Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.49 (phosphoenolpyruvate carboxykinase)
4,654 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase 2817
phosphoenolpyruvate carboxylase 1344
insulin 1043
PEPCK 570
glucose-6-phosphatase 505
pyruvate kinase 357
Mol 352
Sep 329
pyruvate carboxylase 279
ATP 274
glucagon 259
CO2 246
malate dehydrogenase 221
glucokinase 207
phosphatase 147
AMP 145
G6Pase 130
NADP 121
NAD 110
PEP 110
lactate dehydrogenase 108
ADP 103
NADH 103
fructose-1,6-bisphosphatase 103
GTP 98
glucocorticoid receptor 93
NADP-malic enzyme 91
phosphofructokinase 91
peroxisome proliferator-activated receptor 89
fatty acid synthase 89
glucose transporter 88
hexokinase 87
aspartate aminotransferase 86
Bot 86
PCK1 86
insulin receptor 81
leptin 80
glutamate dehydrogenase 80
IRS-1 77
glutamine synthetase 77
more...
Disease
diabetes 350
hyperglycemia 216
type 2 diabetes 216
hepatocellular carcinoma 193
obesity 153
hypoglycemia 94
glucose intolerance 78
hyperinsulinemia 65
fatty liver 52
cancer 49
tumor 47
metabolic syndrome 41
CAM 34
FAS 31
cold 28
dyslipidemia 28
SDS 28
idiopathic thrombocytopenic purpura 25
hyperlipidemia 21
mole 19
mole 19
hypertension 17
depression 17
Mycobacterium 14
GSH 12
sepsis 12
Benson 12
sepsis 12
dehydration 12
Adenovirus 11
ischemia 11
type 1 diabetes 11
pheochromocytoma 10
tuberculosis 10
iron deficiency 10
hyperphagia 10
metabolic disorder 9
Schistosoma mansoni 9
PCC 9
worms 8
more...
Symptom
starvation 122
acidity 31
exhaustion 10
cachexia 7
fatigue 6
acute stress 6
hepatomegaly 6
anorexia 4
anesthesia 4
polyuria 3
splenomegaly 3
polydipsia 2
overweight 2
pain 2
thinning 2
Decreased activity 1
stigma 1
cough 1
discomfort 1
blackout 1
sleepiness 1
discomfort 1
loss of equilibrium 1
Anoxia 1
hypothermia 1
Tissue anoxia 1
tense 1
dizziness 1
emaciation 1
diarrhea 1
hunger 1
vomiting 1
hyperoxia 1
inanition 1
tremor 1
Drug
NADH 102
lysine 62
Glucagon 42
citric acid 39
CAM 33
Leaf 27
Gel 21
Fructose 19
ROS 17
DNase I 16
Glycerol 12
Asn 11
lactose 11
ascorbate 10
Rosiglitazone 10
MAP 9
Ethanol 9
NH3 8
Growth hormone 7
Alanine 7
Growth hormone 7
Aloe 5
Diurnal 5
Vitamin A 5
caffeine 4
Forskolin 4
DMI 4
Troglitazone 4
Kenyan 4
CoCl2 3
CoCl2 3
TAT 3
Bifidobacterium 3
PCB 3
CDP 3
Capsicum 3
Scopolamine 3
Albumin 2
Arsenic trioxide 2
G418 2
more...
Enzyme
phosphoenolpyruvate carboxykinase 4654
phosphoenolpyruvate carboxykinase 4186
phosphoenolpyruvate carboxykinase 4143
phosphoenolpyruvate carboxylase 1393
glucose-6-phosphatase 507
pyruvate kinase 361
pyruvate carboxylase 296
malate dehydrogenase 242
glucokinase 210
protein kinase 192
lactate dehydrogenase 112
AMP-activated protein kinase 109
phosphofructokinase 107
rubisco 98
aspartate aminotransferase 98
fructose 1,6-bisphosphatase 96
glucose-6-phosphate dehydrogenase 89
hexokinase 87
isocitrate dehydrogenase 83
alanine aminotransferase 83
glutamate dehydrogenase 80
glutamate dehydrogenase 80
glutamate dehydrogenase 80
glutamine synthetase 77
citrate synthase 76
pyruvate dehydrogenase 72
AMPK 69
phosphorylase 63
catalase 59
isocitrate dehydrogenase 58
AMPK 56
isocitrate lyase 56
PPDK 55
pyruvate dehydrogenase 54
pyruvate dehydrogenase 54
tyrosine aminotransferase 53
acetyl-CoA carboxylase 52
superoxide dismutase 52
mitogen-activated protein kinase 51
carbonic anhydrase 50
more...
Compound
glucose 1781
phosphate 386
Dec 344
CO2 300
ATP 274
DNA 269
cAMP 242
water 213
glycerol 186
oxygen 180
alanine 173
nitrogen 164
glutamate 162
AMP 153
PEP 148
acetate 146
Insulin 142
NADP 137
NAD 132
glutamine 131
NAD 110
ADP 110
serine 108
ADP 103
ADP 103
NADH 102
GTP 99
sodium 91
manganese 87
ammonium 85
ammonia 80
pentose 80
pentose 80
pentose 80
pentose 80
lysine 79
calcium 77
urea 76
acetyl-CoA 75
2-oxoglutarate 74
more...