Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.99.3 (
PRE
)
1,923
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
It was shown that the expression of
HIF-1alpha
in retinal pigment epithelium increased under hypoxic conditions. Eight hours after the start of hypoxic exposure, the expression of
HIF-1alpha
reached the peak and sustained after 24-hour hypoxia. However, the morphology of
PRE
cells began to change and the expression of
HIF-1alpha
decreased after long-term (48-hour) hypoxia. Hypoxia-induced increase in the level of
HIF-1alpha
in RPE. It can be an important step in choriodal neovascularization.
...
PMID:Study of hypoxia-induced expression of HIF-1alpha in retina pigment epithelium. 1822 53
