Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.99.3 (
PRE
)
1,923
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Fibroblasts from patients with xeroderma pigmentosum contain low levels of
photoreactivating enzyme
in comparison to normal cells. Levels vary from 0 (line 1199) to 50 (line 1259) percent of normal. The depressed enzyme levels are not an artifact of low growth rate, age of cell donor, cell culture conditions, assay conditions, the presence of inhibitors, or
mycoplasma
contamination. We show that human fibroblasts can monomerize pyrimidine dimers in vivo.
...
PMID:Xeroderma pigmentosum cells contain low levels of photoreactivating enzyme. 105 87
