Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.32 (phosphoenolpyruvate carboxykinase)
4,204 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase 2811
phosphoenolpyruvate carboxylase 1280
insulin 863
glucose-6-phosphatase 481
pyruvate kinase 332
Mol 309
Sep 301
pyruvate carboxylase 279
glucagon 239
CO2 231
ATP 225
malate dehydrogenase 215
glucokinase 188
PEPCK 168
phosphatase 150
AMP 143
NADP 123
NAD 106
lactate dehydrogenase 106
fructose-1,6-bisphosphatase 98
PEP 97
NADH 96
NADP-malic enzyme 90
aspartate aminotransferase 89
Bot 86
phosphofructokinase 84
hexokinase 83
glucocorticoid receptor 83
fatty acid synthase 82
glucose transporter 81
PCK1 81
peroxisome proliferator-activated receptor 80
glutamate dehydrogenase 79
ADP 79
GTP 78
glutamine synthetase 75
citrate synthase 72
NADPH 67
insulin receptor 65
PEPCK-C 65
glucose-6-phosphate dehydrogenase 63
glycogen synthase 62
alanine aminotransferase 59
leptin 59
isocitrate dehydrogenase 57
growth hormone 56
IRS-1 54
pyruvate dehydrogenase 52
NMR 51
AMP-activated protein kinase 51
G6Pase 50
TAT 50
polypeptide 49
acetyl-CoA carboxylase 48
albumin 48
TCA 48
glycogen phosphorylase 47
protein kinase B 47
carbonic anhydrase 47
fructose 1,6-bisphosphatase 46
catalase 46
NAD-malic enzyme 45
superoxide dismutase 43
peroxisome proliferator-activated receptor gamma 41
rhabdomyosarcoma 41
EBP 39
proximal tubule 39
PGC 39
fused 38
ATPase 38
lipoprotein lipase 37
glutaminase 33
Pyruvate carboxylase 32
glyceraldehyde-3-phosphate dehydrogenase 32
GDP 32
CAM 32
carboxylating 30
reductase 30
AKT 30
fumarase 29
more...
Disease
diabetes 265
hyperglycemia 176
hepatocellular carcinoma 174
type 2 diabetes 163
obesity 110
hypoglycemia 81
glucose intolerance 61
hyperinsulinemia 53
tumor 46
cancer 44
fatty liver 43
CAM 33
metabolic syndrome 29
cold 26
SDS 24
idiopathic thrombocytopenic purpura 21
dyslipidemia 20
mole 18
mole 18
depression 18
hypertension 15
hyperlipidemia 14
Mycobacterium 14
Benson 12
dehydration 11
sepsis 11
tuberculosis 11
sepsis 11
pheochromocytoma 10
GSH 10
hyperphagia 10
iron deficiency 10
PCC 9
Schistosoma mansoni 9
Adenovirus 9
ketosis 9
type 1 diabetes 8
chlorosis 8
tapeworm 7
metabolic disorder 7
Evans 7
lipodystrophy 7
FAS 7
herpes simplex 7
schistosomiasis 7
tumor growth 7
lactic acidosis 6
Echinococcus 6
sudden infant death syndrome 6
worms 6
ischemia 6
malnutrition 6
vitamin A deficiency 6
leukemia 6
cardiovascular disease 6
AIN 5
virus infection 5
pertussis 5
endotoxic shock 5
Brown 5
West 5
malaria 5
liver cancer 5
wasting syndrome 5
tumorigenesis 5
infectious diseases 5
liver disease 5
carcinogenesis 5
renal disease 5
renal tubular acidosis 4
Mohr 4
seminal vesicles 4
cytomegalovirus 4
chronic renal failure 4
overnutrition 4
PDB 4
HIV 4
Hymenolepis 4
alcoholic fatty liver 4
hyperthyroidism 4
more...
Symptom
starvation 116
acidity 30
exhaustion 9
cachexia 7
acute stress 6
anorexia 4
anesthesia 4
fatigue 4
hepatomegaly 4
splenomegaly 3
polyuria 3
pain 2
polydipsia 2
thinning 2
diarrhea 1
sleepiness 1
cough 1
loss of equilibrium 1
blackout 1
hypothermia 1
Tissue anoxia 1
overweight 1
Anoxia 1
emaciation 1
inanition 1
tense 1
Decreased activity 1
tremor 1
vomiting 1
hyperoxia 1
stigma 1
Drug
NADH 95
lysine 52
Glucagon 37
citric acid 37
CAM 32
Leaf 25
Gel 21
Fructose 19
DNase I 16
Glycerol 11
lactose 11
ascorbate 10
ROS 9
Asn 8
Rosiglitazone 8
NH3 7
Alanine 7
Ethanol 7
MAP 6
Growth hormone 6
Growth hormone 6
Vitamin A 5
Diurnal 5
DMI 4
Aloe 4
caffeine 4
Forskolin 3
Troglitazone 3
CoCl2 3
Scopolamine 3
CoCl2 3
CDP 3
Bifidobacterium 2
Glycyrrhiza 2
ABC 2
G418 2
Myricetin 2
Fraction 2
Capsicum 2
Portal 2
Liraglutide 2
Vanilla 2
Posilac 2
Retinoic acid 2
Kenyan 2
Monit 2
THF 2
Monensin 2
Vitamin B 2
PCB 2
Mutagen 2
Citrus unshiu peel 1
Itraconazole 1
Emodin 1
Colombo 1
Aspartic Acid 1
Pentostam 1
TAT 1
niacin 1
Albumin 1
Honey 1
Phenylphosphate 1
Rasburicase 1
Salicylate 1
Glutathione 1
pyridoxal phosphate 1
Carbenoxolone 1
Trilostane 1
Riboflavin 1
EPA 1
Indomethacin 1
CER 1
Adenosine triphosphate 1
IL-2 1
Asthma 1
PFA 1
Nephron 1
DEX 1
Flavin 1
Theophylline 1
more...
Enzyme
phosphoenolpyruvate carboxykinase 4204
phosphoenolpyruvate carboxykinase 4143
phosphoenolpyruvate carboxykinase 4117
phosphoenolpyruvate carboxylase 1409
glucose-6-phosphatase 485
pyruvate kinase 336
pyruvate carboxylase 296
malate dehydrogenase 234
glucokinase 191
protein kinase 185
lactate dehydrogenase 109
rubisco 101
aspartate aminotransferase 98
fructose 1,6-bisphosphatase 97
phosphofructokinase 97
glucose-6-phosphate dehydrogenase 86
hexokinase 83
alanine aminotransferase 81
glutamate dehydrogenase 79
isocitrate dehydrogenase 79
glutamate dehydrogenase 79
glutamate dehydrogenase 79
citrate synthase 75
glutamine synthetase 75
AMP-activated protein kinase 68
pyruvate dehydrogenase 68
phosphorylase 59
isocitrate dehydrogenase 57
catalase 55
tyrosine aminotransferase 54
PPDK 52
pyruvate dehydrogenase 51
pyruvate dehydrogenase 51
isocitrate lyase 51
acetyl-CoA carboxylase 50
carbonic anhydrase 48
glyceraldehyde-3-phosphate dehydrogenase 47
superoxide dismutase 46
ATPase 44
glyceraldehyde-3-phosphate dehydrogenase 39
AMPK 38
glyceraldehyde-3-phosphate dehydrogenase 38
mitogen-activated protein kinase 38
glutaminase 37
lipoprotein lipase 37
chloramphenicol acetyltransferase 36
fumarase 36
CPT 36
succinate dehydrogenase 35
luciferase 35
glyceraldehyde-3-phosphate dehydrogenase 34
nitrate reductase 33
nitrate reductase 32
nitrate reductase 32
nitrate reductase 32
glyceraldehyde-3-phosphate dehydrogenase 32
nitrate reductase 32
nitrate reductase 32
aldolase 28
glycerol kinase 27
phosphoglycerate kinase 27
protein kinase C 25
AMPK 25
phosphatidylinositol 3-kinase 25
glutamate synthase 25
glutamate synthase 24
glutamate synthase 23
aconitase 23
alcohol dehydrogenase 23
6-phosphogluconate dehydrogenase 22
alpha-ketoglutarate dehydrogenase 22
oxaloacetate decarboxylase 22
6-phosphogluconate dehydrogenase 22
calcineurin 21
enolase 20
RNA polymerase 20
acetate kinase 18
succinic dehydrogenase 18
malate synthase 18
glycine decarboxylase 18
more...
Compound
glucose 1534
phosphate 362
Dec 308
CO2 281
DNA 254
cAMP 226
ATP 225
water 198
glycerol 174
oxygen 172
alanine 160
nitrogen 160
glutamate 154
AMP 150
NADP 139
acetate 131
PEP 127
NAD 126
glutamine 126
Insulin 121
NAD 106
serine 101
NADH 95
sodium 88
ADP 83
ammonium 82
ADP 79
GTP 79
ADP 79
ammonia 76
urea 72
pentose 72
pentose 72
pentose 72
pentose 72
2-oxoglutarate 71
manganese 71
oxalacetate 71
acetyl-CoA 70
salt 69
calcium 69
NADPH 67
glucose-6-phosphate 67
NADPH 67
lysine 62
ethanol 62
Clin 59
malic acid 59
nitrate 56
CoA 56
TCA 53
Mg2+ 49
arginine 46
nicotinamide 43
sulfate 42
Asp 41
HCO 41
tyrosine 40
hydrogen 39
cysteine 39
threonine 38
Glucagon 37
proline 37
tryptophan 36
tryptophan 34
tryptophan 34
tryptophan 34
STZ 34
CAM 33
hexose 33
GDP 33
galactose 33
carbonate 33
leucine 33
retinoic acid 32
succinic acid 32
hexose 32
malic acid 32
hexose 32
hexose 32
more...