Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.2.13 (
aldolase
)
3,461
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Fructose-bisphosphatase-deficient mutants of mucoid Pseudomonas aeruginosa were isolated by
ethyl methanesulfonate
mutagenesis using gluconate as the nonpermissive substrate, and all the sixty isolates possessed 10-30% of the parental enzyme activity. The mutants had low levels of fructose-biphosphate
aldolase
activity and could not normally synthesize alginate from any substrate except on Pseudomonas isolation agar plates. The results suggest the essentiality of fructose bisphosphatase activity for the growth or survival of P. aeruginosa and a probable linkage of genes controlling this enzyme with those of fructose bisphosphate aldolase and alginate biosynthesis.
...
PMID:Fructose-bisphosphatase-deficient mutants of mucoid Pseudomonas aeruginosa. 254 76
