Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.15 (glutamate decarboxylase)
 2,169 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
glutamate decarboxylase 13.8
GPR155 11.8
Succinate semialdehyde dehydrogenase 11.5
GAD2 11.4
GAD1 11.3
methyl-CpG binding domain protein 1 11.3
GAD67 11.2
Munc-18-3 11.0
GAD65 11.0
GABA transaminase 10.9
cysteine sulfinic acid decarboxylase 10.9
Tetraspanin-7 10.8
GAD 10.7
estrogen receptor variant 10.7
succinate semialdehyde dehydrogenase 10.6
leukocyte antigen class II 10.5
Glutamate decarboxylase 1 10.5
AGBL1 10.5
ICA12 10.5
cysteine dioxygenase type 1 10.5
succinic semialdehyde dehydrogenase 10.5
4-aminobutyrate aminotransferase 10.5
HLA-DRB1*0402 10.3
ZNHIT3 10.3
Cysteine sulfinic acid decarboxylase 10.3
alpha-actinin 2 10.3
ribosomal protein S21 10.1
zinc transporter 8 10.1
GAT-2 10.0
Ornithine aminotransferase 10.0
adenylyl cyclase type V 10.0
preprotachykinin B 10.0
SSADH 10.0
vesicular GABA transporter 9.9
GSD1a 9.8
annexin VIII 9.6
NAV3 9.5
ErbB3-binding protein 1 9.5
GPHN 9.5
CDO1 9.4
gamma-amino butyric acid 9.3
phosphoinositide phospholipase C 9.2
CSAD 9.2
UBASH3A 9.1
succinate-semialdehyde dehydrogenase 9.1
GPR158 9.0
insulinoma-associated protein 2 9.0
TRK-fused gene 9.0
GABA transporter 9.0
IA-2 9.0
FRAT1 8.9
serine:pyruvate aminotransferase 8.9
TMP21 8.9
conserved dopamine neurotrophic factor 8.9
PKDL 8.8
choline acetyltransferase 8.8
PKD1L3 8.8
GABRD 8.8
MYO3A 8.8
Autoantigen 8.8
Syntaxin-binding protein 1 8.7
SDF-2 8.7
phosphate-activated glutaminase 8.6
ICA69 8.6
protein phosphatase inhibitor-1 8.6
KCTD12 8.5
choline acetylase 8.5
HLA DQB1 8.5
connexin-36 8.5
pyridoxal kinase 8.5
Choline acetyltransferase 8.5
DPPX 8.4
PDI1 8.4
synaptoporin 8.4
pyrroline-5-carboxylate synthetase 8.4
GABRA3 8.3
IDDM1 8.3
RASGRP1 8.3
MKK5 8.3
Succinic semialdehyde dehydrogenase 8.2
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Disease
GAD 10.2
GPHN 9.6
NF4 9.4
Aluminum intoxication 9.3
IDDM12 9.3
Autoimmune Diabetes 8.8
Morphine dependence 8.3
adaptation reaction 8.0
SPS 7.9
ARH 7.8
audiogenic epilepsy 7.8
other autoimmune disease 7.8
IDDM2 7.7
HHP 7.4
Oxygen toxicity 7.3
encephalomyelopathy 7.2
KCS 7.1
CLN5 6.9
ALS2 6.9
MICA 6.6
Retinal ischemia 6.6
audiogenic seizure 6.5
OBX 6.1
vitamin B6 deficiency 6.0
ketosis 5.9
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy 5.8
hypoglycemic coma 5.8
type 1 diabetes 5.7
GS1 5.7
choreoathetosis 5.6
GM1 gangliosidosis 5.6
petit mal 5.5
SPS 5.5
insulinoma 5.5
glutaric aciduria 5.4
Fallopian tube 5.3
Wolfram syndrome 5.2
MODY 5.1
generalized seizure 5.1
varices 5.1
Varicella zoster 5.0
INS 4.9
status epilepticus 4.9
autoimmune thyroid disease 4.9
monoarthritis 4.9
hereditary motor and sensory neuropathy 4.8
neuronal ceroid lipofuscinosis 4.8
Venezuelan equine encephalitis 4.7
hepatic coma 4.7
temporal lobe epilepsy 4.7
disinhibition 4.7
MELAS 4.6
Shigella flexneri 4.6
febrile convulsions 4.6
unipolar depression 4.6
AEM 4.6
tardive dyskinesia 4.5
Beard 4.5
corneal dystrophy 4.4
ganglioglioma 4.4
methylmalonic acidemia 4.4
Lennox-Gastaut syndrome 4.3
multi-infarct dementia 4.3
keratoconjunctivitis sicca 4.2
Pick's disease 4.2
Huntington's disease 4.2
CLN3 4.2
focal epilepsy 4.2
chronic cholecystitis 4.1
PND 4.1
Lennox-Gastaut syndrome 4.1
hepatic encephalopathy 4.1
HCI 4.1
hyperosmolality 4.0
MEC 4.0
diabetic ketoacidosis 4.0
fits 4.0
quadriparesis 4.0
prediabetes 3.9
Testes 3.9
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Symptom
Spontaneous nystagmus 7.8
Parkinsonian tremor 7.4
Deafferentation 6.4
skin irritant 6.3
disturbed balance 6.0
muscle stiffness 5.9
athetosis 5.8
lassitude 5.7
fasciculation 5.1
rundown 4.9
Decreased activity 4.8
Anoxia 4.7
ketonuria 4.7
seizures 4.4
eds 3.8
muscle rigidity 3.8
catatonia 3.7
acute stress 3.7
cerebellar ataxia 3.6
hypertonia 3.6
Neuropathic pain 3.4
hyperoxia 3.1
acidity 2.8
polydipsia 2.7
facial pain 2.6
paraparesis 2.4
lethargy 2.4
polyuria 2.3
tinnitus 2.2
memory loss 2.0
dystonia 1.8
chills 1.8
ataxia 1.5
cachexia 1.4
hypotonia 1.3
starvation 1.2
spasticity 1.2
exhaustion 1.1
analgesia 1.1
spasm 1.0
tremor 0.7
agitation 0.3
sleepiness 0.2
pain 0.2
functional recovery 0.1
anesthesia -0.3
dyspnea -0.9
diarrhea -1.0
Drug
pyridoxal phosphate 8.7
Pyridoxal phosphate 8.7
Gamma-Aminobutyric acid 8.6
GVG 8.1
Kainic acid 7.5
Pyridoxal 7.4
Idebenone 6.9
AraC 6.8
Lactic Acid 6.5
Monosodium glutamate 6.5
Vitamin B 6.4
Dihydroergotamine 6.3
Tween 40 6.2
Glutamic acid 5.9
Sodium valproate 5.5
Piracetam 5.4
Aminoguanidine 5.1
Epigallocatechin 5.0
Apomorphine 4.6
DPA 4.5
Pilocarpine 4.5
Alanine 4.4
DHT 3.7
DHT 3.7
Aloe 3.6
Pronase 3.5
ZnCl2 3.5
ZnCl2 3.5
Phenytoin 3.5
ALA 3.4
Glycyrrhiza 3.4
MgSO4 3.3
citric acid 3.2
Activin 3.1
PTC 3.1
Parkin 3.0
Parkin 3.0
Frontal 2.8
EPI 2.8
Glycerol 2.7
Fraction 2.5
ETS 2.5
ICI 2.4
FAD 2.4
Gel 2.3
CaCl2 2.2
CaCl2 2.2
lysine 2.2
CaCl2 2.2
NADH 2.0
PCP 2.0
niacin 2.0
MAP 1.9
THF 1.8
DNase I 1.8
nitroglycerin 1.7
Nephron 1.7
Ethanol 1.6
lactose 1.4
Histamine 1.4
CAM 1.3
Asn 1.3
Bifidobacterium 1.3
Indomethacin 1.2
Leaf 1.0
EE2 0.9
ABC 0.7
IFN-gamma 0.0
CSF -0.1
vitamin E -0.3
ascorbate -0.7
IL-2 -1.0
Cardiovasc -2.8
Enzyme
glutamate decarboxylase 13.8
EC 1.1.1.15 12.8
EC 1.2.1.16 11.3
GABA transaminase 11.1
aspartate 1-decarboxylase 11.0
glutaminase II 10.8
succinic semialdehyde dehydrogenase 10.5
CSAD 10.1
cysteine lyase 9.9
2-oxoglutarate decarboxylase 9.9
4-hydroxybutyrate dehydrogenase 9.8
sucrose-phosphatase 9.7
AAO3 9.1
pantothenate synthetase 8.9
choline acetyltransferase 8.8
D-serine dehydratase 8.6
acetylornithine aminotransferase 8.5
pyridoxal kinase 8.4
desulfinase 8.4
pyroglutamyl peptidase II 8.3
arginine decarboxylase 8.2
glutamine transaminase K 8.2
arginine decarboxylase 8.0
glutaminase 7.9
aromatic L-amino acid decarboxylase 7.8
diaminopimelate decarboxylase 7.6
polyamine oxidase 7.6
isoflavone reductase 7.5
homocysteine methyltransferase 7.5
CFA synthase 7.4
tyrosine phenol-lyase 7.4
acetolactate decarboxylase 7.2
phenylethanolamine N-methyltransferase 7.2
glutamate dehydrogenase 7.2
proline dehydrogenase 7.2
glutamate dehydrogenase 7.1
glutamate dehydrogenase 7.1
glutaryl-CoA dehydrogenase 7.1
glutamate synthase 7.1
glutamate synthase 7.0
glutamine synthetase 7.0
L-serine dehydratase 7.0
glutamate synthase 7.0
DOPA decarboxylase 7.0
xyloglucan endotransglycosylase 6.9
ornithine aminotransferase 6.9
bile salt hydrolase 6.9
tyrosine hydroxylase 6.8
glycerol dehydratase 6.7
alanine racemase 6.5
alpha-ketoglutarate dehydrogenase 6.5
histidine decarboxylase 6.5
pyroglutamate aminopeptidase 6.5
arginine deiminase 6.4
coproporphyrinogen III oxidase 6.4
histidyl-tRNA synthetase 6.3
glycerol 3-phosphate dehydrogenase 6.2
cinnamate 4-hydroxylase 6.2
NAD+ oxidoreductase 6.1
diamine oxidase 6.0
glutamic dehydrogenase 6.0
cysteine dioxygenase 6.0
NCED 6.0
ADE2 6.0
cutinase 5.9
coproporphyrinogen oxidase 5.8
pyruvate oxidase 5.8
pyruvate oxidase 5.8
SPS 5.8
pyruvate decarboxylase 5.7
PI-PLC 5.7
chalcone isomerase 5.7
tryptophan hydroxylase 5.6
acetolactate synthase 5.5
spermidine synthase 5.5
Omi/HtrA2 5.4
nucleotidase 5.4
tryptophanase 5.4
ornithine decarboxylase 5.4
catechol O-methyltransferase 5.2
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Compound
4-bromoisophthalic acid 13.8
3-phenylpentanoic acid 13.8
3-phenylpentanoic acid 13.8
3-phosphonoalanine 12.5
Chelidonic acid 11.8
3-MPA 10.6
3,3-dimethylglutarate 10.3
Gabaculine 10.2
TXP 9.6
gamma-aminobutyric acid 9.0
L-2,4-diaminobutyric acid 8.9
Homocarnosine 8.8
5-hydroxyisophthalic acid 8.8
5-hydroxyisophthalic acid 8.8
Methylazoxymethanol 8.4
GABA 8.2
GABA 8.1
Androsterone 7.9
L-cysteine sulfinic acid 7.9
Methyllycaconitine 7.8
DVC 7.7
Kainic acid 7.5
Kainic acid 7.5
Pyridoxal 7.4
D-Cycloserine 7.4
2,2,2-trichloroethanol 7.3
1-methylhistidine 7.3
Semicarbazide 7.2
Dihydroergotamine 7.2
PLP 7.1
beta-alanine 7.0
BZT 6.9
Pyridoxine 6.9
DCIP 6.8
Felbamate 6.7
cysteate 6.7
Amitraz 6.6
glutamate 6.6
2-oxoglutarate 6.6
Tiagabine 6.5
Muscimol 6.5
Picrotoxin 6.5
Picrotoxin 6.5
gamma-hydroxybutyric acid 6.4
6-Hydroxydopamine 6.4
Vigabatrin 6.4
MSG 6.4
MeODMT 6.3
Barbiturate 6.3
pentanedioic acid 6.3
IAA 6.3
Pyrroloquinoline quinone 6.2
THIP 6.2
Ornithine 6.2
glutamic acid 6.1
norvaline 6.1
IAA 6.1
norvaline 6.0
isopentane 6.0
butyric acid 6.0
NBQX 6.0
QNB 6.0
AET 5.9
Glutamate 5.9
oxalacetate 5.9
butyric acid 5.9
butyric acid 5.7
5-oxoproline 5.7
5-methylisoxazole 5.7
Cypermethrin 5.7
Letrozole 5.6
PH2 5.6
Baclofen 5.6
MEE 5.6
Methyllycaconitine 5.6
pyrroline-5-carboxylate 5.6
Spiperone 5.6
Bicuculline 5.5
Propionate 5.5
MPA 5.4
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