Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:4.1.99.3 (PRE)
 1,923 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aims of this study were to compare the training load intended by a coach with the training load perceived by the players, over a 45-week professional futsal team season and to compare the variation of session rating of perceived exertion (sRPE) across different periods of the season. Eighteen Brazilian professional futsal players participated in the study. The players' rating of perceived exertion (RPE) and coach's rating of intended exertion (RIE) were collected daily throughout the study. To compare the sRPE variation, the season was divided into 4 periods as follows: preseason (PRE-SEASON), first competitive period (COMP1), intercompetition period (INTER-COMP), and second competitive period (COMP2). Based on the cluster analyses, the training sessions were classified into 3 different intensity zones (low, moderate, and high). In all the season periods and intensity zones, the players' RPEs were lower than the coach's RIE. In the low-intensity zone, the INTER-COMP demonstrated higher sRPE values than did the other periods. In the moderate-intensity zones, the INTER-COMP and COMP2 were similar. Finally, for the high-zone intensity, the PRE-SEASON demonstrated higher values than did the other periods. We concluded that the coach overestimated the training load reported by the players in almost all intensity training zones and season periods. The RPE scale does not seem to be a suitable tool when used by the coach for intended training load. Therefore, technical staff should constantly review the training goals in each season period through daily training load control, always taking into consideration the possibilities and limitations of the RPE method.
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PMID:Monitoring the Intended and Perceived Training Load of a Professional Futsal Team Over 45 Weeks: A Case Study. 2620 Jan 97

Lack of physical exercise is considered an important risk factor for chronic diseases. On the contrary, physical exercise reduces the morbidity rates of obesity, diabetes, bone disease, and hypertension. In order to gain novel molecular and cellular clues, we analyzed the effects of physical exercise on differentiation of mesenchymal circulating progenitor cells (M-CPCs) obtained from runners. We also investigated autophagy and telomerase-related gene expression to evaluate the involvement of specific cellular functions in the differentiation process. We performed cellular and molecular analyses in M-CPCs, obtained by a depletion method, of 22 subjects before (PRE RUN) and after (POST RUN) a half marathon performance. In order to prove our findings, we performed also in vitro analyses by testing the effects of runners' sera on a human bone marrow-derived mesenchymal stem (hBM-MSC) cell line. PCR array analyses of PRE RUN versus POST RUN M-CPC total RNAs put in evidence several genes which appeared to be modulated by physical activity. Our results showed that physical exercise promotes differentiation. Osteogenesis-related genes as RUNX2, MSX1, and SPP1 appeared to be upregulated after the run; data showed also increased levels of BMP2 and BMP6 expressions. SOX9, COL2A1, and COMP gene enhanced expression suggested the induction of chondrocytic differentiation as well. The expression of telomerase-associated genes and of two autophagy-related genes, ATG3 and ULK1, was also affected and correlated positively with MSC differentiation. These data highlight an attractive cellular scenario, outlining the role of autophagic response to physical exercise and suggesting new insights into the benefits of physical exercise in counteracting chronic degenerative conditions.
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PMID:Increased Gene Expression of RUNX2 and SOX9 in Mesenchymal Circulating Progenitors Is Associated with Autophagy during Physical Activity. 3173 74