Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.4.1 (
myosin ATPase
)
1,140
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
An inhibitor of
lipoxygenase
of arachidonic acid, nordihydroguaiaretic acid, shortens actin filaments, as judged by electron microscopic observation of negatively stained actin filaments, actin sedimentability and measurement of specific viscosity, at concentrations that inhibit the migration of phagocytic cells. At higher concentrations (more than 10 microM) nordihydroguaiaretic acid strikingly inhibits
myosin ATPase
activity. Thus nordihydroguaiaretic acid has a severe side effect on the cytoskeleton.
...
PMID:An inhibitor of lipoxygenase, nordihydroguaiaretic acid, shortens actin filaments. 642 4
