Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.1.32 (
phosphoenolpyruvate carboxykinase
)
4,204
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase
2811
phosphoenolpyruvate carboxylase
1280
insulin
863
glucose-6-phosphatase
481
pyruvate kinase
332
Mol
309
Sep
301
pyruvate carboxylase
279
glucagon
239
CO2
231
ATP
225
malate dehydrogenase
215
glucokinase
188
PEPCK
168
phosphatase
150
AMP
143
NADP
123
NAD
106
lactate dehydrogenase
106
fructose-1,6-bisphosphatase
98
PEP
97
NADH
96
NADP-malic enzyme
90
aspartate aminotransferase
89
Bot
86
phosphofructokinase
84
hexokinase
83
glucocorticoid receptor
83
fatty acid synthase
82
glucose transporter
81
PCK1
81
peroxisome proliferator-activated receptor
80
glutamate dehydrogenase
79
ADP
79
GTP
78
glutamine synthetase
75
citrate synthase
72
NADPH
67
insulin receptor
65
PEPCK-C
65
glucose-6-phosphate dehydrogenase
63
glycogen synthase
62
alanine aminotransferase
59
leptin
59
isocitrate dehydrogenase
57
growth hormone
56
IRS-1
54
pyruvate dehydrogenase
52
NMR
51
AMP-activated protein kinase
51
G6Pase
50
TAT
50
polypeptide
49
acetyl-CoA carboxylase
48
albumin
48
TCA
48
glycogen phosphorylase
47
protein kinase B
47
carbonic anhydrase
47
fructose 1,6-bisphosphatase
46
catalase
46
NAD-malic enzyme
45
superoxide dismutase
43
peroxisome proliferator-activated receptor gamma
41
rhabdomyosarcoma
41
EBP
39
proximal tubule
39
PGC
39
fused
38
ATPase
38
lipoprotein lipase
37
glutaminase
33
Pyruvate carboxylase
32
glyceraldehyde-3-phosphate dehydrogenase
32
GDP
32
CAM
32
carboxylating
30
reductase
30
AKT
30
fumarase
29
more...
Disease
diabetes
265
hyperglycemia
176
hepatocellular carcinoma
174
type 2 diabetes
163
obesity
110
hypoglycemia
81
glucose intolerance
61
hyperinsulinemia
53
tumor
46
cancer
44
fatty liver
43
CAM
33
metabolic syndrome
29
cold
26
SDS
24
idiopathic thrombocytopenic purpura
21
dyslipidemia
20
mole
18
mole
18
depression
18
hypertension
15
hyperlipidemia
14
Mycobacterium
14
Benson
12
dehydration
11
sepsis
11
tuberculosis
11
sepsis
11
pheochromocytoma
10
GSH
10
hyperphagia
10
iron deficiency
10
PCC
9
Schistosoma mansoni
9
Adenovirus
9
ketosis
9
type 1 diabetes
8
chlorosis
8
tapeworm
7
metabolic disorder
7
Evans
7
lipodystrophy
7
FAS
7
herpes simplex
7
schistosomiasis
7
tumor growth
7
lactic acidosis
6
Echinococcus
6
sudden infant death syndrome
6
worms
6
ischemia
6
malnutrition
6
vitamin A deficiency
6
leukemia
6
cardiovascular disease
6
AIN
5
virus infection
5
pertussis
5
endotoxic shock
5
Brown
5
West
5
malaria
5
liver cancer
5
wasting syndrome
5
tumorigenesis
5
infectious diseases
5
liver disease
5
carcinogenesis
5
renal disease
5
renal tubular acidosis
4
Mohr
4
seminal vesicles
4
cytomegalovirus
4
chronic renal failure
4
overnutrition
4
PDB
4
HIV
4
Hymenolepis
4
alcoholic fatty liver
4
hyperthyroidism
4
more...
Symptom
starvation
116
acidity
30
exhaustion
9
cachexia
7
acute stress
6
anorexia
4
anesthesia
4
fatigue
4
hepatomegaly
4
splenomegaly
3
polyuria
3
pain
2
polydipsia
2
thinning
2
diarrhea
1
sleepiness
1
cough
1
loss of equilibrium
1
blackout
1
hypothermia
1
Tissue anoxia
1
overweight
1
Anoxia
1
emaciation
1
inanition
1
tense
1
Decreased activity
1
tremor
1
vomiting
1
hyperoxia
1
stigma
1
Drug
NADH
95
lysine
52
Glucagon
37
citric acid
37
CAM
32
Leaf
25
Gel
21
Fructose
19
DNase I
16
Glycerol
11
lactose
11
ascorbate
10
ROS
9
Asn
8
Rosiglitazone
8
NH3
7
Alanine
7
Ethanol
7
MAP
6
Growth hormone
6
Growth hormone
6
Vitamin A
5
Diurnal
5
DMI
4
Aloe
4
caffeine
4
Forskolin
3
Troglitazone
3
CoCl2
3
Scopolamine
3
CoCl2
3
CDP
3
Bifidobacterium
2
Glycyrrhiza
2
ABC
2
G418
2
Myricetin
2
Fraction
2
Capsicum
2
Portal
2
Liraglutide
2
Vanilla
2
Posilac
2
Retinoic acid
2
Kenyan
2
Monit
2
THF
2
Monensin
2
Vitamin B
2
PCB
2
Mutagen
2
Citrus unshiu peel
1
Itraconazole
1
Emodin
1
Colombo
1
Aspartic Acid
1
Pentostam
1
TAT
1
niacin
1
Albumin
1
Honey
1
Phenylphosphate
1
Rasburicase
1
Salicylate
1
Glutathione
1
pyridoxal phosphate
1
Carbenoxolone
1
Trilostane
1
Riboflavin
1
EPA
1
Indomethacin
1
CER
1
Adenosine triphosphate
1
IL-2
1
Asthma
1
PFA
1
Nephron
1
DEX
1
Flavin
1
Theophylline
1
more...
Enzyme
phosphoenolpyruvate carboxykinase
4204
phosphoenolpyruvate carboxykinase
4143
phosphoenolpyruvate carboxykinase
4117
phosphoenolpyruvate carboxylase
1409
glucose-6-phosphatase
485
pyruvate kinase
336
pyruvate carboxylase
296
malate dehydrogenase
234
glucokinase
191
protein kinase
185
lactate dehydrogenase
109
rubisco
101
aspartate aminotransferase
98
fructose 1,6-bisphosphatase
97
phosphofructokinase
97
glucose-6-phosphate dehydrogenase
86
hexokinase
83
alanine aminotransferase
81
glutamate dehydrogenase
79
isocitrate dehydrogenase
79
glutamate dehydrogenase
79
glutamate dehydrogenase
79
citrate synthase
75
glutamine synthetase
75
AMP-activated protein kinase
68
pyruvate dehydrogenase
68
phosphorylase
59
isocitrate dehydrogenase
57
catalase
55
tyrosine aminotransferase
54
PPDK
52
pyruvate dehydrogenase
51
pyruvate dehydrogenase
51
isocitrate lyase
51
acetyl-CoA carboxylase
50
carbonic anhydrase
48
glyceraldehyde-3-phosphate dehydrogenase
47
superoxide dismutase
46
ATPase
44
glyceraldehyde-3-phosphate dehydrogenase
39
AMPK
38
glyceraldehyde-3-phosphate dehydrogenase
38
mitogen-activated protein kinase
38
glutaminase
37
lipoprotein lipase
37
chloramphenicol acetyltransferase
36
fumarase
36
CPT
36
succinate dehydrogenase
35
luciferase
35
glyceraldehyde-3-phosphate dehydrogenase
34
nitrate reductase
33
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
glyceraldehyde-3-phosphate dehydrogenase
32
nitrate reductase
32
nitrate reductase
32
aldolase
28
glycerol kinase
27
phosphoglycerate kinase
27
protein kinase C
25
AMPK
25
phosphatidylinositol 3-kinase
25
glutamate synthase
25
glutamate synthase
24
glutamate synthase
23
aconitase
23
alcohol dehydrogenase
23
6-phosphogluconate dehydrogenase
22
alpha-ketoglutarate dehydrogenase
22
oxaloacetate decarboxylase
22
6-phosphogluconate dehydrogenase
22
calcineurin
21
enolase
20
RNA polymerase
20
acetate kinase
18
succinic dehydrogenase
18
malate synthase
18
glycine decarboxylase
18
more...
Compound
glucose
1534
phosphate
362
Dec
308
CO2
281
DNA
254
cAMP
226
ATP
225
water
198
glycerol
174
oxygen
172
alanine
160
nitrogen
160
glutamate
154
AMP
150
NADP
139
acetate
131
PEP
127
NAD
126
glutamine
126
Insulin
121
NAD
106
serine
101
NADH
95
sodium
88
ADP
83
ammonium
82
ADP
79
GTP
79
ADP
79
ammonia
76
urea
72
pentose
72
pentose
72
pentose
72
pentose
72
2-oxoglutarate
71
manganese
71
oxalacetate
71
acetyl-CoA
70
salt
69
calcium
69
NADPH
67
glucose-6-phosphate
67
NADPH
67
lysine
62
ethanol
62
Clin
59
malic acid
59
nitrate
56
CoA
56
TCA
53
Mg2+
49
arginine
46
nicotinamide
43
sulfate
42
Asp
41
HCO
41
tyrosine
40
hydrogen
39
cysteine
39
threonine
38
Glucagon
37
proline
37
tryptophan
36
tryptophan
34
tryptophan
34
tryptophan
34
STZ
34
CAM
33
hexose
33
GDP
33
galactose
33
carbonate
33
leucine
33
retinoic acid
32
succinic acid
32
hexose
32
malic acid
32
hexose
32
hexose
32
more...