroxynitrile lyase 1
3'-exonuclease 1
N-methylglutamate synthase 1
trypsin 1
aldehyde dehydrogenase 1
endodeoxyribonuclease 1
chymotrypsin 1
FAST 1
glyceraldehyde-3-phosphate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
HY2 1
ferrochelatase 1
succinic dehydrogenase 1
3-hydroxyacyl-CoA dehydrogenase 1
chorismate synthase 1
calcium pump 1
thrombin 1
glucose oxidase 1
cytochrome oxidase 1
glyceraldehyde-3-phosphate dehydrogenase 1
thromboplastin 1
DAT 1
tannase 1
cysteine synthase 1
acid phosphatase 1
proteinase K 1
SCS 1
GCA 1
malate dehydrogenase 1
GAS 1
urokinase-type plasminogen activator 1
micrococcal nuclease 1
caspase-9 1
NO synthase 1
sialyltransferase 1
HIV-1 protease 1
IKK 1
lipoprotein lipase 1
cellulose synthase 1
DNase II 1
phospholipase C 1
SPC 1
cathepsin B 1
gamma-glutamyl transpeptidase 1
hydroxynitrile lyase 1
adenylate kinase 1
PKG 1
MMP 1
Rex 1
adenylate cyclase 1
RNase III 1
CEP 1
arginine decarboxylase 1
tyrosinase 1
LPL 1
cellulose synthase 1
collagenase 1
LIS 1
more...
Compound
DNA 694
pyrimidine 426
pyrimidine 426
Dec 141
FAD 97
oxygen 82
water 72
tryptophan 61
tryptophan 60
tryptophan 60
tryptophan 60
5,10-methenyltetrahydrofolate 42
hydrogen 36
Clin 33
glucose 31
His 24
phosphate 24
arginine 23
nitrogen 23
tyrosine 21
ATP 21
sodium 20
Phe 17
TNF 16
alanine 14
sulfate 14
calcium 13
oxetane 13
lysine 12
cysteine 10
zinc 10
CO2 10
Progesterone 10
salt 10
Asp 10
phosphorus 9
creatinine 9
serine 9
iron 9
Cortisol 9
proline 9
leucine 9
isopropanol 8
acetate 8
caffeine 8
galactose 7
nitric oxide 7
potassium 7
ethanol 7
glutamate 7
NH2 6
copper 6
piperidine 6
Cardiol 6
piperidine 6
manganese 6
FMN 6
glutamine 6
acetonitrile 5
NADH 5
GSH 5
threonine 5
ammonium 5
GSH 5
Adrenal 5
MAP 5
cAMP 5
glycerol 5
valine 5
urea 5
Gly 4
PAS 4
methyl methanesulfonate 4
iodine 4
MOD 4
SPF 4
hydroquinone 4
5-HT 4
noradrenaline 4
mercury 4
Insulin 4
NMDA 4
A 3 4
aspartic acid 4
guanidine 4
acetone 4
aspartic acid 4
aspartic acid 4
methanol 4
methionine 4
glutamic acid 4
aspartic acid 4
aldosterone 3
Adenine 3
DDP 3
CAT 3
CAT 3
DMS 3
MPA 3
silver 3
nitrate 3
NIDA 3
Estrogen 3
MDA 3
ACS 3
ACS 3
Fluvoxamine 3
asparagine 3
Testosterone 3
Lactate 3
PAR 3
PMA 3
chloroform 3
CAT 3
COS 3
MPTP 3
PEG 3
Testosterone 3
Diazepam 3
MPA 3
MPA 3
gallic acid 3
pentose 2
Adenosine 2
ADP 2
MTT 2
phenol 2
ADP 2
NBT 2
pentose 2
nitrous acid 2
8-OHdG 2
FFA 2
PAC 2
DMPP 2
ADP 2
GTP 2
PPBP 2
NAD 2
Ile 2
dipropyl 2
NADPH 2
DAP 2
pentose 2
T10 2
Prednisone 2
pentose 2
Flavin 2
Glyphosate 2
Phenylalanine 2
GSSG 2
silicon 2
thietane 2
Thiamine 2
ICI 2
PGE2 2
Optimal 2
DPH 2
ACh 2
Estrogen 2
more...