Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.49 (phosphoenolpyruvate carboxykinase)
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Human Gene/Protein
Hepatic nuclear factor 4 alpha 12.7
PEPCK 12.7
phosphoenolpyruvate carboxykinase 12.7
phosphoenolpyruvate carboxylase 12.6
PEPCK-M 12.3
PEPCK-C 12.0
zinc finger homeodomain protein 11.7
PCK1 11.6
PCK2 11.5
NADP-malic enzyme 11.4
HIST1H2BM 11.2
TCDD-inducible poly(ADP-ribose) polymerase 11.2
RNA-binding protein 6 11.2
NAD-malic enzyme 11.1
NAD-ME 11.1
NADP-ME 10.8
AREBP 10.7
pyruvate carboxylase, mitochondrial 10.7
cartilage intermediate layer protein 2 10.7
MRP-S9 10.7
G6Pase 10.7
TSE1 10.5
cytochrome c-1 10.4
pyruvate carboxylase 10.4
GAPT 10.2
Glutamic dehydrogenase 10.2
CAMKK 10.2
CPS1 protein 10.2
glucose-6-phosphatase 10.1
carboxylating 10.1
fructose-bisphosphatase 10.1
dihydrolipoamide S-succinyltransferase 9.9
GK5 9.9
APC2 protein 9.9
pck2 9.8
fructose 1,6-bisphosphatase 9.8
PDE3B protein 9.7
Forkhead/winged helix transcription factor 9.7
phosphoenolpyruvate carboxykinase 2 9.7
Tissue-specific extinguisher 1 9.6
Fructose-bisphosphate aldolase 9.6
SVOPL 9.6
glycerokinase 9.6
PLD5 9.6
NADP-dependent malic enzyme 9.5
fructose-1,6-bisphosphatase 9.5
pyruvate kinase L 9.5
CRTC2 9.4
Fructose 1,6-bisphosphatase 9.4
Pyruvate carboxylase 9.4
Malic enzyme 9.3
phosphorylase, glycogen 9.3
1-acylglycerol-3-phosphate O-acyltransferase 2 9.3
TCF7L2 protein 9.3
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase 9.2
TMED2 9.2
RFWD2 9.2
ZHX3 9.2
carbamoylphosphate synthetase I 9.2
ZFP91 9.2
liver glycogen synthase 9.1
TRB1 9.0
ME5 9.0
S171 9.0
AdPLA 9.0
FBPase 9.0
FBP1 9.0
IDP 9.0
fructose-1,6-bisphosphatase 1 9.0
glucokinase 8.9
constitutive heat shock protein 70 8.9
succinate dehydrogenase flavoprotein subunit 8.9
endosomal adaptor protein 8.9
ESA1 8.9
pyruvate kinase 8.9
BHLHE40 8.9
serine dehydratase 8.8
glycine dehydrogenase 8.8
FEEL-1 8.8
CAT5 8.8
Glucose-6-phosphatase 8.8
decarboxylating 8.8
phosphate-activated glutaminase 8.8
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 8.7
G6PT 8.7
GSD1a 8.7
malate dehydrogenase 8.7
Malate dehydrogenase 8.7
APOC4 8.7
PFK-2/FBPase-2 8.7
DOC1 8.7
MDH2 8.6
SLC27A2 8.6
RGPR-p117 8.6
tubulin beta chain 8.6
D-fructose-1,6-bisphosphate 1-phosphohydrolase 8.6
PDIP38 8.5
SLC38A3 8.5
CIDEB 8.5
DDF1 8.5
ATP-binding cassette transporter-1 8.5
protein-serine/threonine kinase 8.5
PEP 8.5
NADH dehydrogenase subunit 1 8.4
asialoglycoprotein receptor 1 8.4
6-phosphofructokinase 8.4
CL-6 8.3
very long-chain acyl-CoA synthetase 8.3
KCNJ15 8.3
MAEA 8.3
insulin-like peptide 5 8.3
SWP1 8.3
ARRDC3 8.3
fumarase 8.3
Par14 8.2
Phosphoserine phosphatase 8.2
DGKE 8.2
insulin receptor substrate-2 8.2
p102 8.2
GYS1 8.2
DGK-theta 8.2
cyclin I 8.2
phosphoglyceromutase 8.2
NFI-A 8.2
SLA1 8.1
PHT2 8.1
glucose-6-phosphate 1-dehydrogenase 8.1
HIG1 8.1
L-alpha-glycerophosphate dehydrogenase 8.1
carnitine palmitoyltransferase 1A 8.1
EHHADH 8.0
BDH2 8.0
Cytochrome c oxidase subunit I 8.0
CMP kinase 8.0
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 8.0
MT1M 8.0
CTLH 8.0
TORC2 8.0
carbamoylphosphate synthetase 7.9
aldolase B 7.9
OATP4C1 7.9
cAMP responsive element binding protein 1 7.9
SRCAP 7.9
hydroxypyruvate reductase 7.9
6-phosphofructo-2-kinase 7.9
SLC37A4 7.9
GART 7.9
Spot14 7.9
phosphofructokinase 1 7.9
HMGCS2 7.9
GLUT2 7.9
glycine decarboxylase 7.8
CPT1 7.8
DFF35 7.8
aquaporin 9 7.8
CRBP-II 7.8
5-methyltetrahydrofolate-homocysteine methyltransferase 7.8
hydroxymethylglutaryl-CoA synthase 7.8
Glucokinase 7.8
PKL 7.8
sterol regulatory element-binding protein-1c 7.8
AIRS 7.7
serine/threonine kinase 2 7.7
HSD-1 7.7
liver glycogen phosphorylase 7.7
argininosuccinate synthetase 7.7
NADH dehydrogenase subunit 5 7.7
SRC2 7.7
Inositol polyphosphate multikinase 7.7
Phosphoglycerate dehydrogenase 7.7
flotillin 2 7.7
CACT 7.6
G6PC3 7.6
PPP1R3B 7.6
protein serine kinase 7.6
TRB3 7.6
CCAAT-binding transcription factor 7.6
Kir4.2 7.6
SREBP-1a 7.6
ceruloplasmin mRNA 7.6
Protein-tyrosine phosphatase 1B 7.6
glycerate kinase 7.6
IKK epsilon 7.6
PGC-1 7.5
COX4I2 7.5
ALDOB 7.5
CYP46 7.5
PSPH 7.5
pyruvate dehydrogenase kinase 4 7.5
glycerol kinase 7.5
IRS2 7.5
phosphofructokinase 7.5
C/EBP alpha 7.5
glycogen synthase 7.5
Phosphoglycerate kinase 7.5
YWHAB 7.5
GCN5L1 7.5
hepatocyte nuclear factor 1 alpha 7.5
thyroid hormone receptor-associated protein 7.5
propionyl-CoA carboxylase 7.5
carnitine palmitoyltransferase 1 7.5
NIN1 7.5
PPARGC1B 7.5
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 7.5
aconitate hydratase 7.4
Pyruvate kinase 7.4
forkhead transcription factor 7.4
SOAT2 7.4
LZIP 7.4
ACO 7.4
pyridoxine 5'-phosphate oxidase 7.3
CAMKK2 7.3
midline 1 7.3
RCN1 7.3
Ornithine aminotransferase 7.3
ribophorin II 7.3
GLUT-2 7.3
acetyl-CoA synthetase 7.3
glucose transporter 4 7.3
PDK4 7.3
GLUD2 7.3
SREBP-1c 7.3
glycogen phosphorylase 7.3
glucose-6-phosphate transporter 7.3
LRP130 7.3
fatty-acid synthase 7.3
HMGCS1 7.3
DAP5 7.3
ACSA 7.3
SHP 7.3
Tyrosine aminotransferase 7.3
AF1 7.3
fatty acid synthase 7.3
COX4 7.2
AQP3 protein 7.2
ATP synthase subunit beta 7.2
RAR-related orphan receptor gamma 7.2
beta-fibrinogen 7.2
phenylalanine 4-monooxygenase 7.2
GALNT2 7.2
Cps1 7.2
Glycolate oxidase 7.2
ACADVL 7.2
LCAD 7.2
SLC2A2 7.2
alcohol dehydrogenase 1 7.2
SSB1 7.2
NR1D1 7.2
mitochondrial malate dehydrogenase 7.1
adropin 7.1
NF-I 7.1
sodium-potassium ATPase 7.1
NADP-dependent isocitrate dehydrogenase 7.1
ATP citrate lyase 7.1
isocitrate dehydrogenase 7.1
C/EBP beta 7.1
PSAT1 7.1
ASNS 7.1
CREBH 7.1
telomeric repeat binding factor 1 7.0
carnitine palmitoyltransferase 7.0
HNF4alpha 7.0
ACACA 7.0
alpha-ketoglutarate dehydrogenase 7.0
G6PDH 7.0
NR1F1 7.0
IRS-2 7.0
PRIP 7.0
tryptophan oxygenase 7.0
glucagon receptor 7.0
Fructose-1,6-bisphosphatase 7.0
glutaminase 7.0
CD5L 7.0
acetyl-CoA carboxylase 7.0
sterol regulatory element-binding protein 7.0
fumarate hydratase 7.0
Max protein 7.0
Argininosuccinate synthetase 7.0
LPMC 7.0
glutamate dehydrogenase 7.0
ACC1 7.0
peroxiredoxin 4 6.9
nuclear respiratory factor 2 6.9
glucokinase regulatory protein 6.9
PFK2 6.9
PLC1 6.9
EPRS 6.9
SLC29A1 6.9
carbohydrate response element binding protein 6.9
NOX3 6.9
UPP 6.9
citrate synthase 6.9
HIPK3 6.9
MTTP 6.9
androgen-regulated protein 6.9
tryptophan 2,3-dioxygenase 6.9
NADP 6.8
HSD1 6.8
INGAP 6.8
PHGDH 6.8
IRS-1 6.8
hexokinase 6.8
Steroidogenic factor-1 6.8
glutamate dehydrogenase 1 6.8
PLA2G2A 6.8
transaldolase 6.8
KRC 6.8
Tribbles homolog 3 6.7
COUP-TFII 6.7
glutamine synthetase 6.7
INSIG1 6.7
Glycerol kinase 6.7
DNA polymerase delta 6.7
fructokinase 6.7
sirtuin 6 6.7
HNF1alpha 6.7
UDP-glucose pyrophosphorylase 6.7
SREBP-1 6.7
Tectonic 6.7
E2F8 6.7
more...
Disease
Glucagon resistance 10.7
Avian reticuloendotheliosis 10.4
ALAD deficiency 8.8
Brain mass 8.6
Fasting hypoglycemia 8.0
Biotin deficiency 7.8
Neonatal respiratory distress syndrome 7.7
CPS deficiency 7.5
Paxton 7.4
coenurosis 7.2
Hers 7.1
porcine stress syndrome 6.9
Benson 6.6
Mohr 6.6
PNP deficiency 6.5
disorders of amino acid metabolism 6.5
MODY1 6.3
MODY2 6.2
PDH deficiency 6.2
diphyllobothriasis 6.0
diabetic hyperglycemia 5.9
AD1 5.8
orotic aciduria 5.8
hepatic porphyria 5.8
FAS 5.7
hyperglycemia 5.6
MODY 5.6
Jejunum 5.6
postmaturity 5.5
glucose intolerance 5.5
lymphoblastoma 5.4
CAM 5.4
hyperinsulinemia 5.4
AD2 5.3
potassium deficiency 5.2
Hymenolepis 5.2
LCS 5.1
kidney hypertrophy 5.1
LCAT deficiency 5.0
KMS 5.0
Buchanan 5.0
hypoglycemia 4.9
vitamin B6 deficiency 4.9
prolonged pregnancy 4.9
Simpson-Golabi-Behmel syndrome 4.9
KMS 4.8
LIP 4.8
tapeworm 4.8
wasting syndrome 4.8
ketosis 4.8
Enzyme inhibition 4.7
type 2 diabetes 4.7
idiopathic thrombocytopenic purpura 4.7
fatty liver 4.7
overnutrition 4.7
ACS1 4.6
endotoxic shock 4.6
Adenovirus 4.6
PRS 4.6
PER 4.6
vitamin A deficiency 4.6
beriberi 4.6
RDP 4.5
Spraying 4.5
chlorosis 4.4
lipodystrophy 4.4
AIN 4.4
Copper deficiency 4.4
hepatic neoplasm 4.3
HEP 4.3
HTL 4.2
hepatocellular carcinoma 4.2
APOB 4.2
DIG 4.1
fascioliasis 4.1
nutritional disorder 4.1
AOA 4.1
thiamine deficiency 4.1
FDH 4.0
PND 4.0
magnesium deficiency 4.0
endocrine disorder 4.0
Chronic hepatitis C 3.9
MPE 3.9
Parry 3.9
clonorchiasis 3.9
taeniasis 3.9
dyslipidemia 3.8
renal tubular acidosis 3.8
Anisakis 3.8
yaws 3.7
mitochondrial encephalomyopathy 3.7
immune disorder 3.7
metabolic disorder 3.6
LDLR 3.6
ovarian dysfunction 3.6
metabolic alkalosis 3.6
SCD 3.6
metabolic syndrome 3.5
MLS 3.5
lactic acidosis 3.5
intestinal cancer 3.5
hyperphagia 3.5
juvenile periodontitis 3.5
tubular necrosis 3.5
GSD 3.4
renal ischemia 3.4
KNO 3.4
Korsakoff's syndrome 3.4
PDP 3.4
NSD 3.4
SPS 3.4
reticuloendotheliosis 3.4
gestational trophoblastic disease 3.4
PCC 3.4
sudden infant death syndrome 3.3
iron deficiency 3.3
GSD 3.3
alcoholic fatty liver 3.2
INS 3.2
porphyria 3.2
Leigh syndrome 3.2
lipoatrophy 3.2
BCH 3.2
lipidosis 3.2
hyperlipidemia 3.2
systemic candidiasis 3.1
multiple disorders 3.1
diabetes 3.1
Schistosoma mansoni 3.1
PDC 3.1
CLN3 3.1
obesity 3.1
PCT 3.1
seminal vesicles 3.0
NPH 3.0
Nonalcoholic fatty liver 3.0
porphyria cutanea tarda 3.0
SPS 3.0
metritis 3.0
PSP 2.9
ABS 2.9
neonatal jaundice 2.9
SCS 2.9
hyperosmolality 2.9
insulinoma 2.9
HTS 2.9
mole 2.9
HCA 2.9
adrenal hyperplasia 2.9
ABS 2.8
maple syrup urine disease 2.8
BSE 2.8
Robinson 2.8
DMS 2.8
PGA 2.7
LBD 2.7
PIC 2.7
PAL 2.6
adrenal insufficiency 2.6
mole 2.6
vitreous humor 2.6
pH increased 2.5
PPP 2.5
megacolon 2.5
LAP 2.5
schistosomiasis 2.4
glycogen storage disease 2.4
EPS 2.4
Esophageal squamous cell carcinoma 2.3
parasitic disease 2.3
Pituitary 2.3
chemical carcinogenesis 2.3
retinopathy of prematurity 2.3
Echinococcus 2.3
Fox 2.2
pheochromocytoma 2.2
African trypanosomiasis 2.2
Mitchell 2.2
EPS 2.2
gestational diabetes mellitus 2.2
petechiae 2.2
MICA 2.2
respiratory acidosis 2.2
renal cyst 2.2
Evans 2.2
Recruitment 2.1
Brucella abortus 2.1
Wells 2.1
Fanconi syndrome 2.1
congenital disorder 2.1
Pineal 2.1
SAD 2.0
embryonal carcinoma 2.0
PDB 2.0
hypovitaminosis 2.0
Chagas 2.0
anovulation 2.0
Brown 1.9
polycythemia 1.9
SDS 1.9
type 1 diabetes 1.9
liver cancer 1.8
NBS 1.8
liver cancer 1.8
polycystic ovary syndrome 1.8
immunopathology 1.8
dehydration 1.8
Spleen 1.8
prediabetes 1.8
Nelson 1.7
hyperandrogenism 1.7
Friedreich's ataxia 1.7
worms 1.7
Marek's disease 1.7
AMD 1.7
dysentery 1.6
biliary atresia 1.6
Q fever 1.6
ADH 1.6
Moore 1.6
alkalosis 1.6
paracoccidioidomycosis 1.6
cysticercosis 1.5
Sweet 1.5
social stress 1.4
HSP 1.4
PDE 1.4
HGF 1.4
hyperthyroidism 1.4
wasting 1.4
Schmidt 1.4
diabetic nephropathy 1.3
zoonosis 1.3
hepatoblastoma 1.3
diabetic ketoacidosis 1.3
abdominal obesity 1.3
rheumatism 1.3
carcinomatosis 1.2
HCC 1.2
Blocking 1.2
lymphocytic choriomeningitis 1.1
cholestasis 1.1
aldosteronism 1.1
tic 1.1
GSH 1.1
brucellosis 1.1
hyperhomocysteinemia 1.1
Delhi 1.1
cold 1.1
mammary tumor 1.1
smallpox 1.0
NAME 1.0
progressive supranuclear palsy 1.0
failure to thrive 1.0
lichen 1.0
Pancreas 1.0
Syndrome 1.0
tumor initiation 0.9
diabetic neuropathy 0.9
thyrotoxicosis 0.9
Pancreas 0.9
Marfan syndrome 0.9
SAR 0.9
Mycobacterium 0.9
hyperuricemia 0.9
pertussis 0.8
herpes simplex 0.8
hypothyroidism 0.8
Fanconi 0.8
choriocarcinoma 0.7
acromegaly 0.7
Cryptococcus neoformans 0.7
Kawasaki disease 0.7
peripheral vascular disease 0.7
leishmaniasis 0.7
immaturity 0.7
sepsis 0.6
Hippel 0.6
chronic renal failure 0.6
thymoma 0.5
polycystic kidney 0.5
Disorder 0.5
malnutrition 0.5
lymphopenia 0.5
brain atrophy 0.5
Mycoplasma 0.5
sepsis 0.5
neoplastic transformation 0.5
renal cancer 0.5
infestation 0.4
bacterial infection 0.4
peritonitis 0.4
liver disease 0.4
leprosy 0.4
gout 0.4
vagina 0.4
sleep disturbances 0.3
neuroblastoma 0.3
respiratory disease 0.3
arteriosclerosis 0.3
hydronephrosis 0.3
vitamin D deficiency 0.3
cerebral ischemia 0.3
mimicry 0.2
muscular dystrophy 0.2
sickle cell disease 0.2
renal impairment 0.1
iron overload 0.1
psychological stress 0.1
renal disease 0.1
chronic hepatitis 0.0
NOD 0.0
nephritis 0.0
atrial septal defect -0.0
prematurity -0.1
cytomegalovirus -0.1
glomerulosclerosis -0.1
ash -0.1
tuberculosis -0.2
more...
Symptom
Tissue anoxia 10.4
loss of equilibrium 5.6
starvation 5.1
inanition 4.9
blackout 3.9
acidity 3.8
Decreased activity 3.7
Anoxia 3.6
acute stress 3.2
cachexia 3.1
hepatomegaly 2.8
polyuria 2.7
emaciation 2.7
polydipsia 2.6
exhaustion 2.3
tense 1.7
splenomegaly 1.1
anorexia 1.0
hyperoxia 0.4
thinning 0.3
hunger 0.3
fatigue -0.3
dizziness -0.5
sleepiness -0.9
overweight -0.9
stigma -1.0
hypothermia -1.3
tremor -1.4
discomfort -1.7
cough -1.8
discomfort -1.8
anesthesia -2.0
vomiting -2.2
diarrhea -3.1
pain -4.3
Drug
Sulfopyruvate 10.4
Phenylphosphate 9.6
Cottonseed oil 8.9
p-Chlorophenyl 8.8
Citrus unshiu peel 8.7
Posilac 8.4
1-Deoxynojirimycin 8.1
Aspartic Acid 7.6
Sodium sulfate 7.5
Nipradilol 6.8
Vanilla 6.6
Pyridoxamine 6.6
Calan 6.5
Rosiglitazone 6.4
Glucagon 6.3
Fructose 6.1
Trilostane 6.0
Ipriflavone 5.8
Troglitazone 5.7
Myricetin 5.5
Pentostam 5.4
CAM 5.3
Carbenoxolone 5.2
Glycerol 5.1
NADH 5.0
Liraglutide 5.0
Ammonium chloride 4.9
Aloe 4.8
Rasburicase 4.8
citric acid 4.8
CDX 4.7
Asparaginase 4.7
Isoptin 4.7
CER 4.6
Exenatide 4.4
Gemfibrozil 4.4
Colombo 4.4
Flavin 4.3
Enrofloxacin 4.3
Diurnal 4.3
CDX 4.3
Alanine 4.1
CoCl2 4.0
CoCl2 4.0
Aminoguanidine 4.0
Growth hormone 4.0
Scopolamine 4.0
beta-Galactosidase 4.0
Growth hormone 4.0
DEX 3.9
Valsartan 3.9
Emodin 3.9
Monensin 3.8
Glutamic acid 3.7
Citric acid 3.7
DNase I 3.7
DMI 3.7
Orphan 3.7
Indocyanine green 3.6
Salicylate 3.6
Clofibrate 3.6
Emodin 3.6
Dasatinib 3.5
Vitamin A 3.5
Vitamin B 3.4
Arsenic trioxide 3.4
Forskolin 3.4
Gel 3.3
Glycyrrhiza 3.3
Carotenoid 3.2
OTC 3.2
Capsicum 3.2
Riboflavin 3.1
CDP 3.1
TEL 3.1
AGG 3.1
TAT 3.1
Leaf 3.1
Kenyan 3.0
NH3 3.0
Adenosine triphosphate 2.9
lysine 2.9
TAK 2.8
PFA 2.7
Acyclovir 2.7
OTC 2.7
Asn 2.7
Ethanol 2.7
IL-11 2.6
G418 2.6
ROS 2.6
RFP 2.5
Vitamin B12 2.5
Fraction 2.4
Honey 2.4
PCB 2.3
Prednisolone 2.2
lactose 2.2
balanced salt solution 2.2
Coral 2.1
Triclosan 2.1
Ranitidine 2.1
TAC 2.1
Ginseng 2.1
Retinoic acid 2.0
MAP 2.0
PTC 2.0
Bifidobacterium 1.8
Itraconazole 1.8
Portal 1.7
ascorbate 1.6
Albumin 1.5
pyridoxal phosphate 1.4
ALA 1.3
Mutagen 1.2
Heme 1.1
Atropine 1.1
PTH 1.0
MRC 1.0
niacin 0.9
THF 0.7
ABC 0.6
Glutathione 0.3
caffeine 0.3
FAD 0.3
Indomethacin 0.1
CaCl2 0.1
CaCl2 0.1
CaCl2 0.1
EPA -0.1
EE2 -0.2
Nephron -0.8
ampicillin -1.3
Monit -1.4
vitamin E -1.4
Nephron -1.4
Asthma -1.9
IL-2 -2.1
Dermatol -5.3
Enzyme
phosphoenolpyruvate carboxykinase 12.7
phosphoenolpyruvate carboxykinase 12.7
phosphoenolpyruvate carboxykinase 12.7
phosphoenolpyruvate carboxylase 12.5
EC 1.3.1.37 12.2
PEP phosphatase 12.1
L-idonate dehydrogenase 11.7
EC 4.1.1.40 11.7
PPDK 11.2
malyl-CoA lyase 10.4
CimA 10.4
pyruvate carboxylase 10.4
phosphoenolpyruvate synthase 10.3
oxaloacetate decarboxylase 10.3
glucose-6-phosphatase 10.1
fructose 1,6-bisphosphatase 9.7
EC 1.1.1.82 9.7
malate thiokinase 9.4
EC 1.1.1.38 9.3
nucleotide 3'-pyrophosphokinase 9.3
UGT85B1 9.3
triokinase 9.2
glycine dehydrogenase 9.0
glycine dehydrogenase 9.0
rubisco 9.0
glucokinase 9.0
aldose-6-phosphate reductase 8.9
pyruvate kinase 8.9
EC 1.1.1.40 8.9
citrate cleavage enzyme 8.7
glutaminase II 8.7
isocitrate lyase 8.6
sucrose-phosphatase 8.6
malate dehydrogenase 8.5
propionate kinase 8.4
glycine dehydrogenase 8.4
carbamoylphosphate synthetase 8.4
acetate kinase 8.3
EC 2.6.1.4 8.2
malate synthase 8.2
GapB 8.2
tyrosine aminotransferase 8.1
hydroxypyruvate reductase 8.1
pyruvate:ferredoxin oxidoreductase 8.1
glycerol kinase 8.0
pyruvate formate-lyase 8.0
fumarase 8.0
fumarate reductase 8.0
citrate lyase 7.9
hydroxypyruvate reductase 7.9
AIR synthetase 7.9
glycolate dehydrogenase 7.9
trehalose phosphate synthase 7.8
6-phosphofructo-2-kinase 7.8
glutamate synthase 7.8
glycine decarboxylase 7.8
glutamate synthase 7.7
SBPase 7.7
diaminopimelate dehydrogenase 7.7
glycerate kinase 7.7
citramalate synthase 7.7
propionyl-CoA carboxylase 7.6
ferric chelate reductase 7.6
acetyl-CoA synthetase 7.6
glutamate synthase 7.6
12-oxophytodienoate reductase 7.6
phosphofructokinase 7.6
carboxypeptidase S 7.6
transcarboxylase 7.5
diaminopimelate decarboxylase 7.5
dihydroxyacetone kinase 7.5
aspartokinase 7.4
NADPH:quinone oxidoreductase 7.4
glycerol 3-phosphate dehydrogenase 7.4
EC 1.1.1.39 7.4
isocitrate dehydrogenase 7.4
propionyl-CoA carboxylase 7.3
ornithine cyclodeaminase 7.3
argininosuccinate synthetase 7.3
desulfinase 7.2
ABA2 7.2
dihydrodipicolinate reductase 7.2
EC 1.7.7.1 7.1
glutaminase 7.1
AMP-activated kinase 7.0
fatty-acid synthase 7.0
sucrose synthase 7.0
methylglyoxal synthase 7.0
fructokinase 7.0
3-hydroxybutyryl-CoA dehydrogenase 7.0
isocitrate dehydrogenase 7.0
chlorophyllase 7.0
oxoglutarate dehydrogenase 7.0
nucleoside diphosphokinase 7.0
glutamate dehydrogenase 7.0
glutamate dehydrogenase 7.0
acetyl-CoA carboxylase 7.0
glutamate dehydrogenase 6.9
asparagine synthetase 6.9
allantoicase 6.9
L-serine dehydratase 6.9
phosphofructokinase 1 6.9
alpha-ketoglutarate dehydrogenase 6.9
citrate synthase 6.9
HMG-CoA synthase 6.8
EC 2.7.7.9 6.8
hexokinase 6.8
EC 1.1.1.47 6.7
phosphoglyceromutase 6.7
pyruvate dehydrogenase 6.7
pyruvate dehydrogenase 6.7
D-alanine:D-alanine ligase 6.7
glutamine synthetase 6.7
MDH 6.7
transaldolase 6.7
argininosuccinate lyase 6.6
10-formyltetrahydrofolate dehydrogenase 6.6
succinic dehydrogenase 6.6
Mg-chelatase 6.6
ADP-glucose pyrophosphorylase 6.6
transhydrogenase 6.6
dihydrolipoamide succinyltransferase 6.6
MDH 6.6
6-phosphogluconate dehydrogenase 6.6
6-phosphogluconate dehydrogenase 6.6
aconitase 6.5
glutamic dehydrogenase 6.5
11beta-hydroxysteroid dehydrogenase 6.5
threonine synthase 6.5
pyruvate dehydrogenase 6.5
biotin carboxylase 6.5
branched-chain aminotransferase 6.5
octopine dehydrogenase 6.5
phosphoglycerate kinase 6.5
glyoxylate reductase 6.5
tryptophan 2,3-dioxygenase 6.4
isoflavone reductase 6.4
glyoxylate reductase 6.4
CMP kinase 6.4
granule-bound starch synthase 6.4
dihydroxyacetone phosphate acyltransferase 6.4
succinyl-CoA synthetase 6.4
STK3 6.3
glycerophosphodiester phosphodiesterase 6.3
glucose-6-phosphate dehydrogenase 6.3
6-phosphogluconolactonase 6.3
acyl-CoA oxidase 6.3
pyruvate dehydrogenase phosphatase 6.3
phosphorylase 6.3
reductoisomerase 6.3
pyruvate oxidase 6.3
glycolate oxidase 6.3
pyruvate oxidase 6.2
ornithine transcarbamylase 6.2
CYP8B1 6.2
aromatic amino acid aminotransferase 6.2
beta-hydroxybutyrate dehydrogenase 6.2
phosphoglycolate phosphatase 6.2
3-oxoacid CoA-transferase 6.1
diacylglycerol acyltransferase 6.1
leucine dehydrogenase 6.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.1
monoacylglycerol acyltransferase 6.1
lysine decarboxylase 6.1
alpha-isopropylmalate synthase 6.1
phosphoribulokinase 6.0
sucrose phosphorylase 6.0
aspartase 6.0
adenylosuccinate synthetase 6.0
phosphatidate phosphatase 6.0
phosphoglycerate dehydrogenase 6.0
isoprene synthase 6.0
acetoacetyl-CoA thiolase 6.0
NAD+ oxidoreductase 6.0
arginine kinase 6.0
beta-amylase 5.9
AMPK 5.9
glycerol dehydrogenase 5.9
hormone-sensitive lipase 5.9
CPT 5.9
CPS 5.9
sterol carrier protein 5.9
nitrate reductase 5.9
nitrate reductase 5.9
SPS 5.9
nitrate reductase 5.9
nitrate reductase 5.9
glycerol dehydrogenase 5.9
nitrate reductase 5.9
nitrate reductase 5.9
glycerol-3-phosphate dehydrogenase 5.9
Escherichia coli exonuclease III 5.9
ATP sulfurylase 5.8
aminopeptidase I 5.8
AMP-activated protein kinase 5.8
transglucosylase 5.8
glycerol-3-phosphate dehydrogenase 5.8
pyruvate decarboxylase 5.8
phosphoglucose isomerase 5.8
CYP7A1 5.8
glutamate racemase 5.8
LPL 5.8
glyceraldehyde-3-phosphate dehydrogenase 5.8
glyceraldehyde-3-phosphate dehydrogenase 5.8
aldolase 5.7
NADH peroxidase 5.7
homoserine kinase 5.7
glyceraldehyde-3-phosphate dehydrogenase 5.7
threonine dehydrogenase 5.7
glyceraldehyde-3-phosphate dehydrogenase 5.7
phosphoserine phosphatase 5.7
chloramphenicol acetyltransferase 5.6
adenylate kinase 5.6
PDK1 5.6
endoproteinase Glu-C 5.6
formate dehydrogenase 5.6
formate dehydrogenase 5.6
7-dehydrocholesterol reductase 5.6
deoxyguanosine kinase 5.6
SCS 5.6
phosphoketolase 5.6
serine hydroxymethyltransferase 5.5
malonyl-CoA decarboxylase 5.5
glycinamide ribonucleotide transformylase 5.5
dihydrodipicolinate synthase 5.5
carbonic anhydrase 5.5
methylenetetrahydrofolate dehydrogenase 5.5
formate dehydrogenase 5.5
PTA 5.5
glyceraldehyde-3-phosphate dehydrogenase 5.5
glycerophosphate acyltransferase 5.4
lactase-phlorizin hydrolase 5.4
glycine N-methyltransferase 5.4
betaine-homocysteine methyltransferase 5.4
glycine amidinotransferase 5.4
enolase 5.4
acyl-CoA synthetase 5.4
NMT 5.4
3-hydroxyacyl-CoA dehydrogenase 5.3
3-hydroxyacyl-CoA dehydrogenase 5.3
phytochelatin synthase 5.3
dCMP deaminase 5.3
violaxanthin de-epoxidase 5.3
coproporphyrinogen III oxidase 5.3
phosphomannose isomerase 5.3
AMPK 5.2
fructose-2,6-bisphosphatase 5.2
TSR 5.2
proteinase A 5.2
dehydroascorbate reductase 5.2
lipoprotein lipase 5.2
nicotinamide phosphoribosyltransferase 5.2
CPT 5.2
triose-phosphate isomerase 5.2
adenylosuccinate lyase 5.2
phosphoglucomutase 5.1
branched-chain alpha-keto acid dehydrogenase 5.1
acyl-CoA dehydrogenase 5.1
methylmalonyl-CoA mutase 5.1
phenylalanine hydroxylase 5.1
PGM 5.1
dUTPase 5.1
acyl-CoA dehydrogenase 5.1
CPT 5.1
amylomaltase 5.0
lactase-phlorizin hydrolase 5.0
factor C 5.0
carnitine acetyltransferase 5.0
acyl-CoA synthetase 5.0
succinate dehydrogenase 5.0
alanyl-tRNA synthetase 5.0
pyridoxal kinase 5.0
TDH 5.0
lysophospholipase D 5.0
aspartate aminotransferase 5.0
cysteine dioxygenase 4.9
proton-translocating ATPase 4.9
inositol 3-kinase 4.9
histidase 4.9
SOR 4.8
formaldehyde dehydrogenase 4.8
ornithine aminotransferase 4.8
estrogen sulfotransferase 4.8
3-hydroxy-3-methylglutaryl coenzyme A reductase 4.8
TOR 4.8
pantothenate kinase 4.8
alcohol oxidase 4.8
coproporphyrinogen oxidase 4.7
fatty acid elongase 4.7
ascorbate peroxidase 4.7
lactate dehydrogenase 4.7
condensing enzyme 4.7
proteinase A 4.7
arginine decarboxylase 4.7
alanine dehydrogenase 4.7
3-hydroxy-3-methylglutaryl-CoA reductase 4.6
phenol oxidase 4.6
succinic semialdehyde dehydrogenase 4.5
uricase 4.5
NADH dehydrogenase 4.5
LIS 4.5
nitrite reductase 4.5
phosphoinositide 3-kinase 4.5
arginine decarboxylase 4.5
cysteine synthase 4.5
EPSP synthase 4.5
branching enzyme 4.4
nitrite reductase 4.4
protochlorophyllide oxidoreductase 4.4
nitrite reductase 4.4
acetolactate synthase 4.4
alanine aminotransferase 4.4
transketolase 4.4
spermidine synthase 4.4
callose synthase 4.4
orotidine-5'-phosphate decarboxylase 4.4
inositol phosphatase 4.4
orotate phosphoribosyltransferase 4.4
arginase 4.3
glutathione synthetase 4.3
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Compound
Perfluorosuccinate 12.7
Linderane 12.7
Ethyl bromopyruvate 12.7
Glyoxal bisulfite 12.7
Diethyl oxaloacetate 11.7
Potassium sulfate 10.4
Potassium sulfate 10.4
Gentianine 10.2
3-MPA 9.9
Hydrazine sulfate 9.8
o-Iodosobenzoate 9.7
3-sulfopyruvate 9.6
Phenylphosphate 9.6
Saponarin 9.6
N-formimino-l-glutamate 9.4
oxalacetate 9.4
Butylamine 9.0
Ribose 5-phosphate 8.9
IDP 8.9
PEP 8.8
Swertiamarin 8.7
GW 9662 8.6
Malate 8.6
Amarogentin 8.5
1-Anilinonaphthalene 8.3
Trehalose-6-phosphate 8.1
Aminoimidazole 7.9
Glucose 6-phosphate 7.9
6-phosphogluconolactone 7.9
dCDP 7.7
Syringaldehyde 7.6
malic acid 7.5
Ribulose 7.5
Pyruvate kinase 7.4
mercaptopyruvate 7.4
propionyl-coenzyme A 7.3
Ectoine 7.3
dGDP 7.3
Sodium sulfate 7.3
Diosmin 7.3
Bromelia 7.2
Nialamide 7.2
4-fluorophenylalanine 7.2
Quinolinic acid 7.1
Myricitrin 7.1
glucose-6-phosphate 7.1
Phenelzine 7.1
Phenelzine 7.0
Glyoxylate 7.0
6-fluorotryptophan 7.0
2,3-dimercapto-1-propanol 6.9
2,3-dimercapto-1-propanol 6.9
Beclomethasone 6.9
Pyruvate 6.9
Eupatilin 6.9
malic acid 6.9
malic acid 6.9
malic acid 6.9
Triamcinolone 6.8
2-phosphoglycerate 6.8
ADP-glucose 6.7
Azocoll 6.6
Glabridin 6.6
thieno[2,3-b]pyridine 6.6
CONV 6.6
Acetyl phosphate 6.6
acetyl-CoA 6.6
Dibutyryl cyclic AMP 6.6
2-Oxoglutarate 6.6
Dibutyryl cyclic AMP 6.6
Pyridoxamine 6.5
ITP 6.5
NPR 6.5
2-amino-2-methyl-1-propanol 6.5
pentose 6.5
pentose 6.5
Glycerate 6.5
2-decenoic acid 6.4
D-xylulose-5-phosphate 6.4
Succinyl-CoA 6.4
Phlorizin 6.4
pentose 6.4
NADP 6.4
AICAR 6.4
2-amino-2-methyl-1-propanol 6.4
D-glucose 1-phosphate 6.3
Metalaxyl 6.3
isocitrate 6.3
pentose 6.3
PGB1 6.3
Fumarate 6.3
succinic acid 6.3
Dihydroxyacetone 6.3
Glucagon 6.3
1-Methyl-4-phenylpyridinium 6.2
STZ 6.2
succinic acid 6.2
succinic acid 6.2
succinic acid 6.2
succinic acid 6.2
carbamyl phosphate 6.2
UPP 6.2
Tyrosol 6.2
EH2 6.1
2-oxoglutarate 6.1
6-phosphogluconate 6.1
Steviol 6.1
Amytal 6.1
Hesperidin 6.0
TCTP 6.0
Fructose 6.0
mannitol-1-phosphate 6.0
hexacosanoic acid 6.0
Chlorophyll 6.0
2-oxoadipate 6.0
Propionate 5.9
glutaryl-CoA 5.9
Bisphenol S 5.9
2,4-pentanedione 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
adenylosuccinate 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
Glycogen 5.8
HCO 5.8
G3P 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
Zeatin 5.8
2,4-pentanedione 5.8
Roxarsone 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.8
2,4-pentanedione 5.7
Bifenthrin 5.7
Catalpol 5.7
Dihydromyricetin 5.7
Delphinidin 5.6
Selenate 5.6
ATF 5.6
DXP 5.6
O-acetylserine 5.6
Benzothiazole 5.6
1,2-dichloroethylene 5.6
Glutamine 5.6
Flux 5.6
cyclohexanecarboxylic acid 5.5
cyclohexanecarboxylic acid 5.5
cyclohexanecarboxylic acid 5.5
cyclohexanecarboxylic acid 5.5
1,2-dichloroethylene 5.5
cyclohexanecarboxylic acid 5.5
AICAR 5.5
alloxan 5.5
Glycine, 5.5
TCA 5.5
Naringin 5.5
2-oxobutyrate 5.5
Malonate 5.5
Trovafloxacin 5.5
Geniposide 5.5
malonyl-CoA 5.4
IBP 5.4
IBP 5.4
O-acetylserine 5.4
acetylglutamate 5.4
Pinene 5.4
1,3-butanediol 5.3
PPi 5.3
Equol 5.3
glucose 5.3
Glycyrrhetinic acid 5.3
PNU 5.3
Chlorophyll a 5.3
1,2-cyclohexanedione 5.3
hexose 5.3
hexose 5.3
hexose 5.3
Zeaxanthin 5.3
DPS 5.3
Withaferin A 5.3
1,3-butanediol 5.2
NAD 5.2
Ginsenoside Rg1 5.2
Triiodothyronine 5.2
CPT 5.2
GAP 5.2
Hydrazine 5.2
Glycine, 5.2
MPA 5.1
MPA 5.1
Pinene 5.1
Anisomycin 5.1
FDP 5.1
Insulin 5.1
Dexamethasone 5.1
NAD 5.1
Parthenolide 5.1
diisobutyl phthalate 5.1
Pioglitazone 5.1
Ritonavir 5.1
CPT 5.1
2,4-pentanedione 5.1
glutamine 5.1
D-gluconate 5.1
ribose-5-phosphate 5.1
MPA 5.1
10-formyltetrahydrofolate 5.1
MAK 5.0
Biotin 5.0
Glycyrrhetinic acid 5.0
Shikimate 5.0
O-acetylserine 5.0
Morin 5.0
NADH 5.0
DDC 5.0
CIT 5.0
meso-diaminopimelate 5.0
TGR 5.0
Ethacrynic acid 5.0
Selenomethionine 5.0
DDC 5.0
glycerol 5.0
Lactate 5.0
Potassium chloride 4.9
Tryptamine 4.9
TCDD 4.9
fructose-6-P 4.9
Glycolate 4.9
Vanillin 4.9
Parthenolide 4.9
Naringin 4.8
cAMP 4.8
2-oxobutyrate 4.8
DIM 4.8
CoA 4.8
Tetrandrine 4.8
Tetrandrine 4.8
Tetrandrine 4.8
HBC 4.8
Tetrandrine 4.8
hexose 4.8
GDP 4.7
S 1 4.7
Sucrose 4.7
Ethacrynic acid 4.7
AMP 4.6
AF-2 4.6
dicarboxylic acid 4.6
3-hydroxybutyric acid 4.6
PCMB 4.6
PCMB 4.6
PCMB 4.6
LY 294002 4.6
Ferulic acid 4.6
Cypermethrin 4.6
Ferulic acid 4.5
Glycogen synthase 4.5
GTP 4.5
Paeoniflorin 4.5
Diazinon 4.5
PCMB 4.5
Cycloheximide 4.5
NaAsO2 4.5
CO2 4.5
Loperamide 4.5
CAM 4.5
Fenofibrate 4.5
Arsenite 4.5
Honokiol 4.5
glucosamine-6-phosphate 4.4
PCB 126 4.4
20-HETE 4.4
Cholic acid 4.4
alpha-terpineol 4.4
phthalaldehyde 4.4
Paraquat 4.3
Hypo 4.3
isophthalic acid 4.3
NADPH 4.3
alcohol dehydrogenase 4.3
NADPH 4.3
Glucosamine 4.3
Ochratoxin A 4.3
Ferredoxin 4.3
FFA 4.3
HEP 4.3
2-methoxyphenol 4.2
CdCl2 4.2
C6H6 4.2
1,4-butanediol 4.2
ADP 4.2
Paraquat 4.2
ADP 4.2
N-(4-hydroxyphenyl)retinamide 4.2
L-T3 4.2
C6H6 4.2
Triton WR-1339 4.2
Alanine 4.2
nicotinamide 4.2
Wortmannin 4.2
Carnitine 4.2
Ursolic acid 4.2
ADP 4.1
PAE 4.1
7-methylguanosine 4.1
PTU 4.1
manganese 4.1
AIR 4.1
alanine 4.1
Formate 4.1
adenylate 4.0
Genistein 4.0
Serine 4.0
Glutamate 4.0
aspartic acid 4.0
more...