Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.1.49 (
phosphoenolpyruvate carboxykinase
)
4,654
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase
2817
phosphoenolpyruvate carboxylase
1344
insulin
1043
PEPCK
570
glucose-6-phosphatase
505
pyruvate kinase
357
Mol
352
Sep
329
pyruvate carboxylase
279
ATP
274
glucagon
259
CO2
246
malate dehydrogenase
221
glucokinase
207
phosphatase
147
AMP
145
G6Pase
130
NADP
121
PEP
110
NAD
110
lactate dehydrogenase
108
fructose-1,6-bisphosphatase
103
NADH
103
ADP
103
GTP
98
glucocorticoid receptor
93
phosphofructokinase
91
NADP-malic enzyme
91
fatty acid synthase
89
peroxisome proliferator-activated receptor
89
glucose transporter
88
hexokinase
87
aspartate aminotransferase
86
Bot
86
PCK1
86
insulin receptor
81
glutamate dehydrogenase
80
leptin
80
IRS-1
77
glutamine synthetase
77
citrate synthase
73
NADPH
73
glycogen synthase
67
glucose-6-phosphate dehydrogenase
66
rhabdomyosarcoma
63
AMP-activated protein kinase
62
growth hormone
62
PEPCK-C
60
isocitrate dehydrogenase
58
alanine aminotransferase
57
AMPK
56
polypeptide
56
PGC
55
pyruvate dehydrogenase
55
TCA
54
NMR
54
TAT
52
albumin
52
protein kinase B
51
acetyl-CoA carboxylase
50
AKT
50
carbonic anhydrase
49
glycogen phosphorylase
49
peroxisome proliferator-activated receptor gamma
49
catalase
49
NAD-malic enzyme
47
proximal tubule
46
fructose 1,6-bisphosphatase
46
GDP
43
superoxide dismutase
43
EBP
40
CREB
40
ATPase
40
TNF
39
fused
39
epididymal
38
lipoprotein lipase
38
fumarase
34
nuclear receptor
34
glutaminase
34
more...
Disease
diabetes
350
hyperglycemia
216
type 2 diabetes
216
hepatocellular carcinoma
193
obesity
153
hypoglycemia
94
glucose intolerance
78
hyperinsulinemia
65
fatty liver
52
cancer
49
tumor
47
metabolic syndrome
41
CAM
34
FAS
31
cold
28
SDS
28
dyslipidemia
28
idiopathic thrombocytopenic purpura
25
hyperlipidemia
21
mole
19
mole
19
hypertension
17
depression
17
Mycobacterium
14
dehydration
12
sepsis
12
Benson
12
GSH
12
sepsis
12
ischemia
11
type 1 diabetes
11
Adenovirus
11
iron deficiency
10
pheochromocytoma
10
hyperphagia
10
tuberculosis
10
PCC
9
Schistosoma mansoni
9
metabolic disorder
9
worms
8
tapeworm
8
Evans
8
ketosis
8
liver cancer
8
schistosomiasis
7
Brown
7
renal disease
7
lactic acidosis
7
Hymenolepis
7
chlorosis
7
vitamin A deficiency
7
herpes simplex
7
tumor growth
7
lipodystrophy
7
infectious diseases
6
Echinococcus
6
tumorigenesis
6
carcinogenesis
6
liver cancer
6
malnutrition
6
leukemia
6
sudden infant death syndrome
6
liver disease
6
cardiovascular disease
6
West
5
AIN
5
endotoxic shock
5
chronic renal failure
5
malaria
5
pertussis
5
wasting syndrome
5
Chagas
5
alcoholic fatty liver
5
atherosclerosis
5
virus infection
5
neuroblastoma
5
gestational diabetes mellitus
4
renal tubular acidosis
4
stroke
4
cytomegalovirus
4
more...
Symptom
starvation
122
acidity
31
exhaustion
10
cachexia
7
fatigue
6
acute stress
6
hepatomegaly
6
anorexia
4
anesthesia
4
polyuria
3
splenomegaly
3
polydipsia
2
overweight
2
pain
2
thinning
2
Decreased activity
1
stigma
1
cough
1
discomfort
1
blackout
1
sleepiness
1
discomfort
1
loss of equilibrium
1
Anoxia
1
hypothermia
1
Tissue anoxia
1
tense
1
dizziness
1
emaciation
1
diarrhea
1
hunger
1
vomiting
1
hyperoxia
1
inanition
1
tremor
1
Drug
NADH
102
lysine
62
Glucagon
42
citric acid
39
CAM
33
Leaf
27
Gel
21
Fructose
19
ROS
17
DNase I
16
Glycerol
12
Asn
11
lactose
11
ascorbate
10
Rosiglitazone
10
Ethanol
9
MAP
9
NH3
8
Growth hormone
7
Alanine
7
Growth hormone
7
Diurnal
5
Aloe
5
Vitamin A
5
Forskolin
4
Troglitazone
4
Kenyan
4
caffeine
4
DMI
4
PCB
3
TAT
3
CoCl2
3
CoCl2
3
CDP
3
Capsicum
3
Scopolamine
3
Bifidobacterium
3
Albumin
2
Arsenic trioxide
2
Mutagen
2
Glycyrrhiza
2
ABC
2
G418
2
Myricetin
2
DEX
2
PTH
2
Retinoic acid
2
Fraction
2
Liraglutide
2
Posilac
2
Monit
2
Monensin
2
Vanilla
2
Portal
2
1-Deoxynojirimycin
2
THF
2
Vitamin B
2
RFP
1
Acyclovir
1
Citrus unshiu peel
1
Phenylphosphate
1
Ranitidine
1
Emodin
1
Riboflavin
1
Aspartic Acid
1
Aminoguanidine
1
Pentostam
1
Ginseng
1
Itraconazole
1
Colombo
1
Glutathione
1
Trilostane
1
CER
1
Salicylate
1
Rasburicase
1
Indomethacin
1
PFA
1
IL-2
1
Asthma
1
TEL
1
more...
Enzyme
phosphoenolpyruvate carboxykinase
4654
phosphoenolpyruvate carboxykinase
4186
phosphoenolpyruvate carboxykinase
4143
phosphoenolpyruvate carboxylase
1393
glucose-6-phosphatase
507
pyruvate kinase
361
pyruvate carboxylase
296
malate dehydrogenase
242
glucokinase
210
protein kinase
192
lactate dehydrogenase
112
AMP-activated protein kinase
109
phosphofructokinase
107
rubisco
98
aspartate aminotransferase
98
fructose 1,6-bisphosphatase
96
glucose-6-phosphate dehydrogenase
89
hexokinase
87
isocitrate dehydrogenase
83
alanine aminotransferase
83
glutamate dehydrogenase
80
glutamate dehydrogenase
80
glutamate dehydrogenase
80
glutamine synthetase
77
citrate synthase
76
pyruvate dehydrogenase
72
AMPK
69
phosphorylase
63
catalase
59
isocitrate dehydrogenase
58
isocitrate lyase
56
AMPK
56
PPDK
55
pyruvate dehydrogenase
54
pyruvate dehydrogenase
54
tyrosine aminotransferase
53
superoxide dismutase
52
acetyl-CoA carboxylase
52
mitogen-activated protein kinase
51
carbonic anhydrase
50
ATPase
47
glyceraldehyde-3-phosphate dehydrogenase
45
fumarase
42
glyceraldehyde-3-phosphate dehydrogenase
42
luciferase
40
CPT
40
succinate dehydrogenase
38
glutaminase
38
lipoprotein lipase
38
chloramphenicol acetyltransferase
37
glyceraldehyde-3-phosphate dehydrogenase
36
glyceraldehyde-3-phosphate dehydrogenase
35
glyceraldehyde-3-phosphate dehydrogenase
33
nitrate reductase
33
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
protein kinase C
31
oxaloacetate decarboxylase
30
glycerol kinase
28
phosphoglycerate kinase
28
phosphatidylinositol 3-kinase
27
aldolase
27
alcohol dehydrogenase
26
succinic dehydrogenase
25
glutamate synthase
25
aconitase
24
glutamate synthase
24
fumarate reductase
23
enolase
23
glutamate synthase
23
acetate kinase
22
calcineurin
22
focal adhesion kinase
22
malate synthase
22
alpha-ketoglutarate dehydrogenase
22
alkaline phosphatase
21
RNA polymerase
21
more...
Compound
glucose
1781
phosphate
386
Dec
344
CO2
300
ATP
274
DNA
269
cAMP
242
water
213
glycerol
186
oxygen
180
alanine
173
nitrogen
164
glutamate
162
AMP
153
PEP
148
acetate
146
Insulin
142
NADP
137
NAD
132
glutamine
131
NAD
110
ADP
110
serine
108
ADP
103
ADP
103
NADH
102
GTP
99
sodium
91
manganese
87
ammonium
85
ammonia
80
pentose
80
pentose
80
pentose
80
pentose
80
lysine
79
calcium
77
urea
76
acetyl-CoA
75
2-oxoglutarate
74
NADPH
73
NADPH
73
oxalacetate
73
ethanol
72
salt
70
Clin
70
glucose-6-phosphate
69
CoA
62
malic acid
61
TCA
59
Mg2+
56
nitrate
55
arginine
54
sulfate
48
tyrosine
47
Asp
46
hydrogen
45
proline
44
cysteine
44
GDP
44
HCO
43
nicotinamide
43
Glucagon
42
threonine
42
STZ
42
succinic acid
40
TNF
39
carbonate
38
galactose
38
tryptophan
36
hexose
35
hexose
34
tryptophan
34
retinoic acid
34
hexose
34
tryptophan
34
hexose
34
tryptophan
34
CAM
34
leucine
33
more...