Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:4.1.1.15 (glutamate decarboxylase)
 2,169 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glutamate decarboxylase 2066
GABA 621
GAD 206
choline acetyltransferase 194
GAD65 192
GAD67 188
Sep 154
insulin 143
tyrosine hydroxylase 115
GABA transaminase 105
Mol 97
glutamic acid decarboxylase 71
parvalbumin 61
peroxidase 57
olfactory 57
axonal 52
somatostatin 47
CA1 47
glutamine synthetase 45
acetylcholinesterase 45
glutamate dehydrogenase 42
substance P 41
CA3 38
calbindin 37
calmodulin 37
vesicular GABA transporter 36
autoantigen 35
ATP 31
aspartate aminotransferase 31
GABA(A) receptor 30
GABA transporter 30
calretinin 30
glutaminase 29
GAD1 28
IA-2 27
neuropeptide Y 27
gamma-amino butyric acid 25
NMDA receptor 24
polypeptide 23
SDS 22
succinic semialdehyde dehydrogenase 21
cholecystokinin 20
Leu-enkephalin 20
CO2 20
lactate dehydrogenase 20
ornithine decarboxylase 18
GAD2 17
dopa decarboxylase 17
glutamate receptor 17
NMR 17
synaptophysin 16
nitric oxide synthase 16
glial fibrillary acidic protein 16
glucagon 15
HLA 15
Choline acetyltransferase 15
beta-endorphin 14
IDDM 14
neuronal nitric oxide synthase 14
brain-derived neurotrophic factor 14
AMP 13
nerve growth factor 13
glutamate transporter 13
vasopressin 13
cytokine 11
prolactin 11
asymmetrical 11
arginine decarboxylase 11
MICA 10
GABA(B) receptor 10
dynorphin 10
diamine oxidase 10
calcium-binding protein 10
c-fos 10
neural cell adhesion molecule 10
4-aminobutyrate aminotransferase 10
ATPase 9
tumor necrosis factor 9
CA4 9
adenylate cyclase 9
alanine aminotransferase 9
phosphate-activated glutaminase 9
PLP 9
ChAT 9
TCA 8
NADPH 8
Met 8
thyroid peroxidase 8
ionotropic 8
protein tyrosine phosphatase 8
fused 8
membrane-bound 8
oxytocin 8
5-hydroxytryptamine 8
histidine decarboxylase 8
DR4 8
SOD 7
dimeric 7
vesicular glutamate transporter 2 7
calcitonin 7
VGLUT1 7
neurotrophic factor 7
gut 7
IL-10 7
SNAP 7
cysteine sulfinic acid decarboxylase 7
pyrroline-5-carboxylate synthetase 7
Pseudomonas 7
NAD 7
succinate semialdehyde dehydrogenase 7
neurotensin 7
proinsulin 7
NADH 6
VGLUT2 6
polyamine oxidase 6
catalase 6
NADP 6
galanin 6
muscarinic receptor 6
phenylethanolamine N-methyltransferase 6
CA2 6
major histocompatibility complex 6
tyrosine phosphatase 6
ACTH 6
DARPP-32 6
tryptophan hydroxylase 6
vasoactive intestinal peptide (VIP) 6
HLA class II 6
CD56 6
glutamate binding 6
HLA-DQ 6
CD4 6
Gen 6
DR3 6
neurotrophin-3 6
human leukocyte antigen 5
bombesin 5
SCH 5
pyridoxal kinase 5
membrane protein 5
Glutamic acid decarboxylase 5
zinc transporter 8 5
opioid receptor 5
epidermal growth factor 5
calcium binding protein 5
orexin 5
Parvalbumin 5
transcriptional regulator 5
malate dehydrogenase 5
nicotinic acetylcholine receptor 5
prodynorphin 5
dopamine D1 receptor 5
estrogen receptor 5
gastrin 5
KCC2 5
proopiomelanocortin 5
gephyrin 5
IL-6 5
neuron-specific enolase 5
DCX 5
more...
Disease
GAD 206
diabetes 139
type 1 diabetes 75
epilepsy 56
schizophrenia 36
fits 34
varices 26
SDS 22
Parkinson's disease 22
autoimmune disease 20
ischemia 20
depression 18
Alzheimer's disease 18
Huntington's disease 17
status epilepticus 15
hypertension 14
SPS 14
cold 14
hypoglycemia 13
tumor 12
insulinoma 11
cancer 11
temporal lobe epilepsy 11
type 2 diabetes 10
MICA 10
cognitive impairment 8
cerebral ischemia 8
disinhibition 8
neuroblastoma 8
stroke 8
ketosis 8
parkinsonism 7
major depressive disorder 7
psychosis 7
encephalopathy 7
bipolar disorder 7
encephalitis 7
coma 6
tetanus 6
hyperglycemia 6
Shigella 6
pheochromocytoma 6
cleft palate 6
hepatic encephalopathy 5
SCH 5
PSA 5
Shigella flexneri 5
obesity 5
celiac disease 5
mimicry 5
chronic pain 5
cholera 5
autism 4
mole 4
dementia 4
PCC 4
tardive dyskinesia 4
rheumatoid arthritis 4
mole 4
Graves' disease 4
DBA 4
nystagmus 4
amyotrophic lateral sclerosis 4
hyperprolactinemia 4
hypothyroidism 4
dyskinesia 4
glucose intolerance 4
MRS 4
gastritis 3
diabetic ketoacidosis 3
immunodeficiency 3
herpes simplex 3
aggression 3
SEM 3
INS 3
alcoholism 3
memory impairment 3
Mycobacterium 3
NOD 3
worms 3
autoimmune thyroid disease 3
heart failure 3
ARH 3
prostate cancer 3
Frey 2
colitis 2
neuronal ceroid lipofuscinosis 2
tuberculosis 2
confusion 2
diabetic retinopathy 2
carcinoma 2
carcinogenesis 2
Best 2
Evans 2
petit mal 2
neurological disease 2
prediabetes 2
hepatitis B 2
lung cancer 2
focal epilepsy 2
respiratory failure 2
other autoimmune disease 2
uterus 2
Fallopian tube 2
SPS 2
CAM 2
chronic disease 2
plaque 2
Epstein 2
audiogenic seizure 2
listeriosis 2
Venezuelan equine encephalitis 2
suicide 2
anxiety disorders 2
migraine 2
epididymis 2
adenocarcinoma 2
multiple sclerosis 2
choreoathetosis 2
pertussis 2
movement disorder 2
Brown 2
anhedonia 2
mental illness 2
scrapie 2
immaturity 2
coxsackievirus 2
akinesia 2
virus infection 2
emotional stress 2
unipolar depression 2
iron deficiency 2
generalized seizure 2
cytomegalovirus 2
catalepsy 2
GSH 2
glioma 2
tumorigenesis 2
Autism spectrum disorder 2
Down syndrome 2
autoimmune thyroiditis 2
febrile convulsions 2
dehydration 1
OBX 1
Shiga 1
psychiatric diagnosis 1
cataract 1
illusion 1
bulimia nervosa 1
congenital hypothyroidism 1
systemic lupus erythematosus 1
cognitive deficit 1
hereditary motor and sensory neuropathy 1
oligodendroglioma 1
acute myocardial infarction 1
Krabbe disease 1
chronic cholecystitis 1
adenomyosis 1
MEC 1
EPI 1
more...
Symptom
seizures 118
pain 20
acidity 7
anesthesia 6
muscle stiffness 5
acute stress 4
starvation 4
analgesia 4
ataxia 3
hyperoxia 3
cerebellar ataxia 3
fasciculation 3
tremor 2
diarrhea 2
lethargy 2
dystonia 2
exhaustion 2
tinnitus 2
lassitude 1
catatonia 1
disturbed balance 1
sleepiness 1
Deafferentation 1
dyspnea 1
rundown 1
hypertonia 1
polyuria 1
hypotonia 1
facial pain 1
muscle rigidity 1
functional recovery 1
polydipsia 1
eds 1
spasticity 1
Anoxia 1
Spontaneous nystagmus 1
paraparesis 1
chills 1
memory loss 1
athetosis 1
skin irritant 1
Neuropathic pain 1
ketonuria 1
agitation 1
spasm 1
Decreased activity 1
cachexia 1
Parkinsonian tremor 1
Drug
pyridoxal phosphate 73
lysine 18
AraC 8
Kainic acid 8
Vitamin B 7
citric acid 6
NADH 6
Gel 5
Alanine 4
Pyridoxal phosphate 4
Nephron 4
MAP 4
lactose 3
Pyridoxal 3
GVG 3
Leaf 3
CSF 2
Asn 2
DNase I 2
FAD 2
Glutamic acid 2
Cardiovasc 2
DHT 2
DPA 2
THF 2
Apomorphine 2
IFN-gamma 2
ALA 2
CaCl2 2
CaCl2 2
nitroglycerin 2
ICI 2
DHT 2
CaCl2 2
Ethanol 2
Sodium valproate 1
PTC 1
Dihydroergotamine 1
ascorbate 1
EE2 1
Glycerol 1
MgSO4 1
Parkin 1
ZnCl2 1
Indomethacin 1
ABC 1
Piracetam 1
Parkin 1
Gamma-Aminobutyric acid 1
EPI 1
Bifidobacterium 1
Frontal 1
Pronase 1
Idebenone 1
IL-2 1
vitamin E 1
Monosodium glutamate 1
niacin 1
CAM 1
ZnCl2 1
Glycyrrhiza 1
Phenytoin 1
Tween 40 1
Aminoguanidine 1
Activin 1
Epigallocatechin 1
Histamine 1
ETS 1
PCP 1
Pilocarpine 1
Lactic Acid 1
Aloe 1
Fraction 1
Enzyme
glutamate decarboxylase 2169
choline acetyltransferase 198
GABA transaminase 122
tyrosine hydroxylase 113
peroxidase 61
glutamine synthetase 45
acetylcholinesterase 43
glutamate dehydrogenase 43
glutamate dehydrogenase 42
glutamate dehydrogenase 42
aspartate aminotransferase 31
glutaminase 31
succinic semialdehyde dehydrogenase 29
lactate dehydrogenase 22
alanine aminotransferase 19
protein kinase 19
ornithine decarboxylase 18
arginine decarboxylase 11
arginine decarboxylase 11
diamine oxidase 11
protein kinase C 10
cytochrome oxidase 10
adenylate cyclase 9
ATPase 9
DOPA decarboxylase 9
histidine decarboxylase 9
monoamine oxidase 8
alpha-ketoglutarate dehydrogenase 8
thyroid peroxidase 8
aromatic L-amino acid decarboxylase 8
NADPH-diaphorase 8
succinate dehydrogenase 8
NO synthase 8
glutamate synthase 7
beta-galactosidase 7
citrate synthase 7
glutamate synthase 7
glutamate synthase 7
phenylethanolamine N-methyltransferase 6
reverse transcriptase 6
trypsin 6
polyamine oxidase 6
pyruvate dehydrogenase 6
mitogen-activated protein kinase 6
catalase 6
CSAD 6
AMP-activated protein kinase 6
ornithine aminotransferase 6
tryptophan hydroxylase 6
malate dehydrogenase 6
RNA polymerase 5
pyridoxal kinase 5
phosphorylase 5
RNase 5
RNase 5
superoxide dismutase 5
arginine deiminase 5
NADPH oxidase 5
glutathione S-transferase 4
isocitrate dehydrogenase 4
phosphofructokinase 4
isocitrate dehydrogenase 4
urease 4
urease 4
diaphorase 4
nucleotidase 3
transcriptase 3
AMPK 3
caspase-3 3
pyruvate dehydrogenase 3
EC 1.2.1.16 3
glyceraldehyde-3-phosphate dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
AMPK 3
focal adhesion kinase 3
glyceraldehyde-3-phosphate dehydrogenase 3
hexokinase 3
transglutaminase 3
pyruvate decarboxylase 3
creatine kinase 3
phosphodiesterase 3
pyruvate dehydrogenase 3
PDE 3
6-phosphogluconate dehydrogenase 3
phospholipase C 3
6-phosphogluconate dehydrogenase 3
calcineurin 3
dopamine beta-hydroxylase 3
proline dehydrogenase 3
SPS 3
aldolase 3
alcohol dehydrogenase 2
proteasome 2
cystathionine beta-synthase 2
glutathione peroxidase 2
bile salt hydrolase 2
cutinase 2
aldehyde dehydrogenase 2
D-serine dehydratase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
NOS 2
2-oxoglutarate decarboxylase 2
aldehyde dehydrogenase 2
homocysteine methyltransferase 2
glycerol-3-phosphate dehydrogenase 2
phosphoenolpyruvate carboxykinase 2
pantothenate synthetase 2
S-adenosylmethionine decarboxylase 2
aldehyde dehydrogenase 2
GSK 2
phosphoenolpyruvate carboxykinase 2
phosphoenolpyruvate carboxylase 2
deaminase 2
phosphoenolpyruvate carboxykinase 2
cholinesterase 2
glyceraldehyde-3-phosphate dehydrogenase 2
arginase 2
glutathione reductase 2
aspartate 1-decarboxylase 2
gamma-glutamyl transpeptidase 2
PI-PLC 2
acetolactate synthase 2
NADPH oxidase 2
AST 2
glutaminase II 2
alanine racemase 2
CPR 2
glutaryl-CoA dehydrogenase 2
lysozyme 2
glycerol-3-phosphate dehydrogenase 2
beta-glucuronidase 2
luciferase 2
glyceraldehyde-3-phosphate dehydrogenase 2
fumarase 1
alpha-amylase 1
sialyltransferase 1
caspase-1 1
cathepsin K 1
sialyltransferase 1
sialyltransferase 1
glucokinase 1
AAO3 1
spermidine synthase 1
aconitase 1
L-serine dehydratase 1
glycerol dehydratase 1
carboxypeptidase Y 1
NCED 1
PAL 1
LasR 1
phytoene synthase 1
GRK2 1
cystathionine gamma-lyase 1
cysteine lyase 1
RNase H 1
E-2 1
ATP synthase 1
ACC synthase 1
GRK5 1
more...
Compound
GABA 690
GABA 642
gamma-aminobutyric acid 546
glutamate 496
Dec 143
phosphate 112
calcium 98
glucose 82
glutamic acid 79
DNA 75
glutamine 70
sodium 59
2-oxoglutarate 49
water 44
Clin 42
alanine 41
CO2 37
nitrogen 36
acetate 36
oxygen 34
ATP 31
methionine 29
cysteine 27
sulfate 27
arginine 26
Glutamate 26
butyric acid 25
butyric acid 25
butyric acid 25
Asp 25
noradrenaline 25
SDS 24
ammonium 23
lysine 22
tryptophan 21
tryptophan 21
NMDA 20
tryptophan 19
tryptophan 19
proline 18
beta-alanine 18
5-HT 18
nitric oxide 18
AMPA 17
silver 17
ammonia 16
vinyl 16
His 15
AMP 15
aspartic acid 15
PLP 15
Neuronal 15
potassium 15
salt 14
ethanol 14
zinc 14
aspartic acid 14
leucine 14
tyrosine 14
hydrogen 13
ornithine 13
Gly 13
IAA 13
ornithine 13
ornithine 13
IAA 13
ornithine 13
ornithine 13
L-DOPA 13
Insulin 12
serine 10
cAMP 10
fluorine 10
Phe 10
aspartic acid 9
glycerol 9
DEAE 9
TCA 9
galactose 9
aspartic acid 9
PEG 9
Cereb 9
Dopamine 8
Kainic acid 8
NADPH 8
Kainic acid 8
NADP 8
NADPH 8
retinoic acid 7
NAD 7
NAD 7
MPTP 6
propionic acid 6
NADH 6
propionic acid 6
isoxazole 6
ACTH 6
Triton X-100 6
aldehyde 6
Cardiol 6
aldehyde 6
succinic acid 5
MSG 5
cobalt 5
hydroxyindoleacetic acid 5
succinic acid 5
Yellow 5
nicotinamide 5
iron 5
Glutamine 5
urea 5
succinic acid 5
Lactate 5
succinic acid 5
succinic acid 5
threonine 5
Taurine 5
Muscimol 5
DBA 4
Bicuculline 4
Progesterone 4
NBQX 4
ETA 4
Diazepam 4
DBA 4
Lactic acid 4
pyrrolidine 4
nickel 4
adenylate 4
Mg2+ 4
TOF 4
Haloperidol 4
Alanine 4
asparagine 4
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4
acetyl-CoA 4
NTA 4
Baclofen 4
MAP 4
EDTA 4
pyrrolidine 4
5-methylisoxazole 4
QNB 4
EDTA 4
acetic acid 4
MPA 4
DBA 4
Haloperidol 4
MPA 4
hydroxylamine 4
chlorine 4
CoA 4
MPA 4
gamma-hydroxybutyric acid 4
Picrotoxin 3
Nicotine 3
Cysteine 3
COS 3
Gabaculine 3
Estrogen 3
more...