Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.2.13 (aldolase)
3,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A new metabolic reaction of the aldolase condensation between formic acid and acetaldehyde proceeding with the formation of milk acid is detected in the liver of rats. Milk acid has been determined by chemical, enzymic and autoradiographic methods. Homogeneous preparations of the enzyme which catalyzes the mentioned reactions and is called lactate synthase are obtained in the crystalline form. The method for obtaining the lactate synthase from the rat liver is described as well as certain properties of the lactate synthase.
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PMID:[Various metabolic reactions of formate in animal tissues]. 362 27