Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.1.6 (
CAD
)
4,420
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CAD
4384
CAM
1285
Sep
283
Mol
151
HDL
96
ANOVA
90
IPS
85
insulin
60
ICAD
53
MRI
50
DFF40
49
caspase-3
48
COI
42
polypeptide
37
fused
37
CPS
37
C-reactive protein
34
ACS
32
TZP
31
Gen
30
p53
29
PCI
28
ACE
25
PAL
24
ATP
24
Lp(a)
23
CRP
23
DNase
23
caspase-activated DNase
22
LAD
22
fibrinogen
21
PAD
21
endoplasmic reticulum
18
NMR
18
endonuclease
18
Pol
17
E-cadherin
17
TNF
16
IL-6
16
collagen
16
STIM1
16
CAD protein
14
Bcl-2
14
apolipoprotein
14
caspase-9
13
ESI
13
cytochrome c
12
caspase-8
12
HLA
12
COMT
11
MGC
10
CHD
10
CNC
10
aconitase
10
epithelial cadherin
10
LDL receptor
10
ATPase
10
lactate dehydrogenase
10
hemoglobin
10
COPD
9
AMP
9
peroxidase
9
calcium channel
9
AKT
9
CRAC
9
ECD
9
cytokine
9
C18
9
renin
9
lipoprotein lipase
9
IL-10
9
tyrosine hydroxylase
9
albumin
9
histone
8
TOF
8
MMP-9
8
ubiquitin
8
SDS
8
ICAM-1
8
catenin
8
plasminogen activator inhibitor-1
8
COII
8
FMD
8
A-I
8
CO2
8
telomeric
8
HSD
8
nodal
8
mTOR
8
alcohol dehydrogenase
8
PVD
8
Fas
7
apolipoprotein B
7
interleukin-6
7
chronic renal failure
7
adenosine receptor
7
vascular cell adhesion molecule-1
7
carbamoylphosphate synthetase
7
GAPDH
7
duo
7
c-Myc
7
grit
7
hole
7
PI3K
7
adiponectin
7
endonuclease G
7
BDE
6
PARP
6
apolipoprotein E
6
TNF-alpha
6
HMG-CoA reductase
6
cholesteryl ester transfer protein
6
MAP kinase
6
reserved
6
superoxide dismutase
6
methyltransferase
6
AAA
6
ACC
6
Cad
6
apoE
6
ADP
6
IL-8
6
GPIIb
6
VIM
6
matrix metalloproteinase
6
CAE
6
PrP
6
transporter associated with antigen processing
6
PLA
6
SAP
6
tumor necrosis factor
6
ICD
6
GSH
6
IFN
6
endothelin-1
6
cadherin
6
SBP
6
osteogenic
6
threonine
5
FAS
5
Hua
5
PTEN
5
CCTA
5
DFF35
5
ARB
5
leptin
5
DNase II
5
myeloperoxidase
5
vascular endothelium
5
Smac
5
LPS
5
reductase
5
nitric oxide synthase
5
thymus
5
endothelial nitric oxide synthase
5
p300
5
Hip
5
ATM
5
nov
5
MYB
5
more...
Disease
coronary artery disease
4388
CAM
1285
atherosclerosis
224
myocardial infarction
210
diabetes
190
hypertension
148
cancer
126
cardiovascular disease
107
ischemia
99
myocardial ischemia
96
stroke
90
IPS
85
tumor
83
plaque
77
edentulous
65
depression
64
heart failure
58
obesity
51
type 2 diabetes
46
unstable angina
45
acute myocardial infarction
41
breast cancer
40
hypercholesterolemia
37
SEM
36
congestive heart failure
36
heart disease
34
coronary heart disease
32
hyperlipidemia
30
dyslipidemia
29
PAL
24
LAD
22
metabolic syndrome
21
lung cancer
20
vascular disease
19
cold
18
chronic renal failure
17
cardiomyopathy
17
idiopathic dilated cardiomyopathy
17
Alzheimer's disease
17
renal disease
15
systemic lupus erythematosus
14
chronic obstructive pulmonary disease
14
STL
13
renal failure
13
STEMI
13
fits
13
dilated cardiomyopathy
12
leukemia
12
peripheral vascular disease
12
abdominal aortic aneurysm
12
anemia
11
periodontitis
11
HIV
11
dysplasia
11
aortic stenosis
11
chronic stable angina
10
scoliosis
10
hepatocellular carcinoma
10
adenocarcinoma
10
tumorigenesis
10
mitral regurgitation
10
dementia
10
COPD
9
neuroblastoma
9
metastases
9
IMT
9
tumor progression
9
Parkinson's disease
9
pulmonary embolism
8
SDS
8
pulmonary hypertension
8
FMD
8
FMD
8
carcinoma
8
Anterior
7
brucellosis
7
colorectal cancer
7
coronary artery spasm
7
transient ischemic attack
7
epilepsy
7
Hodgkin's disease
7
GSH
7
osteoporosis
7
renal insufficiency
7
prostate cancer
7
cerebral ischemia
6
Posterior
6
lymphoma
6
SPM
6
carcinogenesis
6
ICD
6
atherosclerotic cardiovascular disease
6
rheumatoid arthritis
6
coronary occlusion
6
ventricular hypertrophy
6
hyperglycemia
6
hyperinsulinemia
6
arteriosclerosis
6
essential hypertension
6
AAA
6
arthrodesis
6
hypertrophic cardiomyopathy
6
MCF
6
squamous cell carcinoma
6
IBM
6
tooth loss
6
CAE
6
CAE
6
cytomegalovirus
6
valvular heart disease
6
SLE
6
autonomic neuropathy
5
CCD
5
fatty liver
5
CCD
5
mental illness
5
FAS
5
colon cancer
5
lung disease
5
ATM
5
tooth wear
5
cirrhosis
5
obstructive sleep apnea
5
major depressive disorder
5
sleep apnea
5
alcohol abuse
5
melanoma
5
arthritis
5
type 1 diabetes
5
multiple myeloma
5
glucose intolerance
5
left bundle branch block
5
dehydration
5
tumor growth
5
lupus
5
proteinuria
5
hyperhomocysteinemia
5
aggression
5
retinopathy
5
Syndrome
4
gastric cancer
4
SVD
4
infectious diseases
4
SVD
4
Plaque
4
emphysema
4
aggressiveness
4
SCD
4
Still
4
HDL2
4
AIDS
4
Chlamydia
4
cardiovascular risk factor
4
West
4
CEM
4
hypoglycemia
4
cerebral infarction
4
myocarditis
4
NLS
4
osteoarthritis
4
more...
Symptom
angina
130
chest pain
79
pain
51
fatigue
45
discomfort
16
discomfort
15
anesthesia
13
spasm
12
overweight
10
dyspnea
9
headache
9
seizures
8
atypical chest pain
8
collapse
7
distraction
6
weakness
5
nausea
5
asynergy
5
dizziness
4
functional recovery
4
starvation
4
flushing
3
back pain
3
anorexia
2
ENT
2
low back pain
2
vomiting
2
shortness of breath
2
neck pain
2
syncope
2
hypothermia
2
Halo
2
leg pain
2
respiratory distress
2
exertional dyspnea
2
constipation
2
exhaustion
2
HSA
2
acidity
2
abdominal pain
2
diarrhea
2
acute abdominal pain
1
hunger
1
acute stress
1
alexithymia
1
Scratch
1
sighing
1
tense
1
paresthesia
1
diastolic murmurs
1
cachexia
1
fasciculation
1
forgetfulness
1
Fluctuation
1
skin irritation
1
exertional angina
1
acute abdomen
1
blurred vision
1
arthralgia
1
wheezing
1
giddiness
1
hepatomegaly
1
insomnia
1
spasticity
1
PAIN
1
twitching
1
monoplegia
1
dystonia
1
erythema
1
giddiness
1
CSR
1
agitation
1
Spots
1
heartburn
1
tachypnea
1
tremor
1
Welt
1
cough
1
menopausal symptoms
1
shoulder pain
1
abnormal gait
1
hemiplegia
1
splenomegaly
1
general problem
1
Drug
CAM
1285
Cardiovasc
118
ROC
18
nitroglycerin
14
Monit
12
lysine
8
citric acid
8
CTA
7
Clopidogrel
7
ascorbate
5
MAP
5
ROS
5
ENT
5
vitamin E
4
Dermatol
4
Adriamycin
3
niacin
3
Dial
3
Nephron
3
Fraction
3
IFN-gamma
3
ampicillin
3
CER
3
ADM
2
IL-2
2
PTH
2
Leaf
2
CTX
2
SiO2
2
caffeine
2
PFA
2
NH3
2
Alanine
2
CVA
2
ZnO
2
CSF
2
Rosuvastatin
2
Glutathione
2
THA
2
Angiotensin II
2
Gel
2
PCB
2
AMC
2
Nephron
2
Imatinib
2
TAC
2
Irinotecan
1
TAT
1
Asn
1
HCH
1
TMS
1
EPA
1
Forskolin
1
Basiliximab
1
Ranolazine
1
TiO2
1
BH4
1
LCM
1
NADH
1
p75
1
AraC
1
CSI
1
Perindopril
1
Fondaparinux
1
Fragment
1
Glycyrrhiza
1
Eptifibatide
1
Pravastatin
1
Cilostazol
1
Bayer
1
ABC
1
Dalteparin
1
Digitalis
1
EMB
1
Ranolazine
1
ID2
1
Argatroban
1
Parkin
1
CIA
1
Spectrum
1
ETA
1
lactose
1
DM1
1
TEL
1
CaCl2
1
Triad
1
LCM
1
Ticlopidine hydrochloride
1
DNase I
1
MDS
1
Darbepoetin alfa
1
Triclosan
1
Aggrastat
1
Sarpogrelate hydrochloride
1
CPR
1
CDP
1
AGG
1
CFX
1
Everolimus
1
EPI
1
Rituximab
1
Parkin
1
Vitamin A
1
Basiliximab
1
CPZ
1
Nitric Oxide
1
Teniposide
1
CTX
1
KAN
1
Podophyllum
1
Vindesine
1
G-CSF
1
Hirulog
1
Ipriflavone
1
Spectrum
1
CaCl2
1
CCL
1
CaCl2
1
GEO
1
AHF
1
MIL
1
Pemetrexed
1
Mutagen
1
Vitamin B12
1
ADR
1
uPA
1
Epoetin
1
Papaverine
1
Etoposide
1
MDM
1
Trenbolone acetate
1
Paraffin
1
G418
1
Acamprosate
1
Trandolapril
1
Tulobuterol
1
Apixaban
1
PDL
1
Prednisone
1
Vindesine
1
PTC
1
CTX
1
Aloe
1
Poloxamer
1
Android
1
CA-074
1
ACT
1
Abciximab
1
Enzyme
CAD
4420
CAD
4384
CAD
4384
aspartate transcarbamylase
66
dihydroorotase
54
caspase-3
40
CPS
40
ACS
32
ACE
29
PAL
28
DNase
25
PAL
24
protein kinase
21
mitogen-activated protein kinase
19
ERK
18
endonuclease
18
4CL
14
peroxidase
14
focal adhesion kinase
13
ATPase
12
lactate dehydrogenase
11
caspase-9
11
aconitase
10
caspase-8
9
alcohol dehydrogenase
9
renin
9
lipoprotein lipase
9
cytochrome oxidase
8
HSD
8
glyceraldehyde-3-phosphate dehydrogenase
8
tyrosine hydroxylase
8
PARP
7
dihydrofolate reductase
7
trypsin
7
superoxide dismutase
7
carbamoylphosphate synthetase
7
elastase
7
luciferase
6
RNA polymerase
6
catalase
6
thrombin
5
creatine kinase
5
glutaminase
5
tissue plasminogen activator
5
DNase II
5
thromboplastin
5
protein kinase C
4
proteasome
4
phosphoenolpyruvate carboxykinase
4
cinnamoyl-CoA reductase
4
MAP
4
LPL
4
granzyme B
4
aldehyde dehydrogenase
4
MDH
4
PTA
4
malate dehydrogenase
4
MDH
4
shikimate dehydrogenase
4
AMPK
4
collagenase
3
reverse transcriptase
3
methylenetetrahydrofolate reductase
3
RNase
3
ribonucleotide reductase
3
MMP
3
APC
3
citrate synthase
3
RNase
3
alkaline phosphatase
3
PRA
3
alanine aminotransferase
3
arginine kinase
3
dihydroorotate dehydrogenase
3
isocitrate dehydrogenase
3
argininosuccinate synthetase
3
ribonucleotide reductase
3
methylenetetrahydrofolate reductase
3
dihydroorotate dehydrogenase
3
cholesterol acyltransferase
3
isocitrate dehydrogenase
3
adenylate cyclase
3
isocitrate lyase
3
deoxyribonuclease
2
PHD
2
CCS
2
PPH
2
hexokinase
2
CaMKII
2
transcriptase
2
triphosphatase
2
cellulose synthase
2
glutathione S-transferase
2
phosphatidylinositol 3-kinase
2
cellulose synthase
2
TMT
2
NOS
2
AMPK
2
endothelin-converting enzyme
2
caspase-6
2
caspase-7
2
AMP-activated protein kinase
2
lipase
2
MEK
2
meprin
2
MMP-3
2
ornithine decarboxylase
2
histidine kinase
2
CD10
2
urokinase-type plasminogen activator
2
transglutaminase
2
deoxyribonuclease
2
gamma-glutamyl transpeptidase
2
AGT
2
beta-glucosidase
2
carbonic anhydrase
2
NADPH oxidase
2
aspartate aminotransferase
2
kinesin
2
micrococcal nuclease
2
choline acetyltransferase
2
beta-glucuronidase
2
NADPH oxidase
2
methionine synthase
2
topoisomerase
2
enolase
2
topoisomerase
2
succinate dehydrogenase
2
tyrosinase
2
urease
2
methionine synthase
2
caspase-6
2
beta-glucosidase
2
adenosine deaminase
2
cinnamate 4-hydroxylase
2
chitinase
2
flavin-containing monooxygenase
2
CFI
2
caspase-7
2
adenosine deaminase
2
PKG
1
paraoxonase
1
cathepsin B
1
NO synthase
1
aldose reductase
1
glycerophosphate acyltransferase
1
hypoxanthine-guanine phosphoribosyltransferase
1
E-2
1
EC 1.1.1.219
1
glyceraldehyde-3-phosphate dehydrogenase
1
caspase-1
1
monoamine oxidase
1
glutamine synthetase
1
KAT
1
asparaginase
1
glutathione peroxidase
1
PDK1
1
diamine oxidase
1
methylenetetrahydrofolate dehydrogenase
1
ADH
1
more...
Compound
CAM
1290
Dec
294
DNA
244
Clin
235
Cardiol
158
titanium
122
water
111
calcium
94
pyrimidine
89
pyrimidine
89
glucose
64
oxygen
58
phosphate
49
Zirconia
45
COI
42
acetate
38
itaconic acid
34
ACS
32
carbamyl phosphate
32
ACS
32
PALA
32
PCI
28
sodium
26
creatinine
25
ATP
24
nitrogen
23
ammonia
23
hydrogen
23
cobalt
22
nitric oxide
21
zinc
20
silicon
19
glutamine
18
arginine
18
aluminum
17
chromium
16
Cinnamyl alcohol
16
ethanol
16
TNF
16
UTP
16
homocysteine
15
acetonitrile
15
Lithium
14
Cholesterol
14
serine
14
Phe
14
salt
14
uridine
14
His
14
urea
13
methanol
12
copper
12
Asp
12
threonine
12
cysteine
12
leucine
11
SDS
10
CO2
10
UMP
10
nickel
10
lysine
10
glutamate
10
alcohol dehydrogenase
9
Lignin
9
alanine
9
ASA
9
galactose
9
NH2
9
AMP
9
ammonium
9
cAMP
9
aspartic acid
9
iron
9
DCM
8
sulfate
8
TOF
8
DAD
8
potassium
8
aldehyde
8
acetic acid
7
SPM
7
aldehyde
7
EDTA
7
ADP
7
phosphoric acid
7
MOD
7
asparagine
6
methionine
6
EDTA
6
SPD
6
AAA
6
ADP
6
PEG
6
UDP
6
GSH
6
Gly
6
silver
6
ADP
6
Mg2+
6
Angiotensin II
6
dicarboxylic acid
6
MTT
6
GSH
6
CoA
6
A 3
6
tyrosine
6
CAP
6
nitrate
6
glutamic acid
5
Insulin
5
Adriamycin
5
PEG
5
AHA
5
Adenosine
5
trifluoroacetic acid
5
N-acetylcysteine
5
vinyl
5
trifluoroacetic acid
5
trifluoroacetic acid
5
Pac
5
Ile
5
trifluoroacetic acid
5
trifluoroacetic acid
5
acetone
4
MAP
4
methane
4
DDC
4
cGMP
4
barium
4
boron
4
HIS
4
DBP
4
SAD
4
CaO
4
tungsten
4
TCP
4
PPO
4
proline
4
COS
4
MgO
4
TCA
4
ADR
4
iodine
4
6-12
4
Uridine
4
glycerol
4
THE
4
TCP
4
Ascorbic acid
4
DBP
4
L-DOPA
4
Dipyridamole
4
TCP
4
aldosterone
4
GTP
4
retinoic acid
4
Dipyridamole
4
acrylonitrile
4
Amiodarone
4
TCP
4
more...