Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.2.13 (aldolase)
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Human Gene/Protein
Fructose-bisphosphate aldolase 13.2
C1orf41 13.2
Aldolase 12.2
aldolase A 12.1
DERA 11.5
aldolase B 11.4
phosphofructokinase, platelet 11.2
ATP synthase gamma chain 11.2
2-phospho-D-glycerate hydro-lyase 11.2
Ras suppressor protein 1 10.8
aldolase C 10.8
TALDO 10.6
IL1R3 10.6
aat-1 10.6
glycerate kinase 10.5
N-acetylneuraminate lyase 10.4
CaM-KIIN 10.4
phosphoglyceromutase 10.2
PP25 10.2
np55 10.2
aconitase 2 10.1
sp32 10.0
acyl-CoA synthetase long-chain family member 3 10.0
ALDOB 10.0
ALDOA 9.9
rabconnectin 9.8
hexokinase III 9.8
ribulose-5-phosphate-3-epimerase 9.8
dipeptidyl peptidase 9 9.8
glycogen phosphorylase B 9.8
ALDOC 9.8
transaldolase 9.7
fructokinase 9.7
phosphorylase, glycogen 9.7
sialic acid synthase 9.7
triosephosphate isomerase 9.7
FBA 9.6
TMLHE 9.6
alpha-actinin 2 9.6
KA21 9.6
phosphoglycerate mutase 9.6
phosphoglucose isomerase 9.6
ribose 5-phosphate isomerase 9.5
PFK-A 9.5
APIP 9.5
6-phosphofructokinase 9.4
TP41 9.4
ATP synthase F0 subunit 6 9.4
early B-cell factor 2 9.4
ALDC 9.4
FBPase 9.4
phosphofructokinase 1 9.3
phosphofructokinase 9.3
phosphoglycerate kinase 9.3
bisphosphoglycerate mutase 9.3
Rab GDP dissociation inhibitor beta 9.3
Malic dehydrogenase 9.3
p18 protein 9.2
elongation factor 1-beta 9.2
Alanine-glyoxylate aminotransferase 9.2
ATP synthase subunit alpha 9.2
dihydrodipicolinate synthase 9.1
glycolytic enzyme 9.1
FBP 9.1
glyceraldehyde 3-phosphate dehydrogenase 9.0
Kua 9.0
tubulin beta chain 9.0
D-fructose-1,6-bisphosphate 1-phosphohydrolase 9.0
ANT4 8.9
fructose-bisphosphatase 8.9
talin 1 8.9
aspartyl aminopeptidase 8.9
glyceraldehyde-3-phosphate dehydrogenase 8.9
fructose 1,6-bisphosphatase 8.9
phosphoglucomutase 1 8.9
aconitate hydratase 8.9
aminomethyltransferase 8.8
enolase 8.8
pyruvate kinase 8.8
DLAT 8.8
more...
Disease
Myopathy with tubular aggregates 12.2
Neuromuscular toxicity 11.2
Essential fructosuria 11.2
hereditary fructose intolerance 10.9
Steroid myopathy 10.4
fructose-1,6-diphosphatase deficiency 9.7
floppy baby syndrome 9.5
Fish allergy 9.4
sideroblastosis 9.3
Baker's asthma 9.2
Tuberculoid leprosy 8.3
hereditary nonspherocytic hemolytic anemia 8.2
FIPA 8.2
osteomyelofibrosis 8.0
MGA3 8.0
Necrotic enteritis 7.9
Neonatal hyperbilirubinemia 7.8
JWS 7.8
congenital hemolytic anemia 7.7
Eosinophilic fasciitis 7.6
avitaminosis 7.6
Hers 7.5
congenital hypoplastic anemia 7.5
Angiostrongyliasis 7.4
disorders of carbohydrate metabolism 7.3
Biotin deficiency 7.2
Crescentic glomerulonephritis 7.0
CCV 6.8
Reye 6.7
erythroblastopenia 6.7
Benson 6.7
myofasciitis 6.6
polymyositis 6.5
nagana 6.5
hypoplastic anemia 6.5
alcoholic myopathy 6.5
Klebs 6.4
dermatomyositis 6.4
ALD 6.3
muscle swelling 6.3
FIP 6.2
systemic candidiasis 6.2
Angiostrongylus costaricensis 6.1
Juvenile dermatomyositis 6.1
other autoimmune disease 6.1
primary amebic meningoencephalitis 6.1
vaginosis 5.9
myositis 5.9
Aeromonas hydrophila infection 5.8
oxalosis 5.8
pyruvate kinase deficiency 5.7
FIP 5.7
large cell carcinomas 5.7
LPI 5.7
IGS 5.6
paramyotonia 5.5
HNA 5.5
pellagra 5.5
diabetic cataract 5.4
glycogen storage disease 5.4
CGD 5.4
Alkaptonuria 5.4
idiopathic cardiomyopathy 5.3
enzyme deficiency 5.3
hyperoxaluria 5.3
vitamin B6 deficiency 5.3
MPE 5.3
myopathy 5.3
muscular dystrophy 5.2
fibrocystic disease 5.2
Diaphragm 5.1
GSD I 5.1
placentitis 5.1
Eosinophilia 5.1
LAD2 5.1
polyarthralgia 5.1
scleromyxedema 5.1
progressive muscular atrophy 5.1
perennial rhinitis 4.9
trichinellosis 4.8
more...
Symptom
Intermittent fever 9.5
phosphatemia 6.4
inanition 5.4
muscle cramps 5.3
myalgia 5.2
arm pain 5.2
periorbital edema 5.2
Tenderness 4.6
weakness 4.4
Respiratory symptoms 4.3
Decreased activity 4.1
Anoxia 4.1
ketonuria 4.1
hepatomegaly 4.0
fasciculation 3.8
arthralgia 3.8
tonic-clonic seizure 3.8
thigh pain 3.8
drooling 3.8
CSR 3.7
general problem 3.4
asthenia 3.4
oliguria 3.3
DNA marker 3.3
starvation 3.1
hypoproteinemia 3.0
exertional dyspnea 3.0
erythema 2.9
muscle stiffness 2.9
tachypnea 2.9
sore throat 2.7
skin damage 2.6
shortness of breath 2.4
dysarthria 2.3
hypotonia 2.2
leg pain 2.2
chills 2.1
myoclonus 2.1
tense 2.1
hepatosplenomegaly 2.1
exhaustion 2.0
splenomegaly 1.9
numbness 1.8
paraparesis 1.7
lethargy 1.7
cough 1.6
fatigue 1.5
ophthalmoplegia 1.5
dyspnea 1.4
acute pain 1.2
hemiplegia 1.2
paresthesia 0.9
vomiting 0.8
paresis 0.7
agitation 0.6
diarrhea 0.5
discomfort 0.3
nausea 0.2
hypercapnia 0.2
discomfort 0.2
hypothermia 0.1
tremor -0.0
nausea and vomiting -0.1
low back pain -0.1
abdominal pain -0.2
insomnia -0.2
Ill -0.3
sleepiness -0.5
stigma -0.5
anesthesia -0.6
collapse -0.6
pain -0.7
acidity -0.7
chest pain -0.9
seizures -1.1
angina -1.2
analgesia -1.6
Drug
Acthar 9.3
7,8-Dihydroneopterin 9.2
Fructose 8.7
Droxidopa 8.6
Lipitor 7.8
Visken 7.7
Lipitor 7.4
Lipitor 7.4
Dodecyl Sulfate 7.0
Rhamnose 6.0
Pyridoxal phosphate 6.0
Nitazoxanide 5.9
L-Ser 5.3
Tubocurarine 5.2
Pyridoxal 5.1
pyridoxal phosphate 5.0
NADH 4.8
Cilostazol 4.5
Pregabalin 4.4
Methylprednisolone 4.3
Galactose 4.1
lysine 4.0
Helium 3.9
citric acid 3.9
CoCl2 3.9
CoCl2 3.9
Vitamin B 3.9
Adenosine deaminase 3.7
NAG 3.7
Prednisolone 3.6
Glucagon 3.6
Fragment 3.6
Bupivacaine 3.6
AGG 3.5
THF 3.3
DFP 3.3
Asn 3.2
lactose 3.2
PFA 3.2
-deoxyadenosine 3.1
Ketoconazole 3.1
AraC 3.1
Infliximab 3.0
Capsicum 3.0
Infliximab 3.0
RFP 2.9
Serum albumin 2.9
niacin 2.9
Pronase 2.8
Gel 2.8
FeCl3 2.7
ALA 2.7
CTA 2.7
Bayer 2.5
VCR 2.5
Triclosan 2.5
Ginseng 2.5
Diurnal 2.4
vitamin E 2.4
NH3 2.4
Docetaxel 2.4
ABC 2.4
Leaf 2.3
Bifidobacterium 2.2
ADR 2.2
uPA 2.1
Biopolymers 2.1
CDP 2.0
L-tyrosine 2.0
Glutathione 1.8
Fluorescein 1.8
Alanine 1.7
CaCl2 1.5
CaCl2 1.5
Taxol 1.5
CaCl2 1.5
ascorbate 1.5
MRC 1.4
PCP 1.3
Fluorescein 1.3
more...
Enzyme
aldolase 13.2
glucose phosphomutase 13.2
fluorothreonine transaldolase 13.2
EC 4.1.2.21 13.2
tagatose 6-phosphate kinase 13.2
L-rhamnonate dehydratase 12.8
L-rhamnonate dehydratase 12.8
L-rhamnose 1-dehydrogenase 12.6
tagatose-6-phosphate kinase 12.6
gluconate dehydratase 12.4
4-hydroxy-2-oxoglutarate aldolase 12.3
galactonate dehydratase 12.3
L-fuculose 1-phosphate aldolase 12.3
rhamnulose-1-phosphate aldolase 12.2
lactaldehyde reductase 12.2
gamma-lactonase 12.2
3-hydroxyaspartate dehydratase 12.2
tagatose-bisphosphate aldolase 12.2
2-keto-3-deoxy-6-phosphogluconate aldolase 12.1
L-rhamnulose kinase 12.1
galactarate dehydratase 11.9
triokinase 11.9
propanediol dehydrogenase 11.8
oligoendopeptidase F 11.6
L-fuculokinase 11.6
KDOP synthase 11.6
lactate synthase 11.6
galactose-6-phosphate isomerase 11.6
dihydrocoumarin hydrolase 11.6
pyruvate aldolase 11.4
L-ribulose-5-phosphate 4-epimerase 11.4
tartronate semialdehyde reductase 11.4
trimethyllysine dioxygenase 11.3
vanillin dehydrogenase 11.2
deoxyribose-5-phosphate aldolase 11.2
2-keto-3-deoxygluconate kinase 11.2
alpha-ketoglutaric semialdehyde dehydrogenase 11.2
L-fucose isomerase 11.1
glucarate dehydratase 11.0
D-glucosaminate dehydratase 10.8
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase 10.8
trimethylamine N-oxide demethylase 10.8
2-oxo-3-deoxygalactonate kinase 10.8
lactoyl-CoA dehydratase 10.8
NeuAc synthase 10.8
lactaldehyde dehydrogenase 10.7
uronate dehydrogenase 10.6
L-arabonate dehydratase 10.6
D-xylonate dehydratase 10.6
SuyAB 10.6
ketohexokinase 10.5
6-phosphogluconate dehydratase 10.4
tauropine dehydrogenase 10.4
L-rhamnose isomerase 10.3
glycerate kinase 10.3
dihydroneopterin aldolase 10.1
triose-phosphate isomerase 10.1
SBPase 10.1
salicylaldehyde dehydrogenase 10.1
EC 2.7.1.90 10.0
lactaldehyde dehydrogenase 9.9
naphthalene dihydrodiol dehydrogenase 9.8
ferric leghemoglobin reductase 9.8
phosphoglucose isomerase 9.8
pseudouridylate synthase 9.7
phosphoglyceromutase 9.7
transaldolase 9.7
D-ribulokinase 9.6
threonine aldolase 9.5
PdxA 9.5
mannokinase 9.5
glyoxylate reductase 9.5
glyoxylate reductase 9.4
fructokinase 9.3
phosphofructokinase 9.3
hydroxyethylthiazole kinase 9.3
phosphopentomutase 9.3
dihydroxyacetone kinase 9.2
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9.2
fructose 1,6-bisphosphatase 9.1
more...
Compound
2-keto-4-hydroxyglutarate 12.2
Pyruvic oxime 12.2
2-keto-3-deoxy-6-phosphogluconate 12.1
C4H9NO3 11.8
C4H9NO3 11.6
hex-2-ulosonic acid 11.6
Rutamycin 11.6
fructose-1-phosphate 11.4
2-keto-3-deoxygluconate 11.4
L-lactaldehyde 11.3
deoxyribose-5-phosphate 11.2
D-Threonine 11.2
hept-2-ulose 11.2
HKP 11.2
dihydroxyacetone-phosphate 11.0
D-Glyceraldehyde 3-phosphate 10.8
Pantoate 10.7
Deoxyribose 10.6
hexaric acid 10.6
hexaric acid 10.6
hexaric acid 10.6
hexaric acid 10.2
HBPA 10.0
3-dehydroshikimic acid 9.9
C5H9NO2 9.8
C5H9NO2 9.8
15S-hydroxyeicosatrienoic acid 9.8
hept-2-ulose 9.7
Galactonate 9.7
2-(methylthio)ethanol 9.6
L-Ribulose 9.6
Sedoheptulose 9.5
D-ribose-5-phosphate 9.5
hexaric acid 9.5
D-Tagatose 9.4
Coniine 9.3
2-methylpentanoic acid 9.3
2-oxoadipate 9.2
D-Glyceraldehyde 9.1
FDP 9.1
6-phosphogluconate 9.1
Chloral 9.0
3-aminopropanal 9.0
D-Glyceraldehyde 8.9
Coniferaldehyde 8.8
Cytochalasin A 8.8
Aldol 8.8
4-hexenoic acid 8.8
fructose-6-P 8.8
sedoheptulose 7-phosphate 8.7
Fructose 8.7
ribose-5-phosphate 8.6
1-hydroxy-2-naphthoic acid 8.6
Galacturonic acid 8.5
erythrose-4-phosphate 8.5
D-erythrose 8.4
Glyceraldehyde 8.4
malyl-CoA 8.4
Ribose 5-phosphate 8.4
6-phosphogluconolactone 8.3
Xylulose 8.3
FK463 8.3
Dihydroxyacetone 8.3
2-amino-3-ketobutyrate 8.3
F6P 8.2
F6P 8.2
hexitol 8.2
benzenesulfonyl chloride 8.2
hexitol 8.2
L-Arabinose 8.2
N-acetylmannosamine 8.1
2-naphthaldehyde 8.1
hexitol 8.1
Acetol 8.1
L-alpha-lysophosphatidylcholine 7.9
D-Fructose 7.9
Glycidol 7.8
4-hydroxy-2-butanone 7.8
2-oxobutyrate 7.8
Phosphorylase a 7.8
more...