Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.4.1 (
myosin ATPase
)
1,140
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The addition of 15 mM caffeine to saponin-skinned human muscle fibers from M. vastus lateralis caused in the presence of 2 mM ATP an approx. 2-fold stimulation of respiration with glutamate+malate. This effect can be abolished by either the addition of the Ca2+ chelator EGTA, the inhibitor of Ca2+ transport
Ruthenium red
and the inhibitor of the
myosin ATPase
vanadate. The caffeine concentration dependency of respiration of fibers coincided with the caffeine-caused stimulation of
myosin ATPase
activity. The activation of oxidative phosphorylation in saponin-skinned human muscle fibers by caffeine can be explained by a stimulation of
myosin ATPase
caused by Ca2+ release from sarcoplasmic reticulum.
...
PMID:Mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers is stimulated by caffeine. 849 38
