Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.4.1 (
myosin ATPase
)
1,140
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In this study we examined morphological and structural aspects of aponeurotic fragments from one patient with
Dupuytren
and Marfan diseases. Our purpose was to evaluate if characteristic features of
Dupuytren
aponeurosis are in some way influenced by alterations in collagenic and elastic bundles present in Marfan syndrome. So we compared histological, enzymatic and immunochemical features of tissue fragments from Marfan with similar fragments from simple
Dupuytren
patients. We observed a substantial difference in the predominant type of collagen which is adult type I in the normal
Dupuytren
disease and fetal type III in Marfan patient. Collagenic bundles are more dispersed in Marfan, and the whole aponeurosis seems less compact and resistant. No difference was observed in cellular populations of aponeurosis, and also myofibroblasts are present with abundant
myosin ATPase
activity both in Marfan with
Dupuytren
both in
Dupuytren
alone.
...
PMID:[Morphologic and hist-enzymatic aspects of palmar aponeurosis in a patient with Marfan syndrome associated with Dupuytren's contracture]. 262 43
