Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.2.13 (
aldolase
)
3,461
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Kidney tissue enzyme patterns from patients with calcium oxalate stone disease were compared to enzyme patterns from healthy and inflamed human kidneys. In the case of oxalate stone disease there was a significantly decreased activity of the glycolytic enzyme
aldolase
, resulting in a cumulation of oxaloacetate and of
oxalic acid
. This decrease of the
aldolase
activity does not completely reveal the cause of calcium oxalate stones but provides a new aspect to the disease.
...
PMID:Calcium oxalate stone disease: congenital defect of metabolism? 100 30
