Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.4.4 (kinesin)
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Human Gene/Protein
kinesin light chain 2 12.6
KIF21B protein 12.6
KNSL3 12.6
F12 protein 12.6
BRCA2-associated factor 35 12.6
KIF13B protein 12.6
spermatogenesis associated 6 12.6
KIF5B protein 12.6
KIF3C protein 12.6
SifA and kinesin-interacting protein 12.6
FKIF2 12.6
KLC2 protein 12.6
TTC30B 12.6
kinesin 12.6
KIP3 12.5
KIF5A protein 12.3
GAKIN 12.3
KIF3C 12.2
PLEKHM2 12.2
kinesin heavy chain 12.1
KIFC2 12.1
KIF19A 12.0
KNS2 12.0
KIF3 12.0
KIF13A 12.0
KIF1C 12.0
Klp1 12.0
Eg5 12.0
KLC2 12.0
kinectin 12.0
MS-KIF18A 11.9
KIF13B 11.9
GRIF-1 11.9
KIF2 11.9
neuronal kinesin heavy chain 11.9
kinesin light chain 1 11.9
KIFC3 11.9
KIF21B 11.9
kinesin light chain 11.9
KIF1Bbeta 11.8
KIF3B 11.8
MKLP2 11.8
KIFC1 11.8
KLC1 11.8
KIF5C 11.8
kinesin 2 11.7
KIF1A 11.7
KIF16B 11.7
microtubule-based motor 11.7
HSET 11.6
serologically defined colon cancer antigen 3 11.6
KIF26B protein 11.6
dystrophin C-terminal region 11.6
intraflagellar transport 88 homolog 11.6
RanBP2L1 11.6
MAP7D2 11.6
MAP7D3 11.6
Kinesin light chain 11.6
Orosomucoid 2 11.6
Calsyntenin-1 11.6
PPFIA4 11.6
Kinesin family member 1B 11.6
D2LIC 11.6
RNF33 11.6
RBKIN 11.6
M6PR protein 11.6
KIF5A 11.6
KIF17 11.6
MCAK 11.6
TRAK1 11.6
TRAK2 11.6
kinesin-related protein 11.5
KIF3A 11.5
kinectin 1 11.5
KLC3 11.5
axonal transport of synaptic vesicles 11.5
KIF18A 11.4
syntabulin 11.4
kinesin-2 11.4
kinesin family member 1A 11.3
STARD9 11.3
ARFGAP2 11.3
KIF5B 11.2
KLP 11.2
KIAA1279 11.2
kinesin motor protein 11.1
kinesin family member 18A 11.0
tektin 1 11.0
PPFIA3 11.0
NGD5 11.0
kinesin heavy chain-like protein 11.0
PPFIA2 11.0
MAP7 11.0
EML4/ALK fusion 11.0
Myosin-Ic 11.0
RNB6 11.0
Nesca 11.0
KIAA0284 11.0
MAP7D1 11.0
NudCL 11.0
KIF15 11.0
kinesin-like protein 11.0
KAP3 11.0
KIFAP3 10.9
mitotic centromere-associated kinesin 10.9
KIF20B 10.8
Marlin-1 10.8
SPG10 10.8
motor protein 10.8
KIF14 10.8
kinesin superfamily protein 10.8
KIF4 10.8
Mitotic centromere-associated kinesin 10.7
PGs1 10.6
myosin-Ic 10.6
CENP-E 10.6
ADP-ribosylation factor-like protein 8B 10.6
PLK5 10.6
human ribosomal protein L38 10.6
Kinesin family member C1 10.6
SH2D6 10.6
FAM98B 10.6
synaptonemal complex protein 2 10.6
C11orf70 10.6
KIF26A 10.6
CHO1 10.6
KIF1B 10.5
DHC1b 10.5
KIF20A 10.5
FYCO1 10.5
JSAP1 10.5
IFT52 10.5
Dynein heavy chain 10.4
KSP 10.4
chromokinesin 10.4
KIF2C 10.4
KIF4A 10.4
caytaxin 10.3
pituitary tumor-transforming 3 10.3
rabkinesin-6 10.3
kinesin light chain 4 10.3
NESCA 10.3
Tog 10.3
microtubule-associated protein 7 10.3
Tubby-like protein 3 10.3
MAPK/MAK/MRK overlapping kinase 10.3
bicaudal D homolog 2 10.3
KIF12 10.3
TAS2R50 10.3
KIF9 10.3
hydroxysteroid dehydrogenase-like protein 10.3
MAPK8IP3 10.3
WDR8 10.3
Rabkinesin-6 10.3
HZW10 10.3
KIF18B 10.2
JIP1 10.2
HSPC117 10.2
KIF23 10.1
KIF26B 10.1
more...
Disease
GOSHS 11.0
SPG10 10.9
SPG30 10.3
CMT2F 9.7
CFEOM3 9.6
Intraocular Retinoblastoma 9.5
CMT2B2 9.5
CMT2C 9.2
Invasive Carcinoma 9.2
CDA III 8.7
AAA1 8.7
CMT2K 8.6
CFEOM1 8.5
CMT2D 8.3
Neuroaxonal dystrophy 8.0
CMT4A 8.0
BBS8 8.0
CMT2E 7.9
LIS1 7.6
urinary system cancer 7.4
USH1G 7.3
USH1B 7.3
JIP 7.2
HOPS 6.9
spastic paraplegia 6.8
Retinal damage 6.8
NPHP4 6.8
USH1C 6.4
PARK8 6.3
Hereditary spastic paraplegia 6.3
ABC-DLBCL 6.3
ACLS 6.2
SPG4 6.2
ASG 6.2
Bardet-Biedl syndrome 5.9
hereditary sensory neuropathy 5.8
pediatric solid tumor 5.7
CREST 5.7
lissencephaly 5.7
Morvan 5.4
NPHP1 5.4
PSN 5.3
GAN 5.3
hereditary ataxia 5.3
Charcot-Marie-Tooth disease 5.3
Joubert syndrome 5.2
Diabetic peripheral neuropathy 5.2
FHA 5.2
velocardiofacial syndrome 5.2
dyserythropoietic anemia 5.1
MBS 5.1
Goldstein 5.0
US1 5.0
Malignant glioma 4.9
kala-azar 4.8
BCM 4.8
Pick's disease 4.6
Tauopathies 4.6
CMT1A 4.6
sick building syndrome 4.5
pseudobulbar palsy 4.4
MEC 4.4
Aujeszky's disease 4.3
OPA1 4.2
LIN 4.2
NDI 4.2
pachygyria 4.2
sclerodactyly 4.1
motor neuron disease 4.1
BCH 4.1
Gilbert 4.1
MSS 4.1
polycystic kidney 4.0
Kartagener's syndrome 4.0
hereditary neuropathy 4.0
RP1 3.9
CLS 3.9
Harada 3.9
AAA 3.9
esophageal dysmotility 3.9
gangliosidosis 3.8
CHR 3.8
Recruitment 3.8
sensory neuropathy 3.8
optic atrophy 3.8
APL 3.8
EVA 3.8
Emery-Dreifuss muscular dystrophy 3.8
HTS 3.8
CUP 3.7
autonomic neuropathy 3.6
PBT 3.6
Testis 3.6
Testis 3.6
bone cancer 3.6
L. infantum 3.6
CAP 3.6
premalignant condition 3.5
EDC 3.5
monkeypox 3.4
vaccinia 3.4
megacolon 3.4
spastic diplegia 3.4
Sheehan's syndrome 3.4
AEM 3.3
PNS 3.3
HSP 3.3
KNO 3.3
Beard 3.3
Gardner's syndrome 3.3
Stomach 3.3
Stomach 3.3
Stomach 3.3
hand-foot syndrome 3.2
Orbit 3.2
leishmaniasis 3.2
DMT1 3.2
ATN 3.2
cutis laxa 3.2
Usher syndrome 3.2
X-linked agammaglobulinemia 3.2
Stomach 3.2
Huntington's disease 3.1
triploidy 3.1
amyotrophic lateral sclerosis 3.1
Tension 3.1
renal cyst 3.1
monoclonal gammopathy of undetermined significance 3.1
APL 3.1
Medulloblastoma 3.0
APL 3.0
osteopetrosis 3.0
Zellweger syndrome 3.0
peripheral neuropathy 3.0
PCT 2.9
TCC 2.9
MSA 2.9
retinitis pigmentosa 2.9
calcinosis 2.8
Hermansky-Pudlak syndrome 2.8
Cholangiocarcinoma 2.8
PSP 2.8
testicular atrophy 2.8
Wright 2.8
RGS 2.8
Dependence 2.8
bends 2.8
cervical adenocarcinoma 2.8
leukodystrophy 2.8
LMS 2.7
Dissociation 2.7
Fraser 2.7
abdominal aortic aneurysm 2.7
Cholangiocarcinoma 2.7
PTP 2.7
Testes 2.7
APC 2.6
nevoid basal cell carcinoma syndrome 2.6
NPC 2.6
brain cancer 2.6
more...
Symptom
dysosmia 6.1
female puberty 5.7
Fluctuation 5.4
fasciculation 5.1
disturbed balance 4.8
intention tremor 4.2
Halo 3.8
collapse 2.9
incoordination 2.8
Stiffness 2.7
hypertonia 2.3
spasticity 2.0
hypotonia 1.7
blurred vision 1.6
tense 1.5
paraparesis 1.2
dystonia 1.2
cancer pain 1.0
ophthalmoplegia 0.9
starvation 0.8
dysarthria 0.7
ataxia 0.7
myoclonus 0.6
numbness 0.3
ENT 0.3
lethargy 0.2
paresis 0.1
flushing -0.0
tremor -0.5
weakness -0.6
dizziness -0.6
seizures -0.9
stigma -1.1
angina -1.7
fatigue -2.0
pain -2.0
diarrhea -2.2
anesthesia -4.1
Drug
Monastrol 12.0
Propionamide 9.2
Ethylene Glycol 7.4
Benserazide 6.9
Velban 6.4
Compound 15 5.7
Dihydroergotamine 5.1
Taxol 4.8
CLS 4.4
Parkin 4.3
Parkin 4.3
Ranitidine 4.3
Tao 4.1
Orphan 3.6
TES 3.5
Docetaxel 3.4
ACT 3.1
Pravastatin 3.0
MAP 2.9
Alliance 2.8
Adenosine triphosphate 2.8
FLP 2.6
TAT 2.4
RFP 2.4
DPA 2.3
IL-1ra 2.2
Vitamin K 2.2
Gleevec 2.1
Mutagen 2.1
VCR 2.0
TAC 2.0
Activin 1.9
p75 1.7
Itraconazole 1.7
Propofol 1.6
DMI 1.6
Glycerol 1.5
Silica 1.4
Gel 1.4
Imatinib 1.3
Nitric Oxide 1.3
ETS 1.3
FAD 1.2
Alanine 1.2
SiO2 1.1
HCH 0.9
Kenyan 0.9
PCP 0.8
ROS 0.7
lysine 0.6
ABC 0.5
CAM 0.1
Asn 0.1
Leaf -0.2
DNase I -0.4
Biopolymers -0.4
ENT -0.4
nitroglycerin -0.5
IL-2 -0.6
Ethanol -0.6
CSF -1.3
Monit -1.5
vitamin E -1.5
caffeine -1.8
IFN-gamma -2.2
Dermatol -3.4
Enzyme
kinesin 12.6
tubulin GTPase 9.5
methylglutaconyl coenzyme A hydratase 9.5
tubulin carboxypeptidase 8.2
tubulin-tyrosine ligase 7.7
dynein ATPase 7.6
NSY 6.8
polo-like kinase 1 6.7
separase 6.5
guanylate kinase 6.4
6-phosphogluconolactonase 6.2
dynamin GTPase 5.9
transcarboxylase 5.8
AlkA 5.8
chitin synthase 5.4
MEKK1 5.2
VIP1 5.2
ATPase 5.2
CLK1 5.1
mannosidase II 5.0
tetanus neurotoxin 5.0
carboxypeptidase E 5.0
PIP kinase 5.0
TDH 4.8
beta-secretase 4.8
AMP-activated kinase 4.8
dihydropyrimidinase 4.5
triphosphatase 4.4
cellulose synthase 4.3
cellulose synthase 4.3
6-phosphofructo-2-kinase 4.3
subtilisin 4.2
GSK 4.1
apyrase 4.0
MAP 4.0
galactocerebrosidase 3.9
carnitine acetyltransferase 3.9
GRK2 3.9
ATP synthase 3.8
RNase III 3.6
carbonyl reductase 3.6
p80 3.5
HK2 3.5
myosin ATPase 3.5
CaMKII 3.5
cdc2 3.4
MTD 3.4
transketolase 3.3
enterokinase 3.2
phosphatidylinositol 4-kinase 3.2
glycerol kinase 3.1
Mg2+-ATPase 3.1
ClpP 3.0
m-calpain 3.0
sucrase-isomaltase 2.9
glutathione S-transferase 2.7
topoisomerase 2.7
proteasome 2.7
protein kinase 2.6
farnesyltransferase 2.6
MMP 2.6
calcineurin 2.6
proprotein convertase 2.5
phosphatidylinositol 3-kinase 2.5
GRK5 2.5
mitogen-activated protein kinase 2.5
TAT 2.4
Thy1 2.4
pyruvate kinase 2.3
topoisomerase 2.3
peroxiredoxin 2.3
myosin light chain kinase 2.2
purine nucleoside phosphorylase 2.2
phosphoinositide 3-kinase 2.1
MAT 2.1
farnesyltransferase 2.1
pyruvate carboxylase 2.1
P-glycoprotein 1.9
phosphoglucose isomerase 1.9
MAT 1.9
prostate-specific membrane antigen 1.8
prolyl hydroxylase 1.8
APC 1.8
MPP 1.8
thermolysin 1.7
RNA polymerase 1.7
adenylate kinase 1.7
DCF 1.7
chondroitinase 1.6
cholesterol acyltransferase 1.6
cathepsin B 1.6
choline acetyltransferase 1.6
chaperonin 1.5
chondroitinase 1.5
CAD 1.5
CAD 1.5
MEK 1.5
CAD 1.5
matrix metalloproteinase 2 1.4
sucrase 1.4
pectinase 1.4
AMPK 1.3
hexokinase 1.3
luciferase 1.2
firefly luciferase 1.2
ribonucleotide reductase 1.2
glucokinase 1.1
acetyl-CoA carboxylase 1.1
dihydrofolate reductase 1.1
ribonucleotide reductase 1.1
protein phosphatase 2A 1.1
ACS 1.0
ERK 1.0
furin 1.0
caspase-3 1.0
focal adhesion kinase 0.9
hexosaminidase 0.8
thymidylate synthase 0.8
NOS 0.8
PDE 0.8
enolase 0.8
arginase 0.8
caspase-9 0.8
PCP 0.8
phospholipase D 0.7
proteinase K 0.6
protein kinase C 0.6
cathepsin D 0.6
chitinase 0.6
AMP-activated protein kinase 0.5
glyceraldehyde-3-phosphate dehydrogenase 0.5
aldehyde dehydrogenase 0.5
glyceraldehyde-3-phosphate dehydrogenase 0.5
aldehyde dehydrogenase 0.5
aldehyde dehydrogenase 0.5
PARP 0.5
glyceraldehyde-3-phosphate dehydrogenase 0.4
transcriptase 0.4
adenylate cyclase 0.4
IKK 0.4
invertase 0.4
glutamine synthetase 0.3
chloramphenicol acetyltransferase 0.3
aldehyde dehydrogenase 0.3
glucose oxidase 0.2
RNase 0.2
chymotrypsin 0.2
glyceraldehyde-3-phosphate dehydrogenase 0.2
DNA polymerase 0.2
RNase 0.1
hyaluronidase 0.0
caspase-1 0.0
AMPK 0.0
glyceraldehyde-3-phosphate dehydrogenase -0.0
aldehyde dehydrogenase -0.0
caspase-8 -0.1
prostate-specific antigen -0.1
lipoprotein lipase -0.2
trypsin -0.2
beta-galactosidase -0.2
more...
Compound
4-(4-tert-butylphenyl)pyridine 12.6
2,3-dihydro-1-benzothiophene 1,1-dioxide 12.6
1-phenyl-3,5-pyrazolidinedione 11.6
S-tritylcysteine 10.0
Physodic acid 9.8
4-methylbenzamide 9.3
5-Iodotubercidin 9.0
5-Iodotubercidin 9.0
5-Iodotubercidin 9.0
5-Iodotubercidin 8.9
9H-fluoren-9-one 8.2
9H-fluoren-9-one 8.2
9H-fluoren-9-one 8.1
BeCl2 7.5
Lead nitrate 7.5
DNAP 7.5
9H-fluoren-9-one 7.4
BeF2 7.4
Latrunculin B 7.0
DNC 7.0
DNC 7.0
NCD 6.8
Velban 6.7
Psychosine 6.7
Nocodazole 6.5
DLG 6.5
PNP 6.3
hydroxy coumarin 6.2
Azobenzene 6.2
Sodium orthovanadate 5.6
AIR 5.5
PIPES 5.5
PIPES 5.5
PIPES 5.5
1,3-benzodioxole 5.5
Nitrobenzene 5.5
DNC 5.5
Clofibrate 5.4
sulfamic acid 5.3
sulfamic acid 5.3
Latrunculin A 5.2
ADP 5.2
ADP 5.2
ATP 5.2
OMPA 5.1
ADP 5.1
Tetracaine 5.1
NEM 5.0
propionamide 5.0
Parthenolide 5.0
propionamide 5.0
Brefeldin A 4.9
Brefeldin A 4.9
BCM 4.8
Parthenolide 4.7
2,5-hexanedione 4.7
ASK 4.7
sulfamic acid 4.7
Pentamidine 4.7
CLS 4.6
Trimethylamine N-oxide 4.5
Isoform 4.4
Cytochalasin D 4.4
MSL 4.3
3-(dimethylamino)propyl 4.3
Phalloidin 4.2
Vinca 4.2
GAP 4.2
SPD 4.1
DEK 4.0
Sorbitol 4.0
ASE 4.0
GTP 4.0
TES 3.9
GDP 3.9
AAA 3.9
HMM 3.9
CHIP 3.9
Morin 3.9
Colcemid 3.9
Dibutyryl cyclic AMP 3.9
Dibutyryl cyclic AMP 3.9
HCP 3.8
Docetaxel 3.8
Paclitaxel 3.7
Neutral Red 3.7
MAP 3.7
Gossypol 3.6
Gossypol 3.6
HCP 3.6
DETA 3.6
CAP 3.6
Phosphatidylinositol 3.5
40S 3.5
Glu-Glu 3.5
5-methylisoxazole 3.5
MBC 3.5
Pravastatin 3.4
Glycogen synthase 3.4
Neuronal 3.4
EDC 3.4
CAP 3.3
Amitriptyline 3.3
AMPA 3.3
APO 3.3
DBH 3.2
BAF 3.1
DDVP 3.1
Guanine 3.1
AMP 3.1
Histidine 3.1
LIN 3.1
Ins(1,4,5)P3 3.1
RELA 3.1
L-threonine 3.1
DEP 3.1
DOPE 3.0
Menadione 3.0
IDA 3.0
ENU 3.0
DPC 3.0
DPC 3.0
Cytochalasin B 3.0
LCR 3.0
Temozolomide 3.0
IPA 2.9
IPA 2.9
IPA 2.9
HIS 2.9
IPA 2.9
Polypeptide 2.9
pyridazine 2.9
pyridazine 2.9
ITC 2.9
Flux 2.9
DIC 2.9
TCC 2.8
Elastin 2.8
3-aminobenzamide 2.8
dimethylarsinic acid 2.8
dimethylarsinic acid 2.8
dimethylarsinic acid 2.8
Glutaraldehyde 2.8
dimethylarsinic acid 2.8
Purine 2.7
SAD 2.7
dihydrofolate 2.7
dimethylarsinic acid 2.7
DMA 2.7
DMA 2.7
DEP 2.7
Keratin 2.7
PSP 2.7
NPP 2.7
COS 2.6
Triton 2.6
dimethylarsinic acid 2.6
benzonitrile 2.5
DPA 2.5
DPA 2.5
more...