Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.2.13 (aldolase)
 3,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1. The experiment investigated the effects of psychotropic drugs on enzymes in vitro.2. Chlorpromazine inhibits mitochondrial malate dehydrogenase in concentrations of 1.4x10(-4)M and above. No effect was observed below this concentration.3. A sharp inflection in the [unk]/drug plot was also seen with chlorpromazine (1.4 x 10(-4)M), trifluoperazine (1 x 10(-5)M), prochlorperazine (1 x 10(-4)M), and amylobarbitone (8 x 10(-3)M) acting on rat brain (Na(+)-K(+)-) Mg(++)-ATPase and with chlorpromazine (10(-4)M) and imipramine (3 x 10(-4)M) acting on aldolase.
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PMID:The influence of psychotropic drugs on aldole, mitochondrial malic dehydrogenase and Mg++na+K+ adenosine triphosphatase. 424 60