Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.1.49 (
phosphoenolpyruvate carboxykinase
)
4,654
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase
2817
phosphoenolpyruvate carboxylase
1344
insulin
1043
PEPCK
570
glucose-6-phosphatase
505
pyruvate kinase
357
Mol
352
Sep
329
pyruvate carboxylase
279
ATP
274
glucagon
259
CO2
246
malate dehydrogenase
221
glucokinase
207
phosphatase
147
AMP
145
G6Pase
130
NADP
121
NAD
110
PEP
110
more...
Disease
diabetes
350
type 2 diabetes
216
hyperglycemia
216
hepatocellular carcinoma
193
obesity
153
hypoglycemia
94
glucose intolerance
78
hyperinsulinemia
65
fatty liver
52
cancer
49
tumor
47
metabolic syndrome
41
CAM
34
FAS
31
cold
28
dyslipidemia
28
SDS
28
idiopathic thrombocytopenic purpura
25
hyperlipidemia
21
mole
19
more...
Symptom
starvation
122
acidity
31
exhaustion
10
cachexia
7
fatigue
6
hepatomegaly
6
acute stress
6
anorexia
4
anesthesia
4
splenomegaly
3
polyuria
3
polydipsia
2
overweight
2
thinning
2
pain
2
diarrhea
1
Decreased activity
1
cough
1
discomfort
1
blackout
1
more...
Drug
NADH
102
lysine
62
Glucagon
42
citric acid
39
CAM
33
Leaf
27
Gel
21
Fructose
19
ROS
17
DNase I
16
Glycerol
12
lactose
11
Asn
11
Rosiglitazone
10
ascorbate
10
Ethanol
9
MAP
9
NH3
8
Growth hormone
7
Growth hormone
7
more...
Enzyme
phosphoenolpyruvate carboxykinase
4654
phosphoenolpyruvate carboxykinase
4186
phosphoenolpyruvate carboxykinase
4143
phosphoenolpyruvate carboxylase
1393
glucose-6-phosphatase
507
pyruvate kinase
361
pyruvate carboxylase
296
malate dehydrogenase
242
glucokinase
210
protein kinase
192
lactate dehydrogenase
112
AMP-activated protein kinase
109
phosphofructokinase
107
rubisco
98
aspartate aminotransferase
98
fructose 1,6-bisphosphatase
96
glucose-6-phosphate dehydrogenase
89
hexokinase
87
alanine aminotransferase
83
isocitrate dehydrogenase
83
more...
Compound
glucose
1781
phosphate
386
Dec
344
CO2
300
ATP
274
DNA
269
cAMP
242
water
213
glycerol
186
oxygen
180
alanine
173
nitrogen
164
glutamate
162
AMP
153
PEP
148
acetate
146
Insulin
142
NADP
137
NAD
132
glutamine
131
more...