Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:4.1.2.13 (aldolase)
 3,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Associated adenoviral, staphylococcus, and streptococcus infection was studied in the cultures of cells HEp-2 and PAO. Under conditions of monoinfection the cell culture largely inhibited the reproduction of staphylococci, and failed to influence the streptococci. In double and triple associated infections staphylococci overcame the inhibitory action of the cell culture. The pathogenic properties of cocci (plasma coagulation, hemotoxic properties) grown in the cell culture both under conditions of monoinfection, and in associations, failed to change. In double and triple associated infections adenoviruses did reproduce, but in lower titre than in monoinfection. Under conditions of mixed infection cocci penetrated and reproduced in the cell cytoplasm more intensively than in monoinfection. The cytopathic action was determined by viral associate, and was identical by its character to adenoviral monoinfection. A statistically significant increase in the activity of aldolase and transaminase enzymes was noted in mixed infection. The changes in the enzyme activity proved to depend on the character of the associations studied.
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PMID:[Experimental study of combined staphylococcal, streptococcal and adenovirus infections in tissue culture]. 20 35

Comparative data concerning enzyme activities of central metabolic pathways in pathogenic staphylococcus strains, containing and not containing plasmids of resistance to different antibiotics has been presented. An increase in the activity of key enzymes of glycolytic pathway: 6-phosphofructokinase, fructose-1,6-biophosphate aldolase, lactate dehydrogenase, and a decrease in the activity of enzymes of the pentose phosphate cycle: glucose-6-phosphate dehydrogenase in antibiotic resistant strains, were defined.
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PMID:[Activity of key enzymes of the glycolytic and pentose phosphate pathways in plasmid-containing Staphylococci]. 875

Decrease in intensity of lactate accumulation and activity of glycolytic enzyme such as: phosphofructokinase, fructose-1,6-bisphosphate aldolase, pyruvate kinase found in staphylococcus of the second group isolated at vaginosis in comparison with staphylococcus of the third group isolated at vaginosis and concomitant additional infection pathology as well in comparison with staphylococcus of the first control group. Minimal inhibitory effect (MIA) and increase of enzyme activity of pentosephosphate ways such as: glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, transketolase testify to an intensification pentose-phosphate ways and decrease in activity of found the second groups staphylococcus isolated at vaginosis in comparison with of the in third group isolated at vaginosis and additional infection pathology as well as in comparison with the first control group staphylococcus isolated at normal state of UGT.
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PMID:[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]. 1925 43