Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.6 (CAD)
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Human Gene/Protein
left-right determination, factor B 12.8
ALCOHOL DEHYDROGENASE 2 12.8
CAD 12.8
C5orf38 11.8
DFF40 11.5
CAD protein 11.5
ZNF484 11.2
CAM 10.9
PDCD8 10.8
Ras-related protein Rab-7b 10.8
INPP4B protein 10.5
PFAAP5 10.5
Collagenase 3 10.5
JPD 10.5
CYP27C1 10.5
ICAD 10.3
MRPL33 10.2
DFF35 10.2
JPO1 10.2
PIGY 10.0
SSR4 9.8
teratocarcinoma-derived growth factor 9.8
PIGC 9.8
NBEAL1 9.8
DFFB 9.8
DLAD 9.8
caspase-activated DNase 9.7
DTYMK 9.6
NANS 9.6
CMPK1 9.6
Wol 9.6
BFAR 9.6
DMGDH 9.5
NADH5 9.5
C17orf32 9.5
Staphylococcal nuclease domain-containing protein 1 9.5
complement C4B 9.5
CCDC115 9.5
EIF6 9.5
P2RX1 9.4
synaptotagmin 5 9.4
Elongation factor 1-alpha 9.4
N-6 adenine-specific DNA methyltransferase 1 9.4
CTPS2 9.4
PSMD12 9.4
CCTA 9.3
IPS 9.3
LEFTY B 9.2
protein phosphatase 1A 9.2
IRG1 9.1
Argininosuccinate synthase 9.1
CRKL protein 9.1
DNase gamma 9.1
STRN 9.0
CENP-L 9.0
Dehydrodolichyl diphosphate synthase 9.0
CAD4 9.0
NUS1 8.9
palmdelphin 8.9
Rheb2 8.9
PHACTR1 8.9
interleukin 6 signal transducer 8.8
ring finger protein 213 8.8
Caspase-activated DNase 8.7
CENP-Q 8.7
CGL-2 8.7
MCT6 8.7
PRPS2 8.7
FRP1 8.7
TZP 8.7
POLD4 8.6
SLC44A1 8.6
EF1a 8.6
FOLR3 8.6
PGAP1 8.6
CIDE-B 8.6
choline/ethanolamine phosphotransferase 1 8.6
PSPH 8.6
CIDEB 8.6
CENP-O 8.6
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Disease
Skin expander 12.8
Solitary Pulmonary Nodules 11.2
Non-ST elevation myocardial infarction (NSTEMI) 10.8
CAM 10.7
Coronary atheroma 10.5
Premature graying 9.8
IPS 9.7
Anabolic Steroids 9.5
JPD 9.5
coronary artery disease 9.5
Single vessel disease 8.8
IHG 8.8
Left main coronary artery disease 8.8
inflammatory polyarthropathy 8.7
Zimmermann-Laband syndrome 8.7
STL 8.7
Triple vessel disease 8.6
Hyperapobetalipoproteinemia 8.6
Postoperative myocardial infarction 8.6
Aortic atherosclerosis 8.4
Chronic actinic dermatitis 8.2
A-V malformation 8.1
GLC3 7.9
Stable angina 7.7
Miller syndrome 7.6
FIH 7.6
LUNG 7.6
CAE 7.5
Mycobacterium abscessus infection 7.5
CND 7.4
CAE 7.4
Coronary artery stenosis 7.3
Heterozygous familial hypercholesterolemia 7.3
PAL 7.3
CTPA 7.3
lipoprotein disorder 7.1
Primary congenital glaucoma 7.1
Q wave MI 7.1
AV reentrant tachycardia 7.0
Stress cardiomyopathy 6.9
Coronary artery calcification 6.9
Cystic adventitial disease 6.8
PLAT 6.8
chest pain syndrome 6.8
STEMI 6.7
CASS 6.7
lipoproteinemia 6.7
LAD 6.6
SVD 6.6
first degree atrioventricular block 6.6
chronic stable angina 6.6
edentulous 6.6
IgA pemphigus 6.5
HEART 6.4
SVD 6.4
MD1 6.3
FMD 6.1
PAPA 6.1
Endometrioma 6.1
erythrodermia 6.1
KCS 6.0
diphyllobothriasis 6.0
Postinfarction 6.0
Libman-Sacks endocarditis 5.9
orotic aciduria 5.9
Acute coronary syndrome 5.9
IMT 5.7
Familial combined hyperlipidemia 5.7
unstable angina 5.7
mineral deficiency 5.6
LDS 5.6
AOS 5.6
idiopathic dilated cardiomyopathy 5.6
tooth wear 5.6
coronary artery spasm 5.5
hypoalphalipoproteinemia 5.4
AN2 5.4
Angle Class II 5.4
dyserythropoietic anemia 5.3
DVD 5.3
more...
Symptom
PAIN 6.7
diastolic murmurs 6.6
atypical chest pain 6.5
sighing 6.2
monoplegia 6.0
asynergy 5.8
angina 5.5
giddiness 5.2
giddiness 5.1
chest pain 5.0
Halo 5.0
Scratch 4.2
Spots 4.0
Fluctuation 3.6
spasm 3.5
forgetfulness 3.4
CSR 3.4
exertional angina 3.3
general problem 3.1
leg pain 2.8
abnormal gait 2.7
fatigue 2.6
fasciculation 2.5
discomfort 2.3
HSA 2.3
discomfort 2.2
distraction 2.2
menopausal symptoms 2.1
exertional dyspnea 2.1
alexithymia 2.1
neck pain 1.9
acute abdominal pain 1.9
twitching 1.8
blurred vision 1.8
heartburn 1.8
flushing 1.8
skin irritation 1.7
tense 1.7
dizziness 1.6
tachypnea 1.5
shortness of breath 1.5
overweight 1.5
ENT 1.4
shoulder pain 1.4
acute abdomen 1.2
dyspnea 1.2
functional recovery 1.1
hemiplegia 0.9
back pain 0.8
collapse 0.8
acute stress 0.6
syncope 0.6
nausea 0.6
wheezing 0.6
paresthesia 0.5
low back pain 0.5
constipation 0.5
pain 0.5
cachexia 0.4
hunger 0.3
hepatomegaly 0.3
headache 0.2
starvation 0.2
spasticity 0.2
exhaustion 0.1
anorexia 0.1
arthralgia 0.0
acidity -0.1
weakness -0.1
dystonia -0.2
anesthesia -0.2
hypothermia -0.3
respiratory distress -0.4
splenomegaly -0.5
seizures -0.5
insomnia -0.6
agitation -0.7
erythema -0.9
abdominal pain -1.1
vomiting -1.1
more...
Drug
CAM 10.6
Sarpogrelate hydrochloride 9.1
Ticlopidine hydrochloride 8.1
Tulobuterol 8.0
Aggrastat 7.4
Trenbolone acetate 7.4
Hirulog 7.0
CER 6.3
Teniposide 6.2
Basiliximab 6.1
Basiliximab 6.1
CA-074 6.0
Vindesine 6.0
Trandolapril 5.9
Vindesine 5.9
Ipriflavone 5.8
KAN 5.7
Eptifibatide 5.7
Acamprosate 5.5
Clopidogrel 5.5
CFX 5.5
Darbepoetin alfa 5.4
Podophyllum 5.4
CTA 5.2
Poloxamer 5.1
Rosuvastatin 5.0
Argatroban 5.0
CVA 4.9
Ranolazine 4.9
Ranolazine 4.9
EMB 4.8
Epoetin 4.7
ID2 4.7
Apixaban 4.6
Abciximab 4.6
CPZ 4.5
Fondaparinux 4.5
Perindopril 4.5
Dalteparin 4.3
Pemetrexed 4.2
Cilostazol 4.1
MDM 4.1
ROC 4.1
LCM 4.0
LCM 4.0
THA 4.0
AHF 4.0
Papaverine 3.9
CSI 3.9
PFA 3.8
AMC 3.6
Digitalis 3.6
Triad 3.5
nitroglycerin 3.5
PDL 3.5
Everolimus 3.4
TEL 3.2
CIA 3.2
AGG 3.2
Android 3.2
TAC 3.2
Pravastatin 3.1
Irinotecan 3.1
Fraction 3.1
Prednisone 2.8
AraC 2.8
Etoposide 2.7
Aloe 2.6
citric acid 2.5
Vitamin B12 2.5
Imatinib 2.5
niacin 2.5
CCL 2.5
Alanine 2.4
Glycyrrhiza 2.3
BH4 2.2
Adriamycin 2.2
GEO 2.2
ADM 2.2
Bayer 2.2
more...
Enzyme
CAD 12.8
CAD 12.8
trans-aconitate 3-methyltransferase 12.8
CAD 12.8
dihydroorotase 10.4
EC 1.1.1.219 9.6
aspartate transcarbamylase 9.1
cinnamoyl-CoA reductase 8.6
caffeate O-methyltransferase 8.4
PrpD 8.4
4CL 8.3
oxaloacetate acetylhydrolase 8.1
CPS 7.8
aryl-alcohol dehydrogenase 7.8
FGAM synthetase 7.8
shikimate dehydrogenase 7.6
DHOdehase 7.4
carbamoylphosphate synthetase 7.3
fatty acyl-CoA reductase 6.9
PAL 6.7
benzyl alcohol dehydrogenase 6.6
PAL 6.6
CSAD 6.5
DNase II 6.4
cinnamate 4-hydroxylase 6.2
methylenetetrahydrofolate dehydrogenase 6.1
amidophosphoribosyltransferase 5.9
PPH 5.9
guanidinoacetate methyltransferase 5.7
arginine kinase 5.6
methylenetetrahydrofolate dehydrogenase 5.6
glycine N-methyltransferase 5.5
glycine amidinotransferase 5.5
dihydroorotate dehydrogenase 5.4
dihydroorotate dehydrogenase 5.4
aconitase 5.4
MDH 5.2
MDH 5.1
alanyl-tRNA synthetase 5.1
glutaryl-CoA dehydrogenase 5.1
argininosuccinate synthetase 5.0
inositol 3-kinase 5.0
caspase-6 4.9
NCP 4.9
caspase-6 4.8
CPL 4.8
meprin 4.7
CCS 4.6
LTA4 hydrolase 4.6
DNase 4.6
glycerophosphate acyltransferase 4.5
endothelin-converting enzyme 4.5
cellulose synthase 4.5
isocitrate lyase 4.5
LPL 4.4
ACAT 4.3
PME 4.3
glutaminase 4.2
AGT 4.2
CFI 4.2
TMT 4.2
methionine synthase 4.1
PTA 4.1
PHD 4.1
HSD 4.1
caspase-7 4.0
methionine synthase 4.0
lactic acid dehydrogenase 4.0
caspase-7 4.0
lactic acid dehydrogenase 3.9
dehydroascorbate reductase 3.7
PRA 3.7
flavin-containing monooxygenase 3.7
estrogen sulfotransferase 3.7
HDR 3.6
ACE 3.5
cellulose synthase 3.5
caspase-9 3.4
cholesterol acyltransferase 3.4
E-2 3.4
more...
Compound
C7H13N3O4 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C11H20N2O3 12.8
C7H13N3O4 12.8
C15H20N2O4S 12.8
PF 19 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C11H20N2O3 12.8
C15H20N2O4S 12.8
C7H13N3O4 12.8
C7H13N3O4 12.8
C15H20N2O4S 11.8
C11H20N2O3 11.8
C7H14O5 11.8
C17H22N2O5 11.8
C11H20N2O3 11.8
C10H19N3O4 11.2
C19H20N2O3 11.2
Caldine 11.2
C3H5NO2 10.8
Cinnamyl alcohol 10.7
CAM 9.8
PALA 9.8
Zirconia 9.3
Kanamycin A 9.2
itaconic acid 9.0
2-oxopropanamide 8.9
Chromanol 293B 8.9
carbamyl phosphate 8.7
Acetohexamide 8.6
Coniferaldehyde 8.5
Mechlorethamine 8.4
Aurin 8.3
Cicutoxin 8.2
MINA 8.1
1,5-pentanediamine 7.8
Galactan 7.7
1,3-oxazolidin-2-one 7.6
MHT 7.5
Anacardic acid 7.0
Josamycin 7.0
Josamycin 6.9
Josamycin 6.9
PCI 6.7
UDMA 6.7
CONV 6.6
PRPP 6.6
Escin 6.6
Escin 6.5
Ajmaline 6.5
Sooner 6.4
FBF 6.3
Diethyl pyrocarbonate 6.3
COI 6.2
vinyl carbamate 6.2
Hydrocortisone acetate 6.2
IDC 6.1
Stains-all 6.1
UMP 6.0
DCM 6.0
MMD 5.9
MOD 5.9
Triphosphate 5.9
1,4-butanediamine 5.9
SHM 5.8
Bis-GMA 5.7
DDC 5.7
Ergonovine 5.6
DDC 5.6
Lignin 5.6
Methylparaben 5.5
1,6-hexanediamine 5.5
TBS 5.5
COA 5.5
more...