Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:4.1.1.32 (
phosphoenolpyruvate carboxykinase
)
4,204
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
phosphoenolpyruvate carboxykinase
2811
phosphoenolpyruvate carboxylase
1280
insulin
863
glucose-6-phosphatase
481
pyruvate kinase
332
Mol
309
Sep
301
pyruvate carboxylase
279
glucagon
239
CO2
231
ATP
225
malate dehydrogenase
215
glucokinase
188
PEPCK
168
phosphatase
150
AMP
143
NADP
123
NAD
106
lactate dehydrogenase
106
fructose-1,6-bisphosphatase
98
PEP
97
NADH
96
NADP-malic enzyme
90
aspartate aminotransferase
89
Bot
86
phosphofructokinase
84
hexokinase
83
glucocorticoid receptor
83
fatty acid synthase
82
glucose transporter
81
PCK1
81
peroxisome proliferator-activated receptor
80
glutamate dehydrogenase
79
ADP
79
GTP
78
glutamine synthetase
75
citrate synthase
72
NADPH
67
insulin receptor
65
PEPCK-C
65
glucose-6-phosphate dehydrogenase
63
glycogen synthase
62
leptin
59
alanine aminotransferase
59
isocitrate dehydrogenase
57
growth hormone
56
IRS-1
54
pyruvate dehydrogenase
52
AMP-activated protein kinase
51
NMR
51
TAT
50
G6Pase
50
polypeptide
49
albumin
48
acetyl-CoA carboxylase
48
TCA
48
glycogen phosphorylase
47
protein kinase B
47
carbonic anhydrase
47
fructose 1,6-bisphosphatase
46
catalase
46
NAD-malic enzyme
45
superoxide dismutase
43
rhabdomyosarcoma
41
peroxisome proliferator-activated receptor gamma
41
proximal tubule
39
EBP
39
PGC
39
ATPase
38
fused
38
lipoprotein lipase
37
glutaminase
33
CAM
32
Pyruvate carboxylase
32
GDP
32
glyceraldehyde-3-phosphate dehydrogenase
32
reductase
30
AKT
30
carboxylating
30
fumarase
29
hemoglobin
29
cytokine
29
TNF
29
epididymal
29
CREB
28
decarboxylating
28
threonine
28
nuclear receptor
28
NADP-ME
27
PCK2
27
metallothionein
27
adiponectin
26
tumor necrosis factor
26
AMPK
25
casein
24
SDS
24
insulin-like growth factor
24
phosphatidylinositol 3-kinase
24
glycolytic enzyme
24
Gen
23
GLUT4
23
6-phosphogluconate dehydrogenase
22
carnitine palmitoyltransferase
22
NAD-ME
22
STZ
22
Pseudomonas
22
alcohol dehydrogenase
22
histone
21
NAD+
21
thyroid hormone
21
ubiquitin
20
aconitase
20
glucose transporter 4
20
enolase
20
phosphate-activated glutaminase
20
HDL
20
endoplasmic reticulum
20
cAMP-response element
19
phosphoglycerate kinase
19
sterol regulatory element-binding protein
19
IL-6
18
SHP
18
collagen
18
PEPCK-M
18
IDP
18
mTOR
18
adenylate kinase
17
IGF-I
17
C/EBP alpha
17
phosphodiesterase
17
lipopolysaccharide
17
forkhead transcription factor
17
protein phosphatase
17
thymidine kinase
17
PI3K
16
transferrin
16
hormone-sensitive lipase
16
glycine decarboxylase
16
nuclear protein
16
ACL
16
phosphoinositide 3-kinase
16
housekeeping
16
glycerol kinase
16
alkaline phosphatase
16
DNase I
16
nitric oxide synthase
15
calmodulin
15
cAMP response element-binding protein
15
Glucose-6-phosphatase
15
carbamoylphosphate synthetase
15
insulin receptor substrate
15
LL)
15
GLUT1
15
RNA polymerase II
15
argininosuccinate synthetase
15
cytochrome P450
14
glutathione peroxidase
14
ornithine transcarbamylase
14
HSD1
14
serine dehydratase
14
more...
Disease
diabetes
265
hyperglycemia
176
hepatocellular carcinoma
174
type 2 diabetes
163
obesity
110
hypoglycemia
81
glucose intolerance
61
hyperinsulinemia
53
tumor
46
cancer
44
fatty liver
43
CAM
33
metabolic syndrome
29
cold
26
SDS
24
idiopathic thrombocytopenic purpura
21
dyslipidemia
20
mole
18
mole
18
depression
18
hypertension
15
Mycobacterium
14
hyperlipidemia
14
Benson
12
tuberculosis
11
sepsis
11
dehydration
11
sepsis
11
hyperphagia
10
GSH
10
iron deficiency
10
pheochromocytoma
10
Adenovirus
9
Schistosoma mansoni
9
PCC
9
ketosis
9
type 1 diabetes
8
chlorosis
8
herpes simplex
7
FAS
7
tapeworm
7
lipodystrophy
7
schistosomiasis
7
tumor growth
7
metabolic disorder
7
Evans
7
leukemia
6
malnutrition
6
worms
6
lactic acidosis
6
ischemia
6
Echinococcus
6
vitamin A deficiency
6
cardiovascular disease
6
sudden infant death syndrome
6
malaria
5
Brown
5
AIN
5
pertussis
5
renal disease
5
wasting syndrome
5
virus infection
5
liver cancer
5
West
5
liver disease
5
tumorigenesis
5
carcinogenesis
5
endotoxic shock
5
infectious diseases
5
renal tubular acidosis
4
chronic renal failure
4
seminal vesicles
4
Chagas
4
Mohr
4
HIV
4
breast cancer
4
Hymenolepis
4
cytomegalovirus
4
hyperthyroidism
4
fits
4
alcoholic fatty liver
4
Infection
4
PDB
4
overnutrition
4
PER
3
hepatitis B
3
diabetic nephropathy
3
carcinoma
3
lung cancer
3
endocrine disorder
3
hepatitis C
3
multiple myeloma
3
thiamine deficiency
3
fascioliasis
3
colon cancer
3
cholestasis
3
hepatitis
3
atherosclerosis
3
liver cancer
3
wasting
3
Syndrome
3
Pituitary
3
neuroblastoma
3
metabolic alkalosis
3
Mycoplasma
3
polycystic ovary syndrome
3
melanoma
3
PGA
3
gestational diabetes mellitus
3
cerebral ischemia
3
insulinoma
3
hypothyroidism
2
Recruitment
2
adrenal insufficiency
2
epilepsy
2
leprosy
2
Leigh syndrome
2
chronic hepatitis
2
Chronic hepatitis C
2
ash
2
suicide
2
KMS
2
immunodeficiency
2
chronic disease
2
SEM
2
hepatic porphyria
2
zoonosis
2
tumor progression
2
rheumatoid arthritis
2
Biotin deficiency
2
sarcoma
2
porphyria cutanea tarda
2
Cryptococcus neoformans
2
pH increased
2
stroke
2
NAME
2
immunopathology
2
Brucella abortus
2
KMS
2
infestation
2
Blocking
2
retinopathy of prematurity
2
cirrhosis
2
arthritis
2
potassium deficiency
2
porphyria
2
MODY
2
peritonitis
2
Robinson
2
Alzheimer's disease
2
vagina
2
AD1
2
brucellosis
2
adenocarcinoma
2
African trypanosomiasis
2
inflammatory bowel disease
2
mammary tumor
2
diabetic hyperglycemia
2
non-small cell lung cancer
2
magnesium deficiency
2
more...
Symptom
starvation
116
acidity
30
exhaustion
9
cachexia
7
acute stress
6
anorexia
4
anesthesia
4
fatigue
4
hepatomegaly
4
splenomegaly
3
polyuria
3
pain
2
polydipsia
2
thinning
2
diarrhea
1
sleepiness
1
cough
1
loss of equilibrium
1
blackout
1
hypothermia
1
Tissue anoxia
1
overweight
1
Anoxia
1
emaciation
1
inanition
1
tense
1
Decreased activity
1
tremor
1
vomiting
1
hyperoxia
1
stigma
1
Drug
NADH
95
lysine
52
Glucagon
37
citric acid
37
CAM
32
Leaf
25
Gel
21
Fructose
19
DNase I
16
Glycerol
11
lactose
11
ascorbate
10
ROS
9
Asn
8
Rosiglitazone
8
Alanine
7
NH3
7
Ethanol
7
Growth hormone
6
MAP
6
Growth hormone
6
Diurnal
5
Vitamin A
5
Aloe
4
caffeine
4
DMI
4
CoCl2
3
Forskolin
3
Troglitazone
3
Scopolamine
3
CDP
3
CoCl2
3
Bifidobacterium
2
Kenyan
2
Glycyrrhiza
2
ABC
2
Monit
2
G418
2
Myricetin
2
Monensin
2
Liraglutide
2
Capsicum
2
Posilac
2
Vanilla
2
Fraction
2
Retinoic acid
2
THF
2
Portal
2
PCB
2
Vitamin B
2
Mutagen
2
Citrus unshiu peel
1
Itraconazole
1
Emodin
1
Colombo
1
Aspartic Acid
1
Pentostam
1
TAT
1
niacin
1
Albumin
1
Honey
1
Phenylphosphate
1
Rasburicase
1
Salicylate
1
Glutathione
1
pyridoxal phosphate
1
1-Deoxynojirimycin
1
Trilostane
1
Riboflavin
1
EPA
1
CER
1
ampicillin
1
Adenosine triphosphate
1
IL-2
1
Carbenoxolone
1
balanced salt solution
1
Indomethacin
1
Calan
1
Asthma
1
PFA
1
Gemfibrozil
1
Nephron
1
DEX
1
Dermatol
1
Theophylline
1
AGG
1
Flavin
1
Sodium sulfate
1
Asparaginase
1
Triclosan
1
Orphan
1
Dasatinib
1
IL-11
1
CDX
1
CaCl2
1
CaCl2
1
Glutamic acid
1
Vitamin B12
1
Atropine
1
Cottonseed oil
1
CDX
1
Carotenoid
1
Clofibrate
1
Isoptin
1
PTC
1
p-Chlorophenyl
1
ALA
1
TAC
1
Sulfopyruvate
1
CaCl2
1
Enrofloxacin
1
Valsartan
1
vitamin E
1
Citric acid
1
FAD
1
EE2
1
Pyridoxamine
1
PTH
1
Nipradilol
1
Emodin
1
Heme
1
Aminoguanidine
1
Arsenic trioxide
1
Nephron
1
RFP
1
Acyclovir
1
MRC
1
Enzyme
phosphoenolpyruvate carboxykinase
4204
phosphoenolpyruvate carboxykinase
4143
phosphoenolpyruvate carboxykinase
4117
phosphoenolpyruvate carboxylase
1409
glucose-6-phosphatase
485
pyruvate kinase
336
pyruvate carboxylase
296
malate dehydrogenase
234
glucokinase
191
protein kinase
185
lactate dehydrogenase
109
rubisco
101
aspartate aminotransferase
98
fructose 1,6-bisphosphatase
97
phosphofructokinase
97
glucose-6-phosphate dehydrogenase
86
hexokinase
83
alanine aminotransferase
81
glutamate dehydrogenase
79
isocitrate dehydrogenase
79
glutamate dehydrogenase
79
glutamate dehydrogenase
79
glutamine synthetase
75
citrate synthase
75
pyruvate dehydrogenase
68
AMP-activated protein kinase
68
phosphorylase
59
isocitrate dehydrogenase
57
catalase
55
tyrosine aminotransferase
54
PPDK
52
isocitrate lyase
51
pyruvate dehydrogenase
51
pyruvate dehydrogenase
51
acetyl-CoA carboxylase
50
carbonic anhydrase
48
glyceraldehyde-3-phosphate dehydrogenase
47
superoxide dismutase
46
ATPase
44
glyceraldehyde-3-phosphate dehydrogenase
39
mitogen-activated protein kinase
38
glyceraldehyde-3-phosphate dehydrogenase
38
AMPK
38
lipoprotein lipase
37
glutaminase
37
fumarase
36
chloramphenicol acetyltransferase
36
CPT
36
succinate dehydrogenase
35
luciferase
35
glyceraldehyde-3-phosphate dehydrogenase
34
nitrate reductase
33
nitrate reductase
32
glyceraldehyde-3-phosphate dehydrogenase
32
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
nitrate reductase
32
aldolase
28
glycerol kinase
27
phosphoglycerate kinase
27
protein kinase C
25
glutamate synthase
25
phosphatidylinositol 3-kinase
25
AMPK
25
glutamate synthase
24
aconitase
23
glutamate synthase
23
alcohol dehydrogenase
23
alpha-ketoglutarate dehydrogenase
22
6-phosphogluconate dehydrogenase
22
6-phosphogluconate dehydrogenase
22
oxaloacetate decarboxylase
22
calcineurin
21
enolase
20
RNA polymerase
20
succinic dehydrogenase
18
malate synthase
18
ornithine transcarbamylase
18
acetate kinase
18
glycine decarboxylase
18
adenylate cyclase
17
alkaline phosphatase
17
adenylate kinase
17
phosphodiesterase
17
thymidine kinase
17
phosphoinositide 3-kinase
16
fumarate reductase
16
hormone-sensitive lipase
16
argininosuccinate synthetase
16
focal adhesion kinase
15
glycerol-3-phosphate dehydrogenase
15
peroxidase
15
glycerol-3-phosphate dehydrogenase
15
sucrose synthase
15
carbamoylphosphate synthetase
15
11beta-hydroxysteroid dehydrogenase
14
complex I
14
glutathione peroxidase
14
trypsin
14
EC 1.1.1.40
13
ACS
13
CPT
13
lipase
13
phosphoglucose isomerase
13
CPT
13
acetyl-CoA synthetase
12
tryptophan 2,3-dioxygenase
12
GSK
12
beta-glucuronidase
12
invertase
12
proteasome
12
ascorbate peroxidase
11
PDK1
11
collagenase
11
acyl-CoA oxidase
11
glutathione reductase
11
arginase
11
6-phosphofructo-2-kinase
11
propionyl-CoA carboxylase
10
citrate lyase
10
phosphoenolpyruvate synthase
10
propionyl-CoA carboxylase
10
CPS
10
aspartokinase
10
PTA
10
reverse transcriptase
10
ERK
9
NADPH oxidase
9
diaphorase
9
MDH
9
asparagine synthetase
9
MDH
9
PEP phosphatase
9
AMP-activated kinase
9
diacylglycerol acyltransferase
9
pyruvate:ferredoxin oxidoreductase
8
hydroxypyruvate reductase
8
hydroxypyruvate reductase
8
NO synthase
8
hydrogenase
8
ADP-glucose pyrophosphorylase
8
nitrogenase
8
phosphoglucomutase
8
transhydrogenase
8
NADPH oxidase
8
ornithine decarboxylase
8
hydrogenase
8
nitrite reductase
7
NADH dehydrogenase
7
acyl-CoA dehydrogenase
7
gamma-glutamyl transpeptidase
7
HMG-CoA synthase
7
nitrite reductase
7
cytochrome oxidase
7
phosphoribulokinase
7
phenylalanine hydroxylase
7
formate dehydrogenase
7
PGM
7
protein phosphatase 2A
7
more...
Compound
glucose
1534
phosphate
362
Dec
308
CO2
281
DNA
254
cAMP
226
ATP
225
water
198
glycerol
174
oxygen
172
nitrogen
160
alanine
160
glutamate
154
AMP
150
NADP
139
acetate
131
PEP
127
glutamine
126
NAD
126
Insulin
121
NAD
106
serine
101
NADH
95
sodium
88
ADP
83
ammonium
82
GTP
79
ADP
79
ADP
79
ammonia
76
pentose
72
pentose
72
pentose
72
urea
72
pentose
72
manganese
71
oxalacetate
71
2-oxoglutarate
71
acetyl-CoA
70
calcium
69
salt
69
NADPH
67
glucose-6-phosphate
67
NADPH
67
ethanol
62
lysine
62
Clin
59
malic acid
59
nitrate
56
CoA
56
TCA
53
Mg2+
49
arginine
46
nicotinamide
43
sulfate
42
HCO
41
Asp
41
tyrosine
40
cysteine
39
hydrogen
39
threonine
38
proline
37
Glucagon
37
tryptophan
36
STZ
34
tryptophan
34
tryptophan
34
tryptophan
34
carbonate
33
galactose
33
CAM
33
leucine
33
hexose
33
GDP
33
retinoic acid
32
hexose
32
succinic acid
32
hexose
32
hexose
32
malic acid
32
malic acid
31
malic acid
31
Pyruvate
30
Malate
30
Lactate
30
NH2
30
TNF
29
methionine
29
iron
28
Gly
28
asparagine
28
Dexamethasone
28
cadmium
27
nitric oxide
27
Sucrose
27
His
27
potassium
25
alloxan
25
Phe
24
SDS
24
aspartic acid
24
phosphorus
22
alcohol dehydrogenase
22
aspartic acid
22
PEG
21
ITP
21
acetic acid
20
aspartic acid
19
isocitrate
19
aspartic acid
19
Fructose
19
succinic acid
18
succinic acid
18
succinic acid
18
succinic acid
18
glutamic acid
18
Glycogen
18
IDP
18
dicarboxylic acid
18
Carbon
17
zinc
17
methanol
17
H2O2
17
cobalt
16
Phytol
15
PEG
15
Phytol
15
Glutamate
15
Pyruvate kinase
14
Ile
14
Glutamine
14
CPT
13
oxalate
13
adenylate
13
copper
13
Chlorophyll
13
Glucose 6-phosphate
13
valine
13
CPT
13
CIT
13
Ribulose
12
isoleucine
12
malonyl-CoA
12
NO3
11
GSH
11
CAT
11
CAT
11
isoleucine
11
cyanide
11
palmitic acid
11
GAP
11
ATF
11
Flux
11
CAT
11
GSH
11
silver
10
PPi
9
Salt
9
xylose
9
HCl
8
more...