Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.6 (CAD)
 4,420 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Emotional distress and interpersonal stress are extremely common in patients after myocardial infarction and typically lessen over several months. However, it is important for physicians to screen patients with CAD for certain conditions that may need further assessment and possible treatment by a mental health professional. The examination of the patient with CAD involves assessment of psychological functioning, including the patient's level of denial, anxiety, and depression; the presence of panic anxiety or depressive disorder; and neuropsychological functioning, including memory and concentration. Evaluation for the presence of persistent or excessive interpersonal strife, marital conflict, and sexual dysfunction is also important. Those with symptomatic anxiety, depression, or social or sexual dysfunction should be referred to a mental health professional who has expertise in working with CAD patients and is knowledgeable about a variety of psychosocial and psychopharmacological treatments. Patients with CAD who are unable to modify their cardiovascular risk factors satisfactorily after guidelines are clearly articulated should be referred to a center designed to help patients identify the obstacles to behavior change and to facilitate and maintain long-term adherence to these changes. Patients with CAD who are physiologically able to work but have marked work stress or a marked reluctance to return to work should be evaluated by a mental health professional.
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PMID:Prevention of disability due to cardiovascular diseases. 815 78

Treatment of psychosocial/emotional distress as a strategy for diminishing chest pain in such patients remains entirely unutilized in standard care. Sixty-three patients with known or suspected CAD were entered in an aggressive lifestyle modification program. Patients completed the Symptom Checklist 90-Revised (SCL90R) at the diagnostic interview session, at 3 and at 12 months. Statistically significant drops were observed on multiple scales of the SCL90R at both 3 and 12 months. An item from the SCL90R was used as a proxy for angina. Multiple measures of emotional distress at baseline were found to correlate with chest pain at baseline, but not a number of traditional cardiovascular risk factors. The chest pain item displayed improvement at both 3 and 12 months. Improvement on all scales of the SCL90R correlated with improvement in chest pain. It may be possible to control chest pain in some CAD patients with psychosocial interventions.
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PMID:Chest pain and the treatment of psychosocial/emotional distress in CAD patients. 1103 56

Systematic evaluation of end-of-life care in dementia has been hampered by a lack of instruments to specifically address those issues that are unique for persons who are dying with dementia. This study evaluated psychometric properties of three scales designed to measure outcomes of care of persons suffering from terminal dementia. A survey of family caregivers whose loved one died during the past year was conducted using a questionnaire that included questions regarding satisfaction with care, physical and emotional symptoms that occurred during the last 90 days of the care recipient's life, and comfort during the dying process. Three scales were developed based on responses from 156 questionnaires: Satisfaction with Care at the End-of-Life in Dementia (SWC-EOLD), Symptom Management at the End-of-Life in Dementia (SM-EOLD) with Physical and Psychological Symptoms subscales, and Comfort Assessment in Dying with Dementia (CAD-EOLD) with four subscales: Physical Distress, Dying Symptoms, Emotional Distress, and Well Being. The three scales developed and evaluated in this study can be used as outcome measures in studies investigating effectiveness of interventions aimed to improve end-of-life care for individuals with dementia.
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PMID:Scales for evaluation of End-of-Life Care in Dementia. 1172 70