Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.3.44 (P-glycoprotein)
 13,344 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
P-glycoprotein 11.2
MDR protein 11.2
multidrug resistance-related protein 10.4
multidrug resistance associated protein 10.2
INE1 10.2
carboxylesterase 1A1 10.2
retina-specific ABC transporter 10.2
NG-TRA 10.2
breast cancer resistance protein 10.2
MDR1 10.2
MRK 10.0
mdr1 9.9
ABCB1 9.8
multidrug resistance-associated protein 9.8
Multidrug resistance associated protein 9.7
RUNDC3B 9.6
MGC4175 9.6
multidrug resistance-associated protein 7 9.6
MRP7 9.6
multidrug resistance protein 9.5
P-gp 9.5
MRP1 9.5
MDR2 9.5
multidrug resistance protein 1 9.5
BCRP 9.4
ABCC1 9.4
FBXO15 9.4
lanthionine synthetase C-like protein 1 9.2
Hbeta2 9.2
ABCC3 protein 9.2
FBXO21 9.2
ABCC10 protein 9.2
SH3GL1 9.2
MRP2 9.2
MDR3 9.1
canalicular multispecific organic anion transporter 9.1
LYC5 9.1
transmembrane transport protein 9.1
MRP5 9.0
multidrug resistance protein 2 9.0
ABCC10 9.0
MRP 9.0
Tac2-N 8.9
Phosphatidylinositol binding clathrin assembly protein 8.9
SARG 8.9
MRP-1 8.9
ABCC 8.8
ADR 8.8
MDR/TAP 8.8
NOMO 8.8
Multidrug resistance protein 1 8.8
MRP3 8.8
OATP4C1 8.7
GS-X 8.7
major vault protein 8.7
calveolin 8.6
TRDV3 8.6
HEP27 8.6
EKI 8.6
TrpC5 8.6
Breast Cancer Resistance Protein 8.6
ABCB5 8.6
MRP4 8.6
organic anion transporting polypeptide 8.5
OATP1B3 8.5
OATP2B1 8.5
ATP-binding cassette 8.4
ABCC2 8.4
ABCG2 8.4
ZO3 8.4
RASA4 8.4
ATP-binding cassette sub-family A member 3 8.4
ABCB4 protein 8.4
ABCG4 gene 8.4
CLDN12 8.4
solute carrier family 6 member 4 8.4
Multidrug resistance protein 8.4
MRP6 8.4
concentrative nucleoside transporter 1 8.3
carbonic anhydrase XII 8.2
more...
Disease
Erythrodysesthesia Syndrome 11.2
Drug-induced intrahepatic cholestasis 10.2
AD10 8.5
mouse leukemia P388 8.2
Schizophrenia and other psychotic disorders 7.8
FAB M0 7.5
PFIC2 7.4
Metastatic malignant melanoma 7.4
Erythroleukemia 7.2
NK-cell leukemia 7.0
uterine sarcoma 6.9
CEM 6.9
AO2 6.9
VIN 6.8
large cell lung cancer 6.5
de novo myelodysplastic syndromes 6.5
Dubin-Johnson syndrome 6.4
Intractable epilepsy 6.4
KHM 6.2
Intrahepatic cholestasis 6.2
Abnormal behavior 6.1
PPPP 6.1
childhood ANLL 6.0
Cerebral aspergillosis 6.0
secondary AML 5.9
Myelodysplastic Syndrome 5.8
stage III ovarian cancer 5.8
Cholestatic liver disease 5.8
Extranodal NK/T-cell lymphoma, nasal type 5.7
childhood rhabdomyosarcoma 5.6
Diaz 5.5
Adrenal gland 5.5
Adrenal gland 5.5
MCF 5.5
Mitochondrial DNA depletion 5.5
T/NK-cell lymphoma 5.4
B-cell prolymphocytic leukemia 5.3
LGMD2C 5.2
adult AML 5.1
Scott syndrome 5.1
intraocular retinoblastoma 5.1
ovarian serous cystadenocarcinoma 5.1
Friend leukemia 5.1
stage III breast cancer 5.1
Opioid dependence 5.0
Cortical dysplasia 4.9
NHD 4.9
FAB M2 4.9
VES 4.9
taste disorder 4.8
FAB M1 4.8
locally advanced cancer 4.8
Phototoxicity 4.8
CHEST 4.8
adrenocortical cancer 4.7
small cell lung cancer 4.7
myeloid leukemia 4.6
blast crisis 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
childhood ALL 4.6
erythroleukemia 4.6
alcoholic myopathy 4.5
AIDS/HIV 4.5
monocytic leukemia 4.5
chondroblastic osteosarcoma 4.5
sarcoma 180 4.4
epithelial ovarian cancer 4.4
BDB 4.4
Leukemia 4.4
pediatric medulloblastoma 4.4
acute myeloid leukemia 4.4
pediatric solid tumor 4.3
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Symptom
Severe diarrhea 5.4
renal pain 5.2
frequent urination 3.8
Fluctuation 3.0
Scratch 2.6
breakthrough pain 2.5
abdominal cramps 2.2
Decreased activity 2.2
adenitis 2.1
nasal congestion 2.1
pleuritic chest pain 2.0
leg edema 1.8
constipation 1.8
seizures 1.7
skin damage 1.7
cancer pain 1.6
analgesia 1.4
nausea 1.3
muscle rigidity 1.1
polydipsia 1.1
starvation 1.0
night sweats 1.0
dizziness 1.0
tingling 0.9
chronic constipation 0.9
diarrhea 0.9
tonic-clonic seizure 0.9
asthenia 0.8
Sedation 0.8
apathy 0.8
nausea and vomiting 0.8
bitter taste 0.8
hepatomegaly 0.7
polyuria 0.6
ataxia 0.4
vomiting 0.4
cerebellar ataxia 0.4
sleepiness 0.4
lethargy 0.3
hepatosplenomegaly 0.1
bradykinesia 0.0
paresthesia -0.1
hyperoxia -0.1
angina -0.1
insomnia -0.2
shoulder pain -0.2
hypothermia -0.3
paresis -0.3
syncope -0.4
bone pain -0.4
colic -0.4
flushing -0.4
spasticity -0.4
myalgia -0.5
anorexia -0.5
arthralgia -0.6
memory loss -0.6
acidity -0.7
acute pain -0.7
functional recovery -0.9
tremor -0.9
acute stress -1.0
splenomegaly -1.0
headache -1.1
numbness -1.1
pain -1.1
ENT -1.2
Ill -1.2
agitation -1.3
erythema -1.5
tinnitus -1.5
exhaustion -1.5
vertigo -1.6
fatigue -1.6
spasm -1.6
Welt -1.8
anesthesia -1.9
collapse -2.0
respiratory distress -2.0
low back pain -2.1
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Drug
Amdray 10.8
Tariquidar 10.6
Tocophersolan 10.2
Hectorol 10.2
Zosuquidar trihydrochloride 9.6
Edotecarin 9.6
ADR 8.8
VCR 8.5
Tandutinib 8.4
Nalfurafine hydrochloride 8.4
Ranimustine 8.4
Lanoxicaps 8.4
Tetrofosmin 8.2
Safingol 8.1
Pemirolast 7.9
Apafant 7.8
Cremophor RH40 7.6
Neotrofin 7.6
Ilmofosine 7.5
Oxycontin 7.5
Ixabepilone 7.4
2,4,6-Tribromophenol 7.4
Netupitant 7.3
Maribavir 7.3
Zyrtec 7.3
Hexitol 7.3
VCR 7.3
Cremophor EL 7.2
Zyrtec 7.2
Fangji 7.2
Trospium chloride 7.1
Sulfamide 7.1
Tykerb 7.0
Fosamprenavir 7.0
Accolate 7.0
Gramicidin D 6.9
Sulofenur 6.9
Idarubicin 6.8
Etravirine 6.8
Epothilone B 6.7
Flupenthixol 6.7
Adriamycin 6.6
Avasimibe 6.6
anti-CD33 6.6
ABC 6.6
Diclectin 6.6
Acrivastine 6.5
Berberine chloride 6.5
Istradefylline 6.5
Taxol 6.4
ADM 6.4
Atarax 6.4
Flavopiridol 6.3
Darunavir 6.3
Fluorescein sodium 6.3
Monastrol 6.3
Imodium 6.3
Moxidectin 6.3
Nimotop 6.3
Lumefantrine 6.2
Hyperforin 6.2
Quinine, 6.1
Miltefosine 6.1
Podophyllotoxin 6.1
Indinavir 6.1
Morphine hydrochloride 6.1
Agenerase 6.1
Trabectedin 6.0
Taxotere 6.0
Lonafarnib 6.0
Tedisamil 6.0
Imodium 5.9
TPV 5.9
Novantrone 5.9
Ephedrae Herba 5.9
Flesinoxan 5.9
Peppermint oil 5.8
Etoposide 5.8
Brij 30 5.8
Mevastatin 5.8
more...
Enzyme
P-glycoprotein 11.2
histidine permease 8.4
MDR 8.3
oligopeptidase A 7.8
CYP3A4 7.4
glucosylceramide synthase 7.1
6beta-hydroxylase 6.2
topoisomerase 6.0
topoisomerase 6.0
deoxycytidine deaminase 5.8
Mg2+-ATPase 5.7
deoxycytidine kinase 5.7
ornithine aminotransferase 5.4
sphingomyelin synthase 5.3
DHAD 5.2
FucT 5.0
thiopurine methyltransferase 4.9
bleomycin hydrolase 4.9
PHT 4.9
Protein 2 4.8
UDP-glucuronosyltransferase 4.8
ATPase 4.7
asparaginase 4.7
PTR1 4.5
thymidylate synthase 4.5
lactase-phlorizin hydrolase 4.5
GM3 synthase 4.5
methylenetetrahydrofolate dehydrogenase 4.5
dihydrodiol dehydrogenase 4.4
site-1 protease 4.4
HIV-1 protease 4.3
glycoprotease 4.3
gamma-glutamylcysteine synthetase 4.2
glutathione S-transferase 4.1
deoxyguanosine kinase 4.1
MTD 4.0
methylenetetrahydrofolate dehydrogenase 4.0
caspase-2 4.0
inosine triphosphatase 3.9
lactase-phlorizin hydrolase 3.9
caspase-6 3.9
dihydropyrimidine dehydrogenase 3.9
caspase-2 3.9
MsrA 3.9
caspase-6 3.8
oxaloacetate decarboxylase 3.8
CAO 3.8
dCMP deaminase 3.8
carboxylesterase 3.8
sphingosine kinase 3.7
CEP 3.7
poly(ADP-ribose) glycohydrolase 3.5
cysteine synthase 3.5
choline kinase 3.4
CGT 3.4
ALDH 3.4
methylthioadenosine phosphorylase 3.4
dihydrofolate reductase 3.4
formaldehyde dehydrogenase 3.3
caspase-9 3.3
dihydropyrimidine dehydrogenase 3.3
lysyl endopeptidase 3.3
cytosine deaminase 3.3
spermidine/spermine N1-acetyltransferase 3.3
reverse transcriptase 3.3
asparagine synthetase 3.3
PNGase F 3.2
TGT 3.2
endoglycosidase H 3.2
carbonyl reductase 3.2
PARP 3.2
MPP 3.2
tannase 3.2
chloramphenicol acetyltransferase 3.2
S-adenosyl-L-homocysteine hydrolase 3.1
caspase-8 3.1
CEP 3.1
DCF 3.1
protein kinase C 3.1
thymidylate kinase 3.1
more...
Compound
Lauroylcarnitine 11.2
Achillin 11.2
Dregamine 11.2
Dregamine 11.2
1-Propylagroclavine tartrate 11.2
SDZ PSC 833 10.9
Azidopine 10.3
C 494 10.2
C14H9NO2 10.2
1-bromo-4-chlorobutane 10.2
Estradiol-17beta-glucuronide 10.2
Phellamurin 10.2
Byakangelicin 9.6
Voacamine 9.6
Olivacine 9.6
C10H11NO2 9.6
2,2-diphenyl-1,3-dioxolane 9.2
Rhodamine 123 9.2
6-mercaptonicotinamide 9.1
Niguldipine 9.0
C15H10O4 8.9
N-methylbenzenesulfonamide 8.9
Mitraphylline 8.9
Pristinamycin IA 8.9
MK 571 8.8
LDS-751 8.8
benzo[a]phenazine 8.8
Silychristin 8.6
Rubrofusarin 8.6
Fexofenadine 8.6
4-methylpentanamide 8.4
Rubrofusarin 8.4
Eudesmin 8.4
3-furoic acid 8.4
Psorospermin 8.4
Mitox 8.3
Cinobufotalin 8.2
1-bromo-3-chloropropane 8.2
DCPM 8.2
Diphyllin 8.2
9H-thioxanthen-9-one 8.2
MDR 8.2
Vinca 8.2
OMCA 8.1
Cinchonine 8.1
Bergaptol 8.1
benzo[g]isoquinoline-5,10-dione 8.1
4,5,6,7-tetrahydro-1H-indole 8.1
Miracil D 8.1
Uvaol 8.1
Solutol HS 15 8.0
Coronaridine 7.9
Thaliblastine 7.9
1,4-anthracenedione 7.9
6H-indolo[2,3-b]quinoxaline 7.8
Miltirone 7.8
C7H10N2 7.8
BW 301U 7.8
NBD chloride 7.7
Saikosaponin A 7.7
ADR 7.6
Vinblastine 7.6
Colistin sulfate 7.5
No. 118 7.5
Verapamil 7.5
Glaucine 7.5
Sinensetin 7.4
Diphenoxylate 7.4
Tryptanthrin 7.4
Pachymic acid 7.4
Verapamil 7.4
Tetraphenylphosphonium 7.4
tetrachloroplatinum 7.3
Divinyl sulfone 7.3
tetrachloroplatinum 7.3
Ovatodiolide 7.3
Kaempferide 7.3
Mitragynine 7.3
Calcein 7.2
AR 1 7.2
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